Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.5.1.2 (DNA ligase)
 2,749 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DNA repair enzyme 13.5
polynucleotide ligase 13.5
DNA ligase 13.5
bromodomain containing 2 13.5
ZNF433 12.5
homeobox D1 12.5
DNA ligase I 12.1
polyhomeotic 2 11.9
ALKBH8 11.5
DNA ligase III 11.5
EYA1 protein 11.2
X-ray repair cross-complementing protein 1 11.1
LIG3 11.1
Tyrosyl-DNA phosphodiesterase 1 11.1
DNA ligase 1 10.9
ALKBH2 10.9
Pol lambda 10.8
H2A.X protein 10.7
LIG1 10.7
tyrosyl-DNA phosphodiesterase 1 10.6
Uracil-DNA glycosylase 10.5
FAM129B 10.5
putative exonuclease 10.5
IMPAD1 10.3
XRCC1 protein 10.3
PNK 10.2
CYC4 10.2
TFIP11 10.2
AP lyase 10.1
LIG 10.1
DNA binding peptide 10.0
DNA ligase IV 10.0
X-ray repair cross-complementing protein 4 9.9
SSRP1 protein 9.9
CD3EAP 9.8
ABH2 9.8
class I homeobox 9.7
beta-polymerase 9.7
O6-methylguanine-DNA methyltransferase 9.7
hRad50 9.6
XRCC4 protein 9.6
MNSFbeta 9.6
DNA polymerase beta 9.6
LIG4 9.6
DNA polymerase lambda 9.5
uracil-DNA glycosylase 9.5
aprataxin 9.4
Pol mu 9.4
VBP1 9.3
CMH-1 9.3
NEIL1 9.3
hOGG1 9.2
ART3 9.2
TP53I3 9.2
TDP1 9.1
recombination repair protein 9.1
single strand DNA-binding protein 9.1
Ribosomal protein S3 9.0
OGG1 9.0
ART4 9.0
photolyase 9.0
FEN1 9.0
UNG2 9.0
endonuclease III 9.0
AlkB 8.9
PAF49 8.9
CNOT6L 8.9
Poly(ADP-ribose)polymerase 8.8
methylguanine-DNA methyltransferase 8.8
XRCC4 8.8
tripartite motif-containing 24 8.8
DNA primase 8.8
NEIL2 8.8
NPCR 8.7
UHRF2 8.7
p53-inducible protein 8.7
XRCC1 8.7
ALKBH3 8.7
PPP1R13L 8.7
Methylguanine-DNA methyltransferase 8.7
more...
Disease
SCAN1 10.5
Xeroderma 9.0
MYH-associated polyposis 8.4
CRV 8.2
Steroid 21-hydroxylase deficiency 8.1
TGCT 7.6
alcoholic dementia 7.3
Fowlpox 7.2
functioning pituitary adenoma 7.0
Lederer 6.8
Malignant glioma 6.7
brittle hair 6.7
pediatric medulloblastoma 6.7
XPG 6.6
XDP 6.5
RPC 6.4
POH 6.4
xeroderma pigmentosum 6.3
poikiloderma 6.3
Shope fibroma 6.3
Ureteral obstruction 6.2
GAN 6.2
African swine fever 6.1
hereditary ataxia 6.1
metastatic neuroblastoma 6.1
XPD 6.1
XP-A 6.1
BLM 6.0
trichothiodystrophy 6.0
Cockayne syndrome 5.9
HNA 5.8
infectious arthritis 5.7
FHA 5.5
AHL 5.5
vaccinia 5.4
XPF 5.4
metastatic neuroblastoma 5.4
anaplastic astrocytoma 5.3
kidney tumor 5.3
CLN1 5.2
HIV encephalitis 5.1
cancer relapse 5.0
chronic phase CML 5.0
CLN2 5.0
SMC 4.9
Spinocerebellar ataxia 4.9
AOA 4.8
RP1 4.8
pellagra 4.8
RP11 4.8
propionic acidemia 4.7
WRN 4.7
MRD 4.7
Allergic asthma 4.7
MPE 4.7
CP1 4.6
glioblastoma 4.6
benign nevi 4.6
Primary effusion lymphoma 4.6
21-hydroxylase deficiency 4.5
progeria 4.4
premalignant condition 4.4
Fanconi syndrome 4.4
TBS 4.4
oligodendroglioma 4.4
IS1 4.3
monkeypox 4.3
NMS 4.2
AEM 4.2
asbestosis 4.2
GCT 4.2
apraxia 4.0
glioblastoma multiforme 4.0
Whipple's disease 4.0
acute nonlymphocytic leukemia 4.0
RP4 4.0
bends 4.0
Human immunodeficiency virus type 4.0
MCS 4.0
African trypanosomiasis 4.0
more...
Symptom
skin damage 5.3
hyperoxia 3.5
ataxia 3.5
acute stress 2.3
erythema 1.8
memory loss 1.7
starvation 0.5
constipation 0.2
thinning 0.0
back pain -0.1
functional recovery -0.2
collapse -0.3
hypothermia -0.6
angina -0.9
nausea -1.0
fatigue -2.2
seizures -2.8
anesthesia -3.3
pain -4.5
Drug
Anthramycin 9.2
Adozelesin 8.7
Gliadel 7.5
Fotemustine 7.5
Pyridostigmine bromide 7.3
Truvada 7.1
Domin 7.1
Pyridostigmine bromide 7.0
Sodium acetate 6.8
3-Methyladenine 6.1
Truvada 6.0
-deoxyadenosine 5.9
Arsenic trioxide 5.2
Etoposide 4.9
Orlistat 4.9
Tenofovir 4.8
BLM 4.7
Alanine 4.6
Fludarabine 4.6
Zoledronic acid 4.5
Dihydro 4.5
Imiquimod 4.5
CED 4.3
DNase I 4.3
Dasatinib 4.3
niacin 4.2
Glide 4.2
Riboflavin 3.9
PMPA 3.9
Zoledronic acid 3.9
BoNT/A 3.7
Adenosine triphosphate 3.7
Oxaliplatin 3.7
Monensin 3.6
Mutagen 3.5
AraC 3.4
Asn 3.4
Doxycycline 3.4
ABC 3.4
Fragment 3.3
Gel 3.2
Methylene blue 3.2
Pronase 3.2
ZnCl2 3.1
ZnCl2 3.1
NBT 3.1
lysine 3.0
ROS 3.0
balanced salt solution 2.9
Adriamycin 2.9
VCR 2.9
Biopolymers 2.8
MRC 2.8
9-THC 2.7
Docetaxel 2.7
TTC 2.6
ampicillin 2.6
G418 2.4
CDP 2.3
TAT 2.3
AZT 2.1
Glutathione 2.1
FAD 2.1
ALA 2.0
IFN-beta 1.9
AZT 1.9
Vitamin A 1.9
ADM 1.9
NADH 1.4
Angiotensin II 1.2
CTX 1.2
G-CSF 1.1
ICI 1.1
caffeine 1.1
lactose 1.1
CaCl2 0.9
CaCl2 0.9
CaCl2 0.8
NH3 0.7
ascorbate 0.6
more...
Enzyme
DNA ligase 13.5
DNA ligase 13.5
DNase V 12.7
DNA 3'-phosphatase 10.7
endonuclease V 10.6
NMN deamidase 10.5
3-methyladenine DNA glycosylase I 10.4
exodeoxyribonuclease 10.3
polynucleotide kinase 10.3
hypoxanthine-DNA glycosylase 10.0
endodeoxyribonuclease 10.0
3'-phosphatase 9.8
Fpg protein 9.7
AP lyase 9.7
dCTPase 9.5
L-serine hydro-lyase 9.5
RNA ligase 9.5
EC 3.6.1.29 9.4
dCMP hydroxymethylase 9.2
Escherichia coli exonuclease III 9.2
endonuclease VII 9.1
AlkA 8.7
ethylbenzene dehydrogenase 8.6
dGTPase 8.4
exonuclease VII 8.3
DNA polymerase 8.2
deoxyribonuclease 8.1
lambda exonuclease 8.1
exonuclease V 8.1
CMP-KDO synthetase 8.1
thymidylate kinase 7.9
SAICAR synthetase 7.9
PRE 7.8
exonuclease I 7.7
coproporphyrinogen III oxidase 7.6
Tpt1 7.5
3'-exonuclease 7.4
dUTPase 7.4
endonuclease 7.3
RNase H 6.9
L-serine dehydratase 6.7
DNA methyltransferase 6.5
PARP 6.4
deoxycytidine kinase 6.4
Protein 2 6.3
glycerol dehydratase 6.3
UDP-glucosyltransferase 6.2
lecithin:retinol acyltransferase 6.2
topoisomerase 6.1
dCMP deaminase 6.0
topoisomerase 6.0
guanylate kinase 6.0
CLK1 6.0
deoxyribonuclease 5.9
poly(ADP-ribose) glycohydrolase 5.8
DNase II 5.8
alanyl-tRNA synthetase 5.7
4-hydroxyphenylpyruvate dioxygenase 5.7
venom phosphodiesterase 5.7
formaldehyde dehydrogenase 5.6
S1 nuclease 5.6
peptide deformylase 5.6
DNase 5.5
nucleoside hydrolase 5.4
succinic semialdehyde dehydrogenase 5.3
poly(A) polymerase 5.1
tryptophan synthase 5.1
propionyl-CoA carboxylase 5.1
propionyl-CoA carboxylase 5.1
restriction-modification system 5.0
phosphodiesterase 4.9
ribonucleotide reductase 4.9
ubiquitin-protein ligase 4.9
transaldolase 4.9
succinyl-CoA synthetase 4.8
acyl-CoA synthetase 4.8
PAT 4.8
PHD 4.7
aconitase 4.7
CGT 4.7
more...
Compound
C21H26ClN3O2 13.5
Fagaronine chloride 13.5
Bleomycin B2 12.5
C31H24N4 12.5
Decylubiquinone 11.2
Acranil 11.2
C13H8N2O2 10.9
Potassium acetate 10.2
Nemonapride 9.8
deoxyribose-5-phosphate 9.8
2,2,2-trifluoroacetamide 9.6
O6-Methylguanine 8.9
Deoxyinosine 8.8
HECNU 8.7
7-Methylguanine 8.7
1,10-decanediol 8.7
NMN 8.3
Valyl 8.3
Novex 8.2
Methylazoxymethanol 8.1
PCNU 8.0
3-chloropyridine 7.9
Uracil 7.9
Temozolomide 7.8
BMN 7.7
1,3-dithiolane 7.7
3-aminobenzamide 7.5
Phloroglucinol 7.4
S-methylcysteine 7.4
1,5-pentanediol 7.3
ITG 7.3
Trisodium phosphate 7.3
Tuberin 7.3
Phloroglucinol 7.3
Emtricitabine 7.2
3-methoxybenzamide 7.2
XTP 7.2
propionyl-coenzyme A 7.1
adenylate 7.1
dATP 7.1
Decabromodiphenyl ether 7.0
Thymine 7.0
Trifluorothymidine 7.0
dGTP 7.0
ACNU 7.0
Homoharringtonine 7.0
ethyl bromoacetate 6.9
Deoxyuridine 6.9
Sodium acetate 6.8
dCMP 6.8
TNA 6.7
Plumbagin 6.7
dCTP 6.6
dUDP 6.6
Ethidium bromide 6.6
DPN 6.6
Mesna 6.6
Exotoxin 6.5
methyl methanesulfonate 6.5
SHM 6.5
Usnic acid 6.5
ADP-ribose 6.4
AZQ 6.4
dGMP 6.4
LNT 6.4
1,2,4-benzenetriol 6.3
Vinyl chloride 6.3
Lupeol 6.2
NAD 6.2
NEU 6.2
dUMP 6.2
3-Methyladenine 6.1
NAD 6.1
MNU 6.0
m-AMSA 6.0
BTG 6.0
MNNG 6.0
BTG 6.0
8-quinolinol 6.0
TTP 6.0
more...