Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.4.6 (urease)
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Human Gene/Protein
TAP binding protein 11.1
OR51B5 10.1
Allantoicase 10.1
ASB1 9.9
OHCU decarboxylase 9.7
Kangai 1 9.7
TJ6 9.6
Alkaline phosphomonoesterase 9.5
aquarius 9.5
TB3-1 9.5
EFG2 9.2
CD300E 9.1
HAO2 9.1
ASB3 8.9
CP11 8.7
KDEL receptor 1 8.7
mtRF1a 8.7
integral membrane protein 2A 8.7
PPHA 8.7
alkaline phosphomonoesterase 8.6
HLA-DRB1*0402 8.5
arylsulfatase 8.4
SAR1A 8.2
L-lactic dehydrogenase 8.1
TRIT1 8.1
beta-ureidopropionase 8.1
KAI1 protein 8.1
AK6 8.1
AGU 8.0
arylsulphatase 7.9
SLC14A1 7.9
AD 2 7.9
VPH1 7.8
ASB2 7.8
p62dok 7.7
beta-alanine synthase 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.7
CL-6 7.7
selD 7.7
SS1 7.6
UDP-N-acetylglucosamine pyrophosphorylase 7.5
ITSN 7.5
IPK1 7.4
tubulin-tyrosine ligase 7.4
MND1 7.4
transcription regulator protein 7.3
TAP2B 7.3
Selenophosphate synthetase 7.3
histidase 7.3
K72 7.3
L-glutaminase 7.3
ALC 7.2
LIME 7.2
Cysteine-rich intestinal protein 7.1
CHOD 7.1
acetaldehyde dehydrogenase 2 7.1
cysteinyl-tRNA synthetase 7.1
ASP1 7.1
MINCLE 7.1
GDH2 7.1
SALL2 7.0
TOPORS 7.0
N-acetylglutamate synthetase 7.0
glucosidase 6.9
D123 6.9
SEC6 6.9
soluble liver antigen 6.9
ITSN1 6.9
K26 6.9
AK4 6.9
DCD 6.9
PDE7B 6.8
HG3 6.8
CFBP 6.8
EB-1 6.8
lipoxygenase-3 6.8
phosphomonoesterase 6.7
melanoregulin 6.7
ORF-3 6.7
TIFA 6.6
more...
Disease
Helicobacter-associated disease 11.1
Cervical Carcinoma 10.1
Chronic antral gastritis 9.7
Chronic superficial gastritis 9.7
Vestibular vertigo 9.2
Gastric infection 9.2
tyrosinuria 9.2
Superficial gastritis 9.2
urethrolithiasis 9.1
H pylori infection 8.9
Disseminated trichosporonosis 8.9
Proteus mirabilis infection 8.7
alcoholic gastritis 8.6
Helicobacter pylori infection 8.4
gastric mucosal atrophy 8.4
Chronic gastritis 8.3
Erosive esophagitis 8.2
gastritis 8.1
galactosuria 7.7
Brunner's gland hyperplasia 7.7
antritis 7.6
Ureaplasma infection 7.5
duodenitis 7.4
GUD 7.4
Upper gastrointestinal symptoms 7.4
Pulmonary coccidioidomycosis 7.4
acute gastritis 7.3
peptic ulcer 7.3
dyspepsia 7.2
bartholinitis 7.2
gastroduodenitis 7.2
Helicobacter pylori gastritis 7.2
orotic aciduria 7.1
Gastric lymphoma 7.1
duodenal ulcer 7.1
Proteus 7.1
TBCD 7.1
gastric ulcer 6.6
Digestive Diseases 6.6
OCM 6.6
Portal hypertensive gastropathy 6.5
TDD 6.5
atrophic gastritis 6.4
AOA 6.4
Supragingival plaque 6.4
tinea corporis 6.4
Disseminated cryptococcosis 6.3
chronic laryngitis 6.3
Pulmonary sarcoidosis 6.2
Diaper dermatitis 6.2
Stomach 6.2
mucosa-associated lymphoid tissue 6.1
Biotin deficiency 6.1
gastric neoplasm 6.0
onychogryphosis 6.0
pyelitis 5.9
urolithiasis 5.9
Bacterial sepsis 5.9
AA2 5.9
Stomach 5.9
Stomach 5.9
Stomach 5.9
hyperornithinemia 5.8
pH increased 5.8
rat-bite fever 5.8
cystinuria 5.8
infectious meningitis 5.8
nail infection 5.7
Other variants 5.7
functional diarrhea 5.7
propionic acidemia 5.6
HSAN 5.6
Gastric outlet obstruction 5.6
vascular rupture 5.5
CTPA 5.5
hyperprolinemia 5.5
Phaeohyphomycosis 5.5
AGS 5.4
mesenteric lymphadenitis 5.4
chronic urinary tract infection 5.4
more...
Symptom
Cloudy urine 10.1
Gastrointestinal distress 8.5
skin impairment 7.6
epigastric distress 6.5
Blanching 5.3
acid regurgitation 4.7
belching 4.4
acidity 4.1
epigastric pain 4.0
consciousness disturbance 4.0
forgetfulness 3.7
eds 3.6
heartburn 3.3
stomach pain 3.1
twitching 3.1
Gastrointestinal symptoms 2.9
pleuritic chest pain 2.9
neck stiffness 2.8
abdominal pain 2.5
intestinal bleeding 2.4
rigors 2.4
general problem 2.3
erythema 2.1
microbial colonization 2.0
Hudson 2.0
flank pain 2.0
agitation 2.0
productive cough 1.9
hypoproteinemia 1.9
lethargy 1.9
hypertonia 1.8
tachypnea 1.7
diarrhea 1.7
Wind 1.7
starvation 1.7
nasal discharge 1.6
vomiting 1.5
bloating 1.3
oliguria 1.2
nausea 1.1
acute abdominal pain 1.1
fever of unknown origin 1.0
polydipsia 0.9
dysuria 0.8
sore throat 0.6
shoulder pain 0.6
discomfort 0.6
hoarseness 0.5
HSA 0.5
discomfort 0.5
polyuria 0.5
tremor 0.5
colic 0.4
flushing 0.4
anorexia 0.3
vertigo 0.3
collapse 0.2
acute pain 0.1
regurgitation 0.0
chills -0.0
paresthesia -0.2
Ill -0.4
thinning -0.4
hepatomegaly -0.4
hypotonia -0.5
back pain -0.5
tinnitus -0.6
cough -0.9
weakness -1.2
dizziness -1.2
splenomegaly -1.2
constipation -1.3
headache -1.4
sleepiness -1.6
dyspnea -1.7
ataxia -1.9
pain -2.0
overweight -2.6
seizures -3.2
fatigue -3.6
more...
Drug
Calcibind 12.1
Lithostat 12.1
Ammonia water 10.1
Troxipide 9.5
Ecabet sodium 8.6
Oyster shell 8.6
Ranitidine bismuth citrate 8.4
Whole human blood 7.8
Potassium citrate 7.4
H2SeO3 7.2
Moco 7.1
Zithromax 7.1
monobasic sodium phosphate 7.0
Hoelen 6.7
Optison 6.5
Orion 6.3
Omeprazole 6.3
Fenoprofen 6.1
Rize 6.1
Dextran sulfate sodium 6.0
Optison 5.9
Sterile water 5.9
NH3 5.8
AraC 5.7
Amoxicillin 5.7
Rasburicase 5.7
L-Asparaginase 5.6
EMB 5.6
Guar gum 5.5
Sodium benzoate 5.4
Cellulase 5.4
Tween 60 5.4
Ammonium chloride 5.2
Geranium 5.0
Tinidazole 5.0
beta-Galactosidase 4.9
Soybean oil 4.8
Nitazoxanide 4.8
AGG 4.7
SrCl2 4.7
AMC 4.7
CAZ 4.6
Serum albumin 4.6
SrCl2 4.5
lactose 4.5
Dextrose 4.4
niacin 4.4
Rifaximin 4.4
Xylocaine 4.3
MEA 4.3
Gastro 4.2
OMP 4.2
Ginger 4.2
CEC 4.2
Sodium alginate 4.1
Indinavir 4.1
Asparaginase 4.0
Xylocaine 4.0
Levovist 4.0
Furan 3.9
CER 3.9
Papain 3.9
Lactose 3.9
Bestatin 3.9
Bifidobacterium 3.9
CPO 3.8
Senna 3.8
Sumatran 3.8
Fipronil 3.8
Senna 3.7
Guanidine 3.7
Guanidine 3.6
Xylocaine 3.6
Gelatin 3.6
ampicillin 3.5
Cantor 3.5
CTT 3.4
Hyaluronidase 3.2
ISP 3.2
Emodin 3.2
more...
Enzyme
urease 12.1
methylenediurease 12.1
urease 12.1
EC 3.5.3.2 11.1
allophanate hydrolase 10.9
ureidoglycolate lyase 10.5
hydantoin hydrolase 10.5
geranoyl-CoA carboxylase 10.1
urethanase 10.1
EC 2.6.1.14 10.1
ureidoglycolate hydrolase 10.1
allantoate amidohydrolase 10.0
allantoicase 9.9
allantoinase 9.6
N-methylhydantoin amidohydrolase 9.5
imidazolonepropionase 9.2
formamidase 9.0
AtzB 8.9
lysine decarboxylase 8.7
citrulline ureidase 8.7
malate thiokinase 8.7
AtzC 8.6
phosphoglucosamine mutase 8.5
lactate racemase 8.4
nicotinamidase 8.3
creatininase 8.2
4-hydroxybenzoate 3-monooxygenase 8.1
leucine dehydrogenase 8.0
arginine deiminase 8.0
tRNA isopentenyltransferase 8.0
invertase 7.9
decarbonylase 7.9
UDP-N-acetylglucosamine pyrophosphorylase 7.8
omega-amidase 7.8
arylsulfatase 7.8
beta-ureidopropionase 7.7
acetone carboxylase 7.7
creatinase 7.7
creatinine iminohydrolase 7.7
EC 1.1.1.47 7.6
N-acetylglucosamine-6-phosphate deacetylase 7.6
imidase 7.4
cysteinyl-tRNA synthetase 7.2
histidase 7.2
tubulin-tyrosine ligase 7.1
IgA protease 7.1
sucrase 7.1
hydroxylamine reductase 7.1
aryl-alcohol dehydrogenase 7.1
hydroxylamine reductase 7.1
beta-glucosidase 7.0
tryptophanase 6.9
atrazine chlorohydrolase 6.9
beta-glucosidase 6.8
biotin carboxylase 6.8
phosphoamidase 6.8
carbamate kinase 6.7
alanine aminopeptidase 6.7
nitrate reductase 6.7
methyl coenzyme M reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.7
nitrate reductase 6.6
ornithine cyclodeaminase 6.6
methylcrotonyl-CoA carboxylase 6.5
hydrogenase 6.5
hydrogenase 6.5
sulfatase 6.5
uricase 6.5
arginase 6.5
glycine reductase 6.4
mutanase 6.4
hyaluronate lyase 6.3
IgA1 protease 6.3
phosphoribosylanthranilate isomerase 6.3
TDH 6.3
dihydropyrimidinase 6.3
FTR 6.2
more...
Compound
N-Benzylaniline 12.1
Benurestat 12.1
ethyl hentriacontanoate 12.1
(3,4-dichlorophenyl)acetic acid 12.1
Flurofamide 11.7
3-methylbenzohydrazide 11.5
Meralluride 11.1
Meralluride 11.1
methyl triacontanoate 11.1
Polypodine B 11.1
o-Cresolphthalein complexone 10.5
methyl 3,4,5-trihydroxybenzoate 10.5
Oxaluric acid 10.5
cis-Urocanic acid 10.3
ureidoglycolate 10.1
4-bromophenylboronic acid 10.1
Carfentrazone-ethyl 10.1
2-cyclohepten-1-one 10.1
Evernic acid 10.1
2-hydroxy-1-phenylethanone 9.7
1,3,4-thiadiazole-2(3H)-thione 9.7
5-Nitroimidazole 9.7
4-methoxybenzohydrazide 9.5
Nonactin 9.5
1,2,4-butanetricarboxylic acid 9.5
4-chlorobenzenesulfonyl chloride 9.5
Bromothymol blue 9.5
C6Cl4O2 9.5
allantoate 9.2
methyl 3,4,5-trihydroxybenzoate 9.1
Remin 9.1
2-hydroxy-1-phenylethanone 8.7
Poncirin 8.7
C6H10O4 8.7
2-imidazolidinimine 8.6
2-imidazolidinimine 8.6
Methylcitric acid 8.6
2-formylbenzoic acid 8.5
4-hydroxyphenyl acetate 8.4
2-methyl-1H-benzimidazole 8.4
Esculin 8.4
CDMT 8.4
4-fluorobenzamide 8.2
Dicyandiamide 8.1
Pretilachlor 8.1
1H-pyrazole-1-carbothioamide 8.1
Benzohydroxamic acid 8.1
Rabeprazole sodium 8.0
1-triacontanol 8.0
C2H5NO2 7.9
Hydroxyatrazine 7.9
2-octenoic acid 7.7
1-naphthalenesulfonic acid 7.7
1-naphthalenesulfonic acid 7.7
N,N-dimethylurea 7.7
selenic acid 7.6
selenic acid 7.6
Triphenylmethane 7.6
selenic acid 7.6
Brilliant Yellow 7.5
3-methylpiperidine 7.5
3-methylpiperidine 7.5
Urocanic acid 7.5
L-749 7.4
hydrazinecarboxamide 7.4
nicotinohydrazide 7.2
3-hydroxyhexadecanoic acid 7.2
2-piperidinone 7.1
2-hydroxy-4-methoxybenzaldehyde 7.1
Lansoprazole 7.1
urea 7.0
diphenylacetic acid 7.0
Flavomycin 7.0
Tuberculostearic acid 7.0
Patchouli alcohol 7.0
Canavanine 6.9
URP 6.9
Bronopol 6.8
1-phenyl-1,2-propanedione 6.8
ReSe2 6.8
more...