Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:001291 (
MAP kinase
)
8,816
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAP kinase
8816
mitogen-activated protein
2022
MEK
1162
ERK
1098
p38
1064
Mol
1037
ERK1
927
MAPK
728
MAP
708
JNK
650
Sep
643
p42
600
p38 MAP kinase
498
phosphatase
491
p44
481
tyrosine kinase
468
cytokine
457
ERK2
447
insulin
422
threonine
394
more...
Disease
cancer
685
tumor
507
pertussis
185
breast cancer
173
tumorigenesis
130
melanoma
124
carcinoma
106
Alzheimer's disease
106
hypertension
89
ischemia
87
leukemia
86
carcinogenesis
86
tumor growth
82
diabetes
80
atherosclerosis
80
hepatocellular carcinoma
78
MCF
72
prostate cancer
65
neuroblastoma
64
adenocarcinoma
55
more...
Symptom
starvation
60
pain
29
seizures
26
diarrhea
9
hyperoxia
7
fatigue
7
exhaustion
5
nausea
5
respiratory distress
5
anesthesia
5
ataxia
4
cachexia
4
arthralgia
3
functional recovery
3
acute stress
3
collapse
3
analgesia
3
dyspnea
3
headache
3
angina
2
more...
Drug
MAP
719
IL-2
55
Angiotensin II
52
ROS
46
CSF
42
lysine
41
ETS
37
Dermatol
28
IFN-gamma
26
ICI
22
Forskolin
20
caffeine
19
ETA
14
Cardiovasc
14
Ethanol
14
Growth hormone
13
Activin
13
EE2
13
Growth hormone
13
vitamin E
11
more...
Enzyme
mitogen-activated protein kinase
8816
MEK
1470
ERK
1400
protein kinase
1156
protein kinase C
785
MAP
708
focal adhesion kinase
244
MEKK1
222
phosphatidylinositol 3-kinase
218
calcineurin
174
phospholipase C
152
cdc2
133
caspase-3
99
luciferase
95
thrombin
77
NADPH oxidase
68
proteasome
68
AMPK
58
NADPH oxidase
57
glutathione S-transferase
57
more...
Compound
tyrosine
1213
DNA
742
MEK
716
MAP
708
Dec
647
calcium
591
threonine
519
serine
469
cAMP
395
oxygen
311
acetate
254
glucose
182
ATP
169
sodium
158
GTP
143
nitric oxide
133
TNF
126
phosphate
117
Insulin
116
AMP
107
more...