Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: HUMANGGP:003457 (proteasome inhibitor)
4,748 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein proteasome inhibitor 4748 proteasome 2336 ubiquitin 958 Mol 481 Proteasome 280 Sep 278 p53 273 endoplasmic reticulum 270 caspase-3 234 Bcl-2 164 cytokine 143 histone deacetylase 129 p21 129 chymotrypsin-like 120 tumor necrosis factor 101 p65 100 p38 98 ATP 94 caspase-8 91 p27 91 more...

Disease cancer 1256 multiple myeloma 1066 tumor 711 leukemia 166 breast cancer 160 tumor growth 141 lymphoma 130 Parkinson's disease 119 mantle cell lymphoma 116 peripheral neuropathy 105 prostate cancer 86 carcinoma 76 hematologic malignancies 75 lung cancer 67 thrombocytopenia 67 tumorigenesis 65 hepatocellular carcinoma 60 colon cancer 57 neuroblastoma 56 MCF 55 more...

Symptom fatigue 36 diarrhea 27 pain 24 starvation 24 nausea 22 dyspnea 11 vomiting 11 weakness 10 seizures 8 collapse 8 cachexia 6 constipation 4 respiratory distress 4 numbness 3 erythema 3 ataxia 3 exhaustion 3 headache 3 bone pain 2 hyperoxia 2 more...

Drug Bortezomib 681 lysine 61 ROS 27 IFN-gamma 21 Parkin 19 Parkin 19 IL-2 18 Dermatol 14 Lenalidomide 14 Rituximab 11 Arsenic trioxide 11 MAP 9 Gel 9 caffeine 8 Revlimid 8 Etoposide 8 CSF 8 Cardiovasc 7 IFN-beta 7 ABC 6 more...

Enzyme proteasome 2336 mitogen-activated protein kinase 278 caspase-3 198 protein kinase 154 ERK 106 PARP 82 caspase-8 80 luciferase 74 MEK 60 trypsin 57 protein kinase C 50 focal adhesion kinase 48 caspase-9 46 ATPase 43 IKK 39 cdc2 37 glutathione S-transferase 31 superoxide dismutase 26 GSK 26 ubiquitin-protein ligase 23 more...

Compound DNA 435 Dec 325 oxygen 204 Clin 158 leucine 108 ATP 94 cysteine 89 lysine 80 tyrosine 79 alanine 75 glucose 73 serine 68 calcium 68 threonine 57 MDA 57 boron 57 Ubiquitin 54 TNF 54 nitric oxide 51 MTT 47 more...

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