Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.3 (glutathione synthetase)
 678 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glutathione synthetase 510
GSH 273
GSH synthetase 172
gamma-glutamylcysteine synthetase 115
glutathione reductase 89
ATP 72
catalase 58
Sep 57
glutathione peroxidase 53
Mol 52
superoxide dismutase 51
Glutathione synthetase 26
GSH2 26
glutathione S-transferase 26
glutamate-cysteine ligase 26
GCS 25
gamma-glutamyl transpeptidase 24
GSH1 22
GSR 21
Nrf2 18
reductase 16
SOD 15
5-oxoprolinase 15
erythroid 14
caspase-3 14
NADPH 14
heme oxygenase-1 13
ADP 13
thioredoxin 12
GSS 12
NAD 11
GCL 11
GCLC 10
metallothionein 10
ROS 10
gamma-glutamyltranspeptidase 8
biotin carboxylase 8
DT-diaphorase 8
p53 8
microsomal 8
superoxide dismutase 1 7
gamma-glutamyl cyclotransferase 7
peroxidase 7
glucose-6-phosphate dehydrogenase 7
insulin 7
AP-1 7
PCC 6
NQO1 6
glutaredoxin 6
Pyruvate carboxylase 6
p38 6
c-Jun 6
p65 6
GCLM 6
glutathione peroxidase 4 6
SDS 5
cytokine 5
GTG 5
MAPK 5
manganese superoxide dismutase 5
polypeptide 5
ATPase 5
nitric oxide synthase 5
hemoglobin 5
SOD2 5
glyoxalase I 4
apolipoprotein E 4
PC3 4
NADH 4
glutathione peroxidase 1 4
fused 4
pyruvate kinase 4
NMR 4
HO-1 4
MnSOD 4
lactate dehydrogenase 4
pyruvate dehydrogenase 4
PC2 4
alanine aminotransferase 4
multidrug resistance-associated protein 3
more...
Disease
GSH 273
cancer 33
hemolytic anemia 26
tumor 22
Alzheimer's disease 12
Krabbe disease 11
5-Oxoprolinuria 8
hepatocellular carcinoma 8
cold 7
HIV 6
pheochromocytoma 6
PCC 6
SDS 5
leukemia 5
cataract 5
diabetes 5
neuroblastoma 4
chlorosis 4
multiple sclerosis 4
anemia 4
liver disease 4
sepsis 4
sepsis 4
carcinoma 4
malnutrition 4
genetic disorder 3
infectious diseases 3
GCE 3
amyotrophic lateral sclerosis 3
glioma 3
AIDS 3
immunodeficiency 3
malaria 3
prostate cancer 3
Parkinson's disease 2
colon cancer 2
folate deficiency 2
colorectal cancer 2
hyperbilirubinemia 2
primary tumor 2
ATM 2
rheumatoid arthritis 2
macular degeneration 2
NAME 2
Familial hypercholesterolemia 2
Mycobacterium 2
homocystinuria 2
lactic acidosis 2
Blocking 2
metabolic syndrome 2
metabolic disorder 2
obesity 2
iron overload 2
neutropenia 2
carcinogenesis 2
gamma-Glutamyl transpeptidase deficiency 2
AGS 2
G6PD deficiency 2
influenza 2
tumor growth 2
Nonalcoholic fatty liver 2
Fanconi 2
ischemia 2
CEM 2
gastric cancer 2
tuberculosis 2
periodontitis 1
liver cancer 1
breast cancer 1
peripheral neuropathy 1
Leukemia 1
hypertension 1
dental caries 1
cirrhosis 1
alcohol abuse 1
Tuberculous meningitis 1
cornea 1
lichen 1
fatty liver 1
schizophrenia 1
more...
Symptom
ataxia 3
vomiting 1
abdominal pain 1
pain 1
starvation 1
Anoxia 1
chills 1
diarrhea 1
hepatosplenomegaly 1
collapse 1
acidity 1
splenomegaly 1
seizures 1
Drug
Glutathione 105
ascorbate 22
vitamin E 11
ROS 10
NADH 4
Bortezomib 3
lysine 3
CSF 2
citric acid 2
ZnCl2 1
Cardiovasc 1
pyridoxal phosphate 1
Tiopronin 1
Alanine 1
Bucillamine 1
Ethanol 1
IL-2 1
Angiotensin II 1
MDS 1
THF 1
CDP 1
TAT 1
Glucantime 1
ABC 1
CoCl2 1
Trypanothione 1
Arsenic trioxide 1
balanced salt solution 1
Xanthium 1
Bestatin 1
Asn 1
Indisulam 1
ZnCl2 1
caffeine 1
Primaquine 1
Leaf 1
Areca 1
NAG 1
CoCl2 1
Enzyme
glutathione synthetase 678
gamma-glutamylcysteine synthetase 147
glutathione reductase 93
catalase 59
superoxide dismutase 55
glutathione peroxidase 55
gamma-glutamyl transpeptidase 40
glutathione S-transferase 30
cysteine synthase 25
5-oxoprolinase 15
caspase-3 12
phytochelatin synthase 11
mitogen-activated protein kinase 11
peroxidase 10
NQO1 10
biotin carboxylase 8
homoglutathione synthetase 8
ATP sulfurylase 8
glucose-6-phosphate dehydrogenase 7
luciferase 7
ascorbate peroxidase 7
heme oxygenase 7
dehydroascorbate reductase 6
D-alanine:D-alanine ligase 6
NADPH oxidase 6
NADPH oxidase 6
alanine aminotransferase 6
MDP 6
ATPase 6
cystathionine beta-synthase 5
pyruvate dehydrogenase 5
pyruvate dehydrogenase 4
glycinamide ribonucleotide transformylase 4
lactate dehydrogenase 4
pyruvate kinase 4
pyruvate dehydrogenase 4
AMP-activated protein kinase 4
thioredoxin reductase 3
methionine adenosyltransferase 3
sulfite reductase 3
SOR 3
SCS 3
succinyl-CoA synthetase 3
cystathionine gamma-lyase 3
dihydrofolate reductase 3
glutamine synthetase 3
peroxiredoxin 3
CD10 3
serine acetyltransferase 3
PDK1 3
sulfite reductase 3
sulfite reductase 3
reverse transcriptase 3
hexokinase 3
acetyl-CoA carboxylase 3
MEK 2
aldehyde dehydrogenase 2
acetate kinase 2
aldehyde dehydrogenase 2
methionine synthase 2
proteasome 2
arginase 2
gamma-glutamylcyclotransferase 2
xanthine oxidase 2
fumarylacetoacetate hydrolase 2
betaine-homocysteine methyltransferase 2
creatine kinase 2
enolase 2
complex I 2
aldolase 2
lipase 2
phospholipid hydroperoxide glutathione peroxidase 2
ERK 2
demethylase 2
methionine synthase 2
protein kinase 2
CPT 2
caspase-9 2
glutaminase 2
ribonucleotide reductase 2
more...
Compound
GSH 316
GSH 316
cysteine 147
oxygen 98
ATP 72
glutamate 59
DNA 52
Dec 41
GSSG 41
cadmium 38
alanine 32
hydrogen 32
phosphate 31
5-oxoproline 30
5-oxoproline 29
5-oxoproline 29
5-oxoproline 29
glucose 24
Clin 23
sodium 21
methionine 20
ECS 20
Gly 19
nitrogen 18
H2O2 18
sulfate 17
3GC 15
gamma-Glutamylcysteine 15
NADPH 14
glutamine 14
ADP 14
water 14
N-acetylcysteine 14
NADPH 14
ADP 13
arginine 13
BSO 13
ADP 13
iron 12
copper 12
NAD 11
glutamic acid 11
NAD 11
nitric oxide 11
His 10
galactose 9
Cysteine 8
salt 8
calcium 8
SDS 8
leucine 8
Mg2+ 8
ethanol 8
proline 7
lysine 7
zinc 7
serine 7
pentose 6
pentose 6
pentose 6
pentose 6
potassium 5
acetate 4
homocysteine 4
salicylic acid 4
ammonium 4
NADH 4
toluene 4
D-Ala 4
selenium 4
DHA 3
Asp 3
Cys-Gly 3
AMP 3
H2S 3
Panam 3
NADP 3
CdCl2 3
Ile 3
LTC4 3
more...