Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.5.5 (CPS)
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Human Gene/Protein
WDR73 protein 14.6
glutamine-hydrolyzing 14.4
CPS 14.2
KPB1 12.6
Zinc finger protein A20 12.3
CAD protein 12.0
WDR73 11.8
carbamoylphosphate synthetase 11.5
EXOG 11.0
Argininosuccinate synthase 10.9
CRKL protein 10.9
crn 10.8
phospholipase D3 10.8
CPS1 10.7
BTN2 10.7
Rheb2 10.7
N-acetylglutamate synthase 10.6
N-acetylglutamate synthetase 10.6
CPA1 10.5
CPA2 10.4
SERAC1 10.4
glutamine amidotransferase 10.3
CED-12 10.2
Pyruvate carboxylase 10.0
CED-6 10.0
phosphoribosyl pyrophosphate amidotransferase 10.0
carbamoylphosphate synthetase I 10.0
OTC 10.0
argininosuccinate synthase 10.0
argininosuccinate lyase 10.0
adenylosuccinate synthase 10.0
CA V 10.0
argininosuccinate synthetase 9.9
tubulin-tyrosine ligase 9.9
progesterone receptor membrane component 2 9.9
Mad4 9.9
Argininosuccinate synthetase 9.8
CFHR2 9.7
MYBBP1A 9.7
ID2 9.7
GCPS 9.5
TMEM70 9.5
biotin carboxylase 9.5
PSPH 9.4
betaine homocysteine methyltransferase 9.4
EURL 9.4
PRS2 9.3
GMPS 9.3
CTP synthetase 9.3
AIM-1 9.3
CED-5 9.3
ASS1 9.2
EPH receptor A2 9.2
4'-phosphopantetheinyl transferase 9.2
amidophosphoribosyltransferase 9.1
GPX7 9.1
ATP synthase subunit beta 9.1
CA XIV 9.1
Cannabinoid receptor 1 9.0
CRN 9.0
GMP synthase 9.0
ugd 8.9
CA5 8.9
ribosomal protein S20 8.9
SECT 8.9
dihydroorotate dehydrogenase 8.9
ASS 8.9
L-glutaminase 8.8
B47 8.8
GGPPS 8.8
sarcosine dehydrogenase 8.8
Cytochrome P450 2C19 8.8
CA VII 8.8
cyclophilin 40 8.7
ornithine transcarbamylase 8.7
UMP synthase 8.7
PHGDH 8.7
proteasome subunit alpha 8.7
K74 8.7
LeuRS 8.6
BPX 8.6
K35 8.6
SPS 8.6
K37 8.6
phosphate-activated glutaminase 8.6
ACADM 8.6
Envelope protein 8.5
HARS 8.5
glutaminase 8.4
c-myb protein 8.4
AMSH 8.4
NP3 8.4
CTP synthase 8.3
N-MYC 8.3
LGS 8.3
NUC 8.2
uridine kinase 8.2
CCAT 8.2
EPS1 8.2
CHAD 8.2
ATP5B 8.1
calmodulin binding protein 8.1
annexin IV 8.1
DNA-directed RNA polymerase 8.1
hemoglobin beta 8.1
HHH 8.1
K40 8.1
HERA 8.0
P58 8.0
acidic mammalian chitinase 8.0
UPRT 8.0
endonuclease G 8.0
TFI 8.0
STAMP 8.0
CERT 8.0
4-aminobutyrate aminotransferase 8.0
GLUD1 8.0
PTPRD 7.9
CAD 7.8
PPT1 7.8
glutamine synthetase 7.8
UMP-CMP kinase 7.8
FMI 7.8
K79 7.8
thrombospondin-4 7.8
tRNase Z 7.7
Cystathionine gamma-lyase 7.7
sej 7.7
ribosomal protein S4 7.7
aminoacylase 7.7
phosphomevalonate kinase 7.7
K24 7.7
SGT 7.6
I-FABP 7.6
HSD-1 7.6
OPS 7.6
IMP 7.5
HMGR 7.5
K80 7.5
DSE 7.5
CPN 7.4
asparagine synthetase 7.4
SLB 7.4
S-adenosyl-L-homocysteine hydrolase 7.4
A-I 7.4
ASL 7.4
tryptophanyl-tRNA synthetase 7.4
pyrroline-5-carboxylate synthetase 7.3
Glutamine synthetase 7.3
BRE 7.3
NP2 7.3
DRP 7.3
4-hydroxyphenylpyruvate dioxygenase 7.2
DPP8 7.2
SGT1 7.2
ornithine aminotransferase 7.2
alanyl-tRNA synthetase 7.2
XMP 7.2
SIRT7 7.2
PTG 7.2
more...
Disease
CPS deficiency 11.4
Focal motor seizures 10.9
Galloway-Mowat syndrome 9.5
ring chromosome 20 9.3
Staphylococcal food poisoning 8.9
SPS 8.6
chest pain syndrome 8.6
hyperornithinemia 8.4
HHH 8.3
hyperargininemia 8.3
OPS 8.2
SPS 8.2
ornithine transcarbamylase deficiency 8.0
citrullinemia 7.9
Greig cephalopolysyndactyly syndrome 7.9
complex partial seizures 7.8
muscle swelling 7.7
hypopharyngeal squamous cell carcinoma 7.7
child neglect 7.4
FA2 7.4
LGS 7.3
HS3 7.2
Pel 7.0
global aphasia 7.0
photoallergy 7.0
Pfeiffer syndrome 7.0
liver infection 6.7
NPS 6.7
Enzyme inhibition 6.6
EPS 6.6
metastatic bladder cancer 6.5
AOS 6.4
EPS 6.4
Spraying 6.3
Shwartzman reaction 6.2
cancer relapse 6.2
hyperviscosity syndrome 6.1
multiple personality disorder 6.0
vasospastic angina 6.0
Neuromuscular blockade 5.9
RP11 5.9
DHS 5.9
furunculosis 5.9
HCI 5.8
DHS 5.8
child abuse 5.8
CP1 5.8
LMS 5.7
LMS 5.7
HHS 5.7
HHS 5.7
SLS 5.6
status asthmaticus 5.6
SLS 5.6
Chronic heart failure 5.5
scalded skin syndrome 5.5
IGS 5.5
hepatic coma 5.5
lobar pneumonia 5.5
Klebsiella 5.5
LIS1 5.4
MLS 5.4
recurrent ovarian cancer 5.4
kidney tumor 5.4
NMS 5.4
atypical pneumonia 5.3
Farber 5.3
psychopathy 5.2
chest infection 5.2
inflammatory breast cancer 5.2
CFD 5.2
Crouzon syndrome 5.2
PKS 5.1
erythroblastosis 5.1
Apert syndrome 5.1
COL2A1 5.1
RTS 5.0
CLN3 5.0
Lesch-Nyhan syndrome 4.9
chronic cholecystitis 4.9
CHARGE syndrome 4.9
Lennox-Gastaut syndrome 4.9
Reye's syndrome 4.8
rind 4.8
Hermansky-Pudlak syndrome 4.8
malignant ascites 4.8
SCS 4.8
NMS 4.8
GBS 4.8
small lymphocytic lymphoma 4.7
LMS 4.7
CIE 4.7
zygomycosis 4.7
Proteus 4.6
coxarthrosis 4.6
coronary artery disease 4.6
hysteria 4.5
chronic persistent hepatitis 4.5
Q fever 4.5
herniated disc 4.5
scrub typhus 4.5
EL4 4.4
CHS 4.4
febrile convulsions 4.4
sexual abuse 4.4
liver abscess 4.3
Frey 4.3
GPS 4.2
otosclerosis 4.2
hygroma 4.2
Pulmonary arterial hypertension 4.2
CES 4.1
alcoholic hepatitis 4.1
DES 4.1
respiratory acidosis 4.1
gallbladder cancer 4.0
nephrosis 4.0
MAS 4.0
PGA 4.0
scabies 4.0
Chronic kidney disease (CKD) 4.0
otitis 4.0
colibacillosis 3.9
domestic violence 3.9
metabolic alkalosis 3.9
PCL 3.9
EDC 3.9
tumor initiation 3.8
sensory neuropathy 3.8
Dissociation 3.7
learning disability 3.7
premenstrual syndrome 3.7
lymphoblastic leukemia 3.7
coma 3.7
staphylococcus 3.7
follicular lymphoma 3.7
LCA 3.7
antisocial behavior 3.6
melioidosis 3.6
temporal lobe epilepsy 3.6
Autism spectrum disorder 3.6
tetanus 3.6
mucormycosis 3.6
MLC 3.6
conduct disorder 3.6
biliary atresia 3.5
precocious puberty 3.5
fecal incontinence 3.5
varicocele 3.5
optic atrophy 3.5
ICH 3.5
cor pulmonale 3.5
alkalosis 3.5
ICC 3.5
drug withdrawal 3.4
carpal tunnel syndrome 3.4
ICC 3.4
cryptosporidiosis 3.4
panic attacks 3.4
catalepsy 3.4
more...
Symptom
partial seizure 6.2
tonic-clonic seizure 5.3
leg edema 5.2
Sedation 4.2
Neuropathic pain 4.2
despair 4.0
starvation 3.7
Depressive symptoms 3.7
asthenia 3.3
seizures 3.2
hypotonia 3.1
spasm 2.8
acute pain 2.7
acute stress 2.4
hyperoxia 2.3
hepatomegaly 2.1
flushing 2.0
anorexia 1.9
ataxia 1.7
distraction 1.4
nausea and vomiting 1.4
splenomegaly 1.4
insomnia 1.3
agitation 1.1
stigma 0.9
functional recovery 0.9
exhaustion 0.9
analgesia 0.8
chest pain 0.5
diarrhea 0.4
pain 0.1
anesthesia -0.1
dyspnea -0.2
weakness -0.6
fatigue -1.0
Drug
Saforide 12.3
Argininosuccinate 11.5
Remacemide hydrochloride 10.6
ID2 9.6
E5564 9.5
Parsol 9.4
Kayexalate 9.3
Posilac 9.3
Eucalyptus oil 9.2
Diltiazem hydrochloride 9.0
OTC 8.6
OTC 8.0
TPV 7.8
Pyridoxal phosphate 7.5
OMP 7.3
CED 7.0
Diamminedichloroplatinum 6.9
Cytidine 6.8
Rasburicase 6.6
CPO 6.4
Triad 6.3
CPZ 6.3
NH3 6.3
Triad 6.2
Enrofloxacin 6.2
CDP 5.8
Vicryl 5.6
NAG 5.5
CPM 5.4
Glycerol 5.0
Bupivacaine 5.0
Adenosine triphosphate 4.8
Methylprednisolone 4.8
Oxaliplatin 4.8
Prednisone 4.6
PFA 4.6
Infliximab 4.5
Infliximab 4.5
AMC 4.4
Aloe 4.4
CoCl2 4.3
CoCl2 4.3
Alanine 4.2
CPR 3.9
NaI 3.8
NaI 3.8
NaI 3.8
NaI 3.8
Glucagon 3.8
ACT 3.5
MDS 3.5
TAT 3.4
pyridoxal phosphate 3.3
Fraction 3.3
ETS 3.3
AZT 3.2
DNase I 3.2
Mutagen 3.1
Gel 3.1
AZT 3.1
Taxol 3.0
CTX 2.9
p75 2.7
Spectrum 2.7
Spectrum 2.6
lactose 2.6
ascorbate 2.5
ROS 2.4
Ethanol 2.4
citric acid 2.4
ampicillin 2.2
CAM 2.1
vitamin E 2.1
Asn 2.1
CaCl2 2.0
CaCl2 2.0
CaCl2 1.9
ZnO 1.9
lysine 1.8
ABC 1.5
Leaf 1.2
NADH 1.2
TiO2 1.2
MAP 0.7
Monit 0.5
caffeine 0.2
IL-2 -0.2
Cardiovasc -0.7
Dermatol -3.4
Enzyme
CPS 14.6
1,2-diacylglycerol 3-glucosyltransferase 12.6
dihydroorotase 12.6
sedoheptulokinase 12.3
carbamoylphosphate synthetase 11.9
serine dehydrogenase 11.6
ent-kaurene synthase 11.6
aspartate transcarbamylase 11.5
malate thiokinase 11.3
phosphoenolpyruvate-protein phosphotransferase 11.2
carbamate kinase 11.1
N-acetylglutamate synthase 10.9
N-acetylglutamate synthase 10.6
CPA2 10.4
acetylornithinase 10.3
N-acetylglutamate kinase 10.3
ornithine transcarbamylase 10.1
amidophosphoribosyltransferase 10.0
copalyl diphosphate synthase 10.0
argininosuccinate synthetase 9.9
argininosuccinate lyase 9.9
L-asparagine synthetase 9.8
biotin carboxylase 9.8
GMP synthetase 9.7
tubulin-tyrosine ligase 9.7
methylmalonate-semialdehyde dehydrogenase 9.7
ent-copalyl diphosphate synthase 9.5
alpha-galactosyltransferase 9.3
acetylornithine aminotransferase 9.3
uracil phosphoribosyltransferase 9.3
orotidine-5'-phosphate decarboxylase 9.0
dihydrodipicolinate reductase 9.0
dihydroorotate dehydrogenase 9.0
dihydroorotate dehydrogenase 9.0
methylglyoxal synthase 8.9
GMP synthase 8.8
orotate phosphoribosyltransferase 8.8
sarcosine dehydrogenase 8.8
allantoicase 8.8
enzyme X 8.8
MetE 8.7
GSase 8.6
D-alanine:D-alanine ligase 8.6
dihydrolipoamide succinyltransferase 8.5
amorpha-4,11-diene synthase 8.5
UMP kinase 8.4
carboxypeptidase S 8.4
glutaminase 8.4
arginase 8.3
SPS 8.3
homocysteine methyltransferase 8.2
cystathionine gamma-synthase 8.1
EC 2.6.1.16 8.1
thymidylate kinase 8.0
uridine kinase 7.9
adenylosuccinate synthetase 7.9
CAD 7.8
transcarboxylase 7.8
CAD 7.8
glutamine synthetase 7.8
CAD 7.8
Escherichia coli exonuclease III 7.7
CTP synthase 7.7
allantoinase 7.7
tRNase Z 7.6
pyruvate oxidase 7.6
pyruvate oxidase 7.5
glycinamide ribonucleotide transformylase 7.4
SLB 7.4
lipoate acetyltransferase 7.4
endoproteinase Asp-N 7.4
lactase-phlorizin hydrolase 7.3
tryptophanyl-tRNA synthetase 7.3
asparagine synthetase 7.2
oxaloacetate decarboxylase 7.2
tryptophan synthase 7.2
pyruvate carboxylase 7.2
dCMP deaminase 7.2
ornithine aminotransferase 7.1
adenylosuccinate lyase 7.1
glutamate synthase 7.0
glutamate synthase 7.0
PFI 7.0
glutamate synthase 7.0
lactase-phlorizin hydrolase 6.9
phosphocholine cytidylyltransferase 6.9
alanyl-tRNA synthetase 6.9
glutamic dehydrogenase 6.8
4-hydroxyphenylpyruvate dioxygenase 6.8
PRPP synthetase 6.7
glutamate dehydrogenase 6.7
glutamate dehydrogenase 6.7
glutamate dehydrogenase 6.7
isoleucyl-tRNA synthetase 6.7
tyrosine aminotransferase 6.6
condensing enzyme 6.6
S-adenosyl-L-homocysteine hydrolase 6.5
conjugase 6.5
LuxS 6.4
leucyl-tRNA synthetase 6.4
acylase 6.4
levansucrase 6.3
anthranilate synthase 6.2
reductoisomerase 6.1
beta-hydroxybutyrate dehydrogenase 6.1
SNO 6.0
phosphoenolpyruvate carboxykinase 6.0
3'-exonuclease 6.0
succinyl-CoA synthetase 5.9
phosphoenolpyruvate carboxykinase 5.9
endoproteinase Glu-C 5.9
phosphoenolpyruvate carboxykinase 5.9
arginine deiminase 5.9
CPN 5.9
STK11 5.8
acetate kinase 5.7
6-phosphogluconate dehydrogenase 5.7
6-phosphogluconate dehydrogenase 5.7
SCS 5.6
cystathionine gamma-lyase 5.6
fumarase 5.5
phosphoenolpyruvate carboxylase 5.5
glucokinase 5.5
serine hydroxymethyltransferase 5.4
glucose-6-phosphatase 5.4
arginine decarboxylase 5.3
arylsulfatase A 5.3
cysteine synthase 5.3
factor C 5.3
CPM 5.2
3-hydroxyacyl-CoA dehydrogenase 5.2
glutathione synthetase 5.2
3-hydroxyacyl-CoA dehydrogenase 5.2
methionine adenosyltransferase 5.2
AMP deaminase 5.2
acetyl-CoA carboxylase 5.1
glycerol kinase 5.1
lactic acid dehydrogenase 5.0
manganese peroxidase 5.0
peptidyl-prolyl cis-trans isomerase 5.0
acyl-CoA dehydrogenase 5.0
GABA transaminase 5.0
elastase 4.9
methionine synthase 4.9
carbonic anhydrase 4.9
acyl-CoA synthetase 4.9
deaminase 4.9
aconitase 4.8
sucrase-isomaltase 4.8
LasR 4.8
thymidylate synthase 4.8
IMP dehydrogenase 4.8
methionine synthase 4.8
mannanase 4.7
GAS 4.7
cystathionine beta-synthase 4.7
cytidine deaminase 4.7
farnesyltransferase 4.6
ECH 4.6
lactase 4.6
more...
Compound
acetylglutamate 12.2
Acivicin 11.3
Argininosuccinate 11.1
carbamyl phosphate 11.1
6-Azauridine 10.5
Canaline 10.5
Adipic acid dihydrazide 10.3
UMP 9.6
Ornithine 9.1
ornithine 8.9
ornithine 8.9
ornithine 8.9
ornithine 8.9
ornithine 8.9
CZP 8.9
PRPP 8.8
PALA 8.6
Carbamate 8.5
Triethylamine 8.3
6-APA 8.2
mercaptopyruvate 8.2
FMI 8.1
Tiazofurin 8.0
Diamminedichloroplatinum 7.8
dUDP 7.7
O,O-diethyl 7.7
dADP 7.6
norvaline 7.5
UTP 7.5
IMP 7.5
norvaline 7.4
C 6 7.4
pyrimidine 7.4
pyrimidine 7.3
XMP 7.3
OMP 7.2
Cyd 7.2
carbamic acid 7.2
Glutamine 7.1
glutamine 7.1
DSE 7.1
PMP 7.1
PMP 7.0
PMP 6.9
Methyl jasmonate 6.9
Foscarnet 6.8
SP-1 6.8
Pyrrolizidine 6.8
Elan 6.8
PMB 6.7
ammonia 6.7
Reserpine 6.6
HBC 6.6
CPH 6.6
Beryllium 6.6
DDM 6.5
Valinomycin 6.4
pyrroline-5-carboxylate 6.4
Pyrimethamine 6.3
Dextromethorphan 6.3
Leflunomide 6.3
CDP 6.3
Chondroitin 6.3
ORO 6.2
CTP 6.2
urea 6.2
CPZ 6.1
Safranin O 6.1
HEI 6.1
Carnitine 6.0
CIT 6.0
Uridine 6.0
7-methylguanosine 6.0
GA3 6.0
CsI 5.9
Dibutyryl cyclic AMP 5.8
Dibutyryl cyclic AMP 5.8
uridine 5.8
DTP 5.8
Jasmonic acid 5.8
itaconic acid 5.7
GA1 5.7
Tanshinone 5.6
6-phosphogluconate 5.6
CPA 5.6
L-carnitine 5.5
CPA 5.5
Organon 5.5
CPA 5.4
ECS 5.4
HCI 5.4
HCO 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.4
carbonic acid 5.3
Match 5.3
carbonic acid 5.3
UDP-glucose 5.2
Agar 5.2
CPA 5.2
UDP 5.2
ATC 5.1
UDP-galactose 5.1
Uracil 5.1
RELA 5.1
Chlorpyrifos 5.1
Bupivacaine 5.1
ATC 5.0
AFC 5.0
MPC 5.0
DON 5.0
triethoxysilane 5.0
heptose 5.0
heptose 5.0
heptose 5.0
benzenesulfonamide 4.9
benzenesulfonamide 4.9
benzenesulfonamide 4.9
HfO2 4.9
Biotin 4.9
Methylprednisolone 4.9
BAP 4.9
Acetazolamide 4.9
VM-26 4.9
AAT 4.9
carbonic acid 4.8
Capsaicin 4.8
PAP 4.8
acetyl-CoA 4.8
Ceftriaxone 4.8
MOP 4.7
MgCl2 4.7
arginine 4.7
Artemisinin 4.7
hippurate 4.6
Valproic acid 4.6
glutamate 4.6
carbonic acid 4.6
NH2 4.6
PAP 4.6
PAP 4.6
APS 4.6
UGA 4.6
Trypsin 4.5
HBr 4.5
phosphate 4.5
more...