Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.5.1.2 (
DNA ligase
)
2,749
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DNA ligase
1615
DNA repair enzyme
1034
ATP
318
Mol
269
DNA polymerase
249
endonuclease
247
Sep
177
NAD
120
DNA ligase I
119
polynucleotide ligase
99
AMP
98
methylguanine-DNA methyltransferase
88
DNA polymerase beta
75
PARP
73
deoxyribonuclease
72
poly(ADP-ribose) polymerase
69
polypeptide
60
p53
52
hOGG1
50
ADP
48
caspase-3
48
proliferating cell nuclear antigen
45
NAD+
45
phosphorylating
44
XRCC1
43
thymus
39
DNA ligase III
38
OGG1
38
Gen
38
O6-methylguanine-DNA methyltransferase
37
DNA methyltransferase
37
mer
37
methyltransferase
37
phosphatase
36
NMR
34
photolyase
33
DNA polymerase alpha
33
Pol
32
DNA ligase IV
32
uracil-DNA glycosylase
32
more...
Disease
cancer
282
tumor
145
carcinogenesis
60
glioblastoma
39
vaccinia
39
glioma
38
Mycobacterium
31
SDS
29
breast cancer
28
leukemia
28
melanoma
26
tuberculosis
26
carcinoma
20
xeroderma pigmentosum
20
HIV
19
BLM
17
colorectal cancer
17
GSH
16
lung cancer
16
diabetes
15
tumorigenesis
15
ATM
14
cold
14
acute myeloid leukemia
13
hepatocellular carcinoma
13
glioblastoma multiforme
13
immunodeficiency
12
plaque
12
skin cancer
12
African swine fever
11
Haemophilus
11
Alzheimer's disease
10
colon cancer
10
MCF
9
brain tumor
9
neuropathy
9
gastric cancer
9
tumor growth
8
prostate cancer
8
sarcoma
8
more...
Symptom
ataxia
15
skin damage
5
hyperoxia
5
erythema
4
starvation
3
collapse
2
acute stress
2
nausea
1
constipation
1
seizures
1
angina
1
fatigue
1
thinning
1
memory loss
1
back pain
1
anesthesia
1
hypothermia
1
functional recovery
1
pain
1
Drug
lysine
41
DNase I
14
ROS
13
Dermatol
13
Gel
12
Asn
11
-deoxyadenosine
11
ampicillin
9
ABC
8
niacin
6
Alanine
6
Mutagen
6
Biopolymers
5
NADH
5
Arsenic trioxide
4
caffeine
4
Adriamycin
3
ascorbate
3
BLM
3
Cardiovasc
3
lactose
3
Etoposide
3
MRC
2
Glutathione
2
Fragment
2
FAD
2
CTX
2
ZnCl2
1
Oxaliplatin
1
AZT
1
AraC
1
Dihydro
1
Monit
1
Adenosine triphosphate
1
balanced salt solution
1
VCR
1
CaCl2
1
Zoledronic acid
1
G-CSF
1
Leaf
1
more...
Enzyme
DNA ligase
2749
DNA ligase
2746
DNA polymerase
418
endonuclease
247
PARP
99
polynucleotide kinase
71
topoisomerase
57
RNA polymerase
53
topoisomerase
52
phosphodiesterase
50
RNA ligase
42
caspase-3
41
DNA methyltransferase
39
deoxyribonuclease
36
PRE
36
superoxide dismutase
30
DNase
30
protein kinase
28
RNase H
28
Fpg protein
25
ATPase
24
alkaline phosphatase
23
reverse transcriptase
22
RNase
20
endonuclease V
20
RNase
18
catalase
18
AP lyase
17
S1 nuclease
15
trypsin
14
ACS
13
3'-phosphatase
13
mitogen-activated protein kinase
12
endodeoxyribonuclease
12
beta-galactosidase
11
glutathione peroxidase
11
endonuclease VII
10
luciferase
9
glutathione S-transferase
9
alanine aminotransferase
9
more...
Compound
DNA
2240
ATP
318
Dec
188
phosphate
176
NAD
167
NAD
120
oxygen
104
AMP
102
pyrimidine
90
pyrimidine
90
adenylate
72
lysine
59
hydrogen
54
ADP
52
nicotinamide
49
ADP
48
ADP
48
sodium
46
ADP-ribose
44
salt
39
alanine
39
Mg2+
38
water
38
His
38
manganese
35
arginine
35
tyrosine
34
cysteine
32
SDS
31
nitric oxide
30
bromide
28
sulfate
28
zinc
27
iron
27
PEG
26
Asp
26
Clin
25
dATP
24
copper
24
GTP
21
more...