Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.5.5 (CPS)
 1,262 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study evaluated the shear bond strength to enamel and dentin and bonding mechanism to dentin of Gluma CPS bonding system to primary teeth enamel and dentin. Pekafill hybrid composite was used. Ten specimens were immersed in deionized water at 37 degrees C for twenty-four hours and ten other specimens were subjected to a thermocycling procedure (2000 cycles between 5 degrees and 55 degrees C, dwell time fifteen seconds). After water storage or thermocycling, the bonded cylinders were sheared and the bond strength calculated. After debonding, the failure sites of all samples were evaluated microscopically. The data were analyzed with an ANOVA and Student-Newman-Keuls test. In ten other primary molars, the buccal surfaces were ground flat on wet SiC papers to expose peripheral dentin. Cylindrical buttjoint cavities were prepared with a cylindrical diamond bur. The cavities were treated with Gluma CPS and filled with pekafill as described above. After fifteen-minute water storage, filling excess was removed and marginal integrity and bonding mechanism of five restorations was examined with a light microscope. Five other restorations were evaluated after storage in water at 37 degrees C for twenty-four hours. Maximal gap widths and hybrid layer thickness were determined. The results showed that thermocycling did not affect the shear bond strength to enamel or dentin. There was a statistically significant difference (p < 0.05) between the shear bond strength values obtained in enamel and dentin. The maximal gap width was not significantly different between specimens that were stored in water for fifteen minutes or twenty-four hours. The average hybrid layer thickness was 11.7 +/- 1.1 micrograms. All specimens revealed a resin cohesive failure very close to enamel or dentin surface. The etch patterns produced on the abraded enamel surface were uniform and deeper as compared to the sample that was pumiced. This was also confirmed in the epoxy replicas.
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PMID:Enamel and dentin bond strength and bonding mechanism to dentin of Gluma CPS to primary teeth. 909 16

This study investigated the penetrability of dentinal tubules in cavity walls lined with different dentin bonding systems. Occlusal Class I cavities were prepared in 93 premolars. The cavities in the control group had an intact smear layer without a lining, while those in the experimental group were lined with Gluma CPS, Scotchbond Multi-Purpose Plus or One-Step. The penetrability of the dentinal tubules was tested with a dye (basic fuchsin) or bacteria (S faecalis) immediately after adhesive lining and after one-month storage in water at 37 degrees C. Some of the lined samples were sectioned and examined under the SEM. In some samples in the experimental group, the dye penetrated to the pulp and bacteria up to 125 microm into the dentinal tubules immediately after lining. The Kruskal Wallis ANOVA and Tukey test showed the depth of dye and bacterial penetration to be significantly less in teeth with bonding systems than those in the control group (p<0.05). However, there was no statistically significant difference between the control and experimental groups after storage in water (p>0.05). SEM examination showed that the hybrid layer and resin tags were present in the cavity walls immediately after lining but absent after storage in water. Therefore, adhesive linings under the experimental conditions were ineffective in preventing dye or bacterial penetration of the dentinal tubules.
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PMID:Penetrability of dentinal tubules in adhesive-lined cavity walls. 1193 Nov 34