Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.2 (acetyl-CoA carboxylase)
2,876 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acetyl-CoA carboxylase 2703
fatty acid synthase 637
AMP-activated protein kinase 604
insulin 577
ATP 267
Sep 195
AMP 180
Mol 180
peroxisome proliferator-activated receptor 156
AMPK 145
stearoyl-CoA desaturase 144
ACC 121
carnitine palmitoyltransferase 120
sterol regulatory element-binding protein 111
leptin 105
biotin carboxylase 103
ACC1 94
lipoprotein lipase 92
glucose-6-phosphate dehydrogenase 86
ACL 76
epididymal 71
reductase 70
adiponectin 68
mTOR 64
HMG-CoA reductase 64
hormone-sensitive lipase 63
peroxisome proliferator-activated receptor gamma 62
pyruvate carboxylase 58
SREBP-1 58
glucagon 57
ACC2 55
CPT 55
NADPH 51
LKB1 50
phosphatase 50
carnitine palmitoyltransferase 1 48
propionyl-CoA carboxylase 46
SREBP-1c 45
carnitine palmitoyltransferase I 45
pyruvate dehydrogenase 43
more...
Disease
obesity 301
fatty liver 182
diabetes 169
cancer 110
type 2 diabetes 92
tumor 59
metabolic syndrome 58
hyperlipidemia 58
hyperglycemia 47
hepatocellular carcinoma 44
dyslipidemia 41
alcoholic fatty liver 38
cold 30
breast cancer 29
atherosclerosis 26
hyperinsulinemia 25
FAS 22
depression 21
Nonalcoholic fatty liver 21
glucose intolerance 20
SDS 17
Mycobacterium 16
tumor growth 16
sickle cell disease 15
ischemia 15
cardiovascular disease 15
SCD 15
hypertension 15
GSH 13
prostate cancer 13
metabolic disorder 11
MCF 10
hyperphagia 10
tuberculosis 10
tumorigenesis 9
ACP 9
carcinogenesis 8
chronic liver disease 8
adenocarcinoma 7
Alzheimer's disease 7
more...
Symptom
starvation 37
anorexia 6
hepatomegaly 4
fatigue 3
collapse 3
exhaustion 3
anesthesia 3
discomfort 2
discomfort 2
cachexia 2
hypoproteinemia 1
overweight 1
POA 1
hypothermia 1
lethargy 1
pain 1
menopausal symptoms 1
stomach pain 1
arthralgia 1
hunger 1
functional recovery 1
diarrhea 1
vomiting 1
Drug
lysine 31
Glucagon 15
NADH 13
Kenyan 11
ROS 10
Ethanol 9
Dermatol 9
Asn 8
citric acid 8
CAM 7
caffeine 7
Fructose 6
lactose 6
Gel 5
MAP 4
EPA 4
Cardiovasc 4
Troglitazone 4
Bifidobacterium 3
Pravastatin 3
Rosiglitazone 3
DMI 3
Lovastatin 3
Glycerol 3
ALA 3
Tween 40 2
EE2 2
vitamin E 2
Cassia seed 2
Emodin 2
Saha 2
DNase I 2
Corn oil 2
DPA 2
Salicylate 2
Cilostazol 2
Glycyrrhiza 2
Emodin 2
Phentolamine 2
Indomethacin 2
more...
Enzyme
acetyl-CoA carboxylase 2876
AMP-activated protein kinase 709
protein kinase 257
CPT 189
AMPK 162
AMPK 155
biotin carboxylase 103
glucose-6-phosphate dehydrogenase 98
lipoprotein lipase 92
mitogen-activated protein kinase 80
hormone-sensitive lipase 63
pyruvate carboxylase 61
CPT 56
CPT 55
alanine aminotransferase 53
phosphoenolpyruvate carboxykinase 52
pyruvate dehydrogenase 52
phosphoenolpyruvate carboxykinase 50
phosphoenolpyruvate carboxykinase 50
propionyl-CoA carboxylase 48
aspartate aminotransferase 48
propionyl-CoA carboxylase 47
3-hydroxy-3-methylglutaryl-CoA reductase 44
lipase 42
pyruvate dehydrogenase 42
pyruvate dehydrogenase 42
pyruvate kinase 42
acyl-CoA oxidase 40
calcineurin 40
diacylglycerol acyltransferase 39
malonyl-CoA decarboxylase 37
superoxide dismutase 32
glucokinase 32
citrate synthase 29
phosphofructokinase 28
glucose-6-phosphatase 26
6-phosphogluconate dehydrogenase 26
AMP-activated kinase 26
6-phosphogluconate dehydrogenase 26
ACS 26
more...
Compound
glucose 625
malonyl-CoA 373
acetyl-CoA 271
ATP 267
AMP 219
CoA 219
Dec 209
phosphate 138
acetate 118
DNA 106
glycerol 90
water 86
oxygen 80
Insulin 72
adenylate 65
sodium 61
threonine 57
CPT 55
CPT 55
leucine 55
NADPH 51
NADPH 51
calcium 51
ethanol 48
lysine 46
palmitic acid 43
AICAR 41
cAMP 39
ADP 39
Biotin 38
nitrogen 38
CO2 38
ADP 38
ADP 38
palmitic acid 37
Clin 37
methionine 35
AICAR 35
serine 34
TNF 33
more...