Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:006290 (
ABL
)
4,280
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ABL
4280
BCR
3387
tyrosine kinase
1408
CML
306
Sep
304
Mol
222
BCR/ABL
215
BCR-ABL fusion
213
bcr
212
ALL
164
p210
159
JAK2
158
lymphoid
157
CD34
144
KIT
128
SRC
118
TEL
114
breakpoint cluster region
114
interferon
108
p190
107
more...
Disease
ABL
4280
chronic myeloid leukemia
2629
leukemia
1162
cancer
1049
acute lymphoblastic leukemia
545
tumor
402
Leukemia
338
blast crisis
326
acute myeloid leukemia
239
myeloproliferative disorders
227
lymphoma
198
minimal residual disease
172
leukemogenesis
114
chronic phase CML
101
residual disease
89
acute leukemia
79
polycythemia vera
73
tumorigenesis
68
essential thrombocythemia
66
B-ALL
63
more...
Symptom
splenomegaly
40
diarrhea
18
fatigue
12
nausea
9
anesthesia
7
vomiting
7
pain
6
hepatomegaly
6
headache
6
hepatosplenomegaly
6
muscle cramps
5
starvation
4
abdominal discomfort
4
erythema
4
respiratory distress
4
arthralgia
4
cough
3
exhaustion
3
dyspnea
3
anorexia
3
more...
Drug
Imatinib
422
Gleevec
243
Dasatinib
128
TEL
85
CSF
24
Bosutinib
22
G-CSF
19
lysine
13
ROS
11
Dermatol
10
Leaf
10
IL-2
10
IFN-gamma
8
Gefitinib
7
NVP
6
KCL
6
ETS
5
ABC
5
MAP
5
Herceptin
5
more...
Enzyme
focal adhesion kinase
4280
ERK
378
reverse transcriptase
120
mitogen-activated protein kinase
111
protein kinase
71
MEK
52
caspase-3
34
RNA polymerase
34
proteasome
32
BMT
28
transcriptase
26
CD10
21
P-glycoprotein
21
PARP
20
cdc2
17
protein kinase C
17
phosphatidylinositol 3-kinase
15
CD13
13
MDR
12
phosphoinositide 3-kinase
12
more...
Compound
ABL
4280
BCR
3387
tyrosine
373
DNA
341
Dec
306
Clin
255
ATP
95
TEL
85
oxygen
70
MEK
40
arginine
36
threonine
32
serine
30
retinoic acid
29
Tyrosine
28
glucose
25
methionine
21
calcium
19
MTT
19
phosphate
17
more...