Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.19 (ubiquitin-protein ligase)
 799 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ubiquitin-protein ligase 547
ubiquitin 433
proteasome 186
Mol 93
ubiquitin-conjugating enzyme 63
Sep 59
p53 59
Ubiquitin 55
ATP 52
ubiquitin ligase 51
Parkin 43
parkin 36
Nedd4-2 28
endoplasmic reticulum 27
E6-AP 25
ENaC 24
SCF 24
proteasome inhibitor 23
RSP5 22
cyclin 22
more...
Disease
cancer 82
tumor 55
Parkinson's disease 46
parkinsonism 29
tumorigenesis 21
Angelman syndrome 20
APC 16
breast cancer 16
Liddle's syndrome 14
hypertension 14
lung cancer 12
carcinogenesis 10
multiple myeloma 9
carcinoma 9
amyotrophic lateral sclerosis 9
Alzheimer's disease 8
PARK2 8
dementia 8
pruritus 7
cervical cancer 7
more...
Symptom
seizures 9
starvation 7
ataxia 5
collapse 2
weakness 2
tremor 2
overweight 1
cerebellar ataxia 1
functional recovery 1
dystonia 1
ataxic gait 1
acidity 1
hypotonia 1
Drug
Parkin 43
Parkin 43
lysine 34
Bortezomib 4
TAK 2
GEO 2
uPA 1
Dermatol 1
Alanine 1
Dasatinib 1
NADH 1
CPT-11 1
Arsenic trioxide 1
caffeine 1
CIA 1
Taxol 1
Ginseng 1
AMC 1
Pirarubicin 1
nitroglycerin 1
more...
Enzyme
ubiquitin-protein ligase 799
proteasome 188
protein kinase 26
APC 18
ERK 14
RNA polymerase 13
ATPase 12
mitogen-activated protein kinase 10
lysozyme 8
glutathione S-transferase 7
caspase-3 7
luciferase 7
isopeptidase 6
cdc2 5
IKK 5
calcineurin 4
3C protease 4
complex I 4
RNase 4
protein kinase C 4
more...
Compound
DNA 71
Dec 54
lysine 53
ATP 52
Ubiquitin 43
sodium 26
cysteine 26
arginine 18
Cbl 18
tyrosine 17
zinc 16
salt 16
serine 14
aldosterone 14
calcium 12
leucine 12
methionine 11
threonine 10
alanine 10
glucose 9
more...