Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.3 (glutathione synthetase)
 678 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
GSH synthetase 15.5
glutathione synthetase 15.1
Glutathione synthetase 14.8
gamma-glutamyl cyclotransferase 13.6
GSH2 13.5
5-oxoprolinase 13.3
GSH1 13.0
OPLAH 12.8
gamma-glutamylcysteine synthetase 12.5
GTR2 11.9
GLCLR 11.7
aromatic amino acid transporter 11.5
gamma-glutamylcyclotransferase 11.5
glutamate-cysteine ligase 11.3
ATG16L 11.3
GSS 11.2
HMT1 11.1
ERp18 11.1
GPX7 11.0
GSTA2-2 11.0
GCL 11.0
GSTM4 10.9
TNF-related apoptosis-inducing ligand receptor 2 10.9
GST2 10.9
tubulin-tyrosine ligase 10.8
aldehyde oxidase 1 10.8
SSAT1 10.8
peroxiredoxin 4 10.7
5-methyltetrahydrofolate-homocysteine methyltransferase 10.6
MAT2 10.6
riboflavin kinase 10.5
DNA damage-binding protein 2 10.5
PETA-3 10.4
biotin carboxylase 10.4
Glutamate-cysteine ligase 10.3
GSR 10.2
GST3 10.2
GAR transformylase 10.2
pristanoyl-CoA oxidase 10.2
GCLC 10.1
GCSh 10.1
GGCT 10.1
Rho GDP dissociation inhibitor alpha 10.1
maleylacetoacetate isomerase 10.0
GCS1 10.0
GSTZ1 10.0
GCLM 10.0
UDP-galactose-4-epimerase 10.0
adenosyltransferase 9.9
cysteine sulfinic acid decarboxylase 9.8
GCS 9.8
Pyruvate carboxylase 9.7
MsrB3 9.7
HBE1 9.6
peroxiredoxin 5 9.6
SEPT6 9.6
paraoxonase 2 9.5
SMYD2 9.5
NADP+-dependent isocitrate dehydrogenase 9.5
TNFSF13B 9.5
ARF7 9.5
pyrimidine 5'-nucleotidase 9.5
thioredoxin reductase 1 9.5
SELL 9.4
CDK3 9.4
copper transport protein 9.4
glutamate-cysteine ligase modifier subunit 9.4
UDP-N-acetylglucosamine pyrophosphorylase 9.4
CBX3 9.3
neutrophil protein 9.3
sulfate transporter 9.3
caveolin 3 9.3
choline dehydrogenase 9.3
ESM-1 9.3
cysteine desulfhydrase 9.2
FHL-1 9.2
LIV-1 9.2
GS-X 9.2
APS kinase 9.2
macrophage receptor with collagenous structure 9.2
more...
Disease
gamma-Glutamyl transpeptidase deficiency 15.5
Gamma-glutamylcysteine synthetase deficiency 15.5
5-Oxoprolinuria 14.9
5-Oxoprolinase deficiency 14.5
GCS1 9.9
Krabbe disease 8.7
gastric neoplasm 8.5
GSH 8.4
Tietze 7.7
drug-induced hepatitis 7.5
PARK7 7.5
RSI 7.5
hemolytic anemia 7.3
AIDS-related Kaposi's sarcoma 7.2
GCE 7.0
potassium deficiency 7.0
Tuberculous meningitis 7.0
chronic phase CML 7.0
bubonic plague 6.9
aminoaciduria 6.8
Familial hypercholesterolemia 6.7
homocystinuria 6.6
LMS 6.6
LMS 6.6
comedo 6.5
ATD 6.4
chlorosis 6.4
NCR 6.4
cystinosis 6.3
Focal segmental glomerulosclerosis 6.3
cystinuria 6.2
GSD 6.2
G6PD deficiency 6.1
PCS 6.0
Hepatotoxicity 6.0
recurrent cancer 5.9
Zellweger syndrome 5.9
galactosemia 5.9
CLN3 5.9
laryngeal squamous cell carcinoma 5.8
folate deficiency 5.8
kwashiorkor 5.8
LMS 5.6
PCC 5.6
cystoid macular edema 5.6
PAL 5.4
AGS 5.4
CHS 5.3
veno-occlusive disease 5.3
LTD 5.3
hereditary hemochromatosis 5.2
tubular necrosis 5.2
enzyme deficiency 5.1
neoplastic process 5.0
adenocarcinoma of the lung 4.9
AIN 4.9
Fanconi syndrome 4.8
Nonalcoholic fatty liver 4.8
cancer recurrence 4.7
hyperbilirubinemia 4.7
immunotoxicity 4.6
renal tubular acidosis 4.5
Fanconi 4.5
lactic acidosis 4.5
CEM 4.5
macular edema 4.5
WRN 4.4
enterocolitis 4.4
varicocele 4.4
MDS 4.3
pheochromocytoma 4.3
metabolic disorder 4.2
hypercalciuria 4.2
HSP 4.2
atrophic gastritis 4.2
African trypanosomiasis 4.0
genetic disorder 4.0
iron overload 3.9
hyperhomocysteinemia 3.8
lichen 3.8
more...
Symptom
Anoxia 6.4
chills 3.5
hepatosplenomegaly 3.4
ataxia 3.1
splenomegaly 2.3
acidity 1.6
starvation 0.9
collapse 0.7
abdominal pain 0.6
vomiting 0.6
diarrhea -0.3
seizures -0.8
pain -2.5
Drug
Indisulam 11.7
Bucillamine 10.2
Glutathione 9.8
Tiopronin 9.4
Trypanothione 8.6
Glucantime 7.6
Primaquine 7.6
Areca 7.4
Bestatin 7.4
Bortezomib 6.6
Xanthium 5.8
ascorbate 5.5
CoCl2 5.2
CoCl2 5.2
Arsenic trioxide 5.2
ZnCl2 5.2
ZnCl2 5.2
balanced salt solution 4.9
vitamin E 4.9
ROS 4.6
NAG 4.4
MDS 4.4
CDP 4.3
TAT 4.3
pyridoxal phosphate 4.2
Alanine 4.1
citric acid 3.3
Angiotensin II 3.2
NADH 3.1
THF 2.5
ABC 2.4
Ethanol 2.3
Asn 2.0
CSF 1.6
lysine 1.3
caffeine 1.1
Leaf 1.1
IL-2 0.7
Cardiovasc -2.1
Enzyme
glutathione synthetase 15.5
homoglutathione synthetase 14.7
5-oxoprolinase 13.0
gamma-glutamylcyclotransferase 12.5
gamma-glutamylcysteine synthetase 12.2
malate thiokinase 12.2
D-alanine:D-alanine ligase 12.1
phytochelatin synthase 11.5
D-cysteine desulfhydrase 11.5
cysteine synthase 10.9
biotin carboxylase 10.7
tubulin-tyrosine ligase 10.6
glycinamide ribonucleotide transformylase 10.3
ATP sulfurylase 10.0
ribulose 5-phosphate 3-epimerase 10.0
PAPS reductase 9.9
desulfhydrase 9.8
UDP-N-acetylglucosamine pyrophosphorylase 9.7
riboflavin kinase 9.5
serine acetyltransferase 9.4
threonine aldolase 9.3
dihydroxyacetone kinase 9.3
choline dehydrogenase 9.2
APS reductase 9.2
betaine-homocysteine methyltransferase 9.2
dehydroascorbate reductase 9.0
PTR1 8.8
glutathione reductase 8.8
sulfite reductase 8.7
sulfite reductase 8.7
sulfite reductase 8.7
polyphosphate kinase 8.7
APS kinase 8.7
LTC4 synthase 8.6
tripeptidase 8.5
succinyl-CoA synthetase 8.4
trehalose synthase 8.4
fumarylacetoacetate hydrolase 8.3
glycogenin 8.3
xylulokinase 8.1
cystathionine gamma-lyase 8.1
phospholipid hydroperoxide glutathione peroxidase 8.1
glucosidase II 8.0
adenylosuccinate lyase 8.0
cystathionine beta-synthase 7.9
betaine aldehyde dehydrogenase 7.9
pyridoxal kinase 7.7
cysteine dioxygenase 7.7
gamma-glutamyl transpeptidase 7.7
methionine adenosyltransferase 7.7
ADE2 7.7
acetate kinase 7.6
methionine sulfoxide reductase 7.6
SOR 7.6
formaldehyde dehydrogenase 7.6
glyoxalase II 7.6
xylitol dehydrogenase 7.4
biliverdin reductase 7.4
xylitol dehydrogenase 7.4
dimethylarginine dimethylaminohydrolase 7.3
carbamoylphosphate synthetase 7.2
inulinase 7.2
MsrA 7.2
spermidine synthase 7.1
SCS 7.1
trypanothione reductase 7.0
inulinase 7.0
glutathione peroxidase 6.9
ascorbate peroxidase 6.9
GLO 6.9
methionine synthase 6.8
MDP 6.7
methionine synthase 6.7
lactonase 6.7
polyamine oxidase 6.7
asparagine synthetase 6.6
arginine decarboxylase 6.5
CDH 6.4
serine hydroxymethyltransferase 6.3
heme oxygenase 6.3
more...
Compound
gamma-Glutamylcysteine 13.3
Ophthalmic acid 13.2
5-oxoproline 12.8
5-oxoproline 12.8
5-oxoproline 12.6
Methanofuran 12.5
5-oxoproline 12.3
3GC 12.1
Solasonine 12.1
L-Gulonolactone 10.9
2-AB 10.9
ECS 10.7
Buthionine sulfoximine 9.8
BSO 9.6
Carnosol 9.5
Isoproturon 9.5
TBHQ 9.2
O-acetylserine 9.0
O-acetylserine 8.8
Ethacrynic acid 8.8
Triphosphate 8.6
GSH 8.5
GSH 8.5
Ethacrynic acid 8.4
BNPP 8.4
GSSG 8.4
Chlorothalonil 8.4
O-acetylserine 8.4
Cys-Gly 8.2
isopropylbenzene 8.0
Monocrotaline 8.0
Fucoxanthin 8.0
Arecoline 7.8
Jasmonic acid 7.7
2-oxobutyrate 7.6
Primaquine 7.6
SKF 525A 7.5
Nitrofurantoin 7.3
LTA4 7.3
2-oxobutyrate 7.3
Bestatin 7.1
Safranin O 7.0
NOXA 7.0
Cysteine 6.8
norvaline 6.8
DDC 6.8
DDC 6.8
norvaline 6.7
dimethylarsinic acid 6.6
dimethylarsinic acid 6.6
dimethylarsinic acid 6.6
dimethylarsinic acid 6.6
D-Ala 6.6
dimethylarsinic acid 6.6
Imidacloprid 6.6
cysteine 6.5
Arsenate 6.5
BHC 6.5
ASN 6.5
DNFB 6.5
Cysteamine 6.5
dimethylarsinic acid 6.4
Glu-Glu 6.4
carbamyl phosphate 6.4
Arsenite 6.3
Safranin O 6.2
CDH 6.2
Methylglyoxal 6.1
Luteolin 6.1
Dichloroacetate 6.1
bromobenzene 6.1
APS 6.0
CdCl2 6.0
Polyamine 6.0
Epigallocatechin 5.9
N-acetylcysteine 5.9
DON 5.9
tert-butyl hydroperoxide 5.9
isobutyric acid 5.8
DDC 5.7
more...