Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:001381 (ubiquitin ligase)
 5,296 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ubiquitin ligase 5296
ubiquitin 1683
proteasome 974
Mol 751
SCF 586
p53 411
E3 ubiquitin ligase 352
Sep 332
APC 292
F-box protein 254
Ubiquitin 243
Skp1 237
endoplasmic reticulum 222
cullin 201
cyclin 141
Skp2 137
Parkin 127
histone 124
p27 123
anaphase-promoting complex/cyclosome 115
more...
Disease
cancer 750
tumor 567
APC 293
tumorigenesis 214
Parkinson's disease 140
breast cancer 130
Hippel 102
carcinogenesis 88
HIV 87
tumor progression 54
virus infection 53
Alzheimer's disease 53
tumor growth 51
immunodeficiency 49
ATM 46
leukemia 45
Angelman syndrome 44
prostate cancer 44
hepatocellular carcinoma 43
parkinsonism 43
more...
Symptom
starvation 32
seizures 31
ataxia 20
collapse 12
cachexia 9
weakness 6
exhaustion 5
pain 5
myoclonus 4
respiratory distress 4
dysarthria 2
acute stress 2
fatigue 2
cerebellar ataxia 2
HSA 2
dystonia 2
anesthesia 2
hypotonia 1
intention tremor 1
Scratch 1
more...
Drug
lysine 217
Parkin 127
Parkin 127
ROS 13
IL-2 8
Dermatol 8
Cardiovasc 7
Retinoic acid 7
ETS 6
MAP 6
Kenyan 6
CSF 5
ROC 5
p75 5
Alanine 4
BLM 4
Lenalidomide 4
HCH 4
Bortezomib 4
ICI 4
more...
Enzyme
proteasome 974
APC 302
protein kinase 223
mitogen-activated protein kinase 149
ERK 99
ATPase 90
cdc2 77
calcineurin 58
RNA polymerase 55
ubiquitin-protein ligase 51
focal adhesion kinase 46
IKK 46
luciferase 31
AMP-activated protein kinase 29
caspase-3 28
glutathione S-transferase 28
protein kinase C 27
GSK 25
MEK 24
polo-like kinase 1 23
more...
Compound
DNA 772
Dec 373
lysine 286
Cbl 200
tyrosine 141
oxygen 118
Ubiquitin 115
serine 112
CHIP 88
glucose 88
threonine 80
cysteine 70
arginine 69
ATP 62
zinc 59
alanine 59
leucine 55
calcium 55
sodium 52
proline 46
more...