Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:000528 (
proteasome
)
26,143
document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
proteasome
26143
ubiquitin
11078
Mol
3294
proteasome inhibitor
2336
endoplasmic reticulum
1697
Sep
1549
p53
1138
Ubiquitin
1087
Proteasome
1033
E3 ubiquitin ligase
994
ATP
992
ubiquitin ligase
974
ATPase
753
chymotrypsin-like
673
caspase-3
512
SCF
476
cytokine
475
insulin
463
MHC class I
461
mTOR
407
more...
Disease
cancer
4261
tumor
2401
multiple myeloma
1369
Parkinson's disease
827
Alzheimer's disease
705
breast cancer
597
tumorigenesis
479
leukemia
419
muscular atrophy
397
tumor growth
384
HIV
319
hepatocellular carcinoma
311
amyotrophic lateral sclerosis
290
prostate cancer
274
Huntington's disease
271
carcinogenesis
270
diabetes
267
carcinoma
239
virus infection
238
lymphoma
224
more...
Symptom
starvation
252
cachexia
170
ataxia
88
weakness
81
pain
56
collapse
45
fatigue
41
seizures
31
anorexia
28
diarrhea
21
tremor
18
exhaustion
16
functional recovery
15
respiratory distress
12
dystonia
12
nausea
10
memory loss
9
acute stress
9
headache
9
bradykinesia
9
more...
Drug
lysine
582
Bortezomib
544
Parkin
155
Parkin
155
IFN-gamma
133
ROS
126
Cardiovasc
65
AMC
55
MAP
36
Dermatol
34
IL-2
32
Asn
32
CSF
26
ascorbate
25
NADH
22
vitamin E
21
Gel
20
Lenalidomide
19
Leaf
18
Arsenic trioxide
17
more...
Enzyme
proteasome
26143
protein kinase
843
mitogen-activated protein kinase
830
ATPase
778
ERK
423
caspase-3
415
trypsin
409
focal adhesion kinase
204
APC
200
protein kinase C
193
luciferase
192
cdc2
187
ubiquitin-protein ligase
186
MEK
176
IKK
172
RNA polymerase
162
calcineurin
140
chymotrypsin
136
PARP
135
glutathione S-transferase
123
more...
Compound
DNA
2393
Dec
1807
ATP
992
oxygen
912
lysine
762
Ubiquitin
614
serine
510
tyrosine
483
leucine
433
threonine
433
glucose
406
cysteine
398
calcium
397
Clin
397
alanine
336
arginine
272
AAA
219
TNF
194
nitric oxide
185
sodium
179
more...