Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:6.3.2.19 (ubiquitin-protein ligase)
799 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein ubiquitin-protein ligase 0.683 RSP5 0.008 ubiquitin-conjugating enzyme 0.008 ubiquitin 0.007 Ubiquitin-protein ligase 0.006 E6-AP 0.004 UBC4 0.004 Nedd4-2 0.004 E2-F1 0.003 ubiquitin carrier protein 0.003 UBA6 0.003 HERC1 0.002 Praja-1 0.002 UFD2 0.002 UBA1 0.002 E2 ubiquitin-conjugating enzyme 0.002 UbcH7 0.002 proteasome 0.002 ANKRD13A 0.002 KIAA0675 0.002 Ubiquitin-like modifier activating enzyme 1 0.002 ANKRD13D 0.002 ANKRD13B 0.002 FBL7 0.002 hect domain and RLD 5 0.002 NEDD4 protein 0.002 E6AP 0.002 UBE1 0.002 UBE3A 0.001 parkin 0.001 Parkin 0.001 KIAA0554 0.001 40S ribosomal protein S3a 0.001 C1QL4 0.001 arrestin domain containing 4 0.001 5'-3' exoribonuclease 2 0.001 UBE1L 0.001 CDC26 0.001 Cellular tumor antigen p53 0.001 DRIP1 0.001 RFPL4 0.001 DnaJ/Hsp40 chaperone 0.001 ubiquitin-like modifier activating enzyme 3 0.001 SMAX2 0.001 Ubiquitin 0.001 FBXO6 0.001 RING-H2 0.001 FBXO17 0.001 PMEPA1 protein 0.001 Ring finger protein 1 0.001 sideroflexin 2 0.001 DRIP2 0.001 coactivator for steroid receptors 0.001 HIRIP3 0.001 ZNF645 0.001 RNF186 0.001 arginyl-tRNA-protein transferase 0.001 APC11 0.001 WBP-1 0.001 chromodomain helicase DNA binding protein 2 0.001 EIF-5A 0.001 RNF128 0.001 KDELR3 0.001 FKBP3 0.001 Vaccinia-related kinase 3 0.001 TOP1 protein 0.001 UbcH8 0.001 ubiquitin ligase 0.001 RNF206 0.001 FBG3 0.001 ADP-ribosylation factor domain protein 1 0.001 UBP43 0.001 USE1 0.001 CCNF 0.001 HACE1 0.001 Ubiquitin-activating enzyme 0.001 FBXO27 0.001 SWM1 0.001 ubiquitin thiolesterase 0.001 seven in absentia homolog 2 0.001 ARIH1 0.001 CGR19 0.000 heterogeneous nuclear ribonucleoprotein A3 0.000 RNF26 0.000 WWP2 0.000 AHNAK protein 0.000 CPSF7 0.000 Multidrug resistance protein 3 0.000 SPINK2 0.000 VPS13D 0.000 PAIP1 0.000 nucleolar and coiled-body phosphoprotein 1 0.000 TOMM22 0.000 TINO 0.000 ARRDC4 0.000 PHP2 0.000 RuvB-like 2 0.000 EF1B 0.000 CDC16 0.000 UBR1 0.000 NTKL 0.000 insulin induced gene 1 0.000 RNF139 0.000 rpl11 0.000 WW domain binding protein 2 0.000 DZIP3 0.000 FBG1 0.000 FAT10 0.000 cyclin F 0.000 E6 protein 0.000 ENaC 0.000 cbl-b 0.000 HELZ 0.000 RAI3 0.000 SALL4B 0.000 Doc1 0.000 Uba5 0.000 TRIP12 0.000 FBL3 0.000 TRIM36 0.000 ubiquitin-fold modifier 1 0.000 MDP1 0.000 MAGE-D 0.000 MEX67 0.000 TPRD 0.000 RING-IBR 0.000 MYCBP2 0.000 RNF41 0.000 CDC23 0.000 RTF1 0.000 E6TP1 0.000 Layilin 0.000 GRIP2 0.000 cdc2-related protein kinase 0.000 APC8 0.000 Skp1 0.000 AGP1 0.000 AIP2 0.000 UBE2D1 0.000 UBA3 0.000 ubiquitin-activating enzyme E1 0.000 UBE2G2 0.000 PCTK1 0.000 HBZ protein 0.000 FAP48 0.000 PIRH2 0.000 Ubc6p 0.000 UbcH6 0.000 synphilin-1 0.000 RNF40 0.000 Ufc1 0.000 LDOC1 0.000 HSJ1a 0.000 SLC25A5 0.000 RING finger protein 0.000 TMX1 0.000 STAM-1 0.000 ARAF1 0.000 MTMR4 0.000 PDZRN3 0.000 UFM1 0.000 Pop1 0.000 NOT4 0.000 RNF144A 0.000 Ubiquitin carboxyl-terminal hydrolase 0.000 APC10 0.000 transformation/transcription domain-associated protein 0.000 UBE3A protein 0.000 UBE2G1 0.000 PSMD1 0.000 TRAIP 0.000 SCF 0.000 sigma 3 protein 0.000 YAP65 0.000 UBE2O 0.000 formin-like 1 0.000 FBXW8 0.000 PARK2 0.000 PDS5 0.000 UBE2M 0.000 PICT-1 0.000 SALL3 0.000 UBA2 0.000 MMS2 0.000 PARKIN 0.000 GORAB 0.000 VCY2 0.000 MTHFS 0.000 TRAF-interacting protein 0.000 UBE2L3 0.000 AKAP3 0.000 APP-BP1 0.000 NEDD4 0.000 Ubiquitin-conjugating enzyme 0.000 HUWE1 0.000 UHRF2 0.000 PSMD7 0.000 E3 protein 0.000 PSMD14 0.000 UBE2H 0.000 RNF216 0.000 UBC9 0.000 SHFM3 0.000 NEDD4-2 0.000 SFT 0.000 ubiquitin-protein isopeptide ligase (E3) 0.000 AE4 0.000 proteasome inhibitor 0.000 sentrin-specific protease 0.000 NPH3 0.000 PSMC4 0.000 F-box protein 0.000 putative E3 ubiquitin ligase 0.000 RIG1 0.000 BRUCE 0.000 TOPORS 0.000 TOM70 0.000 PINK1 0.000 UBR5 0.000 ubiquitin-like protein 0.000 NLRP2 0.000 HNRNPK 0.000 PSMA1 0.000 amino acid permease 0.000 NEDD4L 0.000 UBC7 0.000 kinase-like protein 0.000 ubiquitin-protein isopeptide ligase 0.000 EEF2 0.000 UBC2 0.000 HOIL-1 0.000 RPS4X 0.000 securin 0.000 finger protein 0.000 cAMP responsive element modulator 0.000 GSPT1 0.000 diubiquitin 0.000 myeloid zinc finger 1 0.000 NYGGF4 0.000 SRP14 0.000 NEDD8 0.000 SKP2 0.000 ubiquitin-like protein Nedd8 0.000 UBR4 0.000 ubiquitin-conjugating enzyme E2 0.000 TNF receptor-associated factor 3 0.000 CSE1 0.000 septin 0.000 elongin C 0.000 RBBP8 0.000 cullin 0.000 Ankyrin 0.000 RPN2 0.000 brca2 0.000 HMGCS1 0.000 FLRF 0.000 anaphase-promoting complex/cyclosome 0.000 E3 ubiquitin ligase 0.000 GPX7 0.000 PMEPA1 0.000 LNX 0.000 APC1 0.000 RING1 0.000 RNF11 0.000 Derlin-2 0.000 UQCRC1 0.000 NDUFS2 0.000 CDC20 0.000 Mule 0.000 USP22 0.000 Itch 0.000 USP18 0.000 p53-binding protein 0.000 RING1A 0.000 POSH 0.000 GREM2 0.000 HSD17B10 0.000 BI-1 0.000 CCR4-NOT 0.000 Voltage-gated sodium channel 0.000 NEDD4-1 0.000 SPT6 0.000 NPI-1 0.000 Sharpin 0.000 arginyl-tRNA synthetase 0.000 RCC1-like 0.000 DIAP1 0.000 ring finger protein 0.000 RBX1 0.000 RP-A 0.000 SRP9 0.000 Ubc13 0.000 ribosomal protein L11 0.000 SAE1 0.000 PTPRJ 0.000 histone H2B 0.000 scribble 0.000 Mdm2 0.000 sperm surface protein 0.000 Pellino 0.000 PTPRG 0.000 SUG1 0.000 TOP2B 0.000 TRIM21 0.000 +Ca 0.000 acrosin inhibitor 0.000 NCK1 0.000 INSIG1 0.000 ARD1 0.000 SAE2 0.000 CDC27 0.000 RNF43 0.000 IMPDH2 0.000 Cullin-1 0.000 TOM1 0.000 par-4 0.000 DNAJB6 0.000 Grp170 0.000 LRPPRC 0.000 eps15 0.000 TCR zeta chain 0.000 gp78 0.000 ubiquitin C 0.000 Sec62 0.000 ClC-5 0.000 MGD1 0.000 TPI1 0.000 cell cycle-related protein 0.000 CRV 0.000 HLA-F 0.000 1C5 0.000 XRN2 0.000 CHD2 0.000 cullin 3 0.000 ubiquitin fusion protein 0.000 sentrin 0.000 BMP10 0.000 ubiquitin conjugating enzyme 0.000 ORP150 0.000 EF1A 0.000 RBP1 0.000 USP10 0.000 RNF168 0.000 cyclin 0.000 UBB 0.000 Cdc48 0.000 POMP 0.000 PPP2R1A 0.000 PSP94 0.000 atrogin-1 0.000 EPHB2 0.000 Hdm2 0.000 Hsp70-interacting protein 0.000 p53 0.000 Skp2 0.000 SKP1 0.000 ARI 0.000 TRIM32 0.000 hepatocyte growth factor-regulated tyrosine kinase substrate 0.000 efp 0.000 protein phosphatase 2 0.000 ubiquitin-specific protease 0.000 RNF20 0.000 TRIM24 0.000 PRDX6 0.000 WW domain-containing 0.000 GRAIL 0.000 LBP-1 0.000 barttin 0.000 UT-A2 0.000 CUL4B 0.000 RNF213 0.000 CUL1 0.000 USP8 0.000 Mex67 0.000 Rbx1 0.000 p53 binding protein 0.000 SHARPIN 0.000 VACM-1 0.000 p32) 0.000 Derlin-1 0.000 gene 4 0.000 UBC 0.000 JAB1 0.000 EDD 0.000 ubiquitin-conjugating enzyme 9 0.000 CRBN 0.000 RanBP2 0.000 eIF-3 0.000 UBE2C 0.000 Rpn13 0.000 HSPD1 0.000 UCH-L1 0.000 ECT2 0.000 APC 0.000 CHFR 0.000 AHNAK 0.000 CLCN5 0.000 SALL1 0.000 CIN85 0.000 MAP1LC3B 0.000 zinc metallopeptidase 0.000 Proteasome 0.000 iron regulatory protein 2 0.000 calcium-independent phospholipase A2 0.000 alpha-synuclein 0.000 RBCC 0.000 WD-repeat protein 0.000 ERN1 0.000 RING-finger protein 0.000 CBL 0.000 NURR1 0.000 hnRNP D 0.000 Gab2 0.000 HOXA1 0.000 spliceosomal protein 0.000 COP9 0.000 DGK 0.000 CCND3 0.000 TRRAP 0.000 KEN 0.000 YWHAE 0.000 SUMO2 0.000 Elongin B 0.000 HRD1 0.000 deubiquitinating enzyme 0.000 p27Kip1 0.000 granulocyte colony-stimulating factor receptor 0.000 HERC2 0.000 PSAP 0.000 ubiquitin protease 0.000 UBC13 0.000 CUL3 0.000 Fe65 0.000 calcium-activated neutral protease 0.000 lysosome-associated membrane protein-2 0.000 ATXN2 0.000 PHR1 0.000 HDM2 0.000 TSG101 0.000 FANCJ 0.000 ubiquitin carboxyl-terminal hydrolase 0.000 S-adenosyl-L-homocysteine hydrolase 0.000 HBZ 0.000 thioredoxin interacting protein 0.000 AIF4 0.000 RNF4 0.000 sugar transporter 0.000 tropomodulin 0.000 AP180 0.000 ACAT2 0.000 GABRB3 0.000 FAT1 0.000 ZFX 0.000 collecting duct 0.000 E1B 0.000 HSF2 0.000 CARD9 0.000 helicase II 0.000 BMF 0.000 NACP 0.000 ribosomal protein S6 kinase 1 0.000 CUL4 0.000 KIP1 0.000 glycine-rich protein 0.000 BMP9 0.000 FBA 0.000 Rpn10 0.000 NAIP 0.000 PARK6 0.000 RAD1 0.000 ISG15 0.000 MFF 0.000 SRP54 0.000 histone H2A 0.000 TIP60 0.000 TEK 0.000 FBXW7 0.000 RECK 0.000 ATP 0.000 gamma-tubulin 0.000 MTA1 0.000 CASK 0.000 VHL protein 0.000 TRIP 0.000 carboxylating 0.000 Cyclin 0.000 synexin 0.000 PWI 0.000 UCHL1 0.000 HDEL 0.000 KAI1 0.000 ELK1 0.000 P29 0.000 HAND1 0.000 heterogeneous nuclear ribonucleoprotein K 0.000 Cap43 0.000 ficolin 0.000 TRIM 0.000 BRIP1 0.000 RLR 0.000 geminin 0.000 SC35 0.000 CHIP 0.000 protein phosphatase 2C 0.000 CYLD 0.000 TRIM25 0.000 ubiquitin C-terminal hydrolase 0.000 SGK1 0.000 CKB 0.000 MTH1 0.000 retinal protein 0.000 LIG4 0.000 dishevelled 0.000 HIF-1beta 0.000 GW182 0.000 dentatorubral-pallidoluysian atrophy 0.000 MAD2 0.000 ataxin-1 0.000 interacting protein 0.000 AAA 0.000 YWHAZ 0.000 pericentrin 0.000 IkappaB kinase 0.000 Id4 0.000 cereblon 0.000 RNF8 0.000 TXNIP 0.000 synaptojanin 0.000 pVHL 0.000 thymopoietin 0.000 lactotransferrin 0.000 ephrin-B1 0.000 HNA 0.000 MDM2 0.000 MuRF 0.000 proline-rich 0.000 CRABP 0.000 p45 0.000 cIAP2 0.000 coilin 0.000 p97 0.000 Nav1.5 0.000 novel gene 0.000 kelch 0.000 cysteine desulfurase 0.000 TOP1 0.000 IL23R 0.000 spinocerebellar ataxia type 2 0.000 R12 0.000 DRP1 0.000 Mol 0.000 GAT1 0.000 optineurin 0.000 Phosphatase and tensin homolog 0.000 FKBP51 0.000 p105 0.000 NADH-ubiquinone oxidoreductase 0.000 aryl hydrocarbon receptor nuclear translocator 0.000 peptidoglycan recognition protein 0.000 AF-1 0.000 mitofusin 2 0.000 MAPK3 0.000 SLUG 0.000 REDD1 0.000 ATG7 0.000 promyelocytic leukemia protein 0.000 PDE2 0.000 aldolase B 0.000 potential tumor suppressor 0.000 MDC1 0.000 melanocortin 1 receptor 0.000 caspase 6 0.000 CtIP 0.000 MICB 0.000 seminal plasma protein 0.000 ATG16L1 0.000 XPB 0.000 endoplasmic reticulum 0.000 Atrogin-1 0.000 partial protein 0.000 Sp1 protein 0.000 beta-spectrin 0.000 RasGAP 0.000 CCL7 0.000 DAN 0.000 XIAP 0.000 dynamin-related protein 1 0.000 RNA polymerase II 0.000 antizyme 0.000 sodium channel 0.000 NFE2L2 0.000 AICAR 0.000 H2A 0.000 extracellular signal regulated kinase 0.000 A-kinase anchoring protein 0.000 CRL4 0.000 Dnmt3b 0.000 X-linked inhibitor of apoptosis protein 0.000 Id3 0.000 tRNA 0.000 coiled-coil protein 0.000 activating transcription factor 6 0.000 Pin1 0.000 LMO2 0.000 Zap 0.000 cyclin-dependent kinase inhibitor p27 0.000 SLI 0.000 GAP43 0.000 serine/threonine-protein kinase 0.000 endoprotease 0.000 farnesyl diphosphate synthase 0.000 pendrin 0.000 PKC zeta 0.000 truncated variant 0.000 Ro52 0.000 FKBP52 0.000 separase 0.000 BIRC5 0.000 14-3-3 0.000 trehalase 0.000 PGK1 0.000 p27(KIP1) 0.000 MOT 0.000 histone deacetylase 6 0.000 VCP 0.000 Hsp40 0.000 SMAD3 0.000 transgelin 0.000 Set1 0.000 inhibitor of apoptosis 0.000 PABP 0.000 LRRK2 0.000 KCa3.1 0.000 tumor suppressor protein 0.000 CIA 0.000 anion transporter 0.000 DDB1 0.000 HMG-CoA synthase 0.000 IRAK1 0.000 RP11 0.000 IkappaBalpha 0.000 PTEN 0.000 NOTCH3 0.000 activating transcription factor 3 0.000 H2B 0.000 AQP2 0.000 EF-Tu 0.000 MuRF1 0.000 p73 0.000 cyclin-dependent kinase 0.000 SUMO1 0.000 LAP 0.000 DBT 0.000 Toll/interleukin-1 receptor 0.000 E2 protein 0.000 TRF1 0.000 promyelocytic leukemia 0.000 calpain 0.000 p27 0.000 US2 0.000 p20 0.000 regucalcin 0.000 aldolase A 0.000 Tom40 0.000 cIAP1 0.000 TAK 0.000 BP1 0.000 PHP 0.000 p32 0.000 TFE3 0.000 zinc finger motif 0.000 transcriptional activator 0.000 O6-methylguanine-DNA methyltransferase 0.000 NPR1 0.000 processed form 0.000 MAPK1 0.000 PRC1 0.000 expressed in testis 0.000 Glycogen synthase 0.000 p80 0.000 Hexokinase 0.000 DNMT3A 0.000 lysosomal protein 0.000 p62 0.000 nuclear factor of activated T-cells 0.000 Dnmt3a 0.000 FHIT 0.000 cyclin-dependent kinase inhibitor 0.000 DJ-1 0.000 squalene synthase 0.000 RAD50 0.000 OPA1 0.000 CCAAT/enhancer-binding protein homologous protein 0.000 granzyme A 0.000 Brca1 0.000 Occludin 0.000 COL3A1 0.000 polo-like kinase 1 0.000 CIP1/WAF1 0.000 transcription repressor 0.000 ARNT 0.000 VHL 0.000 serine/threonine kinase 0.000 zinc transporter 0.000 53BP1 0.000 Mad2 0.000 ataxin-3 0.000 NEP 0.000 CIC 0.000 L11 0.000 LC3B 0.000 78 kDa 0.000 N-myc 0.000 leucine-rich repeat kinase 2 0.000 MRE11 0.000 TOP2A 0.000 mdm2 0.000 glycerol kinase 0.000 alpha-ketoglutarate dehydrogenase 0.000 SMAD4 0.000 ARF 0.000 nuclear hormone receptor 0.000 HDAC4 0.000 single-stranded DNA-binding protein 0.000 Id1 0.000 PAK1 0.000 RAD52 0.000 RIP1 0.000 SUMO-1 0.000 poly(A)-binding protein 0.000 p90 0.000 ASK1 0.000 HIS3 0.000 organic anion transporter 0.000 p14 0.000 HSF1 0.000 cyclin B1 0.000 eukaryotic translation initiation factor 0.000 caveolin-3 0.000 guanine nucleotide binding protein 0.000 ICAM-3 0.000 alpha, beta 0.000 MDA5 0.000 TRAF6 0.000 4EBP1 0.000 RP4 0.000 NBS1 0.000 all-trans 0.000 small GTPase 0.000 DICER1 0.000 linker histone 0.000 HA2 0.000 ALA 0.000 GDF15 0.000 TFIIH 0.000 diacylglycerol kinase 0.000 Notch3 0.000 APH 0.000 adapter protein 0.000 mitochondrial ATPase 0.000 p34 0.000 GEF 0.000 chimeric protein 0.000 Transporter 0.000 serine/threonine protein kinase 0.000 nucleolar protein 0.000 AP-2 0.000 cytochrome P450 2E1 0.000 PEST 0.000 TDP-43 0.000 MSV 0.000 prolyl isomerase 0.000 PDB 0.000 Huntingtin 0.000 heat shock protein 90 0.000 elongation factor 2 0.000 syntaxin 0.000 Dnmt1 0.000 MAD 0.000 dynactin 0.000 chloride channel 0.000 SHP 0.000 ADP-ribosylation factor 0.000 Yes 0.000 nuclear protein 0.000 L12 0.000 Kir2.1 0.000 Cyclin-dependent kinase 0.000 adenomatous polyposis coli 0.000 cyclin D3 0.000 zinc finger 0.000 ribosomal S6 kinase 0.000 DNA repair protein 0.000 B protein 0.000 fetal kidney 0.000 protein-tyrosine phosphatase 0.000 GAL1 0.000 LAT 0.000 NADH dehydrogenase 0.000 TM3 0.000 protein-tyrosine kinase 0.000 RNase A 0.000 BiP 0.000 metallopeptidase 0.000 FKBP12 0.000 metastasis suppressor 0.000 interferon regulatory factor 3 0.000 like kinase 0.000 CK2 0.000 SRC-1 0.000 GTPase-activating protein 0.000 PKS 0.000 E2F-1 0.000 ATF6 0.000 GAL 0.000 TM1 0.000 H2AX 0.000 unknown function 0.000 DIABLO 0.000 adipose triglyceride lipase 0.000 retinoic acid receptor alpha 0.000 homeodomain transcription factor 0.000 TRIF 0.000 Axin 0.000 Creatine kinase 0.000 PML 0.000 KCNQ1 0.000 adaptor protein 0.000 SUMO 0.000 DNA repair enzyme 0.000 c-fms 0.000 lysozyme 0.000 S10 0.000 C protein 0.000 Smac 0.000 HSP60 0.000 ataxia telangiectasia mutated 0.000 Apaf-1 0.000 HA1 0.000 N-glycanase 0.000 endoglin 0.000 protein phosphatase 0.000 cdk2 0.000 MPN 0.000 HSD1 0.000 PGP 9.5 0.000 signal recognition particle 0.000 Rab7 0.000 p11 0.000 EST) 0.000 histone H3 0.000 MYB 0.000 MCP-3 0.000 calpastatin 0.000 tensin 0.000 voltage-gated sodium channel 0.000 Cu/Zn superoxide dismutase 0.000 pRb 0.000 S100A8 0.000 NHE1 0.000 FGF8 0.000 vascular endothelial growth factor receptor 2 0.000 MMR 0.000 casein kinase 0.000 transketolase 0.000 ankyrin 0.000 DNMT3B 0.000 spleen tyrosine kinase 0.000 CDK6 0.000 quinone oxidoreductase 0.000 MyoD 0.000 TOR 0.000 SCD1 0.000 Chk2 0.000 Met 0.000 ATPase 0.000 IAP 0.000 CDH1 0.000 p17 0.000 DSS 0.000 agouti 0.000 CIS 0.000 epidermal growth factor receptor 0.000 tumour suppressor 0.000 C2H2 0.000 dynamin 0.000 GST 0.000 mineralocorticoid receptor 0.000 VIM 0.000 calmodulin 0.000 DEAD 0.000 testis-specific 0.000 Smad1 0.000 cyclin dependent kinase 0.000 enolase 0.000 pyrophosphatase 0.000 GTPase 0.000 DNA ligase 0.000 PARP1 0.000 cyclin A 0.000 C/EBP homologous protein 0.000 SRC 0.000 protein disulfide isomerase 0.000 LC3 0.000 p12 0.000 hepatocyte growth factor 0.000 granzyme B 0.000 TLR9 0.000 ERBB2 0.000 interferon-beta 0.000 c-MYC 0.000 Epidermal growth factor receptor 0.000 muscle protein 0.000 factor H 0.000 FBS 0.000 Aurora-A 0.000 Hsp60 0.000 hormone receptor 0.000 histone methyltransferase 0.000 CMS 0.000 MIM 0.000 pepsinogen 0.000 troponin T 0.000 BMP2 0.000 Histone deacetylase 0.000 titin 0.000 INS-1 0.000 PERK 0.000 splicing factor 0.000 DNA polymerase alpha 0.000 glutaminase 0.000 SOD1 0.000 membrane protein 0.000 zinc finger protein 0.000 P19 0.000 FGFR1 0.000 thyroid hormone receptor 0.000 DNA binding protein 0.000 leucine zipper 0.000 ATF 0.000 transcriptional regulator 0.000 inward rectifier 0.000 AAG 0.000 platelet-derived growth factor receptor 0.000 HSP70 0.000 poly (ADP-ribose) polymerase 0.000 cathepsin L 0.000 motor protein 0.000 HEK 0.000 TNM 0.000 polypeptide 0.000 HIF-1alpha 0.000 MDP 0.000 p55 0.000 p50 0.000 proto-oncogene 0.000 glucocerebrosidase 0.000 alpha-tubulin 0.000 cyclin D1 0.000 PKR 0.000 cyclin E 0.000 proliferating cell nuclear antigen 0.000 autoantigen 0.000 outer mitochondrial membrane 0.000 GTP-binding protein 0.000 SP1 0.000 matrix protein 0.000 EZH2 0.000 myostatin 0.000 PP1 0.000 ribonuclease A 0.000 chaperonin 0.000 alpha-actinin 0.000 histone 0.000 phosphatase and tensin homolog 0.000 hedgehog 0.000 methylguanine-DNA methyltransferase 0.000 MyD88 0.000 manganese superoxide dismutase 0.000 Sep 0.000 NQO1 0.000 HDAC1 0.000 Epidermal growth factor 0.000 nuclear receptor 0.000 Bid 0.000 hexokinase 0.000 MYC 0.000 RIG-I 0.000 CLL 0.000 p15 0.000 receptor tyrosine kinase 0.000 prion 0.000 dystrophin 0.000 core protein 0.000 major histocompatibility complex class I 0.000 thioredoxin reductase 0.000 JAK2 0.000 c-Met 0.000 MIB 0.000 GABA(A) receptor 0.000 E2F1 0.000 tumor necrosis factor receptor 0.000 synuclein 0.000 calreticulin 0.000 interferon 0.000 IKK 0.000 Rho 0.000 cathepsin 0.000 AMP 0.000 CPR 0.000 retinoic acid receptor 0.000 histone acetyltransferase 0.000 PARP-1 0.000 HGF 0.000 DAG 0.000 enigma 0.000 cadherin 0.000 cytokine receptor 0.000 phosphoinositide 3-kinase 0.000 DNMT1 0.000 interleukin-6 0.000 progesterone receptor 0.000 TLR7 0.000 MLR 0.000 cytoplasmic protein 0.000 MnSOD 0.000 DPP 0.000 Janus kinase 0.000 protein C 0.000 histone H1 0.000 ornithine decarboxylase 0.000 bFGF 0.000 CD105 0.000 galectin-3 0.000 c-Jun 0.000 caspase-3 0.000 CaMKII 0.000 DNA-dependent protein kinase 0.000 INK4a 0.000 D. melanogaster 0.000 hsp70 0.000 Chk1 0.000 isocitrate dehydrogenase 0.000 C-terminal peptide 0.000 pol 0.000 vimentin 0.000 VP2 0.000 estrogen receptor 0.000 arrestin 0.000 P21 0.000 sky 0.000 phosphatase 0.000 flavoprotein 0.000 transmembrane protein 0.000 NAD 0.000 p63 0.000 TRAIL 0.000 Fas 0.000 glutathione S-transferase 0.000 cage 0.000 mutant p53 0.000 ALS 0.000 STAT5 0.000 H-ras 0.000 sonic hedgehog 0.000 DNA gyrase 0.000 A-T 0.000 vascular endothelial growth factor A 0.000 ERK2 0.000 p65 0.000 K12 0.000 vinculin 0.000 RACE 0.000 occludin 0.000 galanin 0.000 ryanodine receptor 0.000 transcriptional factor 0.000 G protein-coupled receptor 0.000 X-chromosome 0.000 aminopeptidase 0.000 type I interferon 0.000 erythropoietin 0.000 MMP 0.000 topoisomerase I 0.000 serotonin transporter 0.000 beta-catenin 0.000 cytochrome c 0.000 PGC 0.000 cystic fibrosis transmembrane conductance regulator 0.000 spermatozoa 0.000 STAT 0.000 CDK4 0.000 MAS 0.000 neu 0.000 peroxisome proliferator-activated receptor 0.000 threonine 0.000 cytokine 0.000 tyrosine kinase 0.000 TLR4 0.000 peptidase 0.000 KIT 0.000 FK506 0.000 heat shock protein 0.000 vitronectin 0.000 telomeric 0.000 short form 0.000 caspase-9 0.000 ERK 0.000 MET 0.000 Fas ligand 0.000 PC3 0.000 DNA methyltransferase 0.000 crystallin 0.000 MHC class I 0.000 cysteine protease 0.000 cathepsin D 0.000 c-myc 0.000 ribosomal protein 0.000 membrane-bound 0.000 poly(ADP-ribose) polymerase 0.000 catenin 0.000 p38 0.000 PARP 0.000 tumor necrosis factor 0.000 RNA-binding protein 0.000 ABO 0.000 tropomyosin 0.000 survivin 0.000 MMP-9 0.000 envelope glycoprotein 0.000 NMR 0.000 aryl hydrocarbon receptor 0.000 methyltransferase 0.000 cell adhesion molecule 0.000 trypsin inhibitor 0.000 tau protein 0.000 SOD 0.000 Ki-67 0.000 p21 0.000 PC-3 0.000 erythroid 0.000 HMG-CoA reductase 0.000 CCL2 0.000 ART 0.000 ubiquinone 0.000 p38 mitogen-activated protein kinase 0.000 STAT3 0.000 apolipoprotein B 0.000 fur 0.000 vasopressin 0.000 phosphorylating 0.000 neurotrophin 0.000 dimeric 0.000 androgen receptor 0.000 cAMP-dependent protein kinase 0.000 ferredoxin 0.000 interleukin-4 0.000 cytochrome P450 0.000 glucose-6-phosphate dehydrogenase 0.000 plasminogen activator inhibitor-1 0.000 EGF receptor 0.000 IVF 0.000 serum protein 0.000 Dictyostelium 0.000 mast cell 0.000 cytochrome c oxidase 0.000 E-cadherin 0.000 alcohol dehydrogenase 0.000 ribonucleoprotein 0.000 GTP 0.000 protein kinase B 0.000 MCP-1 0.000 Boc 0.000 carbonic anhydrase 0.000 LPS 0.000 JNK 0.000 rhodopsin 0.000 Nrf2 0.000 glial fibrillary acidic protein 0.000 AMP-activated protein kinase 0.000 phosphoprotein 0.000 c-Myc 0.000 prostate-specific antigen 0.000 Sp1 0.000 bcl-2 0.000 PKA 0.000 metalloproteinase 0.000 TLR2 0.000 human leukocyte antigen 0.000 casein 0.000 metallothionein 0.000 protease inhibitor 0.000 amyloid precursor protein 0.000 SDS 0.000 SMA 0.000 p16 0.000 FISH 0.000 beta-glucuronidase 0.000 calcineurin 0.000 Bcl-2 0.000 apoE 0.000 lipoxygenase 0.000 helicase 0.000 heme oxygenase-1 0.000 RhoA 0.000 MAP kinase 0.000 A-I 0.000 caspase-8 0.000 ICD 0.000 olfactory 0.000 MMP-2 0.000 BRCA1 0.000 annexin V 0.000 CD11b 0.000 BRAF 0.000 phospholipase A2 0.000 chymotrypsin 0.000 platelet-derived growth factor 0.000 ERK1 0.000 plasminogen 0.000 THP 0.000 AKT 0.000 aromatase 0.000 myosin 0.000 PI3K 0.000 mitogen-activated protein 0.000 vascular endothelium 0.000 IFN 0.000 GDP 0.000 EGF 0.000 EPA 0.000 c-fos 0.000 epididymal 0.000 AP-1 0.000 Poly 0.000 extracellular signal-regulated kinase 0.000 superoxide dismutase 0.000 acid phosphatase 0.000 insulin-like growth factor 0.000 HER2 0.000 P450 0.000 vascular endothelial growth factor 0.000 ras 0.000 EGFR 0.000 MAPK 0.000 tumor necrosis factor alpha 0.000 albumin 0.000 glycoprotein 0.000 mucin 0.000 lipopolysaccharide 0.000 Cytokine 0.000 thyroid hormone 0.000 GSH 0.000 lipase 0.000 X-linked 0.000 phosphodiesterase 0.000 San 0.000 transferrin 0.000 endonuclease 0.000 interferon-gamma 0.000 ESI 0.000 TOF 0.000 leptin 0.000 cytochrome 0.000 NADH 0.000 ANOVA 0.000 CSF 0.000 CA1 0.000 NADPH 0.000 fused 0.000 mTOR 0.000 lactate dehydrogenase 0.000 reductase 0.000 TNF-alpha 0.000 TNF 0.000 lectin 0.000 IL-2 0.000 nitric oxide synthase 0.000 IgE 0.000

Disease Liddle's syndrome 0.001 SMAX2 0.001 Angelman syndrome 0.001 Juvenile Parkinsonism 0.000 PARK2 0.000 Staring 0.000 CRV 0.000 PARK1 0.000 parkinsonism 0.000 NPHP3 0.000 IBR 0.000 adult brain tumor 0.000 PARK6 0.000 Parkinson's disease 0.000 Azul 0.000 APC 0.000 Dent's disease 0.000 AAA 0.000 riboflavin deficiency 0.000 Canavan 0.000 CYLD 0.000 XPB 0.000 brachycephaly 0.000 EBM 0.000 Heller 0.000 anal atresia 0.000 RP11 0.000 tumorigenesis 0.000 PHP 0.000 LAP 0.000 language disorder 0.000 cancer 0.000 OPA1 0.000 abdominal aortic aneurysm 0.000 Hippel 0.000 RP4 0.000 amyotrophic lateral sclerosis 0.000 molluscum contagiosum 0.000 Spinocerebellar ataxia 0.000 NLS 0.000 acute promyelocytic leukemia 0.000 tumor 0.000 Cholangiocarcinoma 0.000 muscular atrophy 0.000 RDA 0.000 Machado-Joseph disease 0.000 pruritus 0.000 renal hypertension 0.000 leukodystrophy 0.000 synovial sarcoma 0.000 chancroid 0.000 Cholangiocarcinoma 0.000 Anisakis 0.000 uterine cancer 0.000 limb-girdle muscular dystrophy 0.000 Cockayne syndrome 0.000 papilloma 0.000 cervical cancer 0.000 severe mental retardation 0.000 DSS 0.000 multiple myeloma 0.000 esophageal atresia 0.000 Japanese encephalitis 0.000 ARF 0.000 Huntington's disease 0.000 plant disease 0.000 mantle cell lymphoma 0.000 Dementia with Lewy bodies 0.000 lung cancer 0.000 DSS 0.000 mental retardation 0.000 mental retardation 0.000 FBS 0.000 erythroleukemia 0.000 PML 0.000 developmental delay 0.000 Autism spectrum disorder 0.000 carcinogenesis 0.000 breast cancer 0.000 Blocking 0.000 oral cancer 0.000 non-small cell lung cancer 0.000 adult T-cell leukemia/lymphoma 0.000 HGF 0.000 telangiectasia 0.000 viral diarrhea 0.000 metastatic melanoma 0.000 dementia 0.000 retinoblastoma 0.000 coxsackievirus 0.000 achalasia 0.000 motor neuron disease 0.000 xeroderma pigmentosum 0.000 hepatitis A 0.000 hypertension 0.000 gastrointestinal stromal tumor 0.000 MCF 0.000 Rett syndrome 0.000 embryonal carcinoma 0.000 NS3 0.000 stromal tumors 0.000 obsessive-compulsive disorder 0.000 autism 0.000 azoospermia 0.000 cutaneous melanoma 0.000 respiratory failure 0.000 lung carcinoma 0.000 pituitary adenoma 0.000 lymphoblastic leukemia 0.000 Still 0.000 Kaposi's sarcoma 0.000 genetic disorder 0.000 choriocarcinoma 0.000 neurological disease 0.000 scrotum 0.000 CEM 0.000 adenocarcinoma 0.000 hepatic encephalopathy 0.000 neuroblastoma 0.000 lymphoma 0.000 tumor progression 0.000 MAS 0.000 vaccinia 0.000 Cushing's syndrome 0.000 chronic lymphocytic leukemia 0.000 HCG 0.000 neoplastic transformation 0.000 renal cancer 0.000 pancreatic cancer 0.000 male infertility 0.000 Alzheimer's disease 0.000 aggressiveness 0.000 sleep disturbances 0.000 skin cancer 0.000 mimicry 0.000 muscular dystrophy 0.000 colorectal cancer 0.000 uremia 0.000 carcinoma in situ 0.000 carcinoma 0.000 IVF 0.000 chronic lymphocytic leukemia 0.000 mammary tumor 0.000 PDB 0.000 basal cell carcinoma 0.000 Legionella 0.000 squamous cell carcinoma 0.000 Pancreas 0.000 macular degeneration 0.000 Schistosoma mansoni 0.000 Pancreas 0.000 solid tumor 0.000 ulcerative colitis 0.000 Melanoma 0.000 virus infection 0.000 metastatic breast cancer 0.000 SDS 0.000 hematologic malignancies 0.000 liver fibrosis 0.000 WT1 0.000 myocarditis 0.000 periodontal disease 0.000 scoliosis 0.000 glioblastoma multiforme 0.000 ICD 0.000 dilated cardiomyopathy 0.000 prostate cancer 0.000 Epstein 0.000 SCID 0.000 cystic fibrosis 0.000 hepatocellular carcinoma 0.000 epithelial ovarian cancer 0.000 subarachnoid hemorrhage 0.000 Brown 0.000 periodontitis 0.000 herpes simplex 0.000 ATM 0.000 sepsis 0.000 Autism 0.000 glioma 0.000 dermatitis 0.000 dyslipidemia 0.000 bipolar disorder 0.000 dysplasia 0.000 tumor growth 0.000 sepsis 0.000 leukemia 0.000 acute myeloid leukemia 0.000 pancreatitis 0.000 gastric cancer 0.000 cognitive impairment 0.000 metastases 0.000 worms 0.000 GSH 0.000 vascular disease 0.000 melanoma 0.000 immunodeficiency 0.000 heart failure 0.000 chronic disease 0.000 glioblastoma 0.000 cirrhosis 0.000 colitis 0.000 primary tumor 0.000 type 1 diabetes 0.000 cardiomyopathy 0.000 SEM 0.000 adenoma 0.000 Crohn's disease 0.000 confusion 0.000 glaucoma 0.000 inflammatory bowel disease 0.000 dehydration 0.000 plaque 0.000 proteinuria 0.000 schizophrenia 0.000 suicide 0.000 ovarian cancer 0.000 cytomegalovirus 0.000 colon cancer 0.000 cardiovascular disease 0.000 hyperglycemia 0.000 hepatitis 0.000 Hodgkin's disease 0.000 myocardial ischemia 0.000 hepatitis C 0.000 Infection 0.000 hepatitis B 0.000 cold 0.000 malaria 0.000 Mycobacterium 0.000 obesity 0.000 epilepsy 0.000 myocardial infarction 0.000 arthritis 0.000 depression 0.000 tuberculosis 0.000 infectious diseases 0.000 diabetes 0.000 stroke 0.000 HIV 0.000

Symptom ataxic gait 0.000 starvation 0.000 ataxia 0.000 seizures 0.000 cerebellar ataxia 0.000 hypotonia 0.000 tremor 0.000 dystonia 0.000 collapse 0.000 functional recovery 0.000 acidity 0.000 weakness 0.000 overweight 0.000

Drug Parkin 0.001 Parkin 0.001 Jujube 0.000 Pirarubicin 0.000 lysine 0.000 Bortezomib 0.000 TAK 0.000 Dasatinib 0.000 GEO 0.000 CIA 0.000 AMC 0.000 CoCl2 0.000 CoCl2 0.000 Arsenic trioxide 0.000 Ginseng 0.000 CPT-11 0.000 uPA 0.000 Alanine 0.000 Heme 0.000 Taxol 0.000 Retinoic acid 0.000 Kenyan 0.000 Glutathione 0.000 ICI 0.000 nitroglycerin 0.000 caffeine 0.000 NADH 0.000 IL-2 0.000 CSF 0.000 Dermatol 0.000

Enzyme ubiquitin-protein ligase 0.998 ubiquityl-calmodulin synthetase 0.002 proteasome 0.002 5,10-methenyltetrahydrofolate synthetase 0.000 isopeptidase 0.000 aminopeptidase I 0.000 3-hydroxybutyryl-CoA dehydrogenase 0.000 arginyl-tRNA synthetase 0.000 3C protease 0.000 galactinol synthase 0.000 type 1 protein phosphatase 0.000 APC 0.000 S-adenosyl-L-homocysteine hydrolase 0.000 separase 0.000 m-calpain 0.000 trehalase 0.000 IscS 0.000 diacylglycerol kinase 0.000 protein kinase 0.000 chorismate mutase 0.000 IKK 0.000 p80 0.000 cysteine synthase 0.000 3-hydroxyacyl-CoA dehydrogenase 0.000 fatty acid desaturase 0.000 E-2 0.000 RNA polymerase 0.000 leucine aminopeptidase 0.000 glycerol kinase 0.000 TSP-1 0.000 cdc2 0.000 NADH dehydrogenase 0.000 cystathionine beta-synthase 0.000 ECH 0.000 lysozyme 0.000 3-hydroxy-3-methylglutaryl-CoA reductase 0.000 DNA ligase 0.000 DNA ligase 0.000 alpha-ketoglutarate dehydrogenase 0.000 transketolase 0.000 protein phosphatase 2A 0.000 glutathione S-transferase 0.000 complex I 0.000 granzyme B 0.000 TOR 0.000 farnesyltransferase 0.000 PNGase F 0.000 polo-like kinase 1 0.000 ATPase 0.000 enolase 0.000 ERK 0.000 glutaminase 0.000 cathepsin L 0.000 chaperonin 0.000 caspase-3 0.000 hexokinase 0.000 transcriptase 0.000 luciferase 0.000 thioredoxin reductase 0.000 phosphoinositide 3-kinase 0.000 diaphorase 0.000 MDP 0.000 histone acetyltransferase 0.000 calcineurin 0.000 ornithine decarboxylase 0.000 RNase 0.000 ribonuclease 0.000 ribonuclease 0.000 isocitrate dehydrogenase 0.000 mitogen-activated protein kinase 0.000 furin 0.000 ricin 0.000 beta-glucosidase 0.000 PARP 0.000 isocitrate dehydrogenase 0.000 aldolase 0.000 arginase 0.000 CaMKII 0.000 proteinase K 0.000 cathepsin D 0.000 heme oxygenase 0.000 MMP 0.000 topoisomerase 0.000 DNA methyltransferase 0.000 NQO1 0.000 caspase-1 0.000 beta-galactosidase 0.000 caspase-8 0.000 prostate-specific antigen 0.000 ATP synthase 0.000 RNase 0.000 carbonic anhydrase 0.000 caspase-9 0.000 DNase 0.000 beta-glucuronidase 0.000 glucose-6-phosphate dehydrogenase 0.000 protein kinase C 0.000 phospholipase C 0.000 lipoxygenase 0.000 cytochrome oxidase 0.000 topoisomerase 0.000 alcohol dehydrogenase 0.000 CD10 0.000 trypsin 0.000 chymotrypsin 0.000 focal adhesion kinase 0.000 AMPK 0.000 acid phosphatase 0.000 AMP-activated protein kinase 0.000 reverse transcriptase 0.000 phospholipase A2 0.000 superoxide dismutase 0.000 NO synthase 0.000 DNA polymerase 0.000 endonuclease 0.000 lipase 0.000 phosphodiesterase 0.000 lactate dehydrogenase 0.000 renin 0.000 ACS 0.000

Compound Ubiquitin 0.001 Methyl caffeate 0.000 Cbl 0.000 RUB 0.000 3-fluoropyridine 0.000 PYR 0.000 1,4-cyclohexanedione 0.000 Perillyl alcohol 0.000 Perillyl alcohol 0.000 Vinclozolin 0.000 lysine 0.000 Embelin 0.000 ATP 0.000 Arabinogalactan 0.000 DGE 0.000 DGE 0.000 DGE 0.000 PPi 0.000 AAA 0.000 G 1 0.000 SSH 0.000 AICAR 0.000 CHIP 0.000 adenylate 0.000 cysteine 0.000 5-Azacytidine 0.000 aldosterone 0.000 DBT 0.000 Cortisone 0.000 Glycogen synthase 0.000 AF-2 0.000 APH 0.000 DMPP 0.000 Cycloheximide 0.000 Isoform 0.000 Arsenite 0.000 DNA 0.000 AICAR 0.000 methanethiol 0.000 Uracil 0.000 DEP 0.000 3-methylhistidine 0.000 MAD 0.000 Brefeldin A 0.000 Brefeldin A 0.000 malononitrile 0.000 E-64 0.000 retinoic acid 0.000 DEP 0.000 Artemisinin 0.000 arginine 0.000 SN-38 0.000 serine 0.000 tyrosine 0.000 zinc 0.000 40S 0.000 POP 0.000 pyrimidine 0.000 isopentenyl diphosphate 0.000 leucine 0.000 threonine 0.000 Guanine 0.000 sodium 0.000 salt 0.000 CCP 0.000 methionine 0.000 Gly 0.000 Methamphetamine 0.000 Casein 0.000 myricetin 0.000 C2H2 0.000 CPT-11 0.000 ATF 0.000 DTT 0.000 TNM 0.000 AMP 0.000 DTT 0.000 DOC 0.000 BCNU 0.000 Vasopressin 0.000 Ile 0.000 NH2 0.000 alanine 0.000 Leucine 0.000 DEAE 0.000 DPP 0.000 IAA 0.000 GSSG 0.000 Arachidonic acid 0.000 DSS 0.000 Alanine 0.000 MMC 0.000 Dec 0.000 IAA 0.000 nicotinic acid 0.000 nicotinic acid 0.000 aldehyde 0.000 nicotinic acid 0.000 Quercetin 0.000 NAD 0.000 Rapamycin 0.000 succinic acid 0.000 Heme 0.000 aniline 0.000 PDB 0.000 His 0.000 aldehyde 0.000 L-DOPA 0.000 cyanide 0.000 Phe 0.000 NAD 0.000 molybdenum 0.000 nicotinic acid 0.000 ABA 0.000 EMS 0.000 isoleucine 0.000 isoleucine 0.000 GAL 0.000 proline 0.000 MPTP 0.000 hydroxylamine 0.000 HCO 0.000 ABA 0.000 APAP 0.000 pyrrolidine 0.000 hydrazine 0.000 Cortisol 0.000 Asp 0.000 hydroxylamine 0.000 COS 0.000 pyrrolidine 0.000 FK506 0.000 butyric acid 0.000 ubiquinone 0.000 MDA 0.000 butyric acid 0.000 nitrogen 0.000 ICI 0.000 cAMP 0.000 Melatonin 0.000 butyric acid 0.000 quinoline 0.000 quinoline 0.000 GTP 0.000 H2O2 0.000 benzoic acid 0.000 calcium 0.000 Phytol 0.000 Phytol 0.000 adenosylmethionine 0.000 alcohol dehydrogenase 0.000 SDS 0.000 Dopamine 0.000 Collagen 0.000 sulfate 0.000 Cholesterol 0.000 retinol 0.000 ammonium 0.000 THP 0.000 GSH 0.000 GSH 0.000 THP 0.000 nitric oxide 0.000 salicylic acid 0.000 GDP 0.000 glucose 0.000 Mg2+ 0.000 uridine 0.000 ethyl acetate 0.000 valine 0.000 hexane 0.000 cadmium 0.000 tryptophan 0.000 tryptophan 0.000 tryptophan 0.000 urea 0.000 glutamic acid 0.000 glutamate 0.000 boron 0.000 tryptophan 0.000 bromide 0.000 TOF 0.000 caffeine 0.000 NADH 0.000 NADPH 0.000 NADPH 0.000 silver 0.000 glutamine 0.000 TNF 0.000 titanium 0.000 nickel 0.000 5-HT 0.000 MTT 0.000 galactose 0.000 Pac 0.000 water 0.000 GABA 0.000 manganese 0.000 iron 0.000 GABA 0.000 glycerol 0.000 phosphorus 0.000 iodine 0.000 creatinine 0.000 methanol 0.000 ethanol 0.000 ACS 0.000 ACS 0.000 hydrogen 0.000 oxygen 0.000 Clin 0.000 Cardiol 0.000 phosphate 0.000 BMC 0.000

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