Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:000055 (insulin receptor)
 9,597 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin receptor 9597
insulin 8074
IRS-1 1426
tyrosine kinase 1221
Mol 814
Sep 639
insulin-like growth factor 524
phosphatidylinositol 3-kinase 510
IGF-I 367
ATP 366
glucose transporter 335
GLUT4 330
insulin receptor substrate 322
IGF-I receptor 308
IRS-2 292
protein kinase B 279
Insulin receptor 278
p85 263
IGF-1 254
AKT 250
more...
Disease
diabetes 1796
type 2 diabetes 854
obesity 799
hyperinsulinemia 502
cancer 473
hyperglycemia 436
tumor 278
glucose intolerance 267
hepatocellular carcinoma 259
Alzheimer's disease 205
metabolic syndrome 181
hypoglycemia 175
hypertension 143
breast cancer 141
leprechaunism 123
acanthosis nigricans 115
polycystic ovary syndrome 112
SDS 92
fatty liver 81
cardiovascular disease 80
more...
Symptom
starvation 49
overweight 34
pain 10
fatigue 10
seizures 10
cachexia 9
hepatomegaly 8
anesthesia 8
polyuria 8
polydipsia 6
masculinization 6
weakness 6
memory loss 5
exhaustion 4
hypothermia 4
functional recovery 3
diarrhea 3
anorexia 3
hyperoxia 2
abdominal pain 2
more...
Drug
lysine 69
MAP 39
Asn 34
Glucagon 26
DM1 25
Gel 21
Growth hormone 17
Growth hormone 17
ROS 17
ADM 17
Cardiovasc 15
NVP 12
Dermatol 11
Angiotensin II 10
Fructose 10
Alanine 9
vitamin E 8
Troglitazone 8
Rosiglitazone 7
IL-2 7
more...
Enzyme
mitogen-activated protein kinase 679
phosphatidylinositol 3-kinase 515
protein kinase 514
ERK 375
protein kinase C 293
focal adhesion kinase 214
phosphoinositide 3-kinase 120
AMP-activated protein kinase 113
trypsin 110
PTPase 99
MEK 91
GSK 88
glucokinase 86
phosphoenolpyruvate carboxykinase 81
phosphoenolpyruvate carboxykinase 65
AMPK 64
phosphoenolpyruvate carboxykinase 64
calcineurin 60
glutathione S-transferase 56
glucose-6-phosphatase 48
more...
Compound
glucose 3107
Insulin 2127
tyrosine 2081
Dec 683
Clin 536
serine 512
DNA 508
ATP 366
threonine 320
sodium 226
phosphate 181
calcium 169
water 156
Phe 156
sulfate 139
galactose 131
alanine 129
arginine 125
lysine 118
oxygen 115
more...