Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.4.6 (urease)
 7,490 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thalli of Evernia prunastri floated on 40 mM urea synthesize urease (EC3.5.1.5) which is, in part, retained in the cells as well as secreted into the external medium. By using [(14)C]urea, it has been shown that the (14)CO2 evolved by the action of urease is mainly incorporated into phenolic compounds. Evernic acid has the highest radioactivity when incubations are carried out in the light. The orsellinate moiety of this molecule contains ten times more radioactivity than the everninic acid moiety. This could be explained by the assumption that orsellinic acid is the first product of cyclisation of the polyketide chain in the biosynthetic pathway.
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PMID:The use of urea by Evernia prunastri thalli. 2425 63