Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.19 (ubiquitin-protein ligase)
 799 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Ubiquitin-like modifier activating enzyme 1 15.3
KIAA0675 15.3
hect domain and RLD 5 15.3
ubiquitin-protein ligase 15.3
Ubiquitin-protein ligase 15.3
ANKRD13D 15.3
ANKRD13A 15.3
FBL7 15.3
ANKRD13B 15.3
Praja-1 14.7
KIAA0554 14.3
5'-3' exoribonuclease 2 14.3
arrestin domain containing 4 14.3
C1QL4 14.3
40S ribosomal protein S3a 14.3
NEDD4 protein 14.0
E2-F1 13.9
UFD2 13.7
RFPL4 13.7
ubiquitin-like modifier activating enzyme 3 13.7
DRIP1 13.7
Cellular tumor antigen p53 13.7
DnaJ/Hsp40 chaperone 13.7
RSP5 13.5
coactivator for steroid receptors 13.3
ZNF645 13.3
Ring finger protein 1 13.3
UBA6 13.3
HIRIP3 13.3
sideroflexin 2 13.3
FBXO17 13.3
PMEPA1 protein 13.3
DRIP2 13.3
CDC26 13.1
KDELR3 13.0
EIF-5A 13.0
TOP1 protein 13.0
SMAX2 13.0
RNF128 13.0
chromodomain helicase DNA binding protein 2 13.0
FKBP3 13.0
Vaccinia-related kinase 3 13.0
WBP-1 13.0
ubiquitin carrier protein 12.9
FBG3 12.7
RNF206 12.7
RNF186 12.7
arginyl-tRNA-protein transferase 12.7
ADP-ribosylation factor domain protein 1 12.7
UBC4 12.6
UBA1 12.5
seven in absentia homolog 2 12.5
SWM1 12.5
FBXO6 12.5
FBXO27 12.5
ubiquitin thiolesterase 12.5
HERC1 12.5
APC11 12.3
E6-AP 12.3
AHNAK protein 12.3
Multidrug resistance protein 3 12.3
heterogeneous nuclear ribonucleoprotein A3 12.3
CGR19 12.3
CPSF7 12.3
RNF26 12.3
UBE1 12.3
USE1 12.2
PHP2 12.1
Ubiquitin-activating enzyme 12.1
TINO 12.1
TOMM22 12.1
ARRDC4 12.1
UBE1L 12.1
RuvB-like 2 12.1
nucleolar and coiled-body phosphoprotein 1 12.1
EF1B 12.1
VPS13D 12.1
PAIP1 12.1
UbcH7 12.1
ARIH1 12.0
WW domain binding protein 2 12.0
NTKL 12.0
insulin induced gene 1 12.0
rpl11 12.0
RNF139 12.0
DZIP3 12.0
Nedd4-2 11.9
CCNF 11.9
ubiquitin-conjugating enzyme 11.9
HELZ 11.8
SPINK2 11.8
SALL4B 11.8
RAI3 11.8
UBP43 11.7
TRIM36 11.7
FBL3 11.7
FBG1 11.6
E2 ubiquitin-conjugating enzyme 11.6
MEX67 11.6
MAGE-D 11.6
TPRD 11.6
MDP1 11.6
UbcH8 11.6
HACE1 11.6
cbl-b 11.5
E6TP1 11.5
Layilin 11.5
RNF41 11.5
RTF1 11.5
Uba5 11.4
Doc1 11.4
TRIP12 11.4
GRIP2 11.4
CDC16 11.4
cdc2-related protein kinase 11.4
APC8 11.4
ubiquitin-fold modifier 1 11.4
cyclin F 11.3
MYCBP2 11.3
E6AP 11.3
AIP2 11.3
RING-IBR 11.3
HBZ protein 11.2
PCTK1 11.2
FAP48 11.2
CDC23 11.2
UBE2G2 11.2
PIRH2 11.2
Ubc6p 11.2
WWP2 11.1
RING-H2 11.1
SLC25A5 11.1
LDOC1 11.1
Ufc1 11.1
HSJ1a 11.1
TMX1 11.0
MTMR4 11.0
STAM-1 11.0
AGP1 11.0
ARAF1 11.0
PDZRN3 11.0
UBE3A 11.0
UBE2D1 11.0
UBA3 11.0
Ubiquitin carboxyl-terminal hydrolase 11.0
transformation/transcription domain-associated protein 11.0
RNF144A 11.0
APC10 11.0
NOT4 11.0
UbcH6 10.9
UBR1 10.9
UBE2G1 10.9
TRAIP 10.9
UBE3A protein 10.9
PSMD1 10.9
RNF40 10.9
FAT10 10.8
sigma 3 protein 10.8
formin-like 1 10.8
YAP65 10.8
UBE2O 10.8
FBXW8 10.8
UFM1 10.8
PDS5 10.8
Pop1 10.7
PICT-1 10.7
SALL3 10.7
GORAB 10.6
MTHFS 10.6
VCY2 10.6
TRAF-interacting protein 10.6
APP-BP1 10.6
AKAP3 10.6
PSMD7 10.5
UHRF2 10.5
UBE2M 10.5
UBE2H 10.5
PSMD14 10.5
RNF216 10.5
UBA2 10.4
ubiquitin-activating enzyme E1 10.4
MMS2 10.4
NEDD4-2 10.4
SHFM3 10.4
synphilin-1 10.4
UBE2L3 10.4
AE4 10.4
ubiquitin-protein isopeptide ligase (E3) 10.4
PSMC4 10.3
Ubiquitin-conjugating enzyme 10.3
sentrin-specific protease 10.3
NPH3 10.3
RIG1 10.3
putative E3 ubiquitin ligase 10.3
TOPORS 10.2
TOM70 10.2
PSMA1 10.2
HNRNPK 10.2
kinase-like protein 10.2
UBC7 10.2
HOIL-1 10.1
UBC2 10.1
RPS4X 10.1
EEF2 10.1
parkin 10.1
cAMP responsive element modulator 10.1
GSPT1 10.1
HUWE1 10.0
NYGGF4 10.0
SRP14 10.0
myeloid zinc finger 1 10.0
BRUCE 10.0
E3 protein 10.0
UBR5 10.0
ubiquitin-like protein Nedd8 10.0
UBR4 10.0
NLRP2 10.0
NEDD4L 10.0
ubiquitin-protein isopeptide ligase 9.9
CSE1 9.9
RING finger protein 9.9
RBBP8 9.9
NEDD4 9.8
E6 protein 9.8
Parkin 9.8
brca2 9.8
FLRF 9.8
HMGCS1 9.8
RPN2 9.8
GPX7 9.8
LNX 9.8
ubiquitin-conjugating enzyme E2 9.8
APC1 9.8
PMEPA1 9.8
Derlin-2 9.7
RNF11 9.7
UBC9 9.7
UQCRC1 9.7
TNF receptor-associated factor 3 9.7
NDUFS2 9.7
USP22 9.7
elongin C 9.7
p53-binding protein 9.6
POSH 9.6
RING1A 9.6
GREM2 9.6
HSD17B10 9.6
BI-1 9.6
diubiquitin 9.6
Voltage-gated sodium channel 9.6
NEDD4-1 9.6
RING1 9.5
SPT6 9.5
PARKIN 9.5
NPI-1 9.5
Sharpin 9.5
RCC1-like 9.5
SFT 9.5
ring finger protein 9.4
RP-A 9.4
SRP9 9.4
PTPRJ 9.4
SAE1 9.4
sperm surface protein 9.4
Pellino 9.4
PTPRG 9.4
TOP2B 9.3
SUG1 9.3
PARK2 9.3
SKP2 9.3
arginyl-tRNA synthetase 9.3
acrosin inhibitor 9.3
+Ca 9.3
amino acid permease 9.3
DIAP1 9.3
Skp1 9.3
ARD1 9.3
INSIG1 9.3
NCK1 9.3
CDC27 9.2
RBX1 9.2
SAE2 9.2
ribosomal protein L11 9.2
Cullin-1 9.2
IMPDH2 9.2
Mule 9.2
TOM1 9.2
scribble 9.2
USP18 9.2
finger protein 9.2
par-4 9.2
Grp170 9.2
DNAJB6 9.2
CCR4-NOT 9.1
TCR zeta chain 9.1
eps15 9.1
LRPPRC 9.1
Sec62 9.1
TRIM21 9.1
MGD1 9.1
cell cycle-related protein 9.1
TPI1 9.1
ubiquitin 9.1
CRV 9.1
RNF43 9.0
1C5 9.0
XRN2 9.0
CHD2 9.0
securin 9.0
ubiquitin fusion protein 9.0
cullin 3 9.0
CDC20 9.0
BMP10 9.0
sentrin 9.0
Ubiquitin 9.0
RBP1 9.0
ORP150 9.0
EF1A 9.0
USP10 9.0
Ubc13 9.0
UBB 9.0
POMP 9.0
PSP94 8.9
PPP2R1A 8.9
gp78 8.9
Ankyrin 8.9
ENaC 8.9
ubiquitin C 8.9
NEDD8 8.9
ClC-5 8.9
EPHB2 8.9
Hsp70-interacting protein 8.9
HLA-F 8.8
hepatocyte growth factor-regulated tyrosine kinase substrate 8.8
efp 8.8
protein phosphatase 2 8.8
TRIM24 8.8
RNF20 8.8
PRDX6 8.8
GRAIL 8.8
ubiquitin conjugating enzyme 8.8
WW domain-containing 8.8
RNF168 8.8
ubiquitin-like protein 8.8
barttin 8.8
LBP-1 8.8
UT-A2 8.8
RNF213 8.8
CUL4B 8.8
USP8 8.7
Mex67 8.7
anaphase-promoting complex/cyclosome 8.7
SHARPIN 8.7
p53 binding protein 8.7
VACM-1 8.7
TRIM32 8.7
p32) 8.7
Derlin-1 8.6
JAB1 8.6
ubiquitin-conjugating enzyme 9 8.6
CRBN 8.6
ubiquitin ligase 8.6
Itch 8.6
CUL1 8.6
eIF-3 8.5
Rbx1 8.5
Rpn13 8.5
UBE2C 8.5
HSPD1 8.5
F-box protein 8.5
Cdc48 8.5
ECT2 8.5
AHNAK 8.5
CHFR 8.5
CLCN5 8.5
SALL1 8.5
CIN85 8.5
Hdm2 8.5
zinc metallopeptidase 8.5
septin 8.5
iron regulatory protein 2 8.4
calcium-independent phospholipase A2 8.4
cullin 8.4
RBCC 8.4
EDD 8.4
PINK1 8.4
SKP1 8.4
ARI 8.4
WD-repeat protein 8.4
RanBP2 8.4
ERN1 8.4
RING-finger protein 8.4
UCH-L1 8.4
hnRNP D 8.3
NURR1 8.3
HOXA1 8.3
spliceosomal protein 8.3
MAP1LC3B 8.3
DGK 8.3
CCND3 8.2
TRRAP 8.2
KEN 8.2
YWHAE 8.2
Elongin B 8.2
HRD1 8.2
gene 4 8.2
UBC 8.2
granulocyte colony-stimulating factor receptor 8.2
HERC2 8.2
histone H2B 8.2
ubiquitin-specific protease 8.1
proteasome 8.1
PSAP 8.1
Gab2 8.1
UBC13 8.1
ubiquitin protease 8.1
CUL3 8.1
calcium-activated neutral protease 8.1
Fe65 8.1
lysosome-associated membrane protein-2 8.1
ATXN2 8.1
PHR1 8.1
atrogin-1 8.1
FANCJ 8.1
SCF 8.0
ubiquitin carboxyl-terminal hydrolase 8.0
SUMO2 8.0
thioredoxin interacting protein 8.0
S-adenosyl-L-homocysteine hydrolase 8.0
HBZ 8.0
AIF4 8.0
RNF4 8.0
Skp2 8.0
tropomodulin 8.0
AP180 8.0
ACAT2 7.9
HDM2 7.9
TSG101 7.9
GABRB3 7.9
ZFX 7.9
FAT1 7.9
HSF2 7.9
CARD9 7.9
Mdm2 7.9
helicase II 7.9
COP9 7.9
BMF 7.8
NACP 7.8
sugar transporter 7.8
ribosomal protein S6 kinase 1 7.8
CUL4 7.8
KIP1 7.8
glycine-rich protein 7.8
BMP9 7.8
FBA 7.8
Rpn10 7.8
NAIP 7.8
RAD1 7.8
PARK6 7.8
MFF 7.8
SRP54 7.8
TIP60 7.8
TEK 7.8
RECK 7.7
MTA1 7.7
CASK 7.7
VHL protein 7.7
TRIP 7.7
carboxylating 7.7
synexin 7.7
CBL 7.7
HDEL 7.6
KAI1 7.6
ELK1 7.6
P29 7.6
HAND1 7.6
proteasome inhibitor 7.6
heterogeneous nuclear ribonucleoprotein K 7.6
Cap43 7.6
FBXW7 7.6
ficolin 7.6
BRIP1 7.5
RLR 7.5
geminin 7.5
deubiquitinating enzyme 7.5
p27Kip1 7.5
protein phosphatase 2C 7.5
PWI 7.5
TRIM25 7.5
ubiquitin C-terminal hydrolase 7.5
UCHL1 7.5
CKB 7.5
MTH1 7.5
retinal protein 7.4
LIG4 7.4
dishevelled 7.4
HIF-1beta 7.4
GW182 7.4
dentatorubral-pallidoluysian atrophy 7.4
MAD2 7.4
Proteasome 7.4
ataxin-1 7.4
TRIM 7.4
YWHAZ 7.4
pericentrin 7.4
Id4 7.4
RNF8 7.4
cereblon 7.4
ISG15 7.4
TXNIP 7.3
SC35 7.3
synaptojanin 7.3
CYLD 7.3
gamma-tubulin 7.3
thymopoietin 7.3
lactotransferrin 7.3
ephrin-B1 7.3
SGK1 7.3
HNA 7.3
MuRF 7.3
CRABP 7.2
E1B 7.2
E3 ubiquitin ligase 7.2
coilin 7.2
Nav1.5 7.2
kelch 7.2
cysteine desulfurase 7.2
TOP1 7.2
IL23R 7.2
spinocerebellar ataxia type 2 7.1
R12 7.1
DRP1 7.1
pVHL 7.1
GAT1 7.1
optineurin 7.1
Phosphatase and tensin homolog 7.1
histone H2A 7.1
FKBP51 7.1
NADH-ubiquinone oxidoreductase 7.1
aryl hydrocarbon receptor nuclear translocator 7.1
CHIP 7.1
peptidoglycan recognition protein 7.1
AF-1 7.1
mitofusin 2 7.1
p45 7.1
MAPK3 7.0
SLUG 7.0
REDD1 7.0
promyelocytic leukemia protein 7.0
PDE2 7.0
aldolase B 7.0
MDC1 7.0
melanocortin 1 receptor 7.0
caspase 6 7.0
CtIP 7.0
MICB 7.0
seminal plasma protein 7.0
ATG16L1 7.0
XPB 7.0
Atrogin-1 6.9
p105 6.9
Sp1 protein 6.9
partial protein 6.9
beta-spectrin 6.9
RasGAP 6.9
CCL7 6.9
DAN 6.9
antizyme 6.9
NFE2L2 6.9
ATG7 6.9
potential tumor suppressor 6.8
A-kinase anchoring protein 6.8
CRL4 6.8
Dnmt3b 6.8
cIAP2 6.8
p97 6.8
Id3 6.8
coiled-coil protein 6.7
activating transcription factor 6 6.7
LMO2 6.7
Zap 6.7
IkappaB kinase 6.7
cyclin-dependent kinase inhibitor p27 6.7
SLI 6.7
alpha-synuclein 6.7
GAP43 6.7
serine/threonine-protein kinase 6.7
dynamin-related protein 1 6.7
farnesyl diphosphate synthase 6.7
AICAR 6.7
pendrin 6.7
truncated variant 6.7
Ro52 6.7
FKBP52 6.7
separase 6.7
extracellular signal regulated kinase 6.7
BIRC5 6.6
Cyclin 6.6
PGK1 6.6
p27(KIP1) 6.6
MOT 6.6
histone deacetylase 6 6.6
X-linked inhibitor of apoptosis protein 6.6
transgelin 6.6
Set1 6.6
PABP 6.6
KCa3.1 6.6
Pin1 6.6
CIA 6.5
anion transporter 6.5
DDB1 6.5
HMG-CoA synthase 6.5
endoprotease 6.5
IRAK1 6.5
RP11 6.5
PKC zeta 6.5
NOTCH3 6.5
activating transcription factor 3 6.5
AQP2 6.5
MuRF1 6.5
trehalase 6.5
SUMO1 6.4
VCP 6.4
DBT 6.4
Hsp40 6.4
SMAD3 6.4
Toll/interleukin-1 receptor 6.4
TRF1 6.4
LRRK2 6.4
US2 6.4
p20 6.4
cyclin 6.3
AAA 6.3
regucalcin 6.3
aldolase A 6.3
Tom40 6.3
APC 6.3
EF-Tu 6.3
cIAP1 6.3
BP1 6.3
LAP 6.3
PHP 6.3
collecting duct 6.3
p32 6.2
TFE3 6.2
zinc finger motif 6.2
E2 protein 6.2
XIAP 6.2
O6-methylguanine-DNA methyltransferase 6.2
NPR1 6.2
processed form 6.2
MAPK1 6.2
PRC1 6.2
expressed in testis 6.2
p80 6.2
Hexokinase 6.2
lysosomal protein 6.2
nuclear factor of activated T-cells 6.2
Dnmt3a 6.2
FHIT 6.2
RAD50 6.2
squalene synthase 6.2
OPA1 6.1
CCAAT/enhancer-binding protein homologous protein 6.1
granzyme A 6.1
Brca1 6.1
TAK 6.1
Occludin 6.1
tumor suppressor protein 6.1
COL3A1 6.1
polo-like kinase 1 6.1
transcription repressor 6.1
CIP1/WAF1 6.1
ARNT 6.1
zinc transporter 6.1
MDM2 6.1
Mad2 6.1
p73 6.1
ataxin-3 6.0
NEP 6.0
Glycogen synthase 6.0
CIC 6.0
L11 6.0
78 kDa 6.0
DNMT3A 6.0
leucine-rich repeat kinase 2 6.0
MRE11 6.0
TOP2A 6.0
glycerol kinase 6.0
mdm2 6.0
DJ-1 6.0
H2A 6.0
alpha-ketoglutarate dehydrogenase 6.0
HDAC4 6.0
single-stranded DNA-binding protein 6.0
Id1 5.9
PAK1 5.9
RAD52 5.9
RIP1 5.9
inhibitor of apoptosis 5.9
VHL 5.9
SUMO-1 5.9
poly(A)-binding protein 5.9
p90 5.9
proline-rich 5.9
ASK1 5.9
53BP1 5.9
HIS3 5.9
organic anion transporter 5.9
HSF1 5.9
IkappaBalpha 5.9
LC3B 5.8
H2B 5.8
N-myc 5.8
novel gene 5.8
caveolin-3 5.8
guanine nucleotide binding protein 5.8
ICAM-3 5.8
MDA5 5.8
SMAD4 5.8
nuclear hormone receptor 5.8
14-3-3 5.8
4EBP1 5.8
RP4 5.8
interacting protein 5.8
NBS1 5.8
DICER1 5.8
linker histone 5.8
cyclin-dependent kinase inhibitor 5.8
HA2 5.7
GDF15 5.7
TFIIH 5.7
diacylglycerol kinase 5.7
promyelocytic leukemia 5.7
Notch3 5.7
p14 5.7
APH 5.7
mitochondrial ATPase 5.7
p34 5.7
eukaryotic translation initiation factor 5.7
GEF 5.7
Transporter 5.7
nucleolar protein 5.6
cytochrome P450 2E1 5.6
PEST 5.6
TRAF6 5.6
MSV 5.6
prolyl isomerase 5.6
Huntingtin 5.6
elongation factor 2 5.6
Dnmt1 5.6
MAD 5.6
dynactin 5.6
SHP 5.6
ADP-ribosylation factor 5.6
ARF 5.6
L12 5.5
Kir2.1 5.5
Cyclin-dependent kinase 5.5
cyclin D3 5.5
ribosomal S6 kinase 5.5
DNA repair protein 5.5
adapter protein 5.5
sodium channel 5.5
B protein 5.5
fetal kidney 5.5
protein-tyrosine phosphatase 5.5
GAL1 5.5
serine/threonine protein kinase 5.5
LAT 5.5
TM3 5.5
AP-2 5.5
protein-tyrosine kinase 5.5
TDP-43 5.5
cyclin-dependent kinase 5.4
metallopeptidase 5.4
heat shock protein 90 5.4
cyclin B1 5.4
syntaxin 5.4
FKBP12 5.4
metastasis suppressor 5.4
interferon regulatory factor 3 5.4
SRC-1 5.4
Yes 5.4
PKS 5.4
E2F-1 5.4
ATF6 5.4
adenomatous polyposis coli 5.4
GAL 5.4
TM1 5.3
DIABLO 5.3
adipose triglyceride lipase 5.3
p62 5.3
calpain 5.3
retinoic acid receptor alpha 5.3
homeodomain transcription factor 5.3
TRIF 5.3
NADH dehydrogenase 5.3
Axin 5.3
Creatine kinase 5.3
RNase A 5.3
BiP 5.3
KCNQ1 5.3
RNA polymerase II 5.3
DNA repair enzyme 5.3
S10 5.3
chimeric protein 5.2
C protein 5.2
Smac 5.2
like kinase 5.2
HSP60 5.2
ataxia telangiectasia mutated 5.2
serine/threonine kinase 5.2
CK2 5.2
Apaf-1 5.2
HA1 5.2
N-glycanase 5.2
GTPase-activating protein 5.2
endoglin 5.2
transcriptional activator 5.2
cdk2 5.2
p27 5.2
chloride channel 5.2
PTEN 5.2
MPN 5.1
HSD1 5.1
PGP 9.5 5.1
PML 5.1
small GTPase 5.1
signal recognition particle 5.1
SUMO 5.1
Rab7 5.1
c-fms 5.1
ALA 5.1
MCP-3 5.1
calpastatin 5.1
tensin 5.1
voltage-gated sodium channel 5.1
Cu/Zn superoxide dismutase 5.0
S100A8 5.0
NHE1 5.0
FGF8 5.0
vascular endothelial growth factor receptor 2 5.0
MMR 5.0
casein kinase 5.0
PDB 5.0
alpha, beta 5.0
transketolase 4.9
DNMT3B 4.9
H2AX 4.9
p11 4.9
EST) 4.9
p53 4.9
spleen tyrosine kinase 4.9
CDK6 4.9
quinone oxidoreductase 4.9
MYB 4.9
TOR 4.9
SCD1 4.9
pRb 4.9
Chk2 4.8
IAP 4.8
CDH1 4.8
p17 4.8
DSS 4.8
agouti 4.8
ankyrin 4.8
CIS 4.8
all-trans 4.7
C2H2 4.7
MyoD 4.7
VIM 4.7
nuclear protein 4.7
DEAD 4.7
testis-specific 4.7
zinc finger 4.7
Smad1 4.7
cyclin dependent kinase 4.6
pyrophosphatase 4.6
DNA ligase 4.6
PARP1 4.6
adaptor protein 4.6
C/EBP homologous protein 4.6
SRC 4.6
protein disulfide isomerase 4.6
p12 4.6
tRNA 4.6
ERBB2 4.6
interferon-beta 4.6
dynamin 4.5
c-MYC 4.5
Epidermal growth factor receptor 4.5
factor H 4.5
protein phosphatase 4.5
mineralocorticoid receptor 4.5
FBS 4.5
Aurora-A 4.5
Hsp60 4.5
unknown function 4.5
histone methyltransferase 4.5
CMS 4.5
MIM 4.5
pepsinogen 4.5
troponin T 4.5
BMP2 4.5
Histone deacetylase 4.5
enolase 4.5
titin 4.5
INS-1 4.5
PERK 4.4
splicing factor 4.4
DNA polymerase alpha 4.4
cyclin A 4.4
glutaminase 4.4
granzyme B 4.4
zinc finger protein 4.4
P19 4.4
TLR9 4.4
FGFR1 4.4
thyroid hormone receptor 4.4
DNA binding protein 4.4
muscle protein 4.4
ATF 4.4
inward rectifier 4.4
AAG 4.4
platelet-derived growth factor receptor 4.4
poly (ADP-ribose) polymerase 4.3
cathepsin L 4.3
tumour suppressor 4.3
motor protein 4.3
HIF-1alpha 4.3
MDP 4.3
p55 4.3
glucocerebrosidase 4.3
alpha-tubulin 4.3
PKR 4.3
SOD1 4.3
outer mitochondrial membrane 4.3
GTP-binding protein 4.3
histone H3 4.2
SP1 4.2
EZH2 4.2
myostatin 4.2
PP1 4.2
leucine zipper 4.2
ribonuclease A 4.2
chaperonin 4.2
alpha-actinin 4.2
LC3 4.2
phosphatase and tensin homolog 4.2
hepatocyte growth factor 4.2
methylguanine-DNA methyltransferase 4.2
manganese superoxide dismutase 4.2
NQO1 4.1
HDAC1 4.1
Epidermal growth factor 4.1
p50 4.1
Bid 4.1
RIG-I 4.1
CLL 4.1
cyclin E 4.1
p15 4.1
autoantigen 4.1
endoplasmic reticulum 4.1
GST 4.1
hormone receptor 4.1
major histocompatibility complex class I 4.1
thioredoxin reductase 4.1
matrix protein 4.0
c-Met 4.0
MIB 4.0
E2F1 4.0
tumor necrosis factor receptor 4.0
calreticulin 4.0
IKK 4.0
cathepsin 4.0
CPR 4.0
hedgehog 4.0
retinoic acid receptor 4.0
MyD88 4.0
histone acetyltransferase 4.0
PARP-1 4.0
HGF 4.0
DAG 4.0
enigma 4.0
ATP 4.0
cytokine receptor 4.0
transcriptional regulator 3.9
HSP70 3.9
hexokinase 3.9
MYC 3.9
lysozyme 3.9
DNMT1 3.9
HEK 3.9
TNM 3.9
dystrophin 3.9
core protein 3.9
TLR7 3.9
proto-oncogene 3.9
MLR 3.9
JAK2 3.9
cytoplasmic protein 3.9
GABA(A) receptor 3.9
synuclein 3.8
MnSOD 3.8
DPP 3.8
Janus kinase 3.8
histone H1 3.8
bFGF 3.8
CD105 3.8
galectin-3 3.8
cadherin 3.8
CaMKII 3.8
DNA-dependent protein kinase 3.8
Met 3.8
INK4a 3.8
GTPase 3.8
hsp70 3.8
Chk1 3.8
phosphoinositide 3-kinase 3.8
isocitrate dehydrogenase 3.8
C-terminal peptide 3.8
VP2 3.7
nuclear receptor 3.7
arrestin 3.7
P21 3.7
receptor tyrosine kinase 3.7
sky 3.7
prion 3.7
protein C 3.7
ornithine decarboxylase 3.7
flavoprotein 3.7
cyclin D1 3.6
proliferating cell nuclear antigen 3.6
D. melanogaster 3.6
p63 3.6
TRAIL 3.6
pol 3.6
mutant p53 3.6
ALS 3.6
epidermal growth factor receptor 3.6
STAT5 3.6
H-ras 3.6
sonic hedgehog 3.6
DNA gyrase 3.6
A-T 3.5
vascular endothelial growth factor A 3.5
ERK2 3.5
calmodulin 3.5
K12 3.5
vinculin 3.5
progesterone receptor 3.5
RACE 3.5
occludin 3.5
galanin 3.5
transmembrane protein 3.5
ryanodine receptor 3.5
transcriptional factor 3.4
X-chromosome 3.4
aminopeptidase 3.4
type I interferon 3.4
MMP 3.4
topoisomerase I 3.4
serotonin transporter 3.4
PGC 3.4
c-Jun 3.4
Rho 3.4
cystic fibrosis transmembrane conductance regulator 3.4
CDK4 3.3
MAS 3.3
neu 3.3
KIT 3.3
FK506 3.3
vitronectin 3.3
short form 3.3
G protein-coupled receptor 3.3
MET 3.2
membrane protein 3.2
beta-catenin 3.2
Fas ligand 3.2
PC3 3.2
DNA methyltransferase 3.2
crystallin 3.2
STAT 3.2
Fas 3.2
glutathione S-transferase 3.2
peroxisome proliferator-activated receptor 3.2
cysteine protease 3.1
peptidase 3.1
cathepsin D 3.1
ribosomal protein 3.1
heat shock protein 3.1
vimentin 3.1
p65 3.1
poly(ADP-ribose) polymerase 3.1
caspase-9 3.1
interleukin-6 3.1
RNA-binding protein 3.1
ABO 3.1
tropomyosin 3.1
survivin 3.0
envelope glycoprotein 3.0
erythropoietin 3.0
ATPase 3.0
aryl hydrocarbon receptor 3.0
NAD 3.0
cell adhesion molecule 3.0
trypsin inhibitor 3.0
MHC class I 3.0
tau protein 3.0
c-myc 2.9
PC-3 2.9
HMG-CoA reductase 2.9
PARP 2.9
CCL2 2.9
TLR4 2.9
ART 2.9
ubiquinone 2.9
p38 mitogen-activated protein kinase 2.9
MMP-9 2.9
telomeric 2.9
estrogen receptor 2.8
apolipoprotein B 2.8
histone 2.8
phosphatase 2.8
fur 2.8
methyltransferase 2.8
AMP 2.8
Ki-67 2.8
cytochrome c 2.7
phosphorylating 2.7
neurotrophin 2.7
cage 2.7
cAMP-dependent protein kinase 2.7
spermatozoa 2.7
ferredoxin 2.7
STAT3 2.7
interleukin-4 2.7
catenin 2.7
threonine 2.7
glucose-6-phosphate dehydrogenase 2.7
plasminogen activator inhibitor-1 2.7
EGF receptor 2.7
IVF 2.6
serum protein 2.6
ERK 2.6
polypeptide 2.6
caspase-3 2.6
Dictyostelium 2.6
cytochrome c oxidase 2.6
alcohol dehydrogenase 2.6
Mol 2.6
androgen receptor 2.5
SOD 2.5
ribonucleoprotein 2.5
interferon 2.5
protein kinase B 2.5
p21 2.5
MCP-1 2.5
Boc 2.5
erythroid 2.5
carbonic anhydrase 2.5
tyrosine kinase 2.5
rhodopsin 2.4
membrane-bound 2.4
Nrf2 2.4
p38 2.4
AMP-activated protein kinase 2.4
phosphoprotein 2.4
c-Myc 2.4
prostate-specific antigen 2.4
Sp1 2.4
mast cell 2.4
bcl-2 2.4
PKA 2.4
metalloproteinase 2.4
E-cadherin 2.4
TLR2 2.4
vasopressin 2.4
human leukocyte antigen 2.3
metallothionein 2.3
protease inhibitor 2.3
dimeric 2.3
SMA 2.3
p16 2.3
JNK 2.3
FISH 2.3
beta-glucuronidase 2.3
glial fibrillary acidic protein 2.3
cytochrome P450 2.3
calcineurin 2.2
apoE 2.2
lipoxygenase 2.2
helicase 2.2
heme oxygenase-1 2.2
RhoA 2.2
MAP kinase 2.2
casein 2.2
A-I 2.2
caspase-8 2.2
ICD 2.2
amyloid precursor protein 2.1
MMP-2 2.1
GTP 2.1
BRCA1 2.1
annexin V 2.1
CD11b 2.1
BRAF 2.1
LPS 2.0
tumor necrosis factor 2.0
phospholipase A2 2.0
chymotrypsin 2.0
platelet-derived growth factor 2.0
plasminogen 2.0
THP 2.0
aromatase 1.9
mitogen-activated protein 1.9
vascular endothelium 1.9
GDP 1.9
EGF 1.8
EPA 1.8
Bcl-2 1.8
c-fos 1.8
epididymal 1.8
AP-1 1.8
ERK1 1.8
AKT 1.8
myosin 1.8
PI3K 1.8
Poly 1.8
extracellular signal-regulated kinase 1.7
olfactory 1.7
acid phosphatase 1.7
insulin-like growth factor 1.7
SDS 1.7
HER2 1.7
P450 1.6
cytokine 1.6
ras 1.5
EGFR 1.5
tumor necrosis factor alpha 1.5
IFN 1.5
NMR 1.4
mucin 1.4
vascular endothelial growth factor 1.4
MAPK 1.3
Cytokine 1.3
thyroid hormone 1.3
superoxide dismutase 1.3
lipase 1.2
X-linked 1.2
phosphodiesterase 1.2
San 1.1
transferrin 1.1
endonuclease 1.1
interferon-gamma 1.1
GSH 1.1
ESI 1.0
albumin 1.0
glycoprotein 1.0
TOF 1.0
lipopolysaccharide 0.9
leptin 0.9
cytochrome 0.9
NADH 0.9
ANOVA 0.8
CSF 0.8
CA1 0.7
NADPH 0.7
mTOR 0.6
lactate dehydrogenase 0.6
reductase 0.6
TNF-alpha 0.6
lectin 0.5
IL-2 0.5
fused 0.4
nitric oxide synthase 0.4
TNF 0.4
IgE 0.3
GABA 0.2
Disease
SMAX2 13.3
Juvenile Parkinsonism 11.8
Liddle's syndrome 11.4
Staring 10.6
CRV 10.0
PARK1 9.9
Angelman syndrome 9.5
PARK2 9.3
NPHP3 9.1
adult brain tumor 8.7
PARK6 8.6
IBR 8.5
Azul 8.4
Dent's disease 8.0
riboflavin deficiency 7.1
Canavan 7.0
CYLD 6.9
XPB 6.9
brachycephaly 6.9
EBM 6.7
anal atresia 6.6
RP11 6.5
Heller 6.5
parkinsonism 6.3
AAA 6.3
PHP 6.3
LAP 6.1
language disorder 6.0
APC 6.0
OPA1 5.9
RP4 5.8
molluscum contagiosum 5.7
Spinocerebellar ataxia 5.7
NLS 5.6
Cholangiocarcinoma 5.5
RDA 5.5
Machado-Joseph disease 5.5
renal hypertension 5.5
leukodystrophy 5.4
chancroid 5.4
Cholangiocarcinoma 5.3
Anisakis 5.3
uterine cancer 5.2
synovial sarcoma 5.2
Hippel 5.1
limb-girdle muscular dystrophy 5.1
Cockayne syndrome 5.1
Parkinson's disease 4.9
severe mental retardation 4.8
DSS 4.8
abdominal aortic aneurysm 4.8
esophageal atresia 4.8
acute promyelocytic leukemia 4.7
plant disease 4.6
muscular atrophy 4.6
Japanese encephalitis 4.6
Dementia with Lewy bodies 4.6
papilloma 4.5
DSS 4.5
FBS 4.5
mantle cell lymphoma 4.5
ARF 4.3
erythroleukemia 4.3
pruritus 4.3
Autism spectrum disorder 4.3
amyotrophic lateral sclerosis 4.2
PML 4.2
adult T-cell leukemia/lymphoma 4.0
HGF 3.9
telangiectasia 3.9
viral diarrhea 3.9
developmental delay 3.9
Huntington's disease 3.9
tumorigenesis 3.9
oral cancer 3.8
coxsackievirus 3.8
achalasia 3.8
motor neuron disease 3.8
xeroderma pigmentosum 3.8
Blocking 3.7
gastrointestinal stromal tumor 3.7
metastatic melanoma 3.7
cervical cancer 3.7
mental retardation 3.7
mental retardation 3.6
hepatitis A 3.6
Rett syndrome 3.6
embryonal carcinoma 3.6
NS3 3.5
stromal tumors 3.5
azoospermia 3.5
cutaneous melanoma 3.4
retinoblastoma 3.4
pituitary adenoma 3.4
lymphoblastic leukemia 3.4
obsessive-compulsive disorder 3.3
multiple myeloma 3.3
choriocarcinoma 3.3
scrotum 3.3
CEM 3.2
hepatic encephalopathy 3.2
Still 3.2
Kaposi's sarcoma 3.2
non-small cell lung cancer 3.1
genetic disorder 3.1
neurological disease 3.1
MAS 3.1
Cushing's syndrome 3.1
HCG 3.0
respiratory failure 3.0
neoplastic transformation 3.0
renal cancer 3.0
vaccinia 2.9
male infertility 2.9
chronic lymphocytic leukemia 2.9
sleep disturbances 2.8
MCF 2.8
mimicry 2.8
muscular dystrophy 2.8
uremia 2.7
lung carcinoma 2.7
lung cancer 2.7
carcinoma in situ 2.7
aggressiveness 2.7
IVF 2.7
skin cancer 2.7
carcinogenesis 2.6
autism 2.6
mammary tumor 2.6
PDB 2.6
basal cell carcinoma 2.6
pancreatic cancer 2.5
neuroblastoma 2.5
Legionella 2.5
dementia 2.5
Pancreas 2.5
macular degeneration 2.5
chronic lymphocytic leukemia 2.5
Schistosoma mansoni 2.5
Pancreas 2.5
solid tumor 2.4
Melanoma 2.4
metastatic breast cancer 2.4
tumor progression 2.3
hematologic malignancies 2.3
liver fibrosis 2.3
WT1 2.3
myocarditis 2.2
periodontal disease 2.2
scoliosis 2.2
ulcerative colitis 2.2
glioblastoma multiforme 2.1
ICD 2.1
dilated cardiomyopathy 2.1
adenocarcinoma 2.0
breast cancer 2.0
lymphoma 1.9
colorectal cancer 1.9
squamous cell carcinoma 1.9
SCID 1.9
epithelial ovarian cancer 1.8
subarachnoid hemorrhage 1.8
Epstein 1.7
hypertension 1.7
virus infection 1.7
Brown 1.7
tumor 1.7
periodontitis 1.7
cystic fibrosis 1.7
SDS 1.7
ATM 1.6
cancer 1.6
Autism 1.5
dermatitis 1.5
Alzheimer's disease 1.5
dyslipidemia 1.5
herpes simplex 1.5
bipolar disorder 1.5
prostate cancer 1.4
glioma 1.4
pancreatitis 1.3
dysplasia 1.3
worms 1.2
carcinoma 1.2
vascular disease 1.2
sepsis 1.2
acute myeloid leukemia 1.2
hepatocellular carcinoma 1.2
gastric cancer 1.1
cognitive impairment 1.1
chronic disease 1.1
glioblastoma 1.1
GSH 1.1
colitis 1.0
tumor growth 1.0
sepsis 1.0
primary tumor 1.0
type 1 diabetes 0.9
cardiomyopathy 0.9
cirrhosis 0.9
adenoma 0.9
Crohn's disease 0.9
confusion 0.9
glaucoma 0.8
melanoma 0.8
inflammatory bowel disease 0.8
leukemia 0.8
SEM 0.8
immunodeficiency 0.7
dehydration 0.7
proteinuria 0.7
heart failure 0.7
metastases 0.6
plaque 0.6
suicide 0.5
ovarian cancer 0.5
cytomegalovirus 0.5
colon cancer 0.5
hyperglycemia 0.4
schizophrenia 0.4
hepatitis 0.4
Hodgkin's disease 0.4
myocardial ischemia 0.3
cardiovascular disease 0.3
hepatitis C 0.2
Infection 0.1
hepatitis B 0.1
malaria -0.2
cold -0.2
Mycobacterium -0.4
obesity -0.6
epilepsy -0.7
myocardial infarction -0.7
arthritis -0.8
tuberculosis -0.9
infectious diseases -1.1
depression -1.1
diabetes -1.8
stroke -1.9
HIV -2.1
Symptom
ataxic gait 6.2
ataxia 3.6
starvation 3.5
cerebellar ataxia 3.5
hypotonia 2.8
dystonia 2.2
seizures 2.2
tremor 2.1
functional recovery 1.6
collapse 1.5
acidity 1.4
weakness 1.1
overweight 0.6
Drug
Parkin 9.8
Parkin 9.8
Jujube 9.1
Pirarubicin 8.8
Bortezomib 6.7
TAK 6.3
Dasatinib 6.0
GEO 5.7
CIA 5.7
AMC 5.1
CoCl2 5.0
CoCl2 5.0
Arsenic trioxide 5.0
Ginseng 4.6
lysine 4.5
CPT-11 4.4
uPA 4.2
Alanine 3.8
Heme 3.7
Taxol 3.6
Retinoic acid 3.6
Kenyan 3.5
Glutathione 2.9
ICI 2.9
nitroglycerin 2.2
caffeine 0.9
NADH 0.9
IL-2 0.4
CSF 0.4
Dermatol -2.7
Enzyme
ubiquitin-protein ligase 15.3
ubiquityl-calmodulin synthetase 13.9
5,10-methenyltetrahydrofolate synthetase 10.8
3-hydroxybutyryl-CoA dehydrogenase 9.6
aminopeptidase I 9.4
arginyl-tRNA synthetase 9.2
galactinol synthase 8.8
isopeptidase 8.7
3C protease 8.3
proteasome 8.0
type 1 protein phosphatase 7.9
S-adenosyl-L-homocysteine hydrolase 7.2
separase 6.9
m-calpain 6.6
IscS 6.5
trehalase 6.5
chorismate mutase 6.5
diacylglycerol kinase 6.3
p80 6.2
cysteine synthase 6.0
3-hydroxyacyl-CoA dehydrogenase 5.9
fatty acid desaturase 5.8
E-2 5.8
glycerol kinase 5.8
leucine aminopeptidase 5.6
TSP-1 5.6
APC 5.5
cystathionine beta-synthase 5.4
IKK 5.3
ECH 5.2
NADH dehydrogenase 5.2
3-hydroxy-3-methylglutaryl-CoA reductase 5.2
alpha-ketoglutarate dehydrogenase 5.0
transketolase 4.9
DNA ligase 4.9
DNA ligase 4.9
TOR 4.8
farnesyltransferase 4.7
protein phosphatase 2A 4.7
PNGase F 4.7
polo-like kinase 1 4.7
granzyme B 4.6
cdc2 4.6
enolase 4.4
glutaminase 4.4
cathepsin L 4.3
chaperonin 4.2
complex I 4.2
thioredoxin reductase 4.0
hexokinase 3.9
lysozyme 3.9
RNA polymerase 3.9
MDP 3.9
histone acetyltransferase 3.9
phosphoinositide 3-kinase 3.8
diaphorase 3.8
isocitrate dehydrogenase 3.7
protein kinase 3.7
transcriptase 3.7
ornithine decarboxylase 3.6
furin 3.6
ricin 3.6
glutathione S-transferase 3.6
beta-glucosidase 3.6
ribonuclease 3.6
ribonuclease 3.6
isocitrate dehydrogenase 3.5
aldolase 3.5
arginase 3.4
CaMKII 3.3
proteinase K 3.3
cathepsin D 3.3
heme oxygenase 3.2
MMP 3.2
calcineurin 3.2
RNase 3.1
PARP 3.1
topoisomerase 3.0
DNA methyltransferase 3.0
caspase-3 3.0
ATPase 2.9
luciferase 2.9
NQO1 2.7
caspase-1 2.7
ERK 2.5
caspase-8 2.5
prostate-specific antigen 2.5
ATP synthase 2.5
beta-galactosidase 2.4
carbonic anhydrase 2.4
caspase-9 2.4
DNase 2.4
beta-glucuronidase 2.4
glucose-6-phosphate dehydrogenase 2.4
RNase 2.3
lipoxygenase 2.2
cytochrome oxidase 2.2
topoisomerase 2.1
phospholipase C 2.1
alcohol dehydrogenase 2.1
mitogen-activated protein kinase 2.1
CD10 2.0
chymotrypsin 1.9
protein kinase C 1.7
AMPK 1.7
acid phosphatase 1.6
AMP-activated protein kinase 1.6
trypsin 1.5
phospholipase A2 1.5
focal adhesion kinase 1.4
NO synthase 1.3
reverse transcriptase 1.3
DNA polymerase 1.2
endonuclease 1.1
lipase 1.1
phosphodiesterase 1.1
superoxide dismutase 1.0
lactate dehydrogenase 0.4
renin 0.2
ACS -1.0
Compound
Methyl caffeate 12.1
3-fluoropyridine 10.6
RUB 10.3
1,4-cyclohexanedione 9.7
Ubiquitin 9.3
Perillyl alcohol 9.2
Perillyl alcohol 9.2
Vinclozolin 9.1
PYR 8.8
Cbl 8.6
Embelin 8.4
Arabinogalactan 7.7
DGE 7.6
DGE 7.6
DGE 7.6
G 1 7.3
SSH 7.2
PPi 6.6
AICAR 6.6
CHIP 6.6
5-Azacytidine 6.5
DBT 6.4
Cortisone 6.4
AAA 6.3
AF-2 6.2
APH 6.1
DMPP 6.1
Glycogen synthase 6.1
Isoform 6.0
Arsenite 6.0
methanethiol 5.8
Uracil 5.7
AICAR 5.7
DEP 5.7
3-methylhistidine 5.7
Cycloheximide 5.6
MAD 5.6
Brefeldin A 5.6
Brefeldin A 5.6
adenylate 5.5
malononitrile 5.4
E-64 5.4
DEP 5.3
Artemisinin 5.3
SN-38 5.2
POP 5.0
isopentenyl diphosphate 4.9
40S 4.8
Guanine 4.8
lysine 4.7
CCP 4.6
Methamphetamine 4.6
Casein 4.5
myricetin 4.5
aldosterone 4.5
C2H2 4.5
CPT-11 4.4
ATF 4.4
DTT 4.3
DTT 4.2
DOC 4.2
BCNU 4.1
Vasopressin 4.1
Leucine 4.1
DPP 4.0
IAA 4.0
Arachidonic acid 4.0
DSS 4.0
ATP 4.0
Alanine 3.9
TNM 3.9
MMC 3.9
retinoic acid 3.9
IAA 3.8
GSSG 3.8
cysteine 3.8
pyrimidine 3.8
nicotinic acid 3.7
nicotinic acid 3.7
nicotinic acid 3.7
Quercetin 3.6
Rapamycin 3.6
succinic acid 3.5
Heme 3.5
PDB 3.4
DEAE 3.4
Ile 3.3
aniline 3.3
Gly 3.2
nicotinic acid 3.2
threonine 3.2
ABA 3.2
EMS 3.2
L-DOPA 3.1
serine 3.1
GAL 3.1
aldehyde 3.1
molybdenum 3.1
NAD 3.0
leucine 3.0
isoleucine 3.0
isoleucine 2.9
MPTP 2.9
AMP 2.9
hydroxylamine 2.9
HCO 2.9
arginine 2.9
ABA 2.9
methionine 2.9
APAP 2.9
pyrrolidine 2.9
cyanide 2.8
hydrazine 2.8
Cortisol 2.8
zinc 2.8
hydroxylamine 2.8
pyrrolidine 2.8
tyrosine 2.8
FK506 2.8
butyric acid 2.8
NH2 2.8
ubiquinone 2.7
aldehyde 2.7
butyric acid 2.7
COS 2.7
ICI 2.6
NAD 2.6
Melatonin 2.6
butyric acid 2.5
alanine 2.5
salt 2.5
quinoline 2.5
quinoline 2.5
benzoic acid 2.4
proline 2.3
MDA 2.3
Phytol 2.3
Phytol 2.3
adenosylmethionine 2.2
alcohol dehydrogenase 2.2
Phe 2.2
Asp 2.2
Dopamine 2.2
Collagen 2.1
GTP 2.0
His 2.0
Cholesterol 2.0
retinol 2.0
H2O2 2.0
THP 1.9
THP 1.9
sodium 1.9
salicylic acid 1.8
GDP 1.8
cAMP 1.8
DNA 1.8
uridine 1.6
SDS 1.6
ethyl acetate 1.5
GSH 1.5
GSH 1.5
Mg2+ 1.5
valine 1.4
hexane 1.4
ammonium 1.3
glutamic acid 1.3
cadmium 1.2
tryptophan 1.2
tryptophan 1.2
nitrogen 1.2
tryptophan 1.1
boron 1.1
sulfate 1.1
nitric oxide 1.0
TOF 1.0
tryptophan 0.9
urea 0.9
bromide 0.9
caffeine 0.9
NADH 0.9
glutamate 0.7
NADPH 0.7
NADPH 0.7
glutamine 0.6
calcium 0.5
silver 0.4
titanium 0.4
TNF 0.4
nickel 0.4
5-HT 0.3
MTT 0.3
glucose 0.3
Pac 0.2
GABA 0.2
manganese 0.2
GABA 0.2
galactose 0.1
Dec 0.0
glycerol -0.0
iron -0.2
phosphorus -0.2
iodine -0.3
creatinine -0.6
methanol -0.6
ethanol -0.8
ACS -1.0
ACS -1.0
water -1.1
hydrogen -1.4
Cardiol -1.6
oxygen -1.6
phosphate -2.1
BMC -2.2
Clin -2.5