Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.4.1.2 (
acetyl-CoA carboxylase
)
2,876
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetyl-CoA carboxylase
2703
fatty acid synthase
637
AMP-activated protein kinase
604
insulin
577
ATP
267
Sep
195
AMP
180
Mol
180
peroxisome proliferator-activated receptor
156
AMPK
145
stearoyl-CoA desaturase
144
ACC
121
carnitine palmitoyltransferase
120
sterol regulatory element-binding protein
111
leptin
105
biotin carboxylase
103
ACC1
94
lipoprotein lipase
92
glucose-6-phosphate dehydrogenase
86
ACL
76
epididymal
71
reductase
70
adiponectin
68
mTOR
64
HMG-CoA reductase
64
hormone-sensitive lipase
63
peroxisome proliferator-activated receptor gamma
62
pyruvate carboxylase
58
SREBP-1
58
glucagon
57
ACC2
55
CPT
55
NADPH
51
LKB1
50
phosphatase
50
carnitine palmitoyltransferase 1
48
propionyl-CoA carboxylase
46
SREBP-1c
45
carnitine palmitoyltransferase I
45
pyruvate dehydrogenase
43
more...
Disease
obesity
301
fatty liver
182
diabetes
169
cancer
110
type 2 diabetes
92
tumor
59
metabolic syndrome
58
hyperlipidemia
58
hyperglycemia
47
hepatocellular carcinoma
44
dyslipidemia
41
alcoholic fatty liver
38
cold
30
breast cancer
29
atherosclerosis
26
hyperinsulinemia
25
FAS
22
depression
21
Nonalcoholic fatty liver
21
glucose intolerance
20
SDS
17
Mycobacterium
16
tumor growth
16
sickle cell disease
15
ischemia
15
cardiovascular disease
15
SCD
15
hypertension
15
GSH
13
prostate cancer
13
metabolic disorder
11
MCF
10
hyperphagia
10
tuberculosis
10
tumorigenesis
9
ACP
9
carcinogenesis
8
chronic liver disease
8
adenocarcinoma
7
Alzheimer's disease
7
more...
Symptom
starvation
37
anorexia
6
hepatomegaly
4
fatigue
3
collapse
3
exhaustion
3
anesthesia
3
discomfort
2
discomfort
2
cachexia
2
hypoproteinemia
1
overweight
1
POA
1
hypothermia
1
lethargy
1
pain
1
menopausal symptoms
1
stomach pain
1
arthralgia
1
hunger
1
functional recovery
1
diarrhea
1
vomiting
1
Drug
lysine
31
Glucagon
15
NADH
13
Kenyan
11
ROS
10
Ethanol
9
Dermatol
9
Asn
8
citric acid
8
CAM
7
caffeine
7
Fructose
6
lactose
6
Gel
5
MAP
4
EPA
4
Cardiovasc
4
Troglitazone
4
Bifidobacterium
3
Pravastatin
3
Rosiglitazone
3
DMI
3
Lovastatin
3
Glycerol
3
ALA
3
Tween 40
2
EE2
2
vitamin E
2
Cassia seed
2
Emodin
2
Saha
2
DNase I
2
Corn oil
2
DPA
2
Salicylate
2
Cilostazol
2
Glycyrrhiza
2
Emodin
2
Phentolamine
2
Indomethacin
2
more...
Enzyme
acetyl-CoA carboxylase
2876
AMP-activated protein kinase
709
protein kinase
257
CPT
189
AMPK
162
AMPK
155
biotin carboxylase
103
glucose-6-phosphate dehydrogenase
98
lipoprotein lipase
92
mitogen-activated protein kinase
80
hormone-sensitive lipase
63
pyruvate carboxylase
61
CPT
56
CPT
55
alanine aminotransferase
53
phosphoenolpyruvate carboxykinase
52
pyruvate dehydrogenase
52
phosphoenolpyruvate carboxykinase
50
phosphoenolpyruvate carboxykinase
50
propionyl-CoA carboxylase
48
aspartate aminotransferase
48
propionyl-CoA carboxylase
47
3-hydroxy-3-methylglutaryl-CoA reductase
44
lipase
42
pyruvate dehydrogenase
42
pyruvate dehydrogenase
42
pyruvate kinase
42
acyl-CoA oxidase
40
calcineurin
40
diacylglycerol acyltransferase
39
malonyl-CoA decarboxylase
37
superoxide dismutase
32
glucokinase
32
citrate synthase
29
phosphofructokinase
28
glucose-6-phosphatase
26
6-phosphogluconate dehydrogenase
26
AMP-activated kinase
26
6-phosphogluconate dehydrogenase
26
ACS
26
more...
Compound
glucose
625
malonyl-CoA
373
acetyl-CoA
271
ATP
267
AMP
219
CoA
219
Dec
209
phosphate
138
acetate
118
DNA
106
glycerol
90
water
86
oxygen
80
Insulin
72
adenylate
65
sodium
61
threonine
57
CPT
55
CPT
55
leucine
55
NADPH
51
NADPH
51
calcium
51
ethanol
48
lysine
46
palmitic acid
43
AICAR
41
cAMP
39
ADP
39
Biotin
38
nitrogen
38
CO2
38
ADP
38
ADP
38
palmitic acid
37
Clin
37
methionine
35
AICAR
35
serine
34
TNF
33
more...