Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.1 (pyruvate carboxylase)
 1,516 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
CGI-49 14.4
pyruvate carboxylase 14.4
pyruvate carboxylase, mitochondrial 13.9
SDHC protein 13.4
Pyruvate carboxylase 13.4
succinyl-CoA:3-ketoacid-CoA transferase 12.8
ASCI 12.5
TOP2 beta 12.0
ATP5J2 12.0
propionyl-CoA carboxylase 11.7
acyl-CoA dehydrogenase 9 11.6
biotin carboxylase 11.5
holocarboxylase synthetase 11.5
PEPCK-M 11.5
L-alanine:glyoxylate aminotransferase 11.2
PCK2 11.1
ATPase homolog 11.0
BPC1 11.0
MCCC2 10.8
phosphoenolpyruvate carboxykinase 10.7
CA V 10.7
carboxylating 10.7
ACSS3 10.7
fructose-1,6-bisphosphatase 1 10.6
pccA 10.6
Max-like protein X 10.6
PEPCK-C 10.5
mitochondrial citrate transport protein 10.5
ODPA 10.4
Malic enzyme 10.4
Holocarboxylase synthetase 10.4
phosphoenolpyruvate carboxykinase 2 10.4
carnitine palmitoyltransferase 1A 10.3
PCK1 10.2
D-fructose-1,6-bisphosphate 1-phosphohydrolase 10.2
phosphoenolpyruvate carboxykinase 1 10.2
PDC2 10.1
TALH 10.0
ME3 10.0
LYS5 10.0
more...
Disease
Multiple carboxylase deficiency 12.6
Avian reticuloendotheliosis 12.0
Biotin deficiency 11.8
PC deficiency 11.3
Organic acidemias 11.0
hyperlysinemia 10.9
Ketonemia 10.9
MILS 10.3
MGA3 10.1
Goodall 8.8
encephalomyelopathy 8.7
Hers 8.7
Carcinoma ex pleomorphic adenoma 8.4
disorders of amino acid metabolism 8.1
Leigh syndrome 8.0
Alpers 7.9
PDH deficiency 7.9
Biotinidase deficiency 7.7
citrullinemia 7.7
marijuana abuse 7.6
Ondine's curse 7.6
lactic acidosis 7.6
propionic acidemia 7.6
Ondine's curse 7.6
Reye's syndrome 7.2
methylmalonic acidemia 6.9
Reye 6.9
glutaric aciduria 6.9
kidney hypertrophy 6.7
hepatic porphyria 6.4
Barth syndrome 6.4
GSD I 6.3
mitochondrial encephalomyopathy 6.3
RDP 6.1
ketosis 6.0
Forbes 5.9
BCH 5.8
lipidosis 5.8
Sutton 5.8
Wernicke's encephalopathy 5.7
more...
Symptom
Tissue anoxia 12.0
Spots 5.5
ketonuria 5.2
hypotonia 5.2
lethargy 4.7
consciousness disturbance 4.7
starvation 4.1
incoordination 3.6
tachypnea 3.0
exhaustion 2.9
cerebellar ataxia 2.5
ataxia 2.4
hemiplegia 2.4
dystonia 2.3
myoclonus 2.3
vomiting 2.0
hunger 1.9
hepatomegaly 1.9
spasticity 1.7
seizures 1.7
anorexia 1.6
hypercapnia 1.4
hypothermia 1.3
constipation 1.0
Ill 0.9
agitation 0.8
acidity 0.5
tremor 0.2
respiratory distress 0.1
anesthesia -0.4
dyspnea -0.4
collapse -0.4
abdominal pain -0.6
fatigue -1.3
Drug
Formycin 10.6
p-Chlorophenyl 10.5
Posilac 10.0
Aspartic Acid 9.2
citric acid 7.1
Corn oil 7.1
Pentostam 7.0
Tween 40 6.8
Citric acid 6.4
CDX 6.4
Bezafibrate 6.2
Sodium valproate 6.0
Colombo 6.0
Glucagon 5.9
NADH 5.9
CDX 5.9
Arsenic trioxide 5.6
Glycerol 5.5
Alanine 5.5
Glutamic acid 5.4
Clofibrate 5.2
Fructose 5.0
DMI 4.9
Monensin 4.5
Galactose 4.3
Aloe 4.1
Vitamin B 4.1
Honey 4.0
lysine 4.0
lactose 3.9
FAD 3.5
Ethanol 3.4
G418 3.2
CDP 3.2
pyridoxal phosphate 3.1
Nitric Oxide 3.0
ALA 2.9
MRC 2.6
Gel 2.5
PCB 2.3
more...
Enzyme
pyruvate carboxylase 14.4
EC 4.1.1.40 13.4
methylcrotonyl-CoA carboxylase 12.9
geranoyl-CoA carboxylase 12.4
acylpyruvate hydrolase 12.4
CimA 12.0
biotin carboxylase 11.8
propionyl-CoA carboxylase 11.6
propionyl-CoA carboxylase 11.6
glycerophosphate phosphatase 11.6
transcarboxylase 11.4
diaminopimelate dehydrogenase 10.9
oxaloacetate decarboxylase 10.8
phosphoenolpyruvate carboxykinase 10.5
phosphoenolpyruvate carboxykinase 10.5
phosphoenolpyruvate carboxykinase 10.4
fructose 1,6-bisphosphatase 10.1
phosphoenolpyruvate carboxylase 10.0
pyruvate dehydrogenase 10.0
pyruvate dehydrogenase 10.0
EC 1.1.1.82 10.0
6-phosphogluconate dehydratase 10.0
EC 1.1.1.38 9.9
phosphoenolpyruvate synthase 9.9
biotinidase 9.8
alcohol acetyltransferase 9.7
pyruvate dehydrogenase 9.6
L-asparagine synthetase 9.6
EC 1.1.1.40 9.5
2-oxoglutarate decarboxylase 9.5
methylmalonate-semialdehyde dehydrogenase 9.4
citramalate synthase 9.3
citrate lyase 9.2
nicotinic acid phosphoribosyltransferase 9.2
diaminopimelate decarboxylase 9.1
glucose-6-phosphatase 9.1
isocitrate lyase 9.1
PPDK 9.0
citrate cleavage enzyme 9.0
acetoacetyl-CoA synthetase 9.0
more...
Compound
6-aminotryptophan 14.4
Chlorothricin 13.4
2-hydroxyethyl carbamate 12.0
Decanoylcarnitine 11.8
PYC 11.5
Fluoropyruvate 11.2
O-acetylcarnitine 11.2
Butylmalonate 11.0
N-formimino-l-glutamate 11.0
3-methylcrotonyl-CoA 10.9
2,4-pyrimidinediamine 10.7
Oxamate 10.3
3-hydroxyisovaleric acid 10.1
Phenylpyruvate 10.0
oxalacetate 9.9
beta-methylcrotonic acid 9.8
dimethyl malate 9.8
propionyl-coenzyme A 9.5
Ethoxzolamide 9.5
TPTA 9.3
acetyl-CoA 9.2
Metribuzin 9.0
benzoylformic acid 9.0
dimethyl succinate 8.9
Nialamide 8.8
2-Oxoglutarate 8.8
2-oxobutyrate 8.7
Biotin 8.7
Pyruvate 8.6
2-oxobutyrate 8.4
Amytal 8.3
isocitrate 8.2
Acetyl phosphate 8.2
malic acid 8.1
malic acid 8.1
malic acid 8.1
malic acid 8.1
Pyruvate kinase 7.9
1-Methyl-4-phenylpyridinium 7.9
2-oxoglutarate 7.9
more...