Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.3 (glutathione synthetase)
 678 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
glutathione synthetase 510
GSH 273
GSH synthetase 172
gamma-glutamylcysteine synthetase 115
glutathione reductase 89
ATP 72
catalase 58
Sep 57
glutathione peroxidase 53
Mol 52
superoxide dismutase 51
glutathione S-transferase 26
GSH2 26
glutamate-cysteine ligase 26
Glutathione synthetase 26
GCS 25
gamma-glutamyl transpeptidase 24
GSH1 22
GSR 21
Nrf2 18
reductase 16
5-oxoprolinase 15
SOD 15
caspase-3 14
NADPH 14
erythroid 14
heme oxygenase-1 13
ADP 13
GSS 12
thioredoxin 12
NAD 11
GCL 11
ROS 10
GCLC 10
metallothionein 10
biotin carboxylase 8
gamma-glutamyltranspeptidase 8
DT-diaphorase 8
microsomal 8
p53 8
superoxide dismutase 1 7
insulin 7
peroxidase 7
gamma-glutamyl cyclotransferase 7
glucose-6-phosphate dehydrogenase 7
AP-1 7
Pyruvate carboxylase 6
NQO1 6
glutaredoxin 6
p38 6
PCC 6
glutathione peroxidase 4 6
p65 6
c-Jun 6
GCLM 6
nitric oxide synthase 5
ATPase 5
GTG 5
cytokine 5
MAPK 5
SDS 5
SOD2 5
polypeptide 5
hemoglobin 5
manganese superoxide dismutase 5
apolipoprotein E 4
PC3 4
fused 4
glyoxalase I 4
glutathione peroxidase 1 4
NMR 4
alanine aminotransferase 4
HO-1 4
PC2 4
pyruvate kinase 4
NADH 4
lactate dehydrogenase 4
pyruvate dehydrogenase 4
MnSOD 4
cytochrome P450 3
transcriptional regulator 3
MRP1 3
cytochrome P-450 3
p21 3
GPX2 3
multidrug resistance-associated protein 3
JNK 3
NAC 3
NADP 3
dihydrofolate reductase 3
GGT 3
Kelch-like ECH-associated protein 1 3
Pseudomonas 3
proteasome inhibitor 3
TNF 3
SOD1 3
GCE 3
ICAM-1 3
tumor necrosis factor 3
carp 3
lipopolysaccharide 3
pyruvate dehydrogenase kinase 3
GST 3
thioredoxin reductase 1 3
inducible nitric oxide synthase 3
quinone oxidoreductase 3
esterase 3
AKT 3
Met 3
peroxisome proliferator-activated receptor 3
H2AX 3
MIC 3
hexokinase 3
myeloperoxidase 3
thioredoxin reductase 3
phospholipid hydroperoxide glutathione peroxidase 3
Glutathione peroxidase 3
sulfate transporter 3
dimeric 3
antioxidant enzyme 3
Bot 3
caspase-9 3
acetyl-CoA carboxylase 3
genomic clone 3
glutamine synthetase 3
cytochrome 3
neuronal nitric oxide synthase 3
AMP-activated protein kinase 3
endoplasmic reticulum 3
proteasome 2
LDH 2
P450 2
sulfotransferase 2
cystathionine beta-synthase 2
GCSh 2
nuclear factor (erythroid-derived 2)-like 2 2
GDP 2
xanthine oxidase 2
CBS 2
housekeeping 2
xenobiotic 2
CYP51 2
ATF4 2
fumarylacetoacetate hydrolase 2
cystathionine gamma-lyase 2
casein 2
CBX3 2
tyrosine kinase 2
S-adenosylmethionine synthetase 2
AGS 2
p45 2
phosphoenolpyruvate carboxylase 2
ERK 2
adenosyltransferase 2
ribosomal protein S6 2
aryl hydrocarbon receptor 2
GSTM1 2
FHC 2
NF-E2 2
methionine synthase 2
more...
Disease
GSH 273
cancer 33
hemolytic anemia 26
tumor 22
Alzheimer's disease 12
Krabbe disease 11
5-Oxoprolinuria 8
hepatocellular carcinoma 8
cold 7
HIV 6
pheochromocytoma 6
PCC 6
leukemia 5
cataract 5
SDS 5
diabetes 5
neuroblastoma 4
anemia 4
sepsis 4
malnutrition 4
liver disease 4
carcinoma 4
chlorosis 4
multiple sclerosis 4
sepsis 4
malaria 3
immunodeficiency 3
infectious diseases 3
glioma 3
AIDS 3
amyotrophic lateral sclerosis 3
genetic disorder 3
prostate cancer 3
GCE 3
hyperbilirubinemia 2
metabolic disorder 2
Familial hypercholesterolemia 2
ischemia 2
iron overload 2
homocystinuria 2
lactic acidosis 2
gastric cancer 2
obesity 2
Fanconi 2
macular degeneration 2
rheumatoid arthritis 2
neutropenia 2
carcinogenesis 2
G6PD deficiency 2
folate deficiency 2
AGS 2
CEM 2
Blocking 2
Nonalcoholic fatty liver 2
colon cancer 2
tumor growth 2
colorectal cancer 2
ATM 2
tuberculosis 2
gamma-Glutamyl transpeptidase deficiency 2
primary tumor 2
Mycobacterium 2
Parkinson's disease 2
influenza 2
NAME 2
metabolic syndrome 2
glioblastoma 1
breast cancer 1
cancer recurrence 1
polio 1
Leukemia 1
hypertension 1
Down syndrome 1
dental caries 1
alcohol abuse 1
neoplastic transformation 1
myelosuppression 1
lichen 1
fatty liver 1
schizophrenia 1
duodenal ulcer 1
mental retardation 1
prematurity 1
PAL 1
pulmonary tuberculosis 1
potassium deficiency 1
Klebsiella 1
depression 1
head and neck cancer 1
liver cancer 1
WT1 1
retinitis pigmentosa 1
hypercalciuria 1
virus infection 1
Hepatotoxicity 1
sickle cell disease 1
cystic fibrosis 1
LMS 1
MAS 1
NCR 1
cystinosis 1
MDS 1
osteoarthritis 1
galactosemia 1
cystinuria 1
immunotoxicity 1
renal tubular acidosis 1
atrophic gastritis 1
gastroenteritis 1
mental retardation 1
fits 1
LMS 1
blindness 1
ventricular hypertrophy 1
diabetic retinopathy 1
PCS 1
osteoporosis 1
hyperlipidemia 1
hyperhomocysteinemia 1
AIN 1
PCP 1
periodontitis 1
CLN3 1
pancreatic cancer 1
liver cancer 1
lung cancer 1
macular edema 1
plague 1
peripheral neuropathy 1
Focal segmental glomerulosclerosis 1
varicocele 1
cirrhosis 1
aminoaciduria 1
Tuberculous meningitis 1
bubonic plague 1
cornea 1
enzyme deficiency 1
adenocarcinoma of the lung 1
ductal carcinoma in situ 1
GSD 1
African trypanosomiasis 1
Infection 1
chronic obstructive pulmonary disease 1
non-small cell lung cancer 1
renal cell carcinoma 1
adenocarcinoma 1
hereditary hemochromatosis 1
encephalopathy 1
recurrent cancer 1
drug-induced hepatitis 1
neurological disease 1
Huntington's disease 1
renal impairment 1
squamous cell carcinoma 1
cystoid macular edema 1
LMS 1
uterus 1
Chagas 1
infertility 1
pneumonia 1
more...
Symptom
ataxia 3
vomiting 1
abdominal pain 1
pain 1
starvation 1
Anoxia 1
chills 1
diarrhea 1
hepatosplenomegaly 1
collapse 1
acidity 1
splenomegaly 1
seizures 1
Drug
Glutathione 105
ascorbate 22
vitamin E 11
ROS 10
NADH 4
Bortezomib 3
lysine 3
CSF 2
citric acid 2
ZnCl2 1
Cardiovasc 1
pyridoxal phosphate 1
Tiopronin 1
Alanine 1
Bucillamine 1
Ethanol 1
IL-2 1
Angiotensin II 1
MDS 1
THF 1
CDP 1
TAT 1
Glucantime 1
ABC 1
CoCl2 1
Trypanothione 1
Arsenic trioxide 1
balanced salt solution 1
Xanthium 1
Bestatin 1
Asn 1
Indisulam 1
ZnCl2 1
caffeine 1
Primaquine 1
Leaf 1
Areca 1
NAG 1
CoCl2 1
Enzyme
glutathione synthetase 678
gamma-glutamylcysteine synthetase 147
glutathione reductase 93
catalase 59
glutathione peroxidase 55
superoxide dismutase 55
gamma-glutamyl transpeptidase 40
glutathione S-transferase 30
cysteine synthase 25
5-oxoprolinase 15
caspase-3 12
phytochelatin synthase 11
mitogen-activated protein kinase 11
peroxidase 10
NQO1 10
ATP sulfurylase 8
biotin carboxylase 8
homoglutathione synthetase 8
luciferase 7
heme oxygenase 7
glucose-6-phosphate dehydrogenase 7
ascorbate peroxidase 7
NADPH oxidase 6
ATPase 6
D-alanine:D-alanine ligase 6
MDP 6
dehydroascorbate reductase 6
NADPH oxidase 6
alanine aminotransferase 6
pyruvate dehydrogenase 5
cystathionine beta-synthase 5
pyruvate kinase 4
lactate dehydrogenase 4
pyruvate dehydrogenase 4
pyruvate dehydrogenase 4
AMP-activated protein kinase 4
glycinamide ribonucleotide transformylase 4
peroxiredoxin 3
hexokinase 3
dihydrofolate reductase 3
sulfite reductase 3
thioredoxin reductase 3
reverse transcriptase 3
succinyl-CoA synthetase 3
methionine adenosyltransferase 3
acetyl-CoA carboxylase 3
SOR 3
SCS 3
cystathionine gamma-lyase 3
sulfite reductase 3
glutamine synthetase 3
PDK1 3
sulfite reductase 3
serine acetyltransferase 3
CD10 3
MEK 2
aldehyde dehydrogenase 2
acetate kinase 2
methionine synthase 2
phosphoenolpyruvate carboxykinase 2
arginase 2
collagenase 2
creatine kinase 2
enolase 2
polyphosphate kinase 2
aldolase 2
aldehyde dehydrogenase 2
fumarylacetoacetate hydrolase 2
phospholipid hydroperoxide glutathione peroxidase 2
complex I 2
ERK 2
acyl-CoA dehydrogenase 2
protein kinase 2
proteasome 2
NO synthase 2
betaine-homocysteine methyltransferase 2
aldehyde dehydrogenase 2
phosphoenolpyruvate carboxykinase 2
aldehyde dehydrogenase 2
APS reductase 2
aldehyde dehydrogenase 2
caspase-9 2
glutaminase 2
CPT 2
phosphoenolpyruvate carboxylase 2
phosphoenolpyruvate carboxykinase 2
ribonucleotide reductase 2
lipase 2
gamma-glutamylcyclotransferase 2
methionine synthase 2
nitrogenase 2
xanthine oxidase 2
demethylase 2
riboflavin kinase 2
aryl hydrocarbon hydroxylase 1
P-glycoprotein 1
PAM 1
CPR 1
sorbitol dehydrogenase 1
aspartate aminotransferase 1
diaphorase 1
dihydroxyacetone kinase 1
RNase 1
NADH dehydrogenase 1
nitrate reductase 1
nitrate reductase 1
nitrate reductase 1
nitrite reductase 1
cysteine dioxygenase 1
nitrite reductase 1
ribulose 5-phosphate 3-epimerase 1
nitrite reductase 1
glucose-6-phosphatase 1
inulinase 1
xylulokinase 1
carboxypeptidase Y 1
transketolase 1
nitrate reductase 1
trypanothione reductase 1
phosphodiesterase 1
dimethylarginine dimethylaminohydrolase 1
pyridoxal kinase 1
biliverdin reductase 1
carbamoylphosphate synthetase 1
beta-galactosidase 1
tubulin-tyrosine ligase 1
alcohol dehydrogenase 1
acyl-CoA oxidase 1
succinate dehydrogenase 1
xylitol dehydrogenase 1
urease 1
TAT 1
asparagine synthetase 1
CPS 1
adenylate kinase 1
urokinase-type plasminogen activator 1
focal adhesion kinase 1
pyruvate carboxylase 1
hormone-sensitive lipase 1
CDH 1
trehalose synthase 1
glyoxalase II 1
UDP-N-acetylglucosamine pyrophosphorylase 1
RNase 1
phosphoglycerate kinase 1
acyl-CoA dehydrogenase 1
glutamate dehydrogenase 1
PARP 1
glutamate dehydrogenase 1
thymidylate synthase 1
nitrate reductase 1
aldose reductase 1
AMPK 1
glutamate dehydrogenase 1
betaine aldehyde dehydrogenase 1
malate thiokinase 1
cathepsin K 1
trypsin 1
spermidine synthase 1
PAL 1
more...
Compound
GSH 316
GSH 316
cysteine 147
oxygen 98
ATP 72
glutamate 59
DNA 52
Dec 41
GSSG 41
cadmium 38
alanine 32
hydrogen 32
phosphate 31
5-oxoproline 30
5-oxoproline 29
5-oxoproline 29
5-oxoproline 29
glucose 24
Clin 23
sodium 21
methionine 20
ECS 20
Gly 19
nitrogen 18
H2O2 18
sulfate 17
gamma-Glutamylcysteine 15
3GC 15
NADPH 14
N-acetylcysteine 14
glutamine 14
water 14
ADP 14
NADPH 14
ADP 13
arginine 13
ADP 13
BSO 13
iron 12
copper 12
glutamic acid 11
NAD 11
nitric oxide 11
NAD 11
His 10
galactose 9
leucine 8
Cysteine 8
SDS 8
Mg2+ 8
calcium 8
ethanol 8
salt 8
proline 7
serine 7
zinc 7
lysine 7
pentose 6
pentose 6
pentose 6
pentose 6
potassium 5
D-Ala 4
salicylic acid 4
toluene 4
selenium 4
homocysteine 4
NADH 4
ammonium 4
acetate 4
Asp 3
MIC 3
DHA 3
Cys-Gly 3
ammonia 3
LTC4 3
adenosylmethionine 3
DHA 3
H2S 3
Glutamate 3
Arsenic 3
DHA 3
NADP 3
CdCl2 3
O-acetylserine 3
chromium 3
AMP 3
CO2 3
O-acetylserine 3
Buthionine sulfoximine 3
TNF 3
APAP 3
MTT 3
O-acetylserine 3
Ile 3
Ascorbic acid 3
APS 3
Panam 3
DDP 2
THP 2
Primatol 2
TOF 2
tyrosine 2
propionic acid 2
asparagine 2
propionic acid 2
aspartic acid 2
creatinine 2
Jasmonic acid 2
aldehyde 2
PEG 2
CAT 2
chromate 2
threonine 2
aspartic acid 2
betaine 2
CAT 2
nitrate 2
aflatoxin B1 2
Androgen 2
THP 2
dimethylarsinic acid 2
Ethacrynic acid 2
aspartic acid 2
naphthoquinone 2
silver 2
tert-butyl hydroperoxide 2
naphthoquinone 2
urea 2
1-chloro-2,4-dinitrobenzene 2
naphthoquinone 2
titanium 2
ornithine 2
CBS 2
H2S 2
naphthoquinone 2
naphthoquinone 2
GDP 2
ornithine 2
phosphorus 2
dimethylarsinic acid 2
naphthoquinone 2
CAT 2
adenylate 2
Ethacrynic acid 2
ornithine 2
DEAE 2
dimethylarsinic acid 2
aspartic acid 2
valine 2
dimethylarsinic acid 2
naphthoquinone 2
dimethylarsinic acid 2
beta-alanine 2
acetic acid 2
methane 2
ornithine 2
ABA 2
ornithine 2
aldehyde 2
more...