Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:005480 (
BRCA1
)
9,253
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
BRCA1
9253
BRCA2
3726
p53
1220
Mol
808
PARP
656
ATM
613
Sep
558
RAD51
360
PALB2
318
Brca1
308
estrogen receptor
296
BRCA1 protein
288
BARD1
285
53BP1
276
HER2
258
CHEK2
249
PTEN
242
ubiquitin
227
H2AX
209
cancer susceptibility
196
more...
Disease
cancer
4628
breast cancer
4465
ovarian cancer
2531
tumor
2322
ATM
678
tumorigenesis
421
carcinoma
392
carcinogenesis
342
epithelial ovarian cancer
286
prostate cancer
222
anemia
217
Fanconi
204
MCF
155
colorectal cancer
145
metastases
137
tumor progression
124
APC
123
pancreatic cancer
113
carcinoma of the breast
108
adenocarcinoma
104
more...
Symptom
collapse
20
nausea
14
fatigue
13
discomfort
11
ataxia
9
menopausal symptoms
9
weakness
8
vomiting
8
pain
7
diarrhea
5
overweight
5
starvation
5
seizures
4
stigma
4
abdominal pain
4
asthenia
3
bloating
3
exhaustion
3
hot flashes
2
constipation
2
more...
Drug
lysine
69
BLM
57
ROS
23
Mutagen
15
GEO
13
ETS
10
ROC
9
Trabectedin
8
MAP
8
Paraffin
7
ABC
7
Gel
7
Dermatol
6
Adriamycin
6
caffeine
6
Taxol
5
Raloxifene
5
Monit
5
IFN-gamma
4
Estrogens
4
more...
Enzyme
PARP
697
ERK
474
APC
121
protein kinase
72
mitogen-activated protein kinase
68
proteasome
60
RNA polymerase
57
STK11
52
topoisomerase
51
topoisomerase
50
luciferase
44
focal adhesion kinase
34
endonuclease
33
DNA polymerase
28
glutathione S-transferase
28
ATPase
26
cdc2
26
caspase-3
18
DNA ligase
18
DNA ligase
18
more...
Compound
DNA
3821
Dec
647
Clin
451
ADP-ribose
163
ADP
121
MDA
108
ADP
100
ADP
99
lysine
93
oxygen
73
serine
66
BLM
58
methionine
42
zinc
40
tyrosine
38
threonine
38
arginine
35
Pac
33
Tamoxifen
30
hydrogen
30
more...