Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:006221 (synuclein)
5,547 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
synuclein 5547
Mol 558
prion 328
ubiquitin 264
alpha-synuclein 262
Sep 261
SNCA 238
tyrosine hydroxylase 228
proteasome 183
NMR 156
glucocerebrosidase 145
ACS 140
axonal 140
DJ-1 126
LRRK2 123
TDP-43 118
olfactory 118
prion protein 118
amyloid precursor protein 117
endoplasmic reticulum 108
more...
Disease
Parkinson's disease 3899
Alzheimer's disease 904
dementia 633
parkinsonism 303
Dementia with Lewy bodies 206
cognitive impairment 142
movement disorder 140
neuroblastoma 140
amyotrophic lateral sclerosis 133
Huntington's disease 124
Multiple system atrophy 106
cancer 94
Gaucher disease 71
depression 57
progressive supranuclear palsy 55
tumor 50
diabetes 40
worms 40
Creutzfeldt-Jakob disease 38
SDS 38
more...
Symptom
tremor 73
bradykinesia 52
constipation 36
ataxia 27
cerebellar ataxia 25
motor symptom 15
seizures 13
collapse 13
dystonia 9
thinning 8
weakness 7
functional recovery 7
starvation 7
myoclonus 7
pain 6
memory loss 5
anosmia 5
fatigue 5
anesthesia 5
Stepping 4
more...
Drug
Parkin 84
Parkin 84
ROS 48
lysine 33
CSF 32
caffeine 19
vitamin E 7
ascorbate 6
ROC 5
RFP 4
IL-2 4
Reserpine 3
Rasagiline 3
L-tyrosine 3
Gel 3
NADH 3
Biopolymers 3
TAT 3
HCH 3
Ethanol 3
more...
Enzyme
tyrosine hydroxylase 217
proteasome 184
ACS 140
glucocerebrosidase 118
MPP 67
superoxide dismutase 60
mitogen-activated protein kinase 58
protein kinase 57
caspase-3 54
complex I 43
proteinase K 39
ATPase 35
focal adhesion kinase 34
ERK 28
luciferase 28
AMP-activated protein kinase 27
cathepsin D 23
monoamine oxidase 22
catalase 22
calcineurin 19
more...
Compound
Dec 275
oxygen 197
MPTP 165
iron 140
ACS 140
ACS 140
DNA 128
calcium 115
water 98
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 95
serine 95
copper 84
Clin 79
tyrosine 68
MPP 67
MPP 67
ATP 62
glutamate 54
L-DOPA 53
hydrogen 53
more...