Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:001890 (PERK)
 1,824 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PERK 1824
endoplasmic reticulum 1207
CHOP 542
ATF6 447
ATF4 375
IRE1 367
GRP78 326
Mol 208
caspase-3 190
BiP 163
PKR 158
XBP1 155
JNK 129
insulin 121
C/EBP homologous protein 119
Bcl-2 119
Sep 98
GCN2 74
mTOR 71
IRE 71
more...
Disease
cancer 319
tumor 203
diabetes 110
Alzheimer's disease 61
obesity 55
ischemia 53
tumor growth 48
breast cancer 47
type 2 diabetes 45
tumorigenesis 38
hepatocellular carcinoma 36
melanoma 30
GSH 29
hyperglycemia 28
virus infection 27
colon cancer 26
fatty liver 26
tumor progression 25
neuroblastoma 23
Parkinson's disease 23
more...
Symptom
starvation 34
functional recovery 12
pain 4
seizures 4
diarrhea 3
weakness 3
hyperoxia 2
overweight 2
acute stress 2
cachexia 2
ataxia 2
chronic constipation 1
hypothermia 1
dystonia 1
constipation 1
Neuropathic pain 1
acidity 1
dizziness 1
exhaustion 1
collapse 1
more...
Drug
ROS 65
Parkin 9
Parkin 9
Bortezomib 6
lysine 5
Monit 5
ZnO 4
RFP 3
Liraglutide 3
Sorafenib 3
vitamin E 3
Ethanol 3
3-Methyladenine 3
Cardiovasc 2
Aloe 2
FAD 2
Vitamin E 2
Nitric Oxide 2
Portal 2
NADH 2
more...
Enzyme
protein kinase 255
mitogen-activated protein kinase 193
caspase-3 148
PARP 62
proteasome 47
ERK 46
AMP-activated protein kinase 44
superoxide dismutase 35
AMPK 34
AMPK 34
caspase-9 34
focal adhesion kinase 24
caspase-8 23
ATPase 21
catalase 19
GSK 19
MEK 17
lactate dehydrogenase 17
caspase-4 17
alanine aminotransferase 16
more...
Compound
oxygen 194
glucose 139
Dec 110
calcium 97
DNA 96
ATF 68
ATP 50
TNF 38
serine 37
MDA 32
water 31
MTT 30
GSH 29
GSH 29
N-acetylcysteine 29
nitric oxide 24
cysteine 24
Tunicamycin 22
BIP 21
dUTP 20
more...