Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.2 (acetyl-CoA carboxylase)
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Human Gene/Protein
ACACA protein 13.4
docking protein 4 13.4
acetyl-CoA carboxylase 13.4
NSPL1 12.4
mitochondrial glycerol 3-phosphate acyltransferase 12.4
MIG12 12.4
ACC2 12.1
biotin carboxylase 12.0
ACC1 11.9
LIM domain only 3 11.8
ECHDC1 11.8
malonyl-CoA decarboxylase 11.4
CIDEC protein 11.4
zinc finger protein 638 11.4
acetyl-CoA carboxylase 2 11.4
CCDC3 11.1
TSARG7 11.1
armadillo repeat-containing protein 10.8
KRAP 10.8
TBC1D1 protein 10.8
fatty acid synthase 10.8
carnitine palmitoyltransferase 1 10.7
acyl-CoA synthetase short-chain family member 2 10.7
sterol regulatory element-binding protein-1c 10.7
fatty-acid synthase 10.7
propionyl-CoA carboxylase 10.7
Kruppel-like factor 10 10.6
PANK3 10.6
Cx31.9 10.6
stearoyl-CoA desaturase 10.6
sterol regulatory element binding protein-1 10.5
acetyl-CoA carboxylase alpha 10.3
nNOSmu 10.3
ADAP2 10.3
ATP citrate lyase 10.2
carnitine palmitoyltransferase I 10.2
acyl-CoA synthetase long-chain family member 1 10.2
sterol regulatory element-binding protein 10.1
carnitine palmitoyltransferase 10.1
glycerol-3-phosphate dehydrogenase 2 10.0
phosphorylase, glycogen 10.0
CTRP6 9.8
AMP-activated protein kinase 9.8
Hyodeoxycholic acid 9.7
SLC27A3 9.7
ACACB 9.7
P138 9.6
pccA 9.6
fatty acid transport protein 1 9.6
sortilin 1 9.6
SOC3 9.5
NFYC 9.5
AACS 9.5
Malic dehydrogenase 9.5
transcription factor A, mitochondrial 9.5
Pyruvate carboxylase 9.5
holocarboxylase synthetase 9.5
carbohydrate response element binding protein 9.5
Holocarboxylase synthetase 9.5
ACACA 9.3
AMPK1 9.3
phosphoenolpyruvate carboxykinase 1 9.3
SREBP-1 9.3
SREBP-1c 9.2
CPT1 9.2
acetyl-CoA synthetase 9.2
NT5 9.2
CTRP1 9.2
apobec-1 complementation factor 9.2
carnitine palmitoyltransferase 1C 9.2
SREBP-1a 9.1
SAMS 9.1
ACSF3 9.1
carnitine palmitoyltransferase 1A 9.1
CPT1C 9.0
neuroendocrine-specific protein 9.0
TBC1D4 9.0
TBC1D1 9.0
FGFR1OP 9.0
CT A 9.0
more...
Disease
Multiple carboxylase deficiency 10.6
Biotin deficiency 9.8
SAMS 9.2
Fulminant hepatitis 7.9
hypogalactia 7.8
TD2 7.4
SCD 7.2
fatty liver 7.2
FADS 7.1
alcoholic fatty liver 6.9
Biotinidase deficiency 6.7
BDB 6.6
lipid disorder 6.6
Simpson-Golabi-Behmel syndrome 6.6
hypopharyngeal squamous cell carcinoma 6.5
hyperglycinemia 6.3
MCD 6.2
Nonalcoholic fatty liver 6.1
HS3 6.0
AA1 6.0
LPI 5.9
FAS 5.9
LWS 5.8
nagana 5.8
propionic acidemia 5.7
LDLR 5.6
AD1 5.5
hyperlipidemia 5.3
Bateman 5.2
BEN 5.2
ACP 5.1
dyslipidemia 5.0
SDA 5.0
INS 4.9
Sutton 4.9
Crabs 4.9
obesity 4.7
metabolic syndrome 4.7
BCG infection 4.7
RBS 4.7
hyperinsulinemia 4.7
MDI 4.7
marasmus 4.6
metabolic disorder 4.6
CSE 4.6
CUP 4.5
ketosis 4.5
mitochondrial encephalomyopathy 4.4
overnutrition 4.4
diabetic cardiomyopathy 4.3
abdominal obesity 4.3
ovarian dysfunction 4.3
IS1 4.3
MELAS 4.2
McArdle's disease 4.2
PMT 4.2
glucose intolerance 4.2
hyperphagia 4.2
hyperglycemia 4.1
type 2 diabetes 4.1
SPS 4.1
acne vulgaris 4.1
DMT1 4.0
PKS 3.9
erythroblastosis 3.9
TCD 3.9
lipidosis 3.9
Hepatotoxicity 3.9
nephrosis 3.8
sickle cell disease 3.8
AIN 3.8
Benson 3.8
folate deficiency 3.7
SPS 3.7
MAR 3.6
RDA 3.6
diabetic ketoacidosis 3.6
HTS 3.6
HCA 3.6
Autosomal dominant polycystic kidney disease 3.6
more...
Symptom
stomach pain 4.5
POA 4.4
starvation 4.0
hypoproteinemia 3.3
hepatomegaly 2.9
menopausal symptoms 2.8
anorexia 2.3
cachexia 2.0
exhaustion 1.3
hunger 1.0
lethargy 1.0
arthralgia 0.6
collapse 0.2
discomfort -0.0
discomfort -0.1
functional recovery -0.3
fatigue -0.6
hypothermia -0.6
overweight -1.3
vomiting -1.5
anesthesia -1.7
diarrhea -2.4
pain -4.6
Drug
Aicar 12.4
Cassia seed 11.3
Cinnamon bark 8.8
Mevastatin 8.0
Lard 7.7
Saha 7.3
Corn oil 7.2
Tween 40 6.8
Coconut oil 6.8
Clove 6.7
Liposyn 6.6
Sesamol 6.6
Ara-A 6.6
Troglitazone 6.4
Rebamipide 6.2
Monosodium glutamate 6.1
Cilostazol 5.8
NOV 5.7
Emodin 5.5
Ranolazine 5.5
Ranolazine 5.5
Glucagon 5.5
Geranium 5.4
Rosiglitazone 5.4
Pravastatin 5.4
Bezafibrate 5.3
Salicylate 5.3
Emodin 5.3
Myricetin 5.2
Fipronil 5.2
Kenyan 5.1
Fructose 5.1
Orlistat 4.8
Liraglutide 4.7
Lovastatin 4.6
Citric acid 4.4
GHRP 4.3
Phentolamine 4.2
R1881 4.1
DPA 4.1
Glycyrrhiza 4.0
DMI 4.0
Camp 3.9
Glycerol 3.8
CAM 3.7
Adenosine triphosphate 3.6
DEX 3.6
ALA 3.6
Cetuximab 3.5
Ethanol 3.3
DMAP 3.3
Lactose 3.3
citric acid 3.2
Arsenic trioxide 3.1
Pronase 3.1
Asn 2.9
Bortezomib 2.9
Amiloride 2.9
Triclosan 2.8
NADH 2.7
9-THC 2.7
Docetaxel 2.7
EPA 2.6
Amiloride 2.6
lysine 2.5
ROS 2.5
Bifidobacterium 2.5
-deoxyadenosine 2.4
Estrogens 2.3
Fragment 2.3
Ouabain 2.1
pyridoxal phosphate 2.1
Forskolin 2.1
AZT 2.0
ETA 2.0
lactose 2.0
Gel 1.9
Growth hormone 1.9
AZT 1.9
Vitamin A 1.9
more...
Enzyme
acetyl-CoA carboxylase 13.4
[acetyl-CoA carboxylase]-phosphatase 13.4
EC 6.2.1.14 12.4
biotin carboxylase 12.3
geranoyl-CoA carboxylase 11.8
malonyl-CoA decarboxylase 11.4
acyl-[acyl-carrier 11.4
methylcrotonyl-CoA carboxylase 11.2
transcarboxylase 10.8
fatty-acid synthase 10.7
propionyl-CoA carboxylase 10.6
propionyl-CoA carboxylase 10.6
citrate cleavage enzyme 10.4
aspartate N-acetyltransferase 9.8
EC 1.1.1.82 9.7
citrate lyase 9.6
EC 1.1.1.40 9.4
AMP-activated kinase 9.3
AMP-activated protein kinase 9.2
EC 3.1.2.14 9.2
fatty acyl-CoA reductase 9.1
EC 1.1.1.38 9.0
pipecolate oxidase 9.0
diacylglycerol acyltransferase 8.9
acetyl-CoA synthetase 8.9
CPT 8.8
acyl-CoA oxidase 8.8
pyruvate carboxylase 8.8
3-hydroxy-3-methylglutaryl-CoA reductase 8.8
acetyl-CoA hydrolase 8.6
fatty acid elongase 8.4
glycerol 3-phosphate dehydrogenase 8.4
hormone-sensitive lipase 8.3
propionyl-CoA synthetase 8.3
phosphoethanolamine N-methyltransferase 8.2
acetoacetyl-CoA synthetase 8.1
AMPK 8.1
HMG-CoA synthase 8.0
gluconate dehydrogenase 8.0
zeta-carotene desaturase 7.8
FabA 7.8
acyl-CoA synthetase 7.8
glycerophosphate acyltransferase 7.7
2,4-dienoyl-CoA reductase 7.7
6-phosphogluconate dehydrogenase 7.6
6-phosphogluconate dehydrogenase 7.6
enoyl-ACP reductase 7.6
FabF 7.6
enoyl-ACP reductase 7.6
CPT 7.6
MSAS 7.6
acyl-CoA dehydrogenase 7.5
CPT 7.5
acyl-CoA synthetase 7.4
D-dopachrome tautomerase 7.4
biotinidase 7.4
flavone synthase 7.4
condensing enzyme 7.4
acetolactate synthase 7.3
acyl-CoA dehydrogenase 7.3
FabH 7.3
glycogen synthase phosphatase 7.2
lipoprotein lipase 7.2
AMPK 7.2
glucose-6-phosphate dehydrogenase 7.1
acetoacetyl-CoA thiolase 7.1
pyruvate dehydrogenase 7.1
pyruvate dehydrogenase 7.1
oxaloacetate decarboxylase 7.1
phosphoenolpyruvate carboxykinase 7.0
phosphoenolpyruvate carboxykinase 7.0
3-hydroxyacyl-CoA dehydrogenase 7.0
glycerophosphodiester phosphodiesterase 7.0
pyruvate dehydrogenase phosphatase 7.0
acyl-CoA thioesterase 7.0
phosphoenolpyruvate carboxykinase 7.0
glucokinase 6.9
beta-ketoacyl reductase 6.9
CYP8B1 6.9
lactose synthetase 6.9
more...
Compound
Soraphen A 12.3
Ginkgolide C 11.4
malonyl-CoA 11.1
Ginkgolide C 10.5
2-furoic acid 10.1
2,4,5-trimethoxybenzaldehyde 10.1
2-furoic acid 10.0
Hyodeoxycholic acid 10.0
3-HP 9.9
Methylmalonyl-CoA 9.8
3-methylcrotonyl-CoA 9.7
Sinensetin 9.6
Palmitoyl-L-carnitine 9.6
AICA-riboside 9.5
2,5-dichlorobenzoic acid 9.4
2-furoic acid 9.3
MIPC 9.3
6-MSA 9.1
2,4-dichlorobenzoic acid 9.1
acetyl-CoA 9.1
Methylcitric acid 9.0
AICAR 8.9
Ginkgolic acid 8.8
2-octynoic acid 8.8
Glyceollin 8.7
Glyceollin 8.7
Xylobiose 8.6
Stearoyl-CoA 8.5
Cafestol 8.4
Wedelolactone 8.4
Fucosterol 8.3
Phloroglucinol 8.3
Fucosterol 8.3
AICAR 8.3
Sinigrin 8.2
Oil Red O 8.2
Phloroglucinol 8.2
Deoxypodophyllotoxin 8.1
Pinocembrin 8.1
Aucubin 8.1
Phenylpyruvate 8.0
Dibenzoylmethane 8.0
3-methyl-2-oxopentanoate 8.0
Biotin 8.0
Thujone 7.9
Oil Red O 7.9
Cerulenin 7.9
L-methylmalonyl-CoA 7.9
Pantethine 7.9
[6]-Gingerol 7.8
hexadecanedioic acid 7.8
palmitoyl-CoA 7.8
3-Hydroxypropionic acid 7.8
CPT 7.6
p-Coumaric acid 7.6
1-tetradecanol 7.5
CPT 7.5
Fucoxanthin 7.5
Catalpol 7.4
4-phenylbutanoic acid 7.3
CoA 7.3
Benzbromarone 7.3
butyryl-CoA 7.2
linoleoyl-CoA 7.2
ML-236B 7.2
Triton WR-1339 7.2
Palmitoleic acid 7.1
FK520 7.1
propionyl-coenzyme A 7.0
Punicalagin 7.0
2-ethylhexanoic acid 7.0
2-ethylhexanoic acid 7.0
HMG-CoA 6.9
Nobiletin 6.9
Pterostilbene 6.9
2-tridecanone 6.9
2-ethylhexanoic acid 6.9
Benzyl isothiocyanate 6.9
Triiodothyronine 6.9
2-tridecanone 6.9
more...