Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:003481 (
PLC
)
5,150
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PLC
5150
PKC
489
Mol
410
Sep
331
phosphatidylinositol-specific
318
phospholipase
293
tyrosine kinase
257
MAPK
177
PI3K
174
phosphoinositide-specific
157
ERK
153
ATP
150
ERK1
138
Phospholipase C
138
phospholipase D
135
GTP
133
PKA
133
insulin
132
epidermal growth factor
111
p38
105
more...
Disease
hepatocellular carcinoma
680
cancer
425
tumor
352
pertussis
148
hepatitis B
143
liver cancer
98
Toxic epidermal necrolysis
93
Stevens-Johnson syndrome
85
carcinoma
72
liver cancer
72
tumor growth
57
carcinogenesis
50
SDS
48
leukemia
47
breast cancer
40
hepatitis E
40
tumorigenesis
37
diabetes
36
Hepatocellular carcinoma
36
lymphoma
35
more...
Symptom
pain
35
starvation
15
collapse
9
exhaustion
8
analgesia
7
respiratory distress
6
bitter taste
6
fatigue
5
erythema
5
tremor
4
spasticity
4
seizures
4
anesthesia
4
nausea
3
discomfort
3
functional recovery
3
discomfort
3
acute stress
3
diarrhea
3
ataxia
3
more...
Drug
IL-2
41
MAP
34
ROS
24
Dermatol
24
Sorafenib
20
IFN-gamma
18
lysine
18
caffeine
18
Gel
16
Angiotensin II
16
ICI
14
CSF
12
PTH
11
Cardiovasc
11
Asn
10
Histamine
10
IFN-beta
9
MRC
9
Nephron
9
Forskolin
8
more...
Enzyme
phospholipase C
1685
protein kinase C
783
mitogen-activated protein kinase
464
protein kinase
319
ERK
295
phospholipase D
134
MEK
108
focal adhesion kinase
107
phosphatidylinositol 3-kinase
98
phospholipase A2
85
adenylate cyclase
65
thrombin
62
PI-PLC
61
caspase-3
48
lipase
47
ATPase
46
luciferase
38
glutathione S-transferase
35
trypsin
33
alkaline phosphatase
32
more...
Compound
calcium
968
tyrosine
606
Dec
375
DNA
334
phosphate
239
cAMP
219
ATP
153
GTP
134
glucose
126
acetate
123
sodium
122
water
120
oxygen
108
Clin
106
glutamate
79
MEK
75
ADP
73
Phosphatidylinositol
71
DAD
70
DAG
68
more...