Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.4.1.1 (
pyruvate carboxylase
)
1,516
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
pyruvate carboxylase
1416
phosphoenolpyruvate carboxykinase
239
ATP
191
insulin
179
pyruvate dehydrogenase
171
Pyruvate carboxylase
166
CO2
102
Sep
92
pyruvate kinase
87
NMR
82
glucose-6-phosphatase
77
ADP
74
malate dehydrogenase
71
phosphoenolpyruvate carboxylase
70
TCA
67
citrate synthase
66
NADH
63
glucagon
62
Mol
61
acetyl-CoA carboxylase
59
lactate dehydrogenase
56
NAD
49
propionyl-CoA carboxylase
48
isocitrate dehydrogenase
46
glutamine synthetase
45
glutamate dehydrogenase
42
biotin carboxylase
40
NADPH
40
NADP
36
GABA
35
aspartate aminotransferase
35
phosphatase
34
pyruvate dehydrogenase complex
34
phosphofructokinase
33
AMP
31
polypeptide
28
Pseudomonas
26
hexokinase
26
fumarase
25
glucokinase
23
more...
Disease
diabetes
53
lactic acidosis
39
hypoglycemia
38
cancer
33
type 2 diabetes
29
tumor
28
hyperglycemia
25
fatty liver
21
PC deficiency
20
Leigh syndrome
18
obesity
15
depression
13
Biotin deficiency
11
cold
10
encephalopathy
10
breast cancer
10
SDS
10
Mycobacterium
9
insulinoma
8
epilepsy
8
hepatocellular carcinoma
7
glioma
6
glucose intolerance
6
hepatic encephalopathy
6
Reye's syndrome
6
ischemia
6
ketosis
6
coma
5
sepsis
4
malnutrition
4
stroke
4
pheochromocytoma
4
renal tubular acidosis
4
mole
4
GSH
4
mole
4
mental retardation
4
propionic acidemia
4
metabolic disorder
4
methylmalonic acidemia
4
more...
Symptom
starvation
20
seizures
12
hypotonia
10
lethargy
7
vomiting
6
exhaustion
5
anesthesia
4
ataxia
4
dystonia
2
hypothermia
2
anorexia
2
abdominal pain
1
cerebellar ataxia
1
fatigue
1
consciousness disturbance
1
Ill
1
hunger
1
Spots
1
hypercapnia
1
spasticity
1
respiratory distress
1
tachypnea
1
myoclonus
1
constipation
1
dyspnea
1
agitation
1
Tissue anoxia
1
hepatomegaly
1
acidity
1
collapse
1
ketonuria
1
incoordination
1
hemiplegia
1
tremor
1
Drug
citric acid
66
NADH
64
lysine
44
lactose
12
Glucagon
11
CSF
7
Alanine
6
Glycerol
5
Ethanol
5
ROS
4
Gel
4
DMI
3
Fructose
3
Arsenic trioxide
3
FAD
3
ascorbate
2
Asn
2
Posilac
2
Citric acid
2
vitamin E
1
Formycin
1
ALA
1
Leaf
1
Aloe
1
pyridoxal phosphate
1
Vitamin B
1
CDX
1
Galactose
1
Dermatol
1
THF
1
G418
1
Corn oil
1
Honey
1
CDP
1
Aspartic Acid
1
p-Chlorophenyl
1
MAP
1
Glutamic acid
1
Monensin
1
Nitric Oxide
1
more...
Enzyme
pyruvate carboxylase
1516
phosphoenolpyruvate carboxykinase
296
phosphoenolpyruvate carboxykinase
296
phosphoenolpyruvate carboxykinase
296
pyruvate dehydrogenase
206
pyruvate dehydrogenase
171
pyruvate dehydrogenase
171
pyruvate kinase
90
phosphoenolpyruvate carboxylase
84
glucose-6-phosphatase
81
malate dehydrogenase
75
citrate synthase
71
acetyl-CoA carboxylase
61
lactate dehydrogenase
59
propionyl-CoA carboxylase
52
propionyl-CoA carboxylase
51
isocitrate dehydrogenase
50
isocitrate dehydrogenase
48
glutamine synthetase
45
glutamate dehydrogenase
43
glutamate dehydrogenase
43
glutamate dehydrogenase
43
fructose 1,6-bisphosphatase
42
biotin carboxylase
40
phosphofructokinase
40
aspartate aminotransferase
38
methylcrotonyl-CoA carboxylase
33
hexokinase
27
fumarase
27
alanine aminotransferase
26
alpha-ketoglutarate dehydrogenase
26
succinate dehydrogenase
25
isocitrate lyase
25
glucokinase
24
glucose-6-phosphate dehydrogenase
23
aconitase
19
biotinidase
17
glyceraldehyde-3-phosphate dehydrogenase
16
luciferase
15
transcarboxylase
14
more...
Compound
glucose
632
glutamate
229
ATP
191
glutamine
170
acetyl-CoA
152
alanine
152
phosphate
135
CoA
130
CO2
122
Dec
96
acetate
96
glycerol
83
2-oxoglutarate
82
ADP
75
ADP
74
ADP
74
TCA
70
NAD
68
NADH
64
DNA
54
oxygen
53
pentose
52
pentose
51
pentose
51
pentose
51
NADP
49
NAD
49
urea
48
lysine
46
nitrogen
44
NADPH
40
NADPH
40
ethanol
38
Pyruvate
35
GABA
35
GABA
35
AMP
35
oxalacetate
34
Biotin
33
sodium
33
more...