Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:001566 (
CFTR
)
2,822
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CFTR
2822
Mol
368
cystic fibrosis transmembrane conductance regulator
321
chloride channel
236
ATP
201
Sep
188
Pseudomonas
135
endoplasmic reticulum
115
ATPase
96
ENaC
82
PKA
66
AMP
53
ABC
51
pancreatic secretory trypsin inhibitor
43
IL-8
43
cytokine
41
Calu
40
ATP-binding cassette
39
PRSS1
38
ABCC7
35
more...
Disease
cystic fibrosis
1728
lung disease
161
pancreatitis
68
cancer
65
pancreatic insufficiency
56
chronic pancreatitis
55
diabetes
45
dehydration
37
infertility
33
ileus
33
azoospermia
31
asthma
30
male infertility
29
genetic disorder
29
chronic obstructive pulmonary disease
28
bronchiectasis
27
tumor
26
liver disease
25
polycystic kidney
23
epididymis
21
more...
Symptom
diarrhea
38
cough
12
pain
12
respiratory distress
6
hemoptysis
5
acidity
5
hepatomegaly
4
discomfort
3
starvation
3
microbial colonization
3
hypercapnia
3
discomfort
3
constipation
3
chronic cough
2
Respiratory symptoms
2
splenomegaly
2
abdominal pain
2
functional recovery
2
headache
2
anesthesia
2
more...
Drug
ABC
51
Forskolin
21
lysine
13
DNase I
12
ROS
10
IFN-gamma
5
Amiloride
5
Amiloride
5
lactose
4
Miglustat
4
Bumetanide
4
ascorbate
3
Secretin
3
CSF
3
Alliance
3
IL-2
3
CFT
3
Ringer's solution
2
Sodium phenylbutyrate
2
Denufosol tetrasodium
2
more...
Enzyme
protein kinase
128
ATPase
96
P-glycoprotein
36
protein kinase C
35
proteasome
30
mitogen-activated protein kinase
28
ERK
27
trypsin
17
luciferase
16
phosphodiesterase
16
AMPK
16
adenylate cyclase
15
AMP-activated protein kinase
14
reverse transcriptase
12
beta-galactosidase
11
carbonic anhydrase
11
guanylate cyclase
10
MDR
10
phospholipase C
9
AMPK
9
more...
Compound
cAMP
323
DNA
243
ATP
201
Dec
186
sodium
136
Clin
126
calcium
116
water
111
Phe
75
salt
72
HCO
60
carbonate
57
AMP
54
DIDS
35
chlorine
31
cysteine
31
NPPB
30
glucose
29
oxygen
28
cGMP
25
more...