Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.4.1.1 (pyruvate carboxylase)
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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
pyruvate carboxylase 0.933
Pyruvate carboxylase 0.055
phosphoenolpyruvate carboxykinase 0.013
propionyl-CoA carboxylase 0.005
pyruvate dehydrogenase 0.005
biotin carboxylase 0.004
ASCI 0.003
phosphoenolpyruvate carboxylase 0.002
pyruvate carboxylase, mitochondrial 0.002
holocarboxylase synthetase 0.002
glucose-6-phosphatase 0.001
pyruvate kinase 0.001
malate dehydrogenase 0.001
CGI-49 0.001
acetyl-CoA carboxylase 0.001
carboxylating 0.001
citrate synthase 0.001
SDHC protein 0.001
TCA 0.001
PCK2 0.001
fumarase 0.001
biotinidase 0.001
succinyl-CoA:3-ketoacid-CoA transferase 0.001
CA V 0.001
PEPCK-M 0.001
isocitrate dehydrogenase 0.000
fructose 1,6-bisphosphatase 0.000
PCK1 0.000
pyruvate dehydrogenase complex 0.000
Malic enzyme 0.000
PEPCK-C 0.000
TOP2 beta 0.000
ATP5J2 0.000
PEPCK 0.000
Holocarboxylase synthetase 0.000
carnitine palmitoyltransferase 1A 0.000
acyl-CoA dehydrogenase 9 0.000
glutamine synthetase 0.000
glutamate dehydrogenase 0.000
decarboxylating 0.000
L-alanine:glyoxylate aminotransferase 0.000
phosphofructokinase 0.000
phosphoenolpyruvate carboxykinase 1 0.000
2-oxoglutarate dehydrogenase 0.000
ATPase homolog 0.000
BPC1 0.000
fructose-1,6-bisphosphatase 1 0.000
fructose-1,6-bisphosphatase 0.000
aconitate hydratase 0.000
MCCC2 0.000
ATP 0.000
ODPA 0.000
ACSS3 0.000
3-hydroxybutyrate dehydrogenase 0.000
pccA 0.000
Max-like protein X 0.000
Pyruvate dehydrogenase 0.000
D-fructose-1,6-bisphosphate 1-phosphohydrolase 0.000
mitochondrial citrate transport protein 0.000
ATP citrate lyase 0.000
phosphoenolpyruvate carboxykinase 2 0.000
CO2 0.000
ME3 0.000
glucokinase 0.000
INS-1 0.000
PDH 0.000
G6Pase 0.000
NADP 0.000
alpha-ketoglutarate dehydrogenase 0.000
PDC2 0.000
NADH 0.000
TALH 0.000
LYS5 0.000
sodium-dependent multivitamin transporter 0.000
6-phosphofructokinase 0.000
MAEA 0.000
CA5 0.000
Malate dehydrogenase 0.000
Phosphoserine phosphatase 0.000
glycerol-3-phosphate dehydrogenase 1 0.000
ME4 0.000
carbamoylphosphate synthetase I 0.000
insulin 0.000
PEP 0.000
glucagon 0.000
oxoglutarate 0.000
ADP 0.000
steroid dehydrogenase-like protein 0.000
nicotinic acid phosphoribosyltransferase 0.000
hexokinase 0.000
RagD 0.000
aconitase 0.000
CS-3 0.000
ubiquinol-cytochrome c reductase complex 0.000
SLC25A1 0.000
OPA3 0.000
NEFA 0.000
Nicotinamide nucleotide transhydrogenase 0.000
S3-12 0.000
MCCC1 0.000
Fructose 1,6-bisphosphatase 0.000
5-methyltetrahydrofolate-homocysteine methyltransferase 0.000
NAD 0.000
lactate dehydrogenase 0.000
phosphoglyceromutase 0.000
Isocitrate dehydrogenase 0.000
carbamoylphosphate synthetase 0.000
acetyl-CoA synthetase 0.000
Phosphoglycerate dehydrogenase 0.000
IST1 0.000
acetyl-CoA carboxylase 1 0.000
acetoacetyl-CoA synthetase 0.000
E1 alpha 0.000
MUL 0.000
PSPH 0.000
arylsulfatase E 0.000
MDH2 0.000
hepatocyte nuclear factor 1 alpha 0.000
argininosuccinate synthetase 0.000
SP-22 0.000
USF1 0.000
isocitric dehydrogenase 0.000
PGC1A 0.000
glutaminase 0.000
ACC1 0.000
SARP 0.000
lactate dehydrogenase-A 0.000
aspartate aminotransferase 0.000
HMGCS1 0.000
citrate transport protein 0.000
PEX10 0.000
Pyruvate kinase 0.000
CS-2 0.000
ACADVL 0.000
methylmalonate-semialdehyde dehydrogenase 0.000
glyceraldehyde 3-phosphate dehydrogenase 0.000
USF2 0.000
SSB1 0.000
NAD+ 0.000
NADP-ME 0.000
MDH1 0.000
PSAT1 0.000
ASNS 0.000
Glucose-6-phosphatase 0.000
NM23-H2 0.000
AGC1 0.000
ACL 0.000
glutamic dehydrogenase 0.000
CA II 0.000
6-phosphogluconate dehydrogenase 0.000
NADP-malic enzyme 0.000
LPMC 0.000
PDK2 0.000
NADPH 0.000
sarcosine dehydrogenase 0.000
NOX3 0.000
CA VII 0.000
Spot14 0.000
CA IV 0.000
PHGDH 0.000
more...
Disease
PC deficiency 0.002
Biotin deficiency 0.001
Multiple carboxylase deficiency 0.001
Avian reticuloendotheliosis 0.000
hyperlysinemia 0.000
lactic acidosis 0.000
Organic acidemias 0.000
Ketonemia 0.000
Leigh syndrome 0.000
MGA3 0.000
MILS 0.000
encephalomyelopathy 0.000
Goodall 0.000
Hers 0.000
hypoglycemia 0.000
Carcinoma ex pleomorphic adenoma 0.000
propionic acidemia 0.000
Reye's syndrome 0.000
citrullinemia 0.000
disorders of amino acid metabolism 0.000
Alpers 0.000
PDH deficiency 0.000
Biotinidase deficiency 0.000
Ondine's curse 0.000
marijuana abuse 0.000
methylmalonic acidemia 0.000
Ondine's curse 0.000
fatty liver 0.000
glutaric aciduria 0.000
ketosis 0.000
hyperglycemia 0.000
Reye 0.000
insulinoma 0.000
kidney hypertrophy 0.000
mitochondrial encephalomyopathy 0.000
hepatic porphyria 0.000
Barth syndrome 0.000
type 2 diabetes 0.000
GSD I 0.000
RDP 0.000
renal tubular acidosis 0.000
BCH 0.000
lipidosis 0.000
Wernicke's encephalopathy 0.000
hepatic encephalopathy 0.000
PDC 0.000
Benson 0.000
Forbes 0.000
porphyria 0.000
Sutton 0.000
diabetes 0.000
FDH 0.000
marasmus 0.000
clonorchiasis 0.000
MELAS 0.000
mitochondrial myopathy 0.000
profound mental retardation 0.000
laryngospasm 0.000
MELAS 0.000
encephalopathy 0.000
hyperphenylalaninemia 0.000
hypophosphatasia 0.000
AIP 0.000
MCD 0.000
cystinuria 0.000
GSD 0.000
Korsakoff's syndrome 0.000
AIP 0.000
Kearns-Sayre syndrome 0.000
reticuloendotheliosis 0.000
GSD 0.000
Acute liver failure 0.000
dysphasia 0.000
porphyria cutanea tarda 0.000
PMS 0.000
metabolic disorder 0.000
DWI 0.000
PCT 0.000
kwashiorkor 0.000
parakeratosis 0.000
magnesium deficiency 0.000
acute intermittent porphyria 0.000
HCA 0.000
quadriparesis 0.000
maple syrup urine disease 0.000
glucose intolerance 0.000
Anisakis 0.000
brain edema 0.000
PER 0.000
anaplastic astrocytoma 0.000
thiamine deficiency 0.000
Appendix 0.000
Appendix 0.000
Appendix 0.000
glycogen storage disease 0.000
enzyme deficiency 0.000
Pulmonary arterial hypertension 0.000
severe mental retardation 0.000
Rett syndrome 0.000
Mitchell 0.000
PCC 0.000
paraganglioma 0.000
failure to thrive 0.000
gallbladder cancer 0.000
macrocephaly 0.000
plant disease 0.000
AIN 0.000
hypernatremia 0.000
SDS 0.000
coma 0.000
astrocytoma 0.000
polycythemia 0.000
status epilepticus 0.000
mitochondrial disease 0.000
Andersen 0.000
premenstrual syndrome 0.000
obesity 0.000
gestational trophoblastic disease 0.000
tapeworm 0.000
developmental delay 0.000
Mycobacterium 0.000
Friedreich's ataxia 0.000
chronic renal insufficiency 0.000
IVA 0.000
brain atrophy 0.000
ALD 0.000
cor pulmonale 0.000
THC 0.000
bronchopneumonia 0.000
alkalosis 0.000
pheochromocytoma 0.000
glioma 0.000
mental retardation 0.000
mental retardation 0.000
hyperthyroidism 0.000
telangiectasia 0.000
Merkel cell carcinoma 0.000
parasitic disease 0.000
diabetic ketoacidosis 0.000
retinopathy of prematurity 0.000
HPA 0.000
mole 0.000
listeriosis 0.000
cold 0.000
invasive cancer 0.000
PGA 0.000
iron deficiency 0.000
epilepsy 0.000
tumor 0.000
seminal vesicles 0.000
mole 0.000
Huntington's disease 0.000
Nonalcoholic fatty liver 0.000
depression 0.000
diabetic neuropathy 0.000
alcoholic fatty liver 0.000
yellow fever 0.000
cancer 0.000
dehydration 0.000
papillary thyroid cancer 0.000
more...
Symptom
Tissue anoxia 0.000
hypotonia 0.000
starvation 0.000
lethargy 0.000
Spots 0.000
ketonuria 0.000
consciousness disturbance 0.000
exhaustion 0.000
incoordination 0.000
seizures 0.000
ataxia 0.000
tachypnea 0.000
vomiting 0.000
cerebellar ataxia 0.000
dystonia 0.000
hemiplegia 0.000
myoclonus 0.000
hunger 0.000
hepatomegaly 0.000
anorexia 0.000
spasticity 0.000
hypothermia 0.000
hypercapnia 0.000
constipation 0.000
Ill 0.000
agitation 0.000
acidity 0.000
anesthesia 0.000
tremor 0.000
respiratory distress 0.000
dyspnea 0.000
collapse 0.000
abdominal pain 0.000
fatigue 0.000
Drug
citric acid 0.000
Formycin 0.000
p-Chlorophenyl 0.000
Posilac 0.000
NADH 0.000
Aspartic Acid 0.000
Glucagon 0.000
lysine 0.000
Corn oil 0.000
Pentostam 0.000
Tween 40 0.000
Alanine 0.000
Citric acid 0.000
Glycerol 0.000
CDX 0.000
Bezafibrate 0.000
Arsenic trioxide 0.000
Sodium valproate 0.000
Colombo 0.000
CDX 0.000
lactose 0.000
Fructose 0.000
Glutamic acid 0.000
DMI 0.000
Clofibrate 0.000
Monensin 0.000
Galactose 0.000
Ethanol 0.000
Aloe 0.000
Vitamin B 0.000
Honey 0.000
FAD 0.000
CSF 0.000
G418 0.000
CDP 0.000
Gel 0.000
pyridoxal phosphate 0.000
Nitric Oxide 0.000
ALA 0.000
ROS 0.000
MRC 0.000
PCB 0.000
Asn 0.000
NH3 0.000
THF 0.000
ascorbate 0.000
MAP 0.000
vitamin E 0.000
caffeine 0.000
Leaf 0.000
Dermatol 0.000
Enzyme
pyruvate carboxylase 0.999
phosphoenolpyruvate carboxykinase 0.014
phosphoenolpyruvate carboxykinase 0.014
phosphoenolpyruvate carboxykinase 0.012
methylcrotonyl-CoA carboxylase 0.008
pyruvate dehydrogenase 0.006
pyruvate dehydrogenase 0.006
propionyl-CoA carboxylase 0.005
propionyl-CoA carboxylase 0.005
pyruvate dehydrogenase 0.005
biotin carboxylase 0.005
phosphoenolpyruvate carboxylase 0.003
fructose 1,6-bisphosphatase 0.002
glucose-6-phosphatase 0.001
transcarboxylase 0.001
pyruvate kinase 0.001
acetyl-CoA carboxylase 0.001
oxaloacetate decarboxylase 0.001
malate dehydrogenase 0.001
citrate synthase 0.001
geranoyl-CoA carboxylase 0.001
EC 4.1.1.40 0.001
biotinidase 0.001
isocitrate dehydrogenase 0.001
isocitrate dehydrogenase 0.000
fumarase 0.000
isocitrate lyase 0.000
acylpyruvate hydrolase 0.000
CimA 0.000
alpha-ketoglutarate dehydrogenase 0.000
diaminopimelate dehydrogenase 0.000
glycerophosphate phosphatase 0.000
glutamate dehydrogenase 0.000
glutamate dehydrogenase 0.000
phosphofructokinase 0.000
glutamate dehydrogenase 0.000
glutamine synthetase 0.000
malate synthase 0.000
EC 1.1.1.40 0.000
citrate lyase 0.000
pyruvate decarboxylase 0.000
6-phosphogluconate dehydratase 0.000
phosphoenolpyruvate synthase 0.000
aconitase 0.000
glucokinase 0.000
EC 1.1.1.82 0.000
PDH 0.000
alcohol acetyltransferase 0.000
EC 1.1.1.38 0.000
aspartokinase 0.000
PPDK 0.000
pyruvate:ferredoxin oxidoreductase 0.000
oxoglutarate dehydrogenase 0.000
hexokinase 0.000
L-asparagine synthetase 0.000
acetate kinase 0.000
2-oxoglutarate decarboxylase 0.000
lactate dehydrogenase 0.000
methylmalonate-semialdehyde dehydrogenase 0.000
nicotinic acid phosphoribosyltransferase 0.000
diaminopimelate decarboxylase 0.000
citramalate synthase 0.000
citrate cleavage enzyme 0.000
branched-chain aminotransferase 0.000
2-keto-3-deoxy-6-phosphogluconate aldolase 0.000
glutaminase 0.000
acetoacetyl-CoA synthetase 0.000
beta-hydroxybutyrate dehydrogenase 0.000
EC 1.1.1.39 0.000
rubisco 0.000
desulfinase 0.000
ribulose 5-phosphate 3-epimerase 0.000
succinate dehydrogenase 0.000
dihydrodipicolinate reductase 0.000
GapB 0.000
EC 2.4.1.11 0.000
acetyl-CoA synthetase 0.000
CPS 0.000
acyl-CoA synthetase 0.000
desulfhydrase 0.000
HMG-CoA synthase 0.000
glucose-6-phosphate dehydrogenase 0.000
argininosuccinate synthetase 0.000
glutamic dehydrogenase 0.000
aspartate aminotransferase 0.000
transhydrogenase 0.000
6-phosphogluconate dehydrogenase 0.000
sarcosine dehydrogenase 0.000
acetyl-CoA hydrolase 0.000
6-phosphogluconate dehydrogenase 0.000
N-acetylglutamate kinase 0.000
carnitine acetyltransferase 0.000
lipoate acetyltransferase 0.000
ornithine transcarbamylase 0.000
fumarate reductase 0.000
glycerol-3-phosphate dehydrogenase 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
glycerol-3-phosphate dehydrogenase 0.000
dihydrolipoamide succinyltransferase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
carbamoylphosphate synthetase 0.000
CMP kinase 0.000
benzoylformate decarboxylase 0.000
phosphoglyceromutase 0.000
acyl-CoA dehydrogenase 0.000
glycerol 3-phosphate dehydrogenase 0.000
pyruvate dehydrogenase phosphatase 0.000
aspartase 0.000
branched-chain alpha-keto acid dehydrogenase 0.000
3-oxoacid CoA-transferase 0.000
transaldolase 0.000
hydroxyprostaglandin dehydrogenase 0.000
acetolactate decarboxylase 0.000
HCS 0.000
acyl-CoA synthetase 0.000
succinic dehydrogenase 0.000
glucose permease 0.000
formate dehydrogenase 0.000
formate dehydrogenase 0.000
methylenetetrahydrofolate dehydrogenase 0.000
acyl-CoA dehydrogenase 0.000
arsenite oxidase 0.000
formate dehydrogenase 0.000
pyruvate oxidase 0.000
pyruvate oxidase 0.000
alcohol oxidase 0.000
asparagine synthetase 0.000
homoserine kinase 0.000
carbonic anhydrase 0.000
phosphoglycerate kinase 0.000
EC 3.6.1.1 0.000
PDK1 0.000
diacylglycerol acyltransferase 0.000
acetoacetyl-CoA thiolase 0.000
alanine aminotransferase 0.000
dihydrodipicolinate synthase 0.000
methylenetetrahydrofolate dehydrogenase 0.000
fatty-acid synthase 0.000
reductoisomerase 0.000
betaine-homocysteine methyltransferase 0.000
glucose dehydrogenase 0.000
threonine deaminase 0.000
ATP synthase 0.000
diaphorase 0.000
xylulokinase 0.000
lysine decarboxylase 0.000
succinyl-CoA synthetase 0.000
glycerol kinase 0.000
pyruvate formate-lyase 0.000
sucrose synthase 0.000
MDH 0.000
lactic acid dehydrogenase 0.000
transketolase 0.000
Mg-chelatase 0.000
lactic acid dehydrogenase 0.000
uridyltransferase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
MDH 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glycerol dehydrogenase 0.000
more...
Compound
acetyl-CoA 0.003
oxalacetate 0.001
Chlorothricin 0.001
PYC 0.001
6-aminotryptophan 0.001
glucose 0.001
3-methylcrotonyl-CoA 0.001
CoA 0.001
glutamine 0.001
2-oxoglutarate 0.001
glutamate 0.000
Pyruvate 0.000
Biotin 0.000
3-hydroxyisovaleric acid 0.000
2-hydroxyethyl carbamate 0.000
TCA 0.000
Decanoylcarnitine 0.000
malic acid 0.000
pentose 0.000
pentose 0.000
pentose 0.000
pentose 0.000
isocitrate 0.000
Fluoropyruvate 0.000
O-acetylcarnitine 0.000
malic acid 0.000
malic acid 0.000
malic acid 0.000
Butylmalonate 0.000
N-formimino-l-glutamate 0.000
alanine 0.000
Oxamate 0.000
ATP 0.000
PEP 0.000
2,4-pyrimidinediamine 0.000
NADP 0.000
Phenylpyruvate 0.000
NADH 0.000
propionyl-coenzyme A 0.000
NAD 0.000
glycerol 0.000
CO2 0.000
dimethyl malate 0.000
beta-methylcrotonic acid 0.000
ADP 0.000
ADP 0.000
2-oxobutyrate 0.000
succinic acid 0.000
phenylacetic acid 0.000
ADP 0.000
phenylacetic acid 0.000
phenylacetic acid 0.000
phenylacetic acid 0.000
Flux 0.000
Ethoxzolamide 0.000
NAD 0.000
PDH 0.000
2-oxobutyrate 0.000
TPTA 0.000
succinic acid 0.000
succinic acid 0.000
succinic acid 0.000
succinic acid 0.000
2-Oxoglutarate 0.000
Glutamate 0.000
phosphate 0.000
benzoylformic acid 0.000
Metribuzin 0.000
dimethyl succinate 0.000
Malate 0.000
Nialamide 0.000
Pyruvate kinase 0.000
acetate 0.000
Amytal 0.000
Glutamine 0.000
NADPH 0.000
NADPH 0.000
Lactate 0.000
glucose-6-phosphate 0.000
MAL 0.000
Acetyl phosphate 0.000
malonyl-CoA 0.000
6-phosphogluconate 0.000
glutaryl-CoA 0.000
1-Methyl-4-phenylpyridinium 0.000
Ponceau S 0.000
Glyoxylate 0.000
acetoacetyl-CoA 0.000
erythrose-4-phosphate 0.000
Glucagon 0.000
Fumarate 0.000
GABA 0.000
urea 0.000
Propionate 0.000
HCO 0.000
GABA 0.000
2-oxoadipate 0.000
hydroxycinnamic acid 0.000
phenylarsonic acid 0.000
AMP 0.000
sedoheptulose 7-phosphate 0.000
phenyl acetate 0.000
alloxan 0.000
2-phosphoglycerate 0.000
DTB 0.000
DTB 0.000
IDP 0.000
CIT 0.000
Selenate 0.000
carbamyl phosphate 0.000
perchloric acid 0.000
DTB 0.000
acetylglutamate 0.000
lysine 0.000
Biocytin 0.000
Arsenite 0.000
4-pentenoic acid 0.000
Oleic acid 0.000
PYR 0.000
sulfamic acid 0.000
sulfamic acid 0.000
ammonia 0.000
CPIB 0.000
HBA 0.000
Dihydroxyacetone 0.000
DIM 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
Ribulose 0.000
PTS 0.000
carbonate 0.000
dicarboxylic acid 0.000
hexose 0.000
hexose 0.000
hexose 0.000
Glycerol-3-phosphate 0.000
aspartic acid 0.000
10-formyltetrahydrofolate 0.000
Alanine 0.000
itaconic acid 0.000
meso-diaminopimelate 0.000
Ethacrynic acid 0.000
Triamcinolone 0.000
PBG 0.000
sulfamic acid 0.000
Mg2+ 0.000
Clofibrate 0.000
Ethacrynic acid 0.000
hexuronic acid 0.000
MAK 0.000
asparagine 0.000
hexose 0.000
methionine 0.000
Glycine, 0.000
alpha-ketoisocaproate 0.000
Bacitracin 0.000
sulfamide 0.000
more...