Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.2 (acetyl-CoA carboxylase)
 2,876 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pig coronary smooth muscle cells contain a highly active fatty acid beta-oxidation system as well as significant activities of other enzymes involved in lipid metabolism, i.e. palmitoyl-CoA synthetase, glycerophosphate acyl transferase, acetyl-CoA carboxylase and fatty acid synthetase. Purified plasma membranes of pig coronary smooth muscle cells contain stereospecific (-)-[3H]dihydroalprenolol binding sites of high affinity (Kd = 5.4 nM) and characteristic of the beta 1 subtype. They also contain an adenylate cyclase activity which is stimulated by 5'-guanylyl-imidodiphosphate (Gpp(NH)p) and, to a lesser degree, by (-)-isoproterenol.
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PMID:Study in pig coronary smooth muscle cell subcellular fractions of the activity of various enzymes involved in lipid metabolism and of the beta-receptor adenylate cyclase couple. 632 84