Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.4.1.2 (
acetyl-CoA carboxylase
)
2,876
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetyl-CoA carboxylase
2703
fatty acid synthase
637
AMP-activated protein kinase
604
insulin
577
ATP
267
Sep
195
AMP
180
Mol
180
peroxisome proliferator-activated receptor
156
AMPK
145
stearoyl-CoA desaturase
144
ACC
121
carnitine palmitoyltransferase
120
sterol regulatory element-binding protein
111
leptin
105
biotin carboxylase
103
ACC1
94
lipoprotein lipase
92
glucose-6-phosphate dehydrogenase
86
ACL
76
epididymal
71
reductase
70
adiponectin
68
mTOR
64
HMG-CoA reductase
64
hormone-sensitive lipase
63
peroxisome proliferator-activated receptor gamma
62
SREBP-1
58
pyruvate carboxylase
58
glucagon
57
ACC2
55
CPT
55
NADPH
51
LKB1
50
phosphatase
50
carnitine palmitoyltransferase 1
48
propionyl-CoA carboxylase
46
SREBP-1c
45
carnitine palmitoyltransferase I
45
pyruvate dehydrogenase
43
glycogen synthase
42
pyruvate kinase
42
endoplasmic reticulum
42
polypeptide
40
acyl-CoA oxidase
40
aspartate aminotransferase
39
adipose triglyceride lipase
39
phosphoenolpyruvate carboxykinase
39
ATP citrate lyase
38
sterol regulatory element-binding protein-1c
38
microsomal
38
ADP
38
alanine aminotransferase
38
malonyl-CoA decarboxylase
37
PGC
37
diacylglycerol acyltransferase
36
AICAR
34
protein kinase B
34
PPAR
34
long chain
34
TNF
33
tumor necrosis factor
33
glucokinase
32
CD36
32
superoxide dismutase
31
protein phosphatase
31
C18
31
glucose transporter
31
lipase
30
citrate synthase
28
SREBP-2
27
insulin receptor
27
p38
27
AKT
26
SCD1
26
GLUT4
26
glucose-6-phosphatase
26
CO2
26
6-phosphogluconate dehydrogenase
26
IRS-1
25
more...
Disease
obesity
301
fatty liver
182
diabetes
169
cancer
110
type 2 diabetes
92
tumor
59
hyperlipidemia
58
metabolic syndrome
58
hyperglycemia
47
hepatocellular carcinoma
44
dyslipidemia
41
alcoholic fatty liver
38
cold
30
breast cancer
29
atherosclerosis
26
hyperinsulinemia
25
FAS
22
depression
21
Nonalcoholic fatty liver
21
glucose intolerance
20
SDS
17
tumor growth
16
Mycobacterium
16
sickle cell disease
15
hypertension
15
ischemia
15
SCD
15
cardiovascular disease
15
prostate cancer
13
GSH
13
metabolic disorder
11
MCF
10
tuberculosis
10
hyperphagia
10
ACP
9
tumorigenesis
9
carcinogenesis
8
chronic liver disease
8
lung cancer
7
Alzheimer's disease
7
Brown
7
adenocarcinoma
7
liver disease
7
lipid disorder
7
leukemia
7
plague
7
pancreatic cancer
6
hypoglycemia
6
proteinuria
6
colon cancer
6
hypercholesterolemia
6
carcinoma
5
diabetic nephropathy
5
hepatitis C
5
Blocking
5
ovarian cancer
5
abdominal obesity
5
tumor progression
5
B-cell lymphoma
5
glioma
5
LDLR
5
HIV
5
stroke
5
Biotin deficiency
5
MCD
4
acne vulgaris
4
sepsis
4
ketosis
4
hypothyroidism
4
mole
4
pheochromocytoma
4
mole
4
glioblastoma multiforme
4
melanoma
4
SAMS
4
sepsis
4
PCC
4
myocardial ischemia
4
cirrhosis
4
INS
4
more...
Symptom
starvation
37
anorexia
6
hepatomegaly
4
fatigue
3
collapse
3
exhaustion
3
anesthesia
3
discomfort
2
discomfort
2
cachexia
2
hypoproteinemia
1
overweight
1
POA
1
hypothermia
1
lethargy
1
pain
1
menopausal symptoms
1
stomach pain
1
arthralgia
1
hunger
1
functional recovery
1
diarrhea
1
vomiting
1
Drug
lysine
31
Glucagon
15
NADH
13
Kenyan
11
ROS
10
Dermatol
9
Ethanol
9
Asn
8
citric acid
8
caffeine
7
CAM
7
lactose
6
Fructose
6
Gel
5
EPA
4
Cardiovasc
4
Troglitazone
4
MAP
4
DMI
3
Pravastatin
3
Bifidobacterium
3
Rosiglitazone
3
Glycerol
3
Lovastatin
3
ALA
3
Cassia seed
2
Emodin
2
Glycyrrhiza
2
Saha
2
EE2
2
Corn oil
2
Salicylate
2
Tween 40
2
Emodin
2
DPA
2
DNase I
2
Cilostazol
2
vitamin E
2
Phentolamine
2
Indomethacin
2
Triclosan
1
Myricetin
1
Lard
1
AZT
1
Fipronil
1
Ouabain
1
Coconut oil
1
Histamine
1
Ara-A
1
Amiloride
1
NOV
1
Aicar
1
9-THC
1
Growth hormone
1
Liposyn
1
Angiotensin II
1
THF
1
Orlistat
1
Portal
1
R1881
1
Growth hormone
1
Amiloride
1
Lactose
1
Monosodium glutamate
1
FAD
1
Liraglutide
1
Rebamipide
1
-deoxyadenosine
1
Cinnamon bark
1
Arsenic trioxide
1
Adriamycin
1
Mevastatin
1
Adenosine triphosphate
1
Geranium
1
Ranolazine
1
Pronase
1
pyridoxal phosphate
1
GHRP
1
Ranolazine
1
Nephron
1
more...
Enzyme
acetyl-CoA carboxylase
2876
AMP-activated protein kinase
709
protein kinase
257
CPT
189
AMPK
162
AMPK
155
biotin carboxylase
103
glucose-6-phosphate dehydrogenase
98
lipoprotein lipase
92
mitogen-activated protein kinase
80
hormone-sensitive lipase
63
pyruvate carboxylase
61
CPT
56
CPT
55
alanine aminotransferase
53
pyruvate dehydrogenase
52
phosphoenolpyruvate carboxykinase
52
phosphoenolpyruvate carboxykinase
50
phosphoenolpyruvate carboxykinase
50
aspartate aminotransferase
48
propionyl-CoA carboxylase
48
propionyl-CoA carboxylase
47
3-hydroxy-3-methylglutaryl-CoA reductase
44
pyruvate kinase
42
lipase
42
pyruvate dehydrogenase
42
pyruvate dehydrogenase
42
acyl-CoA oxidase
40
calcineurin
40
diacylglycerol acyltransferase
39
malonyl-CoA decarboxylase
37
superoxide dismutase
32
glucokinase
32
citrate synthase
29
phosphofructokinase
28
AMP-activated kinase
26
6-phosphogluconate dehydrogenase
26
6-phosphogluconate dehydrogenase
26
glucose-6-phosphatase
26
ACS
26
acyl-CoA synthetase
25
fatty-acid synthase
23
luciferase
21
acyl-CoA dehydrogenase
20
ATPase
20
citrate lyase
19
ERK
19
acetyl-CoA synthetase
19
methylcrotonyl-CoA carboxylase
19
transcarboxylase
18
phosphorylase
17
protein kinase C
17
malate dehydrogenase
17
catalase
17
lactate dehydrogenase
16
isocitrate dehydrogenase
15
hexokinase
15
glutathione peroxidase
14
caspase-3
14
alkaline phosphatase
14
isocitrate dehydrogenase
13
phosphatidylinositol 3-kinase
13
acyl-CoA synthetase
13
EC 1.1.1.40
13
acyl-CoA dehydrogenase
13
PDK1
12
3-hydroxy-3-methylglutaryl coenzyme A reductase
12
phosphoenolpyruvate carboxylase
12
glycerol-3-phosphate dehydrogenase
11
CaMKII
11
trypsin
11
HMG-CoA synthase
11
citrate cleavage enzyme
10
CYP7A1
10
AST
10
focal adhesion kinase
10
complex I
10
MEK
10
GSK
9
protein phosphatase 2A
9
more...
Compound
glucose
625
malonyl-CoA
373
acetyl-CoA
271
ATP
267
AMP
219
CoA
219
Dec
209
phosphate
138
acetate
118
DNA
106
glycerol
90
water
86
oxygen
80
Insulin
72
adenylate
65
sodium
61
threonine
57
CPT
55
leucine
55
CPT
55
calcium
51
NADPH
51
NADPH
51
ethanol
48
lysine
46
palmitic acid
43
AICAR
41
ADP
39
cAMP
39
Biotin
38
nitrogen
38
ADP
38
ADP
38
CO2
38
palmitic acid
37
Clin
37
methionine
35
AICAR
35
serine
34
TNF
33
Oil Red O
32
Oil Red O
32
sulfate
32
palmitoyl-CoA
32
alanine
30
glutamine
28
arginine
24
Ile
24
NADP
23
SDS
22
galactose
22
acetic acid
21
ammonium
21
Guo
21
NAD
20
Metformin
19
Metformin
19
Mg2+
18
tyrosine
18
pentose
17
pentose
17
pentose
17
nitric oxide
17
pentose
17
cysteine
17
NAD
16
Resveratrol
16
HMG-CoA
16
CIT
16
urea
15
hydrogen
15
2-furoic acid
15
2-furoic acid
15
2-furoic acid
15
Glucagon
15
Gly
14
PEG
14
salt
13
carbonate
13
NADH
13
more...