Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.2 (acetyl-CoA carboxylase)
2,876 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acetyl-CoA carboxylase 2703
fatty acid synthase 637
AMP-activated protein kinase 604
insulin 577
ATP 267
Sep 195
AMP 180
Mol 180
peroxisome proliferator-activated receptor 156
AMPK 145
stearoyl-CoA desaturase 144
ACC 121
carnitine palmitoyltransferase 120
sterol regulatory element-binding protein 111
leptin 105
biotin carboxylase 103
ACC1 94
lipoprotein lipase 92
glucose-6-phosphate dehydrogenase 86
ACL 76
epididymal 71
reductase 70
adiponectin 68
mTOR 64
HMG-CoA reductase 64
hormone-sensitive lipase 63
peroxisome proliferator-activated receptor gamma 62
SREBP-1 58
pyruvate carboxylase 58
glucagon 57
ACC2 55
CPT 55
NADPH 51
LKB1 50
phosphatase 50
carnitine palmitoyltransferase 1 48
propionyl-CoA carboxylase 46
SREBP-1c 45
carnitine palmitoyltransferase I 45
pyruvate dehydrogenase 43
glycogen synthase 42
pyruvate kinase 42
endoplasmic reticulum 42
polypeptide 40
acyl-CoA oxidase 40
aspartate aminotransferase 39
adipose triglyceride lipase 39
phosphoenolpyruvate carboxykinase 39
ATP citrate lyase 38
sterol regulatory element-binding protein-1c 38
microsomal 38
ADP 38
alanine aminotransferase 38
malonyl-CoA decarboxylase 37
PGC 37
diacylglycerol acyltransferase 36
AICAR 34
protein kinase B 34
PPAR 34
long chain 34
TNF 33
tumor necrosis factor 33
glucokinase 32
CD36 32
superoxide dismutase 31
protein phosphatase 31
C18 31
glucose transporter 31
lipase 30
citrate synthase 28
SREBP-2 27
insulin receptor 27
p38 27
AKT 26
SCD1 26
GLUT4 26
glucose-6-phosphatase 26
CO2 26
6-phosphogluconate dehydrogenase 26
IRS-1 25
more...
Disease
obesity 301
fatty liver 182
diabetes 169
cancer 110
type 2 diabetes 92
tumor 59
hyperlipidemia 58
metabolic syndrome 58
hyperglycemia 47
hepatocellular carcinoma 44
dyslipidemia 41
alcoholic fatty liver 38
cold 30
breast cancer 29
atherosclerosis 26
hyperinsulinemia 25
FAS 22
depression 21
Nonalcoholic fatty liver 21
glucose intolerance 20
SDS 17
tumor growth 16
Mycobacterium 16
sickle cell disease 15
hypertension 15
ischemia 15
SCD 15
cardiovascular disease 15
prostate cancer 13
GSH 13
metabolic disorder 11
MCF 10
tuberculosis 10
hyperphagia 10
ACP 9
tumorigenesis 9
carcinogenesis 8
chronic liver disease 8
lung cancer 7
Alzheimer's disease 7
Brown 7
adenocarcinoma 7
liver disease 7
lipid disorder 7
leukemia 7
plague 7
pancreatic cancer 6
hypoglycemia 6
proteinuria 6
colon cancer 6
hypercholesterolemia 6
carcinoma 5
diabetic nephropathy 5
hepatitis C 5
Blocking 5
ovarian cancer 5
abdominal obesity 5
tumor progression 5
B-cell lymphoma 5
glioma 5
LDLR 5
HIV 5
stroke 5
Biotin deficiency 5
MCD 4
acne vulgaris 4
sepsis 4
ketosis 4
hypothyroidism 4
mole 4
pheochromocytoma 4
mole 4
glioblastoma multiforme 4
melanoma 4
SAMS 4
sepsis 4
PCC 4
myocardial ischemia 4
cirrhosis 4
INS 4
more...
Symptom
starvation 37
anorexia 6
hepatomegaly 4
fatigue 3
collapse 3
exhaustion 3
anesthesia 3
discomfort 2
discomfort 2
cachexia 2
hypoproteinemia 1
overweight 1
POA 1
hypothermia 1
lethargy 1
pain 1
menopausal symptoms 1
stomach pain 1
arthralgia 1
hunger 1
functional recovery 1
diarrhea 1
vomiting 1
Drug
lysine 31
Glucagon 15
NADH 13
Kenyan 11
ROS 10
Dermatol 9
Ethanol 9
Asn 8
citric acid 8
caffeine 7
CAM 7
lactose 6
Fructose 6
Gel 5
EPA 4
Cardiovasc 4
Troglitazone 4
MAP 4
DMI 3
Pravastatin 3
Bifidobacterium 3
Rosiglitazone 3
Glycerol 3
Lovastatin 3
ALA 3
Cassia seed 2
Emodin 2
Glycyrrhiza 2
Saha 2
EE2 2
Corn oil 2
Salicylate 2
Tween 40 2
Emodin 2
DPA 2
DNase I 2
Cilostazol 2
vitamin E 2
Phentolamine 2
Indomethacin 2
Triclosan 1
Myricetin 1
Lard 1
AZT 1
Fipronil 1
Ouabain 1
Coconut oil 1
Histamine 1
Ara-A 1
Amiloride 1
NOV 1
Aicar 1
9-THC 1
Growth hormone 1
Liposyn 1
Angiotensin II 1
THF 1
Orlistat 1
Portal 1
R1881 1
Growth hormone 1
Amiloride 1
Lactose 1
Monosodium glutamate 1
FAD 1
Liraglutide 1
Rebamipide 1
-deoxyadenosine 1
Cinnamon bark 1
Arsenic trioxide 1
Adriamycin 1
Mevastatin 1
Adenosine triphosphate 1
Geranium 1
Ranolazine 1
Pronase 1
pyridoxal phosphate 1
GHRP 1
Ranolazine 1
Nephron 1
more...
Enzyme
acetyl-CoA carboxylase 2876
AMP-activated protein kinase 709
protein kinase 257
CPT 189
AMPK 162
AMPK 155
biotin carboxylase 103
glucose-6-phosphate dehydrogenase 98
lipoprotein lipase 92
mitogen-activated protein kinase 80
hormone-sensitive lipase 63
pyruvate carboxylase 61
CPT 56
CPT 55
alanine aminotransferase 53
pyruvate dehydrogenase 52
phosphoenolpyruvate carboxykinase 52
phosphoenolpyruvate carboxykinase 50
phosphoenolpyruvate carboxykinase 50
aspartate aminotransferase 48
propionyl-CoA carboxylase 48
propionyl-CoA carboxylase 47
3-hydroxy-3-methylglutaryl-CoA reductase 44
pyruvate kinase 42
lipase 42
pyruvate dehydrogenase 42
pyruvate dehydrogenase 42
acyl-CoA oxidase 40
calcineurin 40
diacylglycerol acyltransferase 39
malonyl-CoA decarboxylase 37
superoxide dismutase 32
glucokinase 32
citrate synthase 29
phosphofructokinase 28
AMP-activated kinase 26
6-phosphogluconate dehydrogenase 26
6-phosphogluconate dehydrogenase 26
glucose-6-phosphatase 26
ACS 26
acyl-CoA synthetase 25
fatty-acid synthase 23
luciferase 21
acyl-CoA dehydrogenase 20
ATPase 20
citrate lyase 19
ERK 19
acetyl-CoA synthetase 19
methylcrotonyl-CoA carboxylase 19
transcarboxylase 18
phosphorylase 17
protein kinase C 17
malate dehydrogenase 17
catalase 17
lactate dehydrogenase 16
isocitrate dehydrogenase 15
hexokinase 15
glutathione peroxidase 14
caspase-3 14
alkaline phosphatase 14
isocitrate dehydrogenase 13
phosphatidylinositol 3-kinase 13
acyl-CoA synthetase 13
EC 1.1.1.40 13
acyl-CoA dehydrogenase 13
PDK1 12
3-hydroxy-3-methylglutaryl coenzyme A reductase 12
phosphoenolpyruvate carboxylase 12
glycerol-3-phosphate dehydrogenase 11
CaMKII 11
trypsin 11
HMG-CoA synthase 11
citrate cleavage enzyme 10
CYP7A1 10
AST 10
focal adhesion kinase 10
complex I 10
MEK 10
GSK 9
protein phosphatase 2A 9
more...
Compound
glucose 625
malonyl-CoA 373
acetyl-CoA 271
ATP 267
AMP 219
CoA 219
Dec 209
phosphate 138
acetate 118
DNA 106
glycerol 90
water 86
oxygen 80
Insulin 72
adenylate 65
sodium 61
threonine 57
CPT 55
leucine 55
CPT 55
calcium 51
NADPH 51
NADPH 51
ethanol 48
lysine 46
palmitic acid 43
AICAR 41
ADP 39
cAMP 39
Biotin 38
nitrogen 38
ADP 38
ADP 38
CO2 38
palmitic acid 37
Clin 37
methionine 35
AICAR 35
serine 34
TNF 33
Oil Red O 32
Oil Red O 32
sulfate 32
palmitoyl-CoA 32
alanine 30
glutamine 28
arginine 24
Ile 24
NADP 23
SDS 22
galactose 22
acetic acid 21
ammonium 21
Guo 21
NAD 20
Metformin 19
Metformin 19
Mg2+ 18
tyrosine 18
pentose 17
pentose 17
pentose 17
nitric oxide 17
pentose 17
cysteine 17
NAD 16
Resveratrol 16
HMG-CoA 16
CIT 16
urea 15
hydrogen 15
2-furoic acid 15
2-furoic acid 15
2-furoic acid 15
Glucagon 15
Gly 14
PEG 14
salt 13
carbonate 13
NADH 13
more...