Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.4.6 (urease)
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Human Gene/Protein
TAP binding protein 11.1
OR51B5 10.1
Allantoicase 10.1
ASB1 9.9
Kangai 1 9.7
OHCU decarboxylase 9.7
TJ6 9.6
Alkaline phosphomonoesterase 9.5
TB3-1 9.5
aquarius 9.5
EFG2 9.2
HAO2 9.1
CD300E 9.1
ASB3 8.9
integral membrane protein 2A 8.7
mtRF1a 8.7
CP11 8.7
KDEL receptor 1 8.7
PPHA 8.7
alkaline phosphomonoesterase 8.6
HLA-DRB1*0402 8.5
arylsulfatase 8.4
SAR1A 8.2
TRIT1 8.1
L-lactic dehydrogenase 8.1
beta-ureidopropionase 8.1
KAI1 protein 8.1
AK6 8.1
AGU 8.0
arylsulphatase 7.9
SLC14A1 7.9
AD 2 7.9
ASB2 7.8
VPH1 7.8
p62dok 7.7
N-acetylglucosamine-6-phosphate deacetylase 7.7
beta-alanine synthase 7.7
selD 7.7
CL-6 7.7
SS1 7.6
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Disease
Helicobacter-associated disease 11.1
Cervical Carcinoma 10.1
Chronic antral gastritis 9.7
Chronic superficial gastritis 9.7
Vestibular vertigo 9.2
tyrosinuria 9.2
Superficial gastritis 9.2
Gastric infection 9.2
urethrolithiasis 9.1
H pylori infection 8.9
Disseminated trichosporonosis 8.9
Proteus mirabilis infection 8.7
alcoholic gastritis 8.6
Helicobacter pylori infection 8.4
gastric mucosal atrophy 8.4
Chronic gastritis 8.3
Erosive esophagitis 8.2
gastritis 8.1
galactosuria 7.7
Brunner's gland hyperplasia 7.7
antritis 7.6
Ureaplasma infection 7.5
GUD 7.4
duodenitis 7.4
Pulmonary coccidioidomycosis 7.4
Upper gastrointestinal symptoms 7.4
acute gastritis 7.3
peptic ulcer 7.3
dyspepsia 7.2
bartholinitis 7.2
gastroduodenitis 7.2
Helicobacter pylori gastritis 7.2
orotic aciduria 7.1
Gastric lymphoma 7.1
duodenal ulcer 7.1
Proteus 7.1
TBCD 7.1
gastric ulcer 6.6
Digestive Diseases 6.6
OCM 6.6
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Symptom
Cloudy urine 10.1
Gastrointestinal distress 8.5
skin impairment 7.6
epigastric distress 6.5
Blanching 5.3
acid regurgitation 4.7
belching 4.4
acidity 4.1
epigastric pain 4.0
consciousness disturbance 4.0
forgetfulness 3.7
eds 3.6
heartburn 3.3
stomach pain 3.1
twitching 3.1
Gastrointestinal symptoms 2.9
pleuritic chest pain 2.9
neck stiffness 2.8
abdominal pain 2.5
intestinal bleeding 2.4
rigors 2.4
general problem 2.3
erythema 2.1
microbial colonization 2.0
Hudson 2.0
flank pain 2.0
agitation 2.0
productive cough 1.9
hypoproteinemia 1.9
lethargy 1.9
hypertonia 1.8
tachypnea 1.7
diarrhea 1.7
Wind 1.7
starvation 1.7
nasal discharge 1.6
vomiting 1.5
bloating 1.3
oliguria 1.2
nausea 1.1
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Drug
Lithostat 12.1
Calcibind 12.1
Ammonia water 10.1
Troxipide 9.5
Ecabet sodium 8.6
Oyster shell 8.6
Ranitidine bismuth citrate 8.4
Whole human blood 7.8
Potassium citrate 7.4
H2SeO3 7.2
Moco 7.1
Zithromax 7.1
monobasic sodium phosphate 7.0
Hoelen 6.7
Optison 6.5
Orion 6.3
Omeprazole 6.3
Rize 6.1
Fenoprofen 6.1
Dextran sulfate sodium 6.0
Optison 5.9
Sterile water 5.9
NH3 5.8
AraC 5.7
Amoxicillin 5.7
Rasburicase 5.7
L-Asparaginase 5.6
EMB 5.6
Guar gum 5.5
Sodium benzoate 5.4
Cellulase 5.4
Tween 60 5.4
Ammonium chloride 5.2
Geranium 5.0
Tinidazole 5.0
beta-Galactosidase 4.9
Soybean oil 4.8
Nitazoxanide 4.8
AGG 4.7
SrCl2 4.7
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Enzyme
urease 12.1
methylenediurease 12.1
urease 12.1
EC 3.5.3.2 11.1
allophanate hydrolase 10.9
hydantoin hydrolase 10.5
ureidoglycolate lyase 10.5
ureidoglycolate hydrolase 10.1
geranoyl-CoA carboxylase 10.1
urethanase 10.1
EC 2.6.1.14 10.1
allantoate amidohydrolase 10.0
allantoicase 9.9
allantoinase 9.6
N-methylhydantoin amidohydrolase 9.5
imidazolonepropionase 9.2
formamidase 9.0
AtzB 8.9
lysine decarboxylase 8.7
malate thiokinase 8.7
citrulline ureidase 8.7
AtzC 8.6
phosphoglucosamine mutase 8.5
lactate racemase 8.4
nicotinamidase 8.3
creatininase 8.2
4-hydroxybenzoate 3-monooxygenase 8.1
leucine dehydrogenase 8.0
arginine deiminase 8.0
tRNA isopentenyltransferase 8.0
invertase 7.9
decarbonylase 7.9
UDP-N-acetylglucosamine pyrophosphorylase 7.8
omega-amidase 7.8
arylsulfatase 7.8
beta-ureidopropionase 7.7
acetone carboxylase 7.7
creatinase 7.7
creatinine iminohydrolase 7.7
EC 1.1.1.47 7.6
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Compound
(3,4-dichlorophenyl)acetic acid 12.1
Benurestat 12.1
ethyl hentriacontanoate 12.1
N-Benzylaniline 12.1
Flurofamide 11.7
3-methylbenzohydrazide 11.5
Polypodine B 11.1
Meralluride 11.1
methyl triacontanoate 11.1
Meralluride 11.1
methyl 3,4,5-trihydroxybenzoate 10.5
o-Cresolphthalein complexone 10.5
Oxaluric acid 10.5
cis-Urocanic acid 10.3
ureidoglycolate 10.1
2-cyclohepten-1-one 10.1
4-bromophenylboronic acid 10.1
Evernic acid 10.1
Carfentrazone-ethyl 10.1
2-hydroxy-1-phenylethanone 9.7
1,3,4-thiadiazole-2(3H)-thione 9.7
5-Nitroimidazole 9.7
Bromothymol blue 9.5
1,2,4-butanetricarboxylic acid 9.5
Nonactin 9.5
4-chlorobenzenesulfonyl chloride 9.5
C6Cl4O2 9.5
4-methoxybenzohydrazide 9.5
allantoate 9.2
Remin 9.1
methyl 3,4,5-trihydroxybenzoate 9.1
Poncirin 8.7
2-hydroxy-1-phenylethanone 8.7
C6H10O4 8.7
Methylcitric acid 8.6
2-imidazolidinimine 8.6
2-imidazolidinimine 8.6
2-formylbenzoic acid 8.5
2-methyl-1H-benzimidazole 8.4
4-hydroxyphenyl acetate 8.4
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