Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.3.4.6 (
urease
)
7,490
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Ten new diterpene glycosides virescenosides Z
9
-Z
18
(
1
-
10
) together with three known analogues (
11
-
13
) and aglycon of virescenoside A (
14
) were isolated from the marine-derived fungus
Acremonium striatisporum
KMM 4401. These compounds were obtained by cultivating fungus on wort agar medium with the addition of potassium bromide. Structures of the isolated metabolites were established based on spectroscopic methods. The effects of some isolated glycosides and aglycons
15
-
18
on
urease
activity and regulation of Reactive Oxygen Species (ROS) and
Nitric Oxide
(NO) production in macrophages stimulated with lipopolysaccharide (LPC) were evaluated.
...
PMID:Virescenosides From the Holothurian-Associated Fungus
Acremonium Striatisporum
Kmm 4401. 3167 10
