Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:006221 (
synuclein
)
5,547
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
synuclein
5547
Mol
558
prion
328
ubiquitin
264
alpha-synuclein
262
Sep
261
SNCA
238
tyrosine hydroxylase
228
proteasome
183
NMR
156
glucocerebrosidase
145
ACS
140
axonal
140
DJ-1
126
LRRK2
123
TDP-43
118
olfactory
118
prion protein
118
amyloid precursor protein
117
endoplasmic reticulum
108
more...
Disease
Parkinson's disease
3899
Alzheimer's disease
904
dementia
633
parkinsonism
303
Dementia with Lewy bodies
206
cognitive impairment
142
movement disorder
140
neuroblastoma
140
amyotrophic lateral sclerosis
133
Huntington's disease
124
Multiple system atrophy
106
cancer
94
Gaucher disease
71
depression
57
progressive supranuclear palsy
55
tumor
50
diabetes
40
worms
40
Creutzfeldt-Jakob disease
38
SDS
38
more...
Symptom
tremor
73
bradykinesia
52
constipation
36
ataxia
27
cerebellar ataxia
25
motor symptom
15
seizures
13
collapse
13
dystonia
9
thinning
8
weakness
7
functional recovery
7
starvation
7
myoclonus
7
pain
6
memory loss
5
anosmia
5
fatigue
5
anesthesia
5
Stepping
4
more...
Drug
Parkin
84
Parkin
84
ROS
48
lysine
33
CSF
32
caffeine
19
vitamin E
7
ascorbate
6
ROC
5
RFP
4
IL-2
4
Reserpine
3
Rasagiline
3
L-tyrosine
3
Gel
3
NADH
3
Biopolymers
3
TAT
3
HCH
3
Ethanol
3
more...
Enzyme
tyrosine hydroxylase
217
proteasome
184
ACS
140
glucocerebrosidase
118
MPP
67
superoxide dismutase
60
mitogen-activated protein kinase
58
protein kinase
57
caspase-3
54
complex I
43
proteinase K
39
ATPase
35
focal adhesion kinase
34
ERK
28
luciferase
28
AMP-activated protein kinase
27
cathepsin D
23
monoamine oxidase
22
catalase
22
calcineurin
19
more...
Compound
Dec
275
oxygen
197
MPTP
165
iron
140
ACS
140
ACS
140
DNA
128
calcium
115
water
98
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
95
serine
95
copper
84
Clin
79
tyrosine
68
MPP
67
MPP
67
ATP
62
glutamate
54
L-DOPA
53
hydrogen
53
more...