Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.5.1.2 (DNA ligase)
2,749 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DNA ligase 1615
DNA repair enzyme 1034
ATP 318
Mol 269
DNA polymerase 249
endonuclease 247
Sep 177
NAD 120
DNA ligase I 119
polynucleotide ligase 99
AMP 98
methylguanine-DNA methyltransferase 88
DNA polymerase beta 75
PARP 73
deoxyribonuclease 72
poly(ADP-ribose) polymerase 69
polypeptide 60
p53 52
hOGG1 50
caspase-3 48
ADP 48
NAD+ 45
proliferating cell nuclear antigen 45
phosphorylating 44
XRCC1 43
thymus 39
DNA ligase III 38
Gen 38
OGG1 38
DNA methyltransferase 37
methyltransferase 37
O6-methylguanine-DNA methyltransferase 37
mer 37
phosphatase 36
NMR 34
photolyase 33
DNA polymerase alpha 33
DNA ligase IV 32
Pol 32
uracil-DNA glycosylase 32
pol 31
fused 30
SDS 29
PARP-1 28
DNA-dependent protein kinase 28
tRNA 27
endonuclease III 27
RNase H 27
phosphodiesterase 26
histone 26
topoisomerase I 26
helicase 25
Pseudomonas 24
superoxide dismutase 24
APE1 24
PARP1 24
AlkB 23
poly (ADP-ribose) polymerase 22
GTP 21
DNA-binding domain 20
Bcl-2 19
ATPase 19
XRCC4 19
BRCA1 18
alkaline phosphatase 17
DNA helicase 17
DNA primase 16
GSH 16
LIG4 15
AP lyase 15
DNA gyrase 14
3'-5' exonuclease 14
zinc finger 14
nucleotide pyrophosphatase 14
cytochrome c 14
SOD 14
DNase I 14
NEIL1 13
catalase 13
DNA polymerase delta 13
more...
Disease
cancer 282
tumor 145
carcinogenesis 60
vaccinia 39
glioblastoma 39
glioma 38
Mycobacterium 31
SDS 29
leukemia 28
breast cancer 28
tuberculosis 26
melanoma 26
carcinoma 20
xeroderma pigmentosum 20
HIV 19
colorectal cancer 17
BLM 17
GSH 16
lung cancer 16
tumorigenesis 15
diabetes 15
ATM 14
cold 14
glioblastoma multiforme 13
hepatocellular carcinoma 13
acute myeloid leukemia 13
plaque 12
immunodeficiency 12
skin cancer 12
African swine fever 11
Haemophilus 11
colon cancer 10
Alzheimer's disease 10
gastric cancer 9
MCF 9
brain tumor 9
neuropathy 9
sarcoma 8
metastases 8
prostate cancer 8
tumor growth 8
Melanoma 7
tumor progression 7
virus infection 7
adenocarcinoma 7
neuroblastoma 7
ischemia 6
herpes simplex 6
neurological disease 6
Epstein 6
lymphoma 6
multiple myeloma 6
Cockayne syndrome 6
ovarian cancer 6
thalassemia 6
Leukemia 6
dementia 6
acute lymphoblastic leukemia 6
anemia 6
hepatitis C 6
oral cancer 5
atherosclerosis 5
XPD 5
tuberous sclerosis 5
bends 5
chronic lymphocytic leukemia 5
WRN 5
adenoma 5
SCID 5
squamous cell carcinoma 5
chronic lymphocytic leukemia 5
non-small cell lung cancer 5
astrocytoma 5
pulmonary fibrosis 4
obesity 4
thrombocytopenia 4
hyperglycemia 4
stroke 4
Mycoplasma 4
SCAN1 4
more...
Symptom
ataxia 15
skin damage 5
hyperoxia 5
erythema 4
starvation 3
collapse 2
acute stress 2
nausea 1
constipation 1
seizures 1
angina 1
fatigue 1
thinning 1
memory loss 1
back pain 1
anesthesia 1
hypothermia 1
functional recovery 1
pain 1
Drug
lysine 41
DNase I 14
Dermatol 13
ROS 13
Gel 12
Asn 11
-deoxyadenosine 11
ampicillin 9
ABC 8
Alanine 6
Mutagen 6
niacin 6
Biopolymers 5
NADH 5
caffeine 4
Arsenic trioxide 4
Etoposide 3
lactose 3
BLM 3
Cardiovasc 3
Adriamycin 3
ascorbate 3
Fragment 2
FAD 2
CTX 2
Glutathione 2
MRC 2
TAT 1
AZT 1
9-THC 1
CDP 1
Dihydro 1
Monit 1
CSF 1
Truvada 1
balanced salt solution 1
Imiquimod 1
Sodium acetate 1
VCR 1
CaCl2 1
Zoledronic acid 1
Methylene blue 1
Domin 1
Fludarabine 1
G418 1
Riboflavin 1
CaCl2 1
CaCl2 1
CED 1
Fotemustine 1
ZnCl2 1
3-Methyladenine 1
IFN-beta 1
Gliadel 1
Monensin 1
Glide 1
BoNT/A 1
Pyridostigmine bromide 1
Docetaxel 1
ZnCl2 1
ICI 1
Oxaliplatin 1
ALA 1
Angiotensin II 1
AraC 1
Tenofovir 1
Adenosine triphosphate 1
TTC 1
Pyridostigmine bromide 1
Doxycycline 1
Orlistat 1
G-CSF 1
Truvada 1
Zoledronic acid 1
Leaf 1
NH3 1
Adozelesin 1
Pronase 1
PMPA 1
Vitamin A 1
more...
Enzyme
DNA ligase 2749
DNA ligase 2746
DNA polymerase 418
endonuclease 247
PARP 99
polynucleotide kinase 71
topoisomerase 57
RNA polymerase 53
topoisomerase 52
phosphodiesterase 50
RNA ligase 42
caspase-3 41
DNA methyltransferase 39
PRE 36
deoxyribonuclease 36
superoxide dismutase 30
DNase 30
protein kinase 28
RNase H 28
Fpg protein 25
ATPase 24
alkaline phosphatase 23
reverse transcriptase 22
endonuclease V 20
RNase 20
RNase 18
catalase 18
AP lyase 17
S1 nuclease 15
trypsin 14
3'-phosphatase 13
ACS 13
endodeoxyribonuclease 12
mitogen-activated protein kinase 12
glutathione peroxidase 11
beta-galactosidase 11
endonuclease VII 10
glutathione S-transferase 9
luciferase 9
alanine aminotransferase 9
thymidine kinase 9
caspase-8 8
ribonucleotide reductase 8
deoxyribonuclease 8
acid phosphatase 7
caspase-9 7
ERK 7
ribonuclease 7
ribonuclease 7
peroxidase 6
dUTPase 6
Escherichia coli exonuclease III 6
xanthine oxidase 6
thymidylate kinase 6
3'-exonuclease 6
micrococcal nuclease 5
focal adhesion kinase 5
ribonucleotide reductase 5
lambda exonuclease 5
deoxycytidine kinase 5
DNase V 4
chloramphenicol acetyltransferase 4
DNA 3'-phosphatase 4
APC 4
caspase-1 4
proteasome 4
AlkA 4
hypoxanthine-guanine phosphoribosyltransferase 4
exonuclease I 4
glucose-6-phosphate dehydrogenase 4
thymidylate synthase 4
thrombin 4
protein kinase C 4
aconitase 4
glyceraldehyde-3-phosphate dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
Protein 2 3
beta-lactamase 3
AMPK 3
transcriptase 3
more...
Compound
DNA 2240
ATP 318
Dec 188
phosphate 176
NAD 167
NAD 120
oxygen 104
AMP 102
pyrimidine 90
pyrimidine 90
adenylate 72
lysine 59
hydrogen 54
ADP 52
nicotinamide 49
ADP 48
ADP 48
sodium 46
ADP-ribose 44
salt 39
alanine 39
water 38
Mg2+ 38
His 38
manganese 35
arginine 35
tyrosine 34
cysteine 32
SDS 31
nitric oxide 30
bromide 28
sulfate 28
zinc 27
iron 27
Asp 26
PEG 26
Clin 25
dATP 24
copper 24
GTP 21
EDTA 20
EDTA 20
methyl methanesulfonate 19
Phe 18
H2O2 17
calcium 17
GSH 17
2-oxoglutarate 17
GSH 17
glucose 16
nitrogen 16
dUTP 16
glycerol 16
PEG 16
Temozolomide 16
TTP 15
ethanol 15
3-aminobenzamide 15
Uracil 15
serine 15
dGTP 15
tryptophan 15
tryptophan 14
silver 14
tryptophan 14
tryptophan 14
threonine 13
potassium 13
dCTP 13
uridine 12
pyrene 12
ACS 11
acetate 11
BCNU 11
urea 11
ACS 11
ammonium 11
NH2 11
aldehyde 10
cobalt 10
more...