Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:000877 (MDM2)
 4,163 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MDM2 4163
p53 3176
p21 466
Mol 403
CDK4 374
MDM2 protein 279
MDMX 229
ubiquitin 224
Sep 220
proteasome 181
ARF 174
E3 ubiquitin ligase 144
p16 143
MDM4 139
mutant p53 137
Bcl-2 133
INK4a 125
caspase-3 120
tumour suppressor 118
AKT 118
more...
Disease
cancer 1703
tumor 1461
tumorigenesis 272
liposarcoma 236
breast cancer 195
ARF 174
sarcoma 155
carcinogenesis 149
tumor growth 140
carcinoma 139
retinoblastoma 114
tumor progression 112
lung cancer 103
hepatocellular carcinoma 101
osteosarcoma 99
ATM 97
metastases 96
melanoma 90
leukemia 88
prostate cancer 86
more...
Symptom
fatigue 5
vomiting 5
starvation 5
ataxia 4
collapse 4
nausea 4
diarrhea 4
pain 3
epigastric pain 3
decreased appetite 3
anorexia 2
weakness 2
dyspnea 2
exhaustion 2
functional recovery 2
chest pain 2
hoarseness 1
wrist pain 1
headache 1
Anoxia 1
more...
Drug
lysine 46
ROS 26
MDM 20
PFT 13
NVP 12
CPM 10
Dermatol 9
caffeine 8
p75 7
Mutagen 6
Paraffin 5
Adriamycin 5
Arsenic trioxide 5
EE2 5
Gel 4
MAP 4
Etoposide 4
IL-2 4
ETS 4
GEO 4
more...
Enzyme
ERK 281
proteasome 181
mitogen-activated protein kinase 101
caspase-3 96
protein kinase 75
PARP 52
focal adhesion kinase 48
luciferase 47
cdc2 42
MEK 28
caspase-9 27
phosphatidylinositol 3-kinase 25
APC 17
protein kinase C 17
RNA polymerase 16
glutathione S-transferase 16
alanine aminotransferase 16
reverse transcriptase 16
calcineurin 15
ACS 14
more...
Compound
DNA 881
Dec 296
urea 180
Clin 81
serine 59
oxygen 57
lysine 57
arginine 56
MTT 45
alanine 34
threonine 29
methionine 29
MDA 28
tyrosine 26
zinc 25
glucose 23
MEK 22
hydrogen 22
cysteine 20
water 19
more...