EC:6.3.2.19 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:6.3.2.19 (ubiquitin-protein ligase)
799 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
ubiquitin-protein ligase	547
ubiquitin	433
proteasome	186
Mol	93
ubiquitin-conjugating enzyme	63
Sep	59
p53	59
Ubiquitin	55
ATP	52
ubiquitin ligase	51
Parkin	43
parkin	36
Nedd4-2	28
endoplasmic reticulum	27
E6-AP	25
SCF	24
ENaC	24
proteasome inhibitor	23
cyclin	22
RSP5	22
E3 ubiquitin ligase	21
UBE3A	20
UBC4	18
E2 ubiquitin-conjugating enzyme	18
E6AP	18
tRNA	16
APC	16
Skp1	13
E6 protein	12
ATPase	12
cytokine	11
UbcH7	11
polypeptide	11
F-box protein	11
alpha-synuclein	11
PINK1	11
HERC1	11
collecting duct	10
interacting protein	10
UBA1	10
RNA polymerase II	10
ubiquitin carrier protein	10
RING-H2	10
NMR	10
Mdm2	9
interferon	9
sodium channel	8
UBE1	8
PARK2	8
ubiquitin-like protein	8
septin	8
novel gene	8
lysozyme	8
histone	8
PTEN	8
cullin	8
proline-rich	8
MDM2	7
histone H2B	7
AMP	7
UBE1L	7
epidermal growth factor receptor	7
membrane protein	7
caspase-3	7
calmodulin	7
UBA6	7
p27	7
NEDD8	6
Met	6
cyclin-dependent kinase	6
securin	6
PARKIN	6
transcriptional activator	6
tumor necrosis factor	6
AAA	6
calpain	6
Proteasome	6
all-trans	6
Cyclin	6
Itch	6

Disease
cancer	82
tumor	55
Parkinson's disease	46
parkinsonism	29
tumorigenesis	21
Angelman syndrome	20
breast cancer	16
APC	16
Liddle's syndrome	14
hypertension	14
lung cancer	12
carcinogenesis	10
carcinoma	9
amyotrophic lateral sclerosis	9
multiple myeloma	9
dementia	8
Alzheimer's disease	8
PARK2	8
lymphoma	7
adenocarcinoma	7
pruritus	7
cervical cancer	7
AAA	6
abdominal aortic aneurysm	6
mental retardation	5
muscular atrophy	5
tumor progression	5
Huntington's disease	5
mental retardation	5
MCF	5
non-small cell lung cancer	5
acute promyelocytic leukemia	5
autism	5
colorectal cancer	5
neuroblastoma	4
lung carcinoma	4
SDS	4
Hippel	4
squamous cell carcinoma	4
prostate cancer	4
metastases	4
hepatocellular carcinoma	4
virus infection	4
leukemia	4
developmental delay	3
sepsis	3
heart failure	3
retinoblastoma	3
Blocking	3
respiratory failure	3
ARF	3
melanoma	3
tumor growth	3
IBR	3
papilloma	3
immunodeficiency	3
sepsis	3
pancreatic cancer	3
Still	2
aggressiveness	2
cognitive impairment	2
Japanese encephalitis	2
depression	2
Epstein	2
cirrhosis	2
dysplasia	2
synovial sarcoma	2
Heller	2
cystic fibrosis	2
obesity	2
metastatic melanoma	2
PML	2
obsessive-compulsive disorder	2
Kaposi's sarcoma	2
GSH	2
cardiovascular disease	2
mantle cell lymphoma	2
glioma	2
oral cancer	2
skin cancer	2

Enzyme
ubiquitin-protein ligase	799
proteasome	188
protein kinase	26
APC	18
ERK	14
RNA polymerase	13
ATPase	12
mitogen-activated protein kinase	10
lysozyme	8
luciferase	7
glutathione S-transferase	7
caspase-3	7
isopeptidase	6
cdc2	5
IKK	5
protein kinase C	4
3C protease	4
calcineurin	4
RNase	4
complex I	4
PARP	3
trypsin	3
superoxide dismutase	3
focal adhesion kinase	3
transcriptase	3
ubiquityl-calmodulin synthetase	3
m-calpain	2
ornithine decarboxylase	2
phosphoinositide 3-kinase	2
leucine aminopeptidase	2
hexokinase	2
enolase	2
beta-galactosidase	2
protein phosphatase 2A	2
DNA ligase	2
trehalase	2
DNA ligase	2
reverse transcriptase	2
diaphorase	2
aminopeptidase I	2
topoisomerase	2
NADH dehydrogenase	2
ribonuclease	2
diacylglycerol kinase	2
RNase	2
arginyl-tRNA synthetase	2
phospholipase C	2
granzyme B	2
ribonuclease	2
carbonic anhydrase	1
AMP-activated protein kinase	1
transketolase	1
ACS	1
DNase	1
glucose-6-phosphate dehydrogenase	1
IscS	1
cystathionine beta-synthase	1
renin	1
heme oxygenase	1
E-2	1
cytochrome oxidase	1
chaperonin	1
chorismate mutase	1
cathepsin D	1
DNA polymerase	1
isocitrate dehydrogenase	1
beta-glucosidase	1
lipase	1
ECH	1
chymotrypsin	1
NQO1	1
proteinase K	1
ATP synthase	1
furin	1
isocitrate dehydrogenase	1
type 1 protein phosphatase	1
acid phosphatase	1
3-hydroxy-3-methylglutaryl-CoA reductase	1
cysteine synthase	1
TOR	1