Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:003324 (
anaplastic lymphoma kinase
)
1,986
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
anaplastic lymphoma kinase
1986
tyrosine kinase
403
epidermal growth factor receptor
329
ALK
294
nucleophosmin
164
CD30
159
EML4
145
Sep
140
echinoderm microtubule-associated protein-like
127
B23
113
receptor tyrosine kinase
113
ROS1
100
EGFR
99
Mol
96
p23
91
MET
80
lymphoid
76
BRAF
71
smooth muscle actin
48
Nucleophosmin
46
more...
Disease
tumor
645
cancer
582
lung cancer
522
non-small cell lung cancer
478
anaplastic large cell lymphoma
363
lymphoma
280
adenocarcinoma
210
lung carcinoma
132
Hodgkin's disease
118
neuroblastoma
98
metastases
85
tumorigenesis
76
IMT
74
sarcoma
73
T-cell lymphoma
72
carcinoma
67
brain metastases
57
T-cell lymphomas
53
tumor growth
48
B-cell lymphoma
46
more...
Symptom
diarrhea
15
nausea
12
dyspnea
12
cough
12
headache
11
abdominal pain
11
fatigue
10
vomiting
10
pain
9
anorexia
6
night sweats
5
weakness
5
hemoptysis
4
respiratory distress
4
chest pain
4
hepatosplenomegaly
4
exhaustion
3
constipation
3
nausea and vomiting
3
hoarseness
3
more...
Drug
ROS
34
Dermatol
12
CTC
6
NVP
6
Cardiovasc
6
EML
5
lysine
5
Pemetrexed
3
MAP
3
PDL
2
ABC
2
CAM
2
Monit
2
vitamin E
2
CSF
2
Paraffin
2
CTX
2
TAT
1
ETS
1
CER
1
more...
Enzyme
ERK
1986
mitogen-activated protein kinase
41
focal adhesion kinase
38
reverse transcriptase
27
MEK
16
granzyme B
14
phospholipase C
13
phosphatidylinositol 3-kinase
12
protein kinase
12
caspase-3
10
p80
10
proteasome
10
CYP3A4
8
lactate dehydrogenase
7
CD10
7
RNA polymerase
6
NOS
6
phosphoinositide 3-kinase
6
thymidylate synthase
6
succinate dehydrogenase
5
more...
Compound
Clin
197
tyrosine
132
Dec
115
DNA
109
methionine
90
ATP
30
MEK
15
His
12
hydrogen
10
Phe
10
oxygen
7
leucine
7
serine
7
pyrimidine
7
pyrimidine
7
lysine
6
MTT
6
CLTC
6
water
5
ACS
5
more...