Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:001716 (E3 ubiquitin ligase)
 5,677 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
E3 ubiquitin ligase 5677
ubiquitin 1409
proteasome 994
Mol 679
p53 472
ubiquitin ligase 352
SCF 325
Sep 314
Parkin 235
endoplasmic reticulum 202
Ubiquitin 190
F-box protein 176
APC 167
parkin 153
cytokine 148
interacting protein 144
MDM2 144
Skp1 137
cullin 136
adaptor protein 128
more...
Disease
cancer 910
tumor 651
tumorigenesis 300
Parkinson's disease 234
breast cancer 179
APC 167
Hippel 160
HIV 111
virus infection 97
tumor growth 94
carcinogenesis 85
leukemia 84
tumor progression 84
prostate cancer 72
parkinsonism 68
immunodeficiency 66
pruritus 64
PARK2 61
herpes simplex 60
lung cancer 54
more...
Symptom
starvation 34
seizures 18
ataxia 17
pain 15
cachexia 8
weakness 7
collapse 7
stigma 4
hypotonia 4
hepatomegaly 3
thinning 3
exhaustion 3
Halo 2
dyspnea 2
hyperoxia 2
respiratory distress 2
facial droop 1
cyanosis 1
diarrhea 1
spasticity 1
more...
Drug
lysine 252
Parkin 235
Parkin 235
Lenalidomide 17
ROS 17
Dermatol 13
IL-2 12
HCH 10
Retinoic acid 7
IFN-beta 6
Activin 5
Bortezomib 4
ROC 4
MAP 4
p75 4
ETS 4
Gel 4
MDS 4
IFN-gamma 3
ascorbate 3
more...
Enzyme
proteasome 994
mitogen-activated protein kinase 185
protein kinase 181
APC 173
ERK 114
focal adhesion kinase 66
ATPase 63
IKK 61
luciferase 52
calcineurin 47
cdc2 45
MEK 41
protein kinase C 37
AMP-activated protein kinase 30
glutathione S-transferase 29
caspase-3 28
RNA polymerase 27
GSK 25
phosphatidylinositol 3-kinase 23
prolyl hydroxylase 23
more...
Compound
DNA 741
Dec 370
lysine 330
Cbl 176
oxygen 172
tyrosine 133
serine 102
glucose 99
threonine 88
cysteine 86
Clin 80
CHIP 76
Ubiquitin 75
zinc 74
TNF 60
salt 59
calcium 57
leucine 57
arginine 55
ATP 53
more...