Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.1 (pyruvate carboxylase)
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Human Gene/Protein
pyruvate carboxylase 14.4
CGI-49 14.4
pyruvate carboxylase, mitochondrial 13.9
SDHC protein 13.4
Pyruvate carboxylase 13.4
succinyl-CoA:3-ketoacid-CoA transferase 12.8
ASCI 12.5
TOP2 beta 12.0
ATP5J2 12.0
propionyl-CoA carboxylase 11.7
acyl-CoA dehydrogenase 9 11.6
biotin carboxylase 11.5
holocarboxylase synthetase 11.5
PEPCK-M 11.5
L-alanine:glyoxylate aminotransferase 11.2
PCK2 11.1
BPC1 11.0
ATPase homolog 11.0
MCCC2 10.8
phosphoenolpyruvate carboxykinase 10.7
CA V 10.7
carboxylating 10.7
ACSS3 10.7
fructose-1,6-bisphosphatase 1 10.6
Max-like protein X 10.6
pccA 10.6
PEPCK-C 10.5
mitochondrial citrate transport protein 10.5
ODPA 10.4
Malic enzyme 10.4
Holocarboxylase synthetase 10.4
phosphoenolpyruvate carboxykinase 2 10.4
carnitine palmitoyltransferase 1A 10.3
PCK1 10.2
D-fructose-1,6-bisphosphate 1-phosphohydrolase 10.2
phosphoenolpyruvate carboxykinase 1 10.2
PDC2 10.1
TALH 10.0
ME3 10.0
LYS5 10.0
phosphoenolpyruvate carboxylase 9.9
MAEA 9.9
glycerol-3-phosphate dehydrogenase 1 9.8
Phosphoserine phosphatase 9.8
ME4 9.8
biotinidase 9.8
fructose 1,6-bisphosphatase 9.8
pyruvate dehydrogenase 9.8
aconitate hydratase 9.8
carbamoylphosphate synthetase I 9.8
steroid dehydrogenase-like protein 9.7
sodium-dependent multivitamin transporter 9.7
CA5 9.6
3-hydroxybutyrate dehydrogenase 9.6
RagD 9.6
SLC25A1 9.6
ubiquinol-cytochrome c reductase complex 9.6
CS-3 9.6
Nicotinamide nucleotide transhydrogenase 9.5
S3-12 9.5
MCCC1 9.5
Fructose 1,6-bisphosphatase 9.5
5-methyltetrahydrofolate-homocysteine methyltransferase 9.5
fumarase 9.4
nicotinic acid phosphoribosyltransferase 9.4
OPA3 9.3
IST1 9.3
Phosphoglycerate dehydrogenase 9.3
acetoacetyl-CoA synthetase 9.2
PEPCK 9.2
phosphoglyceromutase 9.2
PSPH 9.1
arylsulfatase E 9.1
MUL 9.1
decarboxylating 9.1
hepatocyte nuclear factor 1 alpha 9.1
glucose-6-phosphatase 9.0
SP-22 9.0
PGC1A 9.0
2-oxoglutarate dehydrogenase 9.0
SARP 8.9
MDH2 8.9
citrate transport protein 8.9
HMGCS1 8.9
ATP citrate lyase 8.9
Malate dehydrogenase 8.9
PEX10 8.9
Pyruvate dehydrogenase 8.8
acetyl-CoA carboxylase 8.8
ACADVL 8.8
CS-2 8.8
methylmalonate-semialdehyde dehydrogenase 8.8
6-phosphofructokinase 8.8
SSB1 8.8
acetyl-CoA carboxylase 1 8.8
lactate dehydrogenase-A 8.7
ASNS 8.7
PSAT1 8.7
malate dehydrogenase 8.7
pyruvate dehydrogenase complex 8.7
NM23-H2 8.7
Isocitrate dehydrogenase 8.6
AGC1 8.6
oxoglutarate 8.6
LPMC 8.6
isocitric dehydrogenase 8.5
sarcosine dehydrogenase 8.5
G6Pase 8.5
E1 alpha 8.5
CA VII 8.5
NOX3 8.5
Spot14 8.5
NADP-ME 8.5
MDH1 8.5
fructose-1,6-bisphosphatase 8.5
pyruvate kinase 8.5
PHGDH 8.5
EHD2 8.4
alpha-ketoglutarate dehydrogenase 8.4
LeuRS 8.4
GDH2 8.4
isocitrate dehydrogenase 8.4
citrate synthase 8.3
PDK2 8.3
Glycerol kinase 8.3
NADP+-dependent isocitrate dehydrogenase 8.3
USF1 8.3
USF2 8.3
soxB 8.3
monocarboxylate transporter 4 8.3
HMG-CoA lyase 8.3
carbonic anhydrase VI 8.3
PDH 8.3
SLC19A3 8.3
ACC1 8.3
carbamoylphosphate synthetase 8.2
Glucose-6-phosphatase 8.2
H-protein 8.2
ACC2 8.2
acetyl-CoA synthetase 8.2
TCA 8.2
MSUD 8.2
ACSL3 8.1
phosphoserine aminotransferase 8.1
glutamic dehydrogenase 8.1
FSP27 8.1
ME2 8.1
NADP-malic enzyme 8.1
acetyl-CoA carboxylase alpha 8.1
retinoic acid-inducible gene 1 8.1
PCCB 8.1
EGP 8.1
phosphoglucomutase 1 8.1
ATF5 8.1
BCATm 8.1
CA IV 8.0
ADP/ATP translocase 8.0
argininosuccinate synthetase 8.0
mitochondrial carrier protein 8.0
AB3 8.0
NADP-dependent isocitrate dehydrogenase 8.0
SLC2A4 8.0
FBP1 7.9
SP-2 7.9
Pyruvate kinase 7.9
NARP 7.9
SESN2 7.9
HMGCS2 7.9
HXB 7.9
COXI 7.9
hydroxymethylglutaryl-CoA synthase 7.9
pyruvate dehydrogenase kinase 4 7.8
ME1 7.8
betaine-homocysteine methyltransferase 7.8
SLC2A2 7.8
NR1D1 7.8
serine dehydratase 7.8
SCOT 7.7
adenosyltransferase 7.7
glycerokinase 7.7
ACK 7.7
NEFA 7.7
liver glycogen synthase 7.7
INS-1 7.7
mitofilin 7.7
forkhead/winged helix transcription factor 7.7
phosphofructokinase 7.7
glutamate dehydrogenase 7.6
NOR-1 7.6
RPL32 7.6
Fructose-1,6-bisphosphatase 7.6
HMG-CoA synthase 7.6
HAK 7.6
CPT1 7.6
glutamine synthetase 7.6
GCR 7.6
TIP47 7.6
UMP-CMP kinase 7.5
LYS2 7.5
V75 7.5
CAIV 7.5
CA II 7.5
Citrate synthase 7.5
aconitase 7.5
D-lactate dehydrogenase 7.5
PFL 7.5
PK2 7.5
mitofusin 1 7.5
islet-specific glucose-6-phosphatase catalytic subunit-related protein 7.4
glyceraldehyde 3-phosphate dehydrogenase 7.4
glucokinase 7.4
transaldolase 7.4
PEP 7.4
pyruvate dehydrogenase kinase 7.4
acyl-CoA synthetase 7.4
fatty-acid synthase 7.3
cytosolic malate dehydrogenase 7.3
mitochondrial aconitase 7.3
beta-adrenergic receptor kinase 7.3
Carbonic anhydrase 7.2
SLC22A5 7.2
DIO2 7.2
NAD-malic enzyme 7.2
carnitine acetyltransferase 7.2
dihydrodipicolinate synthase 7.2
pyridine nucleotide transhydrogenase 7.2
IDP 7.1
beta-ketothiolase 7.1
hexokinase 1 7.1
Maltase 7.1
glutamate carrier 7.1
MSU 7.1
PDK4 7.1
acyl-CoA dehydrogenase 7.1
D54 7.1
thioredoxin interacting protein 7.1
glutaminase 7.1
ACSL1 7.1
GSTM 7.1
6-phosphogluconate dehydrogenase 7.1
Phosphofructokinase 7.1
tafazzin 7.1
OST1 7.0
phosphate-activated glutaminase 7.0
NAMPT 7.0
pancreatic and duodenal homeobox 1 7.0
SGT1 7.0
NADH2 6.9
carbohydrate response element binding protein 6.9
BCH 6.9
BB1 6.9
long-chain acyl-CoA synthetase 6.9
6PGD 6.9
L-lactate dehydrogenase 6.9
IP3R1 6.9
FBPase 6.8
citrin 6.8
carbonic anhydrase III 6.8
FDH 6.8
NAD kinase 6.8
HKII 6.8
methylenetetrahydrofolate dehydrogenase 6.8
ACL 6.8
lactate dehydrogenase A 6.8
lipoamide dehydrogenase 6.7
delta-aminolevulinate synthase 6.7
alpha polypeptide 6.7
NADP 6.7
GC1 6.7
hexokinase 6.7
carnitine palmitoyltransferase 6.7
Prohibitin 6.7
GPD1 6.7
Aspartate aminotransferase 6.7
NADH-ubiquinone reductase 6.7
microsomal triglyceride transfer protein 6.6
UDPG 6.6
Glutaminase 6.6
succinic semialdehyde dehydrogenase 6.6
GLUT-2 6.6
Glucokinase 6.6
Phosphorylase 6.6
preproinsulin 6.6
CS-1 6.6
galactose-1-phosphate uridyltransferase 6.6
CPT II 6.5
adipophilin 6.5
lipoamide 6.5
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 6.5
TCF3 6.5
glycine decarboxylase 6.5
GC2 6.5
Na+/glucose cotransporter 6.5
long-chain acyl-CoA dehydrogenase 6.4
Nkx6.1 6.4
glycolytic enzyme 6.4
LDH-B 6.4
pantothenate kinase 6.4
ALF 6.3
PTS 6.3
ASCL1 6.3
MDH 6.3
fatty acid synthase 6.3
3-hydroxyacyl-CoA dehydrogenase 6.3
Stearoyl-CoA desaturase 6.3
BMI-1 6.3
TSPY 6.3
GLS 6.2
LDH-X 6.2
fumarylacetoacetate hydrolase 6.2
CDD 6.2
RDP 6.2
glucose dehydrogenase 6.2
ornithine transcarbamylase 6.2
TCB 6.2
PDK 6.2
NAD+ 6.1
isocitrate dehydrogenase 1 6.1
HBA 6.1
prohibitin 6.1
more...
Disease
Multiple carboxylase deficiency 12.6
Avian reticuloendotheliosis 12.0
Biotin deficiency 11.8
PC deficiency 11.3
Organic acidemias 11.0
hyperlysinemia 10.9
Ketonemia 10.9
MILS 10.3
MGA3 10.1
Goodall 8.8
encephalomyelopathy 8.7
Hers 8.7
Carcinoma ex pleomorphic adenoma 8.4
disorders of amino acid metabolism 8.1
Leigh syndrome 8.0
Alpers 7.9
PDH deficiency 7.9
Biotinidase deficiency 7.7
citrullinemia 7.7
Ondine's curse 7.6
marijuana abuse 7.6
lactic acidosis 7.6
propionic acidemia 7.6
Ondine's curse 7.6
Reye's syndrome 7.2
Reye 6.9
methylmalonic acidemia 6.9
glutaric aciduria 6.9
kidney hypertrophy 6.7
hepatic porphyria 6.4
Barth syndrome 6.4
GSD I 6.3
mitochondrial encephalomyopathy 6.3
RDP 6.1
ketosis 6.0
Forbes 5.9
BCH 5.8
lipidosis 5.8
Sutton 5.8
Wernicke's encephalopathy 5.7
PDC 5.7
Benson 5.7
FDH 5.7
marasmus 5.6
insulinoma 5.5
clonorchiasis 5.5
MELAS 5.5
porphyria 5.4
renal tubular acidosis 5.4
profound mental retardation 5.3
mitochondrial myopathy 5.2
laryngospasm 5.2
hypoglycemia 5.2
MELAS 5.2
hyperphenylalaninemia 5.1
hypophosphatasia 5.1
AIP 5.1
MCD 5.1
cystinuria 5.1
GSD 5.1
Korsakoff's syndrome 5.0
AIP 5.0
Kearns-Sayre syndrome 5.0
reticuloendotheliosis 5.0
fatty liver 5.0
GSD 4.9
Acute liver failure 4.9
hepatic encephalopathy 4.9
dysphasia 4.8
PMS 4.7
DWI 4.7
PCT 4.7
kwashiorkor 4.7
parakeratosis 4.6
porphyria cutanea tarda 4.6
magnesium deficiency 4.6
acute intermittent porphyria 4.6
HCA 4.5
quadriparesis 4.5
maple syrup urine disease 4.4
Anisakis 4.4
PER 4.2
hyperglycemia 4.2
anaplastic astrocytoma 4.1
thiamine deficiency 4.1
metabolic disorder 4.1
Appendix 4.1
Appendix 4.1
Appendix 4.1
glycogen storage disease 4.0
enzyme deficiency 3.9
Pulmonary arterial hypertension 3.9
severe mental retardation 3.9
Mitchell 3.8
brain edema 3.8
gallbladder cancer 3.8
macrocephaly 3.7
plant disease 3.7
AIN 3.7
hypernatremia 3.7
Rett syndrome 3.7
paraganglioma 3.6
failure to thrive 3.6
polycythemia 3.6
encephalopathy 3.5
mitochondrial disease 3.5
Andersen 3.5
premenstrual syndrome 3.5
glucose intolerance 3.4
gestational trophoblastic disease 3.4
PCC 3.4
type 2 diabetes 3.4
tapeworm 3.4
Friedreich's ataxia 3.3
chronic renal insufficiency 3.3
IVA 3.3
ALD 3.3
cor pulmonale 3.2
THC 3.2
bronchopneumonia 3.2
alkalosis 3.2
astrocytoma 3.2
status epilepticus 3.1
brain atrophy 3.1
telangiectasia 3.0
Merkel cell carcinoma 3.0
developmental delay 2.9
parasitic disease 2.9
diabetic ketoacidosis 2.9
retinopathy of prematurity 2.9
HPA 2.9
listeriosis 2.9
invasive cancer 2.8
PGA 2.7
coma 2.7
seminal vesicles 2.6
Nonalcoholic fatty liver 2.6
hyperthyroidism 2.6
diabetic neuropathy 2.6
iron deficiency 2.6
alcoholic fatty liver 2.5
yellow fever 2.5
pheochromocytoma 2.5
papillary thyroid cancer 2.4
mental retardation 2.4
mental retardation 2.4
agranulocytosis 2.4
sudden infant death syndrome 2.4
mole 2.2
genetic disorder 2.2
Huntington's disease 2.2
PCA 2.2
MRS 2.1
Ewing's sarcoma 2.1
SDS 2.1
glioma 2.0
diabetes 2.0
hyperlipidemia 2.0
Syndrome 2.0
mole 2.0
lung metastases 2.0
zoonosis 1.9
affective disorder 1.9
tuberous sclerosis 1.9
Mycobacterium 1.9
myopathy 1.8
gestational diabetes mellitus 1.8
uremia 1.8
dehydration 1.8
glioblastoma 1.8
hyperphagia 1.8
Brown 1.8
brucellosis 1.7
hemiparesis 1.7
type 1 diabetes 1.6
MCF 1.6
Schistosoma mansoni 1.5
memory impairment 1.5
malnutrition 1.5
nystagmus 1.5
respiratory failure 1.5
non-small cell lung cancer 1.5
fits 1.4
wasting 1.4
epilepsy 1.4
epididymis 1.3
obesity 1.3
thyroid cancer 1.3
Still 1.3
stomatitis 1.2
acute leukemia 1.2
neurological disease 1.2
cold 1.2
renal insufficiency 1.2
cerebral palsy 1.1
GSH 1.1
ICP 1.1
infestation 1.1
hepatocellular carcinoma 1.0
APC 1.0
deafness 1.0
peripheral neuropathy 1.0
cleft palate 1.0
renal cell carcinoma 0.9
gastroenteritis 0.9
epithelial ovarian cancer 0.9
metabolic syndrome 0.8
brain tumor 0.8
Evans 0.8
rare disease 0.7
depression 0.7
dermatitis 0.6
neuroblastoma 0.6
dyslipidemia 0.6
ovarian cancer 0.6
colon cancer 0.5
parkinsonism 0.5
preeclampsia 0.5
Mycoplasma 0.5
sepsis 0.5
hypercholesterolemia 0.5
ash 0.5
ischemia 0.5
Haemophilus 0.5
liver disease 0.4
breast cancer 0.4
hypothyroidism 0.4
virus infection 0.4
blindness 0.4
rash 0.3
worms 0.3
cerebral ischemia 0.3
sepsis 0.3
amyotrophic lateral sclerosis 0.1
tumorigenesis 0.1
tuberculosis 0.1
influenza 0.1
tumor growth 0.1
pancreatic cancer 0.0
cardiomyopathy 0.0
Parkinson's disease -0.0
adenoma -0.0
Klebsiella -0.1
melanoma -0.1
SEM -0.2
lung cancer -0.2
congestive heart failure -0.2
tumor -0.2
cystic fibrosis -0.3
sarcoma -0.3
Alzheimer's disease -0.4
addiction -0.4
herpes simplex -0.4
cytomegalovirus -0.4
abortion -0.5
cancer -0.7
uterus -0.7
hepatitis C -0.7
adenocarcinoma -0.7
heart failure -0.8
gastric cancer -0.8
stroke -0.8
West -0.8
tumor progression -1.0
cirrhosis -1.0
colorectal cancer -1.3
pneumonia -1.4
arthritis -1.7
lymphoma -1.8
carcinoma -1.9
atherosclerosis -1.9
leukemia -2.2
hypertension -3.0
Symptom
Tissue anoxia 12.0
Spots 5.5
ketonuria 5.2
hypotonia 5.2
lethargy 4.7
consciousness disturbance 4.7
starvation 4.1
incoordination 3.6
tachypnea 3.0
exhaustion 2.9
cerebellar ataxia 2.5
ataxia 2.4
hemiplegia 2.4
dystonia 2.3
myoclonus 2.3
vomiting 2.0
hunger 1.9
hepatomegaly 1.9
spasticity 1.7
seizures 1.7
anorexia 1.6
hypercapnia 1.4
hypothermia 1.3
constipation 1.0
Ill 0.9
agitation 0.8
acidity 0.5
tremor 0.2
respiratory distress 0.1
anesthesia -0.4
dyspnea -0.4
collapse -0.4
abdominal pain -0.6
fatigue -1.3
Drug
Formycin 10.6
p-Chlorophenyl 10.5
Posilac 10.0
Aspartic Acid 9.2
citric acid 7.1
Corn oil 7.1
Pentostam 7.0
Tween 40 6.8
CDX 6.4
Citric acid 6.4
Bezafibrate 6.2
Sodium valproate 6.0
Colombo 6.0
Glucagon 5.9
NADH 5.9
CDX 5.9
Arsenic trioxide 5.6
Glycerol 5.5
Alanine 5.5
Glutamic acid 5.4
Clofibrate 5.2
Fructose 5.0
DMI 4.9
Monensin 4.5
Galactose 4.3
Aloe 4.1
Vitamin B 4.1
Honey 4.0
lysine 4.0
lactose 3.9
FAD 3.5
Ethanol 3.4
G418 3.2
CDP 3.2
pyridoxal phosphate 3.1
Nitric Oxide 3.0
ALA 2.9
MRC 2.6
Gel 2.5
PCB 2.3
CSF 2.2
ROS 2.1
Asn 1.8
NH3 1.6
THF 1.4
ascorbate 0.9
MAP 0.4
vitamin E 0.3
caffeine -0.0
Leaf -0.0
Dermatol -3.6
Enzyme
pyruvate carboxylase 14.4
EC 4.1.1.40 13.4
methylcrotonyl-CoA carboxylase 12.9
acylpyruvate hydrolase 12.4
geranoyl-CoA carboxylase 12.4
CimA 12.0
biotin carboxylase 11.8
propionyl-CoA carboxylase 11.6
propionyl-CoA carboxylase 11.6
glycerophosphate phosphatase 11.6
transcarboxylase 11.4
diaminopimelate dehydrogenase 10.9
oxaloacetate decarboxylase 10.8
phosphoenolpyruvate carboxykinase 10.5
phosphoenolpyruvate carboxykinase 10.5
phosphoenolpyruvate carboxykinase 10.4
fructose 1,6-bisphosphatase 10.1
phosphoenolpyruvate carboxylase 10.0
pyruvate dehydrogenase 10.0
pyruvate dehydrogenase 10.0
EC 1.1.1.82 10.0
6-phosphogluconate dehydratase 10.0
EC 1.1.1.38 9.9
phosphoenolpyruvate synthase 9.9
biotinidase 9.8
alcohol acetyltransferase 9.7
pyruvate dehydrogenase 9.6
L-asparagine synthetase 9.6
EC 1.1.1.40 9.5
2-oxoglutarate decarboxylase 9.5
methylmalonate-semialdehyde dehydrogenase 9.4
citramalate synthase 9.3
citrate lyase 9.2
nicotinic acid phosphoribosyltransferase 9.2
diaminopimelate decarboxylase 9.1
glucose-6-phosphatase 9.1
isocitrate lyase 9.1
PPDK 9.0
citrate cleavage enzyme 9.0
acetoacetyl-CoA synthetase 9.0
oxoglutarate dehydrogenase 9.0
EC 1.1.1.39 9.0
fumarase 9.0
2-keto-3-deoxy-6-phosphogluconate aldolase 8.9
malate synthase 8.9
desulfinase 8.9
pyruvate:ferredoxin oxidoreductase 8.8
ribulose 5-phosphate 3-epimerase 8.8
acetyl-CoA carboxylase 8.8
GapB 8.8
EC 2.4.1.11 8.8
dihydrodipicolinate reductase 8.8
alpha-ketoglutarate dehydrogenase 8.7
desulfhydrase 8.7
acetyl-CoA hydrolase 8.6
sarcosine dehydrogenase 8.6
aspartokinase 8.5
branched-chain aminotransferase 8.5
pyruvate kinase 8.5
N-acetylglutamate kinase 8.5
pyruvate decarboxylase 8.4
malate dehydrogenase 8.4
citrate synthase 8.4
isocitrate dehydrogenase 8.3
PDH 8.3
acetate kinase 8.3
10-formyltetrahydrofolate dehydrogenase 8.3
isocitrate dehydrogenase 8.2
dihydrolipoamide succinyltransferase 8.2
glutamic dehydrogenase 8.1
lipoate acetyltransferase 8.1
beta-hydroxybutyrate dehydrogenase 8.1
CMP kinase 8.0
benzoylformate decarboxylase 8.0
pyruvate dehydrogenase phosphatase 7.9
acetyl-CoA synthetase 7.9
aconitase 7.8
HMG-CoA synthase 7.8
phosphofructokinase 7.8
phosphoglyceromutase 7.8
3-oxoacid CoA-transferase 7.8
hydroxyprostaglandin dehydrogenase 7.7
glycerol 3-phosphate dehydrogenase 7.7
acetolactate decarboxylase 7.7
glutamate dehydrogenase 7.7
glutamate dehydrogenase 7.7
glutamate dehydrogenase 7.7
carbamoylphosphate synthetase 7.7
aspartase 7.6
carnitine acetyltransferase 7.6
glucose permease 7.6
methylenetetrahydrofolate dehydrogenase 7.6
glutamine synthetase 7.5
argininosuccinate synthetase 7.5
arsenite oxidase 7.5
transhydrogenase 7.5
acyl-CoA synthetase 7.5
glucokinase 7.5
fumarate reductase 7.4
branched-chain alpha-keto acid dehydrogenase 7.3
homoserine kinase 7.3
rubisco 7.3
transaldolase 7.3
pyruvate oxidase 7.3
pyruvate oxidase 7.3
HCS 7.3
EC 3.6.1.1 7.3
CPS 7.2
glutaminase 7.2
dihydrodipicolinate synthase 7.1
methylenetetrahydrofolate dehydrogenase 7.1
fatty-acid synthase 7.1
acyl-CoA dehydrogenase 7.1
betaine-homocysteine methyltransferase 7.0
6-phosphogluconate dehydrogenase 7.0
6-phosphogluconate dehydrogenase 7.0
acetoacetyl-CoA thiolase 7.0
asparagine synthetase 7.0
xylulokinase 6.9
reductoisomerase 6.9
threonine deaminase 6.8
pyruvate formate-lyase 6.8
alcohol oxidase 6.8
ornithine transcarbamylase 6.8
hexokinase 6.7
glycerol-3-phosphate dehydrogenase 6.7
formate dehydrogenase 6.7
formate dehydrogenase 6.7
glycerol-3-phosphate dehydrogenase 6.7
lysine decarboxylase 6.7
succinyl-CoA synthetase 6.7
Mg-chelatase 6.6
uridyltransferase 6.6
acyl-CoA synthetase 6.6
formate dehydrogenase 6.6
diacylglycerol acyltransferase 6.6
glycerol dehydrogenase 6.5
lactic acid dehydrogenase 6.5
glycerol dehydrogenase 6.5
oxalate oxidase 6.5
acyl-CoA dehydrogenase 6.5
lactic acid dehydrogenase 6.5
glycerol kinase 6.4
pantothenate kinase 6.4
succinic dehydrogenase 6.4
bile salt hydrolase 6.4
glucose dehydrogenase 6.4
sucrose synthase 6.3
condensing enzyme 6.3
MDH 6.3
xylitol dehydrogenase 6.3
alanine dehydrogenase 6.3
xylitol dehydrogenase 6.2
glycine decarboxylase 6.2
MDH 6.2
fumarylacetoacetate hydrolase 6.2
leucyl-tRNA synthetase 6.1
succinic semialdehyde dehydrogenase 6.1
phosphoglycerate kinase 6.1
acetolactate synthase 6.0
PDK1 6.0
phosphoglycerate dehydrogenase 6.0
transketolase 6.0
succinate dehydrogenase 6.0
3-hydroxyacyl-CoA dehydrogenase 6.0
glucose-6-phosphate dehydrogenase 6.0
3-hydroxyacyl-CoA dehydrogenase 5.9
oxidosqualene cyclase 5.9
glyceraldehyde-3-phosphate dehydrogenase 5.9
glutamate synthase 5.8
lactic acid dehydrogenase 5.8
glutamate synthase 5.8
diaphorase 5.7
methylmalonyl-CoA mutase 5.7
glutamate synthase 5.7
ACC synthase 5.7
GABA transaminase 5.7
methionine synthase 5.7
endoproteinase Glu-C 5.6
halogenase 5.6
PTA 5.6
sulfite oxidase 5.6
methionine synthase 5.5
uroporphyrinogen decarboxylase 5.5
sulfite oxidase 5.5
adenylate kinase 5.4
lactate dehydrogenase 5.4
prolidase 5.4
O-GlcNAc transferase 5.4
SCS 5.4
phosphoribulokinase 5.3
ECH 5.3
carbonic anhydrase 5.3
sorbitol dehydrogenase 5.3
glyceraldehyde-3-phosphate dehydrogenase 5.3
phosphoglucose isomerase 5.2
aspartate aminotransferase 5.2
HSD 5.2
ATP synthase 5.2
serine hydroxymethyltransferase 5.2
glyceraldehyde-3-phosphate dehydrogenase 5.2
glyceraldehyde-3-phosphate dehydrogenase 5.1
cysteine synthase 5.1
p-nitrophenylphosphatase 5.1
glyceraldehyde-3-phosphate dehydrogenase 5.0
CPT 5.0
glutathione synthetase 5.0
PGM 4.9
ornithine aminotransferase 4.9
alanine aminopeptidase 4.8
arginase 4.8
CEP 4.8
AGT 4.8
peptidyl-prolyl cis-trans isomerase 4.7
CFI 4.7
BAT 4.7
aldolase 4.6
GRK2 4.6
KAT 4.6
peroxiredoxin 4.6
ferrochelatase 4.5
enolase 4.5
firefly luciferase 4.5
phosphorylase 4.5
ascorbate peroxidase 4.5
cystathionine beta-synthase 4.4
diaphorase 4.4
ALA synthase 4.4
alanine aminotransferase 4.4
alcohol dehydrogenase 4.3
CPT 4.3
NADH dehydrogenase 4.3
hormone-sensitive lipase 4.3
aldehyde dehydrogenase 4.3
aldehyde dehydrogenase 4.3
aldehyde dehydrogenase 4.2
3-hydroxy-3-methylglutaryl-CoA reductase 4.2
CPT 4.2
urease 4.1
cytochrome oxidase 4.1
heparinase 4.0
TPP 4.0
aldehyde dehydrogenase 4.0
aldehyde dehydrogenase 4.0
tyrosine aminotransferase 4.0
AMP-activated protein kinase 4.0
LPL 3.9
TPP 3.9
3-hydroxy-3-methylglutaryl coenzyme A reductase 3.8
Mg2+-ATPase 3.8
apyrase 3.8
AMPK 3.7
ACE 3.7
CPR 3.6
lipoprotein lipase 3.6
complex I 3.6
CD13 3.5
nitrate reductase 3.5
nitrate reductase 3.5
nitrate reductase 3.5
nitrate reductase 3.5
nitrate reductase 3.5
MPP 3.5
thermolysin 3.5
nitrate reductase 3.4
HIV-1 protease 3.3
methylenetetrahydrofolate reductase 3.3
lactase 3.3
methylenetetrahydrofolate reductase 3.3
glutamate decarboxylase 3.3
N-acetyltransferase 3.2
urease 3.1
invertase 3.1
AMPK 3.1
luciferase 3.0
beta-glucuronidase 3.0
MDP 3.0
ornithine decarboxylase 2.7
hydrogenase 2.6
hydrogenase 2.6
phospholipase D 2.5
adenylate cyclase 2.5
NADPH-diaphorase 2.4
superoxide dismutase 2.3
alpha-glucosidase 2.3
MDR 2.3
CAD 2.2
P-glycoprotein 2.2
transcriptase 2.1
glutathione reductase 2.1
beta-galactosidase 2.1
IKK 2.1
kinesin 2.1
catalase 2.1
ceruloplasmin 2.0
alkaline phosphatase 2.0
ATPase 1.9
chymotrypsin 1.9
dihydrofolate reductase 1.9
AST 1.8
NQO1 1.8
phosphodiesterase 1.7
GSK 1.6
RNA polymerase 1.6
tyrosine hydroxylase 1.5
protein kinase 1.5
glutathione S-transferase 1.5
RNase 1.4
protein kinase C 1.4
trypsin 1.3
lipoxygenase 1.3
RNase 1.2
gamma-glutamyl transpeptidase 1.2
lipase 1.2
creatine kinase 1.2
ACS 1.1
NADPH oxidase 1.0
reverse transcriptase 1.0
phosphatidylinositol 3-kinase 0.9
NADPH oxidase 0.9
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Compound
6-aminotryptophan 14.4
Chlorothricin 13.4
2-hydroxyethyl carbamate 12.0
Decanoylcarnitine 11.8
PYC 11.5
Fluoropyruvate 11.2
O-acetylcarnitine 11.2
N-formimino-l-glutamate 11.0
Butylmalonate 11.0
3-methylcrotonyl-CoA 10.9
2,4-pyrimidinediamine 10.7
Oxamate 10.3
3-hydroxyisovaleric acid 10.1
Phenylpyruvate 10.0
oxalacetate 9.9
dimethyl malate 9.8
beta-methylcrotonic acid 9.8
propionyl-coenzyme A 9.5
Ethoxzolamide 9.5
TPTA 9.3
acetyl-CoA 9.2
benzoylformic acid 9.0
Metribuzin 9.0
dimethyl succinate 8.9
Nialamide 8.8
2-Oxoglutarate 8.8
2-oxobutyrate 8.7
Biotin 8.7
Pyruvate 8.6
2-oxobutyrate 8.4
Amytal 8.3
isocitrate 8.2
Acetyl phosphate 8.2
malic acid 8.1
malic acid 8.1
malic acid 8.1
malic acid 8.1
Pyruvate kinase 7.9
1-Methyl-4-phenylpyridinium 7.9
2-oxoglutarate 7.9
Ponceau S 7.8
Malate 7.8
PEP 7.8
phenylacetic acid 7.7
phenylacetic acid 7.7
phenylacetic acid 7.7
PDH 7.7
erythrose-4-phosphate 7.7
phenylacetic acid 7.7
Glyoxylate 7.6
2-oxoadipate 7.6
glutaryl-CoA 7.5
phenylarsonic acid 7.5
CoA 7.5
pentose 7.4
pentose 7.4
Flux 7.4
pentose 7.4
6-phosphogluconate 7.4
TCA 7.4
sedoheptulose 7-phosphate 7.3
pentose 7.3
acetoacetyl-CoA 7.3
DTB 7.3
DTB 7.3
Selenate 7.3
Fumarate 7.2
DTB 7.2
Biocytin 7.2
phenyl acetate 7.1
MAL 7.1
succinic acid 7.1
succinic acid 7.1
succinic acid 7.1
succinic acid 7.1
2-phosphoglycerate 7.1
4-pentenoic acid 7.1
IDP 7.1
glutamine 7.1
sulfamic acid 7.0
sulfamic acid 7.0
CPIB 7.0
acetylglutamate 7.0
succinic acid 7.0
Propionate 7.0
Dihydroxyacetone 6.9
Glutamine 6.9
carbamyl phosphate 6.8
Glycerol-3-phosphate 6.7
Arsenite 6.7
10-formyltetrahydrofolate 6.7
malonyl-CoA 6.6
Ribulose 6.6
PYR 6.6
meso-diaminopimelate 6.6
Ethacrynic acid 6.6
HBA 6.6
NADP 6.5
Triamcinolone 6.5
PBG 6.4
DIM 6.4
itaconic acid 6.4
PTS 6.4
sulfamic acid 6.4
Glutamate 6.4
hydroxycinnamic acid 6.3
Ethacrynic acid 6.3
glucose-6-phosphate 6.3
hexuronic acid 6.3
Oleic acid 6.2
Clofibrate 6.1
Glycine, 6.1
Bacitracin 6.1
sulfamide 6.1
sulfamide 6.1
MAK 6.1
Phlorizin 6.1
glutamate 6.0
alpha-ketoisocaproate 5.9
Glucagon 5.9
Cefazolin 5.9
NADH 5.9
Lactate 5.9
Quinolinic acid 5.9
CIT 5.9
hexanoic acid 5.9
Glucose 6-phosphate 5.8
perchloric acid 5.8
hexanoic acid 5.8
Hydrazine 5.8
Glycine, 5.8
NAD 5.8
alloxan 5.7
NAD 5.7
HCO 5.7
ribose-5-phosphate 5.7
Alanine 5.6
SP-1 5.6
fructose-6-P 5.6
alanine 5.5
Diazoxide 5.5
glucose 5.5
Xylose 5.5
glycerol 5.4
Coomassie Blue 5.4
phthalaldehyde 5.4
hippurate 5.4
L-threonine 5.4
ADP 5.4
ADP 5.3
dicarboxylic acid 5.3
Conjugated linoleic acid 5.3
Chlorogenic acid 5.3
palmitoyl-CoA 5.3
Glu-Glu 5.2
PGFM 5.2
ADP 5.2
TPP 5.2
decanoic acid 5.2
Zearalenone 5.1
hexose 5.1
hexose 5.1
hexose 5.1
Glibenclamide 5.1
propionaldehyde 5.1
OHB 5.1
ornithine 5.1
ornithine 5.1
ornithine 5.1
ornithine 5.1
ornithine 5.1
NADPH 5.1
NADPH 5.1
G3P 5.1
decanoic acid 5.0
Fructose 5.0
DCMU 5.0
ATP 4.9
Dichloroacetate 4.9
Lip 4.9
cinnamyl 4.9
cinnamyl 4.8
DMI 4.8
DMI 4.8
CO2 4.8
2,3-butanediol 4.7
2,3-butanediol 4.7
2,3-butanediol 4.7
N-acetylaspartate 4.7
Rotenone 4.7
aspartic acid 4.7
PMS 4.7
HCA 4.6
norleucine 4.6
AAT 4.6
hexose 4.6
adenylate 4.6
propylene glycol 4.5
Monensin 4.5
MVA 4.5
Pectin 4.5
dihydrofolate 4.5
hydroxyglutarate 4.4
C-3 4.4
Thioredoxin 4.4
NEM 4.4
FDP 4.4
GABA 4.4
asparagine 4.4
GABA 4.4
propylene glycol 4.4
Hypo 4.4
Dexamethasone 4.4
GAP 4.3
CPT 4.3
octanoic acid 4.3
octanoic acid 4.3
Creatine 4.3
alcohol dehydrogenase 4.3
Galactose 4.3
octanoic acid 4.3
phenylboronic acid 4.3
norleucine 4.3
octanoic acid 4.3
Carbon 4.2
DAG 4.2
oxalate 4.2
octanoic acid 4.2
CPT 4.2
betaine 4.1
Cycloheximide 4.1
AMP 4.1
1H-pyrazole 4.1
acetate 4.1
Thiamine 4.1
carbonate 4.1
Homocysteine 4.0
gamma-aminobutyric acid 4.0
phosphate 4.0
Homocysteine 4.0
urea 4.0
UDP-glucose 4.0
cinnamyl 3.9
glutamic acid 3.9
TPP 3.9
ammonia 3.9
Benzene 3.9
Mg2+ 3.9
ANA 3.9
ANA 3.9
HMG-CoA 3.9
Histidine 3.9
LIN 3.9
A 42 3.8
aspartic acid 3.8
aspartic acid 3.8
homoserine 3.8
homoserine 3.8
heptane 3.8
homoserine 3.7
MgCl2 3.7
CDP 3.7
PLP 3.7
phosphocreatine 3.7
oxalic acid 3.6
MPP 3.6
TPP 3.6
Insulin 3.6
MPP 3.6
lysine 3.6
aspartic acid 3.5
valine 3.5
Choline 3.5
hydrazine 3.5
Cortisol 3.5
FAD 3.5
1-propanol 3.5
GSSG 3.5
L-carnitine 3.5
PAM 3.4
PAM 3.4
CMP 3.4
Asp 3.4
MCP 3.4
Methionine 3.4
Cereb 3.4
proline 3.4
PPi 3.4
manganese 3.4
CMP 3.4
Phorbol 3.4
nicotinamide 3.4
UDP 3.4
PHB 3.3
acetic acid 3.3
PPI 3.3
xylose 3.3
propionic acid 3.3
propionic acid 3.3
FFA 3.3
APS 3.3
CdCl2 3.3
methionine 3.3
threonine 3.3
kaempferol 3.2
Hoechst 33342 3.2
Taurine 3.2
ASC 3.2
Glycogen 3.2
GAL 3.1
Sucrose 3.1
Leucine 3.1
L-leucine 3.1
Betula 3.1
NTA 3.1
phenazine 3.1
serine 3.1
ammonium 3.0
Amphotericin B 3.0
phosphoserine 3.0
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