Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.2 (acetyl-CoA carboxylase)
 2,876 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acetyl-CoA carboxylase 2703
fatty acid synthase 637
AMP-activated protein kinase 604
insulin 577
ATP 267
Sep 195
AMP 180
Mol 180
peroxisome proliferator-activated receptor 156
AMPK 145
stearoyl-CoA desaturase 144
ACC 121
carnitine palmitoyltransferase 120
sterol regulatory element-binding protein 111
leptin 105
biotin carboxylase 103
ACC1 94
lipoprotein lipase 92
glucose-6-phosphate dehydrogenase 86
ACL 76
epididymal 71
reductase 70
adiponectin 68
mTOR 64
HMG-CoA reductase 64
hormone-sensitive lipase 63
peroxisome proliferator-activated receptor gamma 62
pyruvate carboxylase 58
SREBP-1 58
glucagon 57
ACC2 55
CPT 55
NADPH 51
LKB1 50
phosphatase 50
carnitine palmitoyltransferase 1 48
propionyl-CoA carboxylase 46
carnitine palmitoyltransferase I 45
SREBP-1c 45
pyruvate dehydrogenase 43
pyruvate kinase 42
glycogen synthase 42
endoplasmic reticulum 42
polypeptide 40
acyl-CoA oxidase 40
phosphoenolpyruvate carboxykinase 39
adipose triglyceride lipase 39
aspartate aminotransferase 39
alanine aminotransferase 38
ATP citrate lyase 38
ADP 38
sterol regulatory element-binding protein-1c 38
microsomal 38
malonyl-CoA decarboxylase 37
PGC 37
diacylglycerol acyltransferase 36
long chain 34
protein kinase B 34
AICAR 34
PPAR 34
TNF 33
tumor necrosis factor 33
CD36 32
glucokinase 32
superoxide dismutase 31
glucose transporter 31
C18 31
protein phosphatase 31
lipase 30
citrate synthase 28
insulin receptor 27
p38 27
SREBP-2 27
glucose-6-phosphatase 26
AKT 26
6-phosphogluconate dehydrogenase 26
CO2 26
GLUT4 26
SCD1 26
IRS-1 25
phosphofructokinase 25
IL-6 24
acetyl-CoA synthetase 23
fatty acid binding protein 23
p53 22
Pyruvate carboxylase 22
FAS 22
sterol regulatory element binding protein-1 22
peroxisome proliferator-activated receptor alpha 21
calmodulin 20
Adiponectin 20
glucose transporter 4 20
fatty-acid synthase 20
NMR 20
EBP 20
casein 20
ATPase 20
ERK1 19
SIRT1 19
cytokine 19
JNK 19
MAPK 19
caspase-3 18
HDL 18
ribosomal protein S6 18
CPT1 18
Leptin 17
SDS 17
sirtuin 1 17
aP2 17
lipopolysaccharide 17
NADP 17
Met 17
cAMP-dependent protein kinase 17
peroxisome proliferator activated receptor 17
interleukin-6 16
perilipin 16
lactate dehydrogenase 16
ANA 16
NAD 16
SCD 15
catalase 15
growth hormone 15
prolactin 15
gut 15
hexokinase 15
ghrelin 15
UCP3 15
Fatty acid synthase 15
albumin 14
alkaline phosphatase 14
p21 14
glutathione peroxidase 14
uncoupling protein 1 14
UCP2 14
malate dehydrogenase 14
PI3K 14
acyl-CoA dehydrogenase 13
isocitrate dehydrogenase 13
microsomal triglyceride transfer protein 13
serum albumin 13
NADH 13
acyl-CoA synthetase 13
acetyl-CoA carboxylase 2 13
phosphatidylinositol 3-kinase 13
threonine 13
ERK 13
GSH 13
histone 12
CPT I 12
phosphoenolpyruvate carboxylase 12
thyroid hormone 12
neuropeptide Y 12
apolipoprotein 12
cyclooxygenase-2 12
Pseudomonas 12
SOD 12
FASN 11
adipokine 11
STO 11
more...
Disease
obesity 301
fatty liver 182
diabetes 169
cancer 110
type 2 diabetes 92
tumor 59
hyperlipidemia 58
metabolic syndrome 58
hyperglycemia 47
hepatocellular carcinoma 44
dyslipidemia 41
alcoholic fatty liver 38
cold 30
breast cancer 29
atherosclerosis 26
hyperinsulinemia 25
FAS 22
depression 21
Nonalcoholic fatty liver 21
glucose intolerance 20
SDS 17
tumor growth 16
Mycobacterium 16
cardiovascular disease 15
hypertension 15
sickle cell disease 15
ischemia 15
SCD 15
GSH 13
prostate cancer 13
metabolic disorder 11
tuberculosis 10
MCF 10
hyperphagia 10
tumorigenesis 9
ACP 9
carcinogenesis 8
chronic liver disease 8
Brown 7
lung cancer 7
leukemia 7
adenocarcinoma 7
liver disease 7
lipid disorder 7
plague 7
Alzheimer's disease 7
hypercholesterolemia 6
colon cancer 6
proteinuria 6
hypoglycemia 6
pancreatic cancer 6
hepatitis C 5
Biotin deficiency 5
diabetic nephropathy 5
ovarian cancer 5
LDLR 5
abdominal obesity 5
carcinoma 5
Blocking 5
B-cell lymphoma 5
tumor progression 5
HIV 5
glioma 5
stroke 5
sepsis 4
acne vulgaris 4
SAMS 4
glioblastoma multiforme 4
mole 4
cardiomyopathy 4
heart failure 4
mole 4
ketosis 4
MCD 4
sepsis 4
myocardial ischemia 4
cirrhosis 4
melanoma 4
pheochromocytoma 4
renal cell carcinoma 4
hypothyroidism 4
PCC 4
INS 4
infectious diseases 3
type 1 diabetes 3
thymoma 3
diabetic ketoacidosis 3
osteoporosis 3
hepatitis 3
chronic disease 3
coronary heart disease 3
Evans 3
brain tumor 3
heart disease 3
Placenta 3
renal disease 3
schizophrenia 3
plaque 3
gestational diabetes mellitus 3
NAME 3
glomerulosclerosis 3
diabetic cardiomyopathy 3
hyperthyroidism 3
lymphoma 3
Graves' disease 3
malaria 3
vaccinia 3
Pineal 3
malnutrition 3
lipodystrophy 2
gastritis 2
Simpson-Golabi-Behmel syndrome 2
fits 2
colorectal cancer 2
epilepsy 2
coronary artery disease 2
immunodeficiency 2
African trypanosomiasis 2
hepatitis B 2
Fulminant hepatitis 2
AIN 2
MDI 2
cognitive impairment 2
skin cancer 2
mastitis 2
HPA 2
cholera 2
polycystic kidney 2
nephrosis 2
acne 2
Newcastle disease 2
chronic renal failure 2
neuroblastoma 2
lung carcinoma 2
pertussis 2
gastric ulcer 2
folate deficiency 2
myeloid leukemia 2
PHA 2
aggressiveness 2
virus infection 2
head and neck cancer 2
propionic acidemia 2
MLC 2
vascular disease 2
tuberous sclerosis 2
polycystic ovary syndrome 2
Adenovirus 2
gestational trophoblastic disease 2
phenylketonuria 2
retinoblastoma 2
lactic acidosis 2
overnutrition 2
osteoarthritis 2
cerebral ischemia 2
Infection 2
infertility 2
alcoholism 2
prediabetes 2
epididymis 2
more...
Symptom
starvation 37
anorexia 6
hepatomegaly 4
fatigue 3
collapse 3
exhaustion 3
anesthesia 3
discomfort 2
discomfort 2
cachexia 2
hypoproteinemia 1
overweight 1
POA 1
hypothermia 1
lethargy 1
pain 1
menopausal symptoms 1
stomach pain 1
arthralgia 1
hunger 1
functional recovery 1
diarrhea 1
vomiting 1
Drug
lysine 31
Glucagon 15
NADH 13
Kenyan 11
ROS 10
Ethanol 9
Dermatol 9
citric acid 8
Asn 8
CAM 7
caffeine 7
Fructose 6
lactose 6
Gel 5
Troglitazone 4
Cardiovasc 4
EPA 4
MAP 4
Glycerol 3
DMI 3
ALA 3
Rosiglitazone 3
Bifidobacterium 3
Lovastatin 3
Pravastatin 3
Emodin 2
Cassia seed 2
Tween 40 2
Emodin 2
Saha 2
EE2 2
vitamin E 2
Corn oil 2
Salicylate 2
Cilostazol 2
Glycyrrhiza 2
DPA 2
DNase I 2
Phentolamine 2
Indomethacin 2
Triclosan 1
Myricetin 1
Lard 1
AZT 1
Fipronil 1
Ouabain 1
Coconut oil 1
Histamine 1
Ara-A 1
Amiloride 1
NOV 1
Aicar 1
9-THC 1
Growth hormone 1
Liposyn 1
Angiotensin II 1
Citric acid 1
Portal 1
THF 1
Orlistat 1
AZT 1
Forskolin 1
Monosodium glutamate 1
FAD 1
Liraglutide 1
Clove 1
R1881 1
Growth hormone 1
Amiloride 1
Lactose 1
Camp 1
Cinnamon bark 1
Arsenic trioxide 1
Geranium 1
Bortezomib 1
-deoxyadenosine 1
DMAP 1
Sesamol 1
Adriamycin 1
Mevastatin 1
Adenosine triphosphate 1
Fragment 1
Ranolazine 1
Pronase 1
pyridoxal phosphate 1
GHRP 1
nitroglycerin 1
Ranolazine 1
Nephron 1
Bezafibrate 1
Cetuximab 1
Rebamipide 1
MRC 1
Docetaxel 1
DEX 1
ETA 1
IL-2 1
Estrogens 1
Vitamin A 1
Monit 1
Enzyme
acetyl-CoA carboxylase 2876
AMP-activated protein kinase 709
protein kinase 257
CPT 189
AMPK 162
AMPK 155
biotin carboxylase 103
glucose-6-phosphate dehydrogenase 98
lipoprotein lipase 92
mitogen-activated protein kinase 80
hormone-sensitive lipase 63
pyruvate carboxylase 61
CPT 56
CPT 55
alanine aminotransferase 53
pyruvate dehydrogenase 52
phosphoenolpyruvate carboxykinase 52
phosphoenolpyruvate carboxykinase 50
phosphoenolpyruvate carboxykinase 50
aspartate aminotransferase 48
propionyl-CoA carboxylase 48
propionyl-CoA carboxylase 47
3-hydroxy-3-methylglutaryl-CoA reductase 44
lipase 42
pyruvate kinase 42
pyruvate dehydrogenase 42
pyruvate dehydrogenase 42
calcineurin 40
acyl-CoA oxidase 40
diacylglycerol acyltransferase 39
malonyl-CoA decarboxylase 37
glucokinase 32
superoxide dismutase 32
citrate synthase 29
phosphofructokinase 28
ACS 26
glucose-6-phosphatase 26
AMP-activated kinase 26
6-phosphogluconate dehydrogenase 26
6-phosphogluconate dehydrogenase 26
acyl-CoA synthetase 25
fatty-acid synthase 23
luciferase 21
acyl-CoA dehydrogenase 20
ATPase 20
methylcrotonyl-CoA carboxylase 19
citrate lyase 19
acetyl-CoA synthetase 19
ERK 19
transcarboxylase 18
phosphorylase 17
protein kinase C 17
catalase 17
malate dehydrogenase 17
lactate dehydrogenase 16
hexokinase 15
isocitrate dehydrogenase 15
caspase-3 14
alkaline phosphatase 14
glutathione peroxidase 14
acyl-CoA dehydrogenase 13
phosphatidylinositol 3-kinase 13
acyl-CoA synthetase 13
isocitrate dehydrogenase 13
EC 1.1.1.40 13
3-hydroxy-3-methylglutaryl coenzyme A reductase 12
phosphoenolpyruvate carboxylase 12
PDK1 12
glycerol-3-phosphate dehydrogenase 11
HMG-CoA synthase 11
trypsin 11
CaMKII 11
MEK 10
CYP7A1 10
focal adhesion kinase 10
AST 10
citrate cleavage enzyme 10
complex I 10
protein phosphatase 2A 9
acetolactate synthase 9
glycerol-3-phosphate dehydrogenase 9
peroxidase 9
PARP 9
GSK 9
RNA polymerase 8
reverse transcriptase 8
3-hydroxyacyl-CoA dehydrogenase 8
NO synthase 8
fatty acid elongase 8
succinate dehydrogenase 8
phosphorylase kinase 8
aldehyde dehydrogenase 7
ATP synthase 7
glutathione S-transferase 7
RNase 6
glycerol 3-phosphate dehydrogenase 6
biotinidase 6
RNase 6
PAL 6
glycerophosphate acyltransferase 6
phosphoglucomutase 6
chalcone synthase 6
thrombin 6
renin 5
phosphoinositide 3-kinase 5
fatty acid desaturase 5
carbonic anhydrase 5
ornithine decarboxylase 5
tyrosine aminotransferase 5
aldehyde dehydrogenase 5
ECH 5
glyceraldehyde-3-phosphate dehydrogenase 5
aldehyde dehydrogenase 5
aconitase 5
3-hydroxyacyl-CoA dehydrogenase 5
aldehyde dehydrogenase 5
aldehyde dehydrogenase 5
adenylate kinase 5
adenylate cyclase 4
proteasome 4
condensing enzyme 4
methionine adenosyltransferase 4
MAT 4
LPL 4
NOS 4
creatine kinase 4
acetoacetyl-CoA thiolase 4
adenosine kinase 4
farnesyltransferase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
ADP-glucose pyrophosphorylase 4
geranoyl-CoA carboxylase 4
ACE 4
glyceraldehyde-3-phosphate dehydrogenase 4
urease 4
CPS 4
HCS 4
guanylate cyclase 3
ribonuclease 3
chymotrypsin 3
histidine kinase 3
glutathione synthetase 3
EC 1.1.1.82 3
ribonuclease 3
caspase-9 3
FabH 3
enoyl-ACP reductase 3
transglutaminase 3
enoyl-ACP reductase 3
4CL 3
chalcone isomerase 3
glycine decarboxylase 3
cathepsin B 3
glutamate dehydrogenase 3
PTA 3
glutamate dehydrogenase 3
glutaminase 3
glutamate dehydrogenase 3
more...
Compound
glucose 625
malonyl-CoA 373
acetyl-CoA 271
ATP 267
CoA 219
AMP 219
Dec 209
phosphate 138
acetate 118
DNA 106
glycerol 90
water 86
oxygen 80
Insulin 72
adenylate 65
sodium 61
threonine 57
leucine 55
CPT 55
CPT 55
calcium 51
NADPH 51
NADPH 51
ethanol 48
lysine 46
palmitic acid 43
AICAR 41
cAMP 39
ADP 39
ADP 38
nitrogen 38
CO2 38
ADP 38
Biotin 38
Clin 37
palmitic acid 37
methionine 35
AICAR 35
serine 34
TNF 33
palmitoyl-CoA 32
Oil Red O 32
Oil Red O 32
sulfate 32
alanine 30
glutamine 28
arginine 24
Ile 24
NADP 23
SDS 22
galactose 22
Guo 21
ammonium 21
acetic acid 21
NAD 20
Metformin 19
Metformin 19
Mg2+ 18
tyrosine 18
pentose 17
pentose 17
pentose 17
nitric oxide 17
pentose 17
cysteine 17
NAD 16
HMG-CoA 16
Resveratrol 16
CIT 16
2-furoic acid 15
2-furoic acid 15
urea 15
hydrogen 15
2-furoic acid 15
Glucagon 15
PEG 14
Gly 14
His 13
carbonate 13
GSH 13
salt 13
Phe 13
NADH 13
GSH 13
2-oxoglutarate 12
L-carnitine 12
stearic acid 12
PMA 12
nicotinamide 11
stearic acid 11
isoleucine 11
glutamate 11
glucose-6-phosphate 11
isoleucine 11
NH2 11
cGMP 11
stearic acid 11
proline 9
Adrenal 9
Triton X-100 9
MDA 9
Carnitine 9
3-methylcrotonyl-CoA 9
Asp 9
valine 9
Dexamethasone 9
betaine 8
zinc 8
Triton 8
Cholesterol 8
TCA 8
methanol 8
iron 8
dicarboxylic acid 8
GTP 8
malonic acid 8
DEAE 8
ammonia 8
Glycogen 8
Curcumin 7
N-acetylcysteine 7
butyric acid 7
potassium 7
Sucrose 7
alloxan 7
caffeine 7
phosphocreatine 6
ACS 6
Cardiol 6
Phytol 6
Fructose 6
isocitrate 6
silver 6
STZ 6
Berberine 6
PEG 6
L-T3 6
Estrogen 6
Thyroid 6
Soraphen A 6
ACS 6
Oleic acid 6
Triiodothyronine 6
Phytol 6
FFA 6
HCO 6
Fenofibrate 5
propionic acid 5
Estrogen 5
Glycogen synthase 5
Quercetin 5
propionic acid 5
Coenzyme A 5
Triton WR-1339 5
Yellow 5
nitrate 5
Hematoxylin 5
butyryl-CoA 5
aldehyde 5
Tris 4
more...