Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.3.2.19 (ubiquitin-protein ligase)
 799 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ubiquitin-protein ligase 547
ubiquitin 433
proteasome 186
Mol 93
ubiquitin-conjugating enzyme 63
p53 59
Sep 59
Ubiquitin 55
ATP 52
ubiquitin ligase 51
Parkin 43
parkin 36
Nedd4-2 28
endoplasmic reticulum 27
E6-AP 25
SCF 24
ENaC 24
proteasome inhibitor 23
cyclin 22
RSP5 22
E3 ubiquitin ligase 21
UBE3A 20
E6AP 18
UBC4 18
E2 ubiquitin-conjugating enzyme 18
APC 16
tRNA 16
Skp1 13
ATPase 12
E6 protein 12
UbcH7 11
cytokine 11
alpha-synuclein 11
polypeptide 11
HERC1 11
PINK1 11
F-box protein 11
NMR 10
collecting duct 10
RNA polymerase II 10
UBA1 10
ubiquitin carrier protein 10
RING-H2 10
interacting protein 10
Mdm2 9
interferon 9
lysozyme 8
PARK2 8
ubiquitin-like protein 8
cullin 8
UBE1 8
PTEN 8
novel gene 8
sodium channel 8
histone 8
proline-rich 8
septin 8
histone H2B 7
caspase-3 7
AMP 7
calmodulin 7
MDM2 7
p27 7
UBA6 7
epidermal growth factor receptor 7
membrane protein 7
UBE1L 7
RING finger protein 6
cyclin-dependent kinase 6
anaphase-promoting complex/cyclosome 6
Itch 6
Met 6
AAA 6
calpain 6
PARKIN 6
Proteasome 6
securin 6
tumor necrosis factor 6
transcriptional activator 6
all-trans 6
NEDD8 6
Cyclin 6
cage 5
Ubiquitin-protein ligase 5
14-3-3 5
amino acid permease 5
serine/threonine kinase 5
tyrosine kinase 5
UBR1 5
FAT10 5
SFT 5
phosphatase 5
WWP2 5
E2-F1 5
p62 5
Ankyrin 5
H2A 5
zinc finger 5
estrogen receptor 5
atrogin-1 5
finger protein 5
histone H3 5
Skp2 5
nuclear protein 5
alpha, beta 5
interleukin-6 5
GTPase 5
UbcH8 5
unknown function 5
threonine 4
ubiquitin-specific protease 4
SDS 4
NEDD4 4
adaptor protein 4
SKP2 4
ERK 4
inhibitor of apoptosis 4
PDB 4
H2B 4
vimentin 4
IkappaBalpha 4
small GTPase 4
IkappaB kinase 4
CBL 4
ubiquitin-activating enzyme E1 4
UBC9 4
HACE1 4
XIAP 4
CDC20 4
spermatozoa 4
synphilin-1 4
cytochrome c 4
proliferating cell nuclear antigen 4
p27Kip1 4
membrane-bound 4
cyclin D1 4
GST 4
ALA 4
UBP43 4
histone H2A 4
p38 4
E1B 4
Rho 4
UFD2 4
promyelocytic leukemia 4
protein phosphatase 4
deubiquitinating enzyme 4
NAD 4
USP18 3
Cdc48 3
insulin 3
Fas 3
ARI 3
CCR4-NOT 3
gamma-tubulin 3
HUWE1 3
FBXO6 3
olfactory 3
vasopressin 3
telomeric 3
GTP 3
nuclear receptor 3
TNM 3
glutathione S-transferase 3
tumour suppressor 3
HEK 3
cytochrome P450 3
p97 3
hormone receptor 3
prion 3
E3 protein 3
progesterone receptor 3
hepatocyte growth factor 3
SKP1 3
Mule 3
cyclin F 3
CHIP 3
chimeric protein 3
c-Jun 3
lipopolysaccharide 3
LPS 3
catenin 3
erythropoietin 3
cIAP2 3
p73 3
LC3 3
HSP70 3
UBC 3
diubiquitin 3
SOD 3
Ubc13 3
TLR4 3
superoxide dismutase 3
ARF 3
p65 3
H2AX 3
albumin 3
Bcl-2 3
gene 4 3
receptor tyrosine kinase 3
Hdm2 3
dimeric 3
transcriptional regulator 3
chloride channel 3
CDC16 3
erythroid 3
cyclin B1 3
ISG15 3
COP9 3
cyclin-dependent kinase inhibitor 3
glycoprotein 3
tumor suppressor protein 3
IFN 3
p21 3
CCNF 3
proto-oncogene 3
APC11 3
c-fms 2
D. melanogaster 2
MAPK 2
ornithine decarboxylase 2
vascular endothelial growth factor 2
MHC class I 2
RING1 2
beta-catenin 2
glial fibrillary acidic protein 2
NEDD4L 2
Rbx1 2
p11 2
ARIH1 2
protein C 2
myosin 2
LRRK2 2
STAT3 2
Ubiquitin-conjugating enzyme 2
dystrophin 2
DJ-1 2
UCHL1 2
cbl-b 2
TRIM 2
ubiquitin conjugating enzyme 2
RanBP2 2
matrix protein 2
phosphoinositide 3-kinase 2
Glycogen synthase 2
SC35 2
elongin C 2
BiP 2
UBE2L3 2
RNF40 2
VHL 2
Pop1 2
pol 2
E2 protein 2
SUMO 2
p105 2
HDM2 2
SMAX2 2
N-myc 2
dynamin 2
UBE2D1 2
CK2 2
Praja-1 2
extracellular signal regulated kinase 2
dynamin-related protein 1 2
SMAD4 2
GABA(A) receptor 2
syntaxin 2
core protein 2
MyD88 2
AGP1 2
PWI 2
Doc1 2
AKT 2
PML 2
TRIP12 2
JAK2 2
peptidase 2
gp78 2
amyloid precursor protein 2
FBG1 2
VCP 2
Uba5 2
ATG7 2
TRIM32 2
NADH dehydrogenase 2
EDD 2
CUL1 2
transmembrane protein 2
FBXW7 2
hexokinase 2
MAP1LC3B 2
peroxisome proliferator-activated receptor 2
JNK 2
RING-IBR 2
pRb 2
potential tumor suppressor 2
adapter protein 2
c-myc 2
Ki-67 2
TAK 2
HLA-F 2
BRUCE 2
UBR5 2
p14 2
NEDD4 protein 2
EST) 2
MMP-9 2
E-cadherin 2
arginyl-tRNA-protein transferase 2
CDC23 2
UbcH6 2
X-linked inhibitor of apoptosis protein 2
hedgehog 2
casein 2
leucine zipper 2
heat shock protein 2
AICAR 2
heat shock protein 90 2
cyclin E 2
autoantigen 2
Pin1 2
synuclein 2
LC3B 2
like kinase 2
SUMO2 2
TRIM21 2
UFM1 2
LAP 2
arginyl-tRNA synthetase 2
UBA3 2
mineralocorticoid receptor 2
SPINK2 2
ankyrin 2
TNF receptor-associated factor 3 2
MyoD 2
ubiquitin C 2
MMS2 2
USE1 2
NLRP2 2
adenomatous polyposis coli 2
RNF168 2
RNF43 2
CYLD 2
trehalase 2
p45 2
DIAP1 2
ubiquitin-fold modifier 1 2
STAT 2
EF-Tu 2
ubiquitin-protein isopeptide ligase 2
CDC26 2
TSG101 2
androgen receptor 2
nuclear hormone receptor 2
Hsp40 2
collagen 2
MYC 2
granzyme B 2
sugar transporter 2
RNase A 2
PI3K 2
Yes 2
RBX1 2
TRAF6 2
pVHL 2
53BP1 2
PARP 2
MYCBP2 2
AP-2 2
eukaryotic translation initiation factor 2
RNF186 2
GSH 2
methyltransferase 2
p50 2
ubiquitin-conjugating enzyme E2 2
TNF 2
Ubiquitin-activating enzyme 2
GTPase-activating protein 2
UBA2 2
MYB 2
UCH-L1 2
Gab2 2
SOD1 2
ClC-5 2
ribosomal protein L11 2
enolase 2
fused 2
TDP-43 2
caspase-9 2
TLR9 2
DNMT3A 2
endoprotease 2
muscle protein 2
scribble 2
UBE2M 2
cadherin 2
SMAD3 2
PKC zeta 2
ERK1 2
cyclin A 2
SGK1 2
serine/threonine protein kinase 2
mast cell 2
G protein-coupled receptor 2
DGK 1
RuvB-like 2 1
Elongin B 1
tropomodulin 1
fetal kidney 1
transketolase 1
sky 1
leucine-rich repeat kinase 2 1
ribosomal protein S6 kinase 1 1
RNF26 1
leptin 1
PKA 1
PSMC4 1
1C5 1
S10 1
Multidrug resistance protein 3 1
MMR 1
sonic hedgehog 1
aminopeptidase 1
regucalcin 1
MIB 1
HBZ protein 1
RECK 1
p32) 1
NYGGF4 1
helicase II 1
human leukocyte antigen 1
Cu/Zn superoxide dismutase 1
splicing factor 1
p32 1
DNA repair enzyme 1
p27(KIP1) 1
alcohol dehydrogenase 1
MTHFS 1
NURR1 1
galectin-3 1
cyclin-dependent kinase inhibitor p27 1
US2 1
ERN1 1
Zap 1
NEDD4-2 1
MRE11 1
RNF41 1
single-stranded DNA-binding protein 1
pepsinogen 1
SHARPIN 1
Mal 1
PGC 1
phospholipase A2 1
p12 1
Ubiquitin carboxyl-terminal hydrolase 1
PICT-1 1
RBBP8 1
ribosomal protein 1
HNA 1
occludin 1
iron regulatory protein 2 1
TRAIL 1
prostate-specific antigen 1
MDC1 1
KEN 1
PABP 1
AHNAK protein 1
RING1A 1
HRD1 1
spliceosomal protein 1
seven in absentia homolog 2 1
WD-repeat protein 1
sperm surface protein 1
USP22 1
LNX 1
LDOC1 1
COL3A1 1
ICD 1
HDAC1 1
PCTK1 1
ubiquitin-like modifier activating enzyme 3 1
UT-A2 1
calcium-activated neutral protease 1
apoE 1
tumor necrosis factor alpha 1
sideroflexin 2 1
SCD1 1
sentrin 1
trypsin inhibitor 1
rhodopsin 1
CARD9 1
PSAP 1
EGFR 1
RNF139 1
PSMA1 1
UHRF2 1
hnRNP D 1
RAD52 1
interferon-beta 1
p90 1
lysosome-associated membrane protein-2 1
quinone oxidoreductase 1
HA1 1
KAI1 1
RIG-I 1
elongation factor 2 1
FANCJ 1
tensin 1
PMEPA1 1
UBE2G2 1
Ufc1 1
par-4 1
AKAP3 1
spleen tyrosine kinase 1
heterogeneous nuclear ribonucleoprotein K 1
metallothionein 1
metastasis suppressor 1
DSS 1
RBCC 1
Ring finger protein 1 1
DNAJB6 1
lipoxygenase 1
ALS 1
SHP 1
HSF2 1
ferredoxin 1
L12 1
ubiquitin-protein isopeptide ligase (E3) 1
RasGAP 1
TRF1 1
TNF-alpha 1
vascular endothelial growth factor A 1
MDA5 1
retinoic acid receptor alpha 1
Janus kinase 1
UBB 1
ubiquitin fusion protein 1
barttin 1
glutaminase 1
TXNIP 1
NEDD4-1 1
c-MYC 1
lectin 1
FBS 1
NQO1 1
ESI 1
glycerol kinase 1
thyroid hormone 1
PDE2 1
SALL4B 1
Id4 1
ZFX 1
CIS 1
YWHAZ 1
outer mitochondrial membrane 1
UBE2C 1
NPH3 1
plasminogen activator inhibitor-1 1
axonal 1
cystic fibrosis transmembrane conductance regulator 1
NEP 1
peptidoglycan recognition protein 1
cell cycle-related protein 1
DEAD 1
chromodomain helicase DNA binding protein 2 1
DRP1 1
SRC-1 1
ELK1 1
Smad1 1
CaMKII 1
EPA 1
DPP 1
CLCN5 1
poly(A)-binding protein 1
UBC13 1
cysteine protease 1
CCND3 1
pyrophosphatase 1
zinc finger motif 1
XPB 1
MAPK1 1
AF-1 1
DICER1 1
caveolin-3 1
processed form 1
NOT4 1
retinal protein 1
CHD2 1
lactate dehydrogenase 1
aryl hydrocarbon receptor 1
expressed in testis 1
SRP9 1
hepatocyte growth factor-regulated tyrosine kinase substrate 1
CRV 1
MRI 1
POSH 1
SUG1 1
arrestin domain containing 4 1
TIP60 1
HERC2 1
transferrin 1
AIP2 1
ubiquitin carboxyl-terminal hydrolase 1
metalloproteinase 1
rpl11 1
VPS13D 1
Ubiquitin-like modifier activating enzyme 1 1
mucin 1
WBP-1 1
NHE1 1
thioredoxin interacting protein 1
motor protein 1
C2H2 1
UBC2 1
MDP 1
APH 1
ARNT 1
cAMP-dependent protein kinase 1
poly(ADP-ribose) polymerase 1
SPT6 1
CCL7 1
BMP9 1
MCP-3 1
plasminogen 1
ABO 1
synaptojanin 1
FBL7 1
serum albumin 1
GTP-binding protein 1
Rpn13 1
interferon regulatory factor 3 1
RNA-binding protein 1
geminin 1
CD105 1
P29 1
MEX67 1
farnesyl diphosphate synthase 1
TOP2A 1
NPR1 1
ATG16L1 1
reductase 1
Occludin 1
NBS1 1
DNA gyrase 1
TRIM24 1
Nrf2 1
phosphodiesterase 1
LIG4 1
epididymal 1
DNA polymerase alpha 1
WW domain binding protein 2 1
ZNF645 1
CASK 1
bcl-2 1
Set1 1
vitronectin 1
manganese superoxide dismutase 1
HMG-CoA reductase 1
p53-binding protein 1
Kir2.1 1
DDB1 1
cytochrome 1
glucocerebrosidase 1
CGR19 1
ubiquitin-conjugating enzyme 9 1
Derlin-2 1
IL23R 1
Cap43 1
Nav1.5 1
hsp70 1
NPI-1 1
MnSOD 1
lysosomal protein 1
calcineurin 1
Mad2 1
spinocerebellar ataxia type 2 1
PGK1 1
galanin 1
CD4 1
Voltage-gated sodium channel 1
EZH2 1
FHIT 1
efp 1
Epidermal growth factor 1
CtIP 1
EGF 1
SLC25A5 1
MIM 1
CMS 1
histone deacetylase 6 1
E6TP1 1
RNF4 1
TCR zeta chain 1
B protein 1
Pseudomonas 1
SAE1 1
interferon-gamma 1
serum protein 1
FBXW8 1
phosphorylating 1
PTPRJ 1
SLUG 1
ATF6 1
PRC1 1
STAT5 1
FKBP12 1
thymopoietin 1
TPRD 1
RTF1 1
Creatine kinase 1
O6-methylguanine-DNA methyltransferase 1
homeodomain transcription factor 1
p15 1
flavoprotein 1
TRAF-interacting protein 1
ATF 1
protein disulfide isomerase 1
VP2 1
ribosomal S6 kinase 1
RCC1-like 1
RAD50 1
A-T 1
ataxia telangiectasia mutated 1
Hexokinase 1
SHFM3 1
PERK 1
thymus 1
aldolase B 1
cyclin D3 1
+Ca 1
MICB 1
p53 binding protein 1
Gen 1
A-I 1
chymotrypsin 1
TOM70 1
HDEL 1
FKBP51 1
TPI1 1
alpha-tubulin 1
TINO 1
apolipoprotein B 1
RNF20 1
dishevelled 1
RLR 1
S100A8 1
interleukin-4 1
FAT1 1
SMA 1
ataxin-3 1
Axin 1
DNA-dependent protein kinase 1
TMX1 1
MFF 1
IVF 1
Histone deacetylase 1
HSD1 1
KIAA0675 1
Toll/interleukin-1 receptor 1
PSMD1 1
HSF1 1
IKK 1
Fe65 1
GABA 1
mitogen-activated protein 1
ataxin-1 1
San 1
HA2 1
P450 1
promyelocytic leukemia protein 1
c-Myc 1
vinculin 1
mdm2 1
HAND1 1
truncated variant 1
NAIP 1
GEF 1
HDAC4 1
DRIP1 1
UBE2H 1
DNA methyltransferase 1
DZIP3 1
BI-1 1
Transporter 1
dentatorubral-pallidoluysian atrophy 1
MGD1 1
C-terminal peptide 1
voltage-gated sodium channel 1
GDF15 1
FBXO17 1
APC10 1
Tom40 1
vascular endothelium 1
FKBP3 1
HIF-1beta 1
NDUFS2 1
aromatase 1
CRABP 1
Chk2 1
CUL4B 1
lipase 1
HSD17B10 1
ASK1 1
HMGCS1 1
hect domain and RLD 5 1
TRAIP 1
RNF144A 1
mitofusin 2 1
optineurin 1
sentrin-specific protease 1
VCY2 1
ACAT2 1
extracellular signal-regulated kinase 1
Atrogin-1 1
HMG-CoA synthase 1
APC8 1
FKBP52 1
PHP 1
RACE 1
Rpn10 1
PSP94 1
beta-spectrin 1
granulocyte colony-stimulating factor receptor 1
antizyme 1
MuRF1 1
ryanodine receptor 1
CPR 1
CHFR 1
Dnmt3b 1
S-adenosyl-L-homocysteine hydrolase 1
neurotrophin 1
UQCRC1 1
DNA binding protein 1
ARAF1 1
Ro52 1
DNMT3B 1
DRIP2 1
WW domain-containing 1
NADPH 1
separase 1
CLL 1
RIP1 1
myostatin 1
dynactin 1
FGFR1 1
organic anion transporter 1
AIF4 1
AMP-activated protein kinase 1
p38 mitogen-activated protein kinase 1
CCL2 1
NADH 1
cyclin dependent kinase 1
Rab7 1
serotonin transporter 1
casein kinase 1
retinoic acid receptor 1
FBL3 1
formin-like 1 1
SRP14 1
PHP2 1
BMP10 1
78 kDa 1
TM3 1
NOTCH3 1
activating transcription factor 6 1
CIC 1
GAL1 1
FBG3 1
RBP1 1
p16 1
troponin T 1
KIP1 1
TFE3 1
cell adhesion molecule 1
envelope glycoprotein 1
UBC7 1
INK4a 1
FLRF 1
Ubc6p 1
P19 1
UBE2G1 1
EGF receptor 1
caspase-8 1
SRP54 1
KIAA0554 1
K12 1
type I interferon 1
cIAP1 1
SLI 1
DBT 1
Smac 1
heterogeneous nuclear ribonucleoprotein A3 1
TRIM25 1
MSV 1
Bid 1
aldolase A 1
Pellino 1
protease inhibitor 1
linker histone 1
RP4 1
MET 1
ephrin-B1 1
cathepsin D 1
TOF 1
PDZRN3 1
RNF216 1
THP 1
4EBP1 1
MPN 1
granzyme A 1
sigma 3 protein 1
carbonic anhydrase 1
Sharpin 1
ANOVA 1
UBR4 1
CA1 1
activating transcription factor 3 1
C1QL4 1
ribonucleoprotein 1
coactivator for steroid receptors 1
RPS4X 1
HER2 1
CCAAT/enhancer-binding protein homologous protein 1
RIG1 1
anion transporter 1
MLR 1
cathepsin L 1
HGF 1
BRIP1 1
MAS 1
X-linked 1
major histocompatibility complex class I 1
nitric oxide synthase 1
ubiquitin C-terminal hydrolase 1
YWHAE 1
FK506 1
HIS3 1
brca2 1
RP11 1
AHNAK 1
cdk2 1
CSF 1
vascular endothelial growth factor receptor 2 1
GAT1 1
protein-tyrosine kinase 1
ANKRD13D 1
TM1 1
C protein 1
MMP-2 1
ribonuclease A 1
IRAK1 1
synexin 1
TOP1 protein 1
Sp1 1
ADP-ribosylation factor domain protein 1 1
RPN2 1
seminal plasma protein 1
MAPK3 1
GRAIL 1
GAP43 1
PKR 1
testis-specific 1
protein phosphatase 2C 1
Sp1 protein 1
prolyl isomerase 1
c-fos 1
SALL3 1
FGF8 1
SALL1 1
FISH 1
STAM-1 1
tropomyosin 1
E2F1 1
TRIF 1
H-ras 1
ANKRD13B 1
protein kinase B 1
ORP150 1
ras 1
calcium-independent phospholipase A2 1
beta-glucuronidase 1
short form 1
Phosphatase and tensin homolog 1
phosphatase and tensin homolog 1
zinc transporter 1
CIN85 1
CUL3 1
CSE1 1
EF1B 1
platelet-derived growth factor 1
cullin 3 1
NACP 1
cereblon 1
DIABLO 1
PP1 1
myeloid zinc finger 1 1
TOP1 1
IL-6 1
INSIG1 1
aryl hydrocarbon receptor nuclear translocator 1
OPA1 1
insulin induced gene 1 1
MMP 1
Apaf-1 1
NADH-ubiquinone oxidoreductase 1
RhoA 1
REDD1 1
TLR2 1
topoisomerase I 1
AQP2 1
mutant p53 1
TLR7 1
lymphoid 1
HNRNPK 1
TFIIH 1
R12 1
endonuclease 1
GPX7 1
HSPD1 1
APP-BP1 1
c-Met 1
N-glycanase 1
BRAF 1
Mex67 1
GORAB 1
p17 1
Boc 1
PMEPA1 protein 1
Brca1 1
ring finger protein 1
cysteine desulfurase 1
factor H 1
serine/threonine-protein kinase 1
cytoplasmic protein 1
USP8 1
ECT2 1
TOPORS 1
LRPPRC 1
FBA 1
calpastatin 1
p80 1
cytokine receptor 1
NFE2L2 1
transcription repressor 1
crystallin 1
acrosin inhibitor 1
IAP 1
CIP1/WAF1 1
UBE3A protein 1
ADP-ribosylation factor 1
CRBN 1
glycine-rich protein 1
EEF2 1
AAG 1
SRC 1
HSJ1a 1
annexin V 1
SWM1 1
enigma 1
chaperonin 1
HBZ 1
putative E3 ubiquitin ligase 1
RING-finger protein 1
IL-2 1
ERBB2 1
Cytokine 1
CPSF7 1
DNMT1 1
NTKL 1
RAI3 1
ficolin 1
HSP60 1
IMPDH2 1
Derlin-1 1
p55 1
titin 1
MAGE-D 1
TRIM36 1
adipose triglyceride lipase 1
alpha-ketoglutarate dehydrogenase 1
HOIL-1 1
Dictyostelium 1
RFPL4 1
calreticulin 1
PKS 1
bFGF 1
HIF-1alpha 1
cathepsin 1
Fas ligand 1
UBE2O 1
cytochrome c oxidase 1
renin 1
tau protein 1
VIM 1
MuRF 1
FBXO27 1
MDP1 1
A-kinase anchoring protein 1
KCa3.1 1
PC-3 1
GABRB3 1
Hsp60 1
SP1 1
TOR 1
HELZ 1
KIT 1
zinc metallopeptidase 1
AP-1 1
LBP-1 1
Grp170 1
LMO2 1
transformation/transcription domain-associated protein 1
metallopeptidase 1
DnaJ/Hsp40 chaperone 1
kelch 1
PGP 9.5 1
MCP-1 1
Chk1 1
helicase 1
histone acetyltransferase 1
CD11b 1
Cellular tumor antigen p53 1
inward rectifier 1
ERK2 1
Layilin 1
IgE 1
PTPRG 1
GRIP2 1
protein-tyrosine phosphatase 1
40S ribosomal protein S3a 1
GSPT1 1
histone H1 1
PARP-1 1
C/EBP homologous protein 1
pericentrin 1
transgelin 1
PARP1 1
Id3 1
cytochrome P450 2E1 1
SUMO1 1
PDS5 1
PSMD7 1
GDP 1
insulin-like growth factor 1
Vaccinia-related kinase 3 1
ICAM-3 1
ubiquitin protease 1
ARD1 1
ARRDC4 1
coilin 1
nucleolar protein 1
XRN2 1
Hsp70-interacting protein 1
APC1 1
5'-3' exoribonuclease 2 1
methylguanine-DNA methyltransferase 1
kinase-like protein 1
Sec62 1
Id1 1
thioredoxin reductase 1
MAP kinase 1
BRCA1 1
CRL4 1
heme oxygenase-1 1
RP-A 1
ubiquitin-like protein Nedd8 1
p63 1
HIRIP3 1
mitochondrial ATPase 1
CDH1 1
partial protein 1
transcriptional factor 1
CIA 1
glucose-6-phosphate dehydrogenase 1
BP1 1
Dnmt1 1
platelet-derived growth factor receptor 1
polo-like kinase 1 1
TRIP 1
ACS 1
Dnmt3a 1
LAT 1
VHL protein 1
SAE2 1
CKB 1
FAP48 1
RNF206 1
HOXA1 1
Cullin-1 1
nuclear factor of activated T-cells 1
Poly 1
AP180 1
ATXN2 1
guanine nucleotide binding protein 1
Aurora-A 1
AE4 1
BMP2 1
poly (ADP-ribose) polymerase 1
X-chromosome 1
survivin 1
Epidermal growth factor receptor 1
TRRAP 1
protein phosphatase 2 1
phosphoprotein 1
BIRC5 1
USP10 1
RNF128 1
TOMM22 1
ubiquitin thiolesterase 1
isocitrate dehydrogenase 1
fur 1
hemoglobin 1
PPP2R1A 1
CUL4 1
PHR1 1
DAG 1
KCNQ1 1
zinc finger protein 1
JAB1 1
signal recognition particle 1
pendrin 1
CDC27 1
KDELR3 1
CDK4 1
EIF-5A 1
PC3 1
thyroid hormone receptor 1
MAD 1
p34 1
alpha-actinin 1
Cyclin-dependent kinase 1
ubiquinone 1
squalene synthase 1
L11 1
agouti 1
BMF 1
ART 1
GW182 1
lactotransferrin 1
nucleolar and coiled-body phosphoprotein 1 1
Notch3 1
Pol 1
PAK1 1
mTOR 1
eps15 1
E2F-1 1
P21 1
DAN 1
PRDX6 1
tumor necrosis factor receptor 1
cdc2-related protein kinase 1
MTA1 1
POMP 1
melanocortin 1 receptor 1
acid phosphatase 1
caspase 6 1
p20 1
carboxylating 1
DNA ligase 1
arrestin 1
RNF11 1
CDK6 1
GREM2 1
MTMR4 1
TOM1 1
TOP2B 1
YAP65 1
PEST 1
Huntingtin 1
histone methyltransferase 1
RNF213 1
RAD1 1
eIF-3 1
PIRH2 1
VACM-1 1
MAD2 1
EPHB2 1
endoglin 1
SUMO-1 1
Disease
cancer 82
tumor 55
Parkinson's disease 46
parkinsonism 29
tumorigenesis 21
Angelman syndrome 20
APC 16
breast cancer 16
hypertension 14
Liddle's syndrome 14
lung cancer 12
carcinogenesis 10
carcinoma 9
multiple myeloma 9
amyotrophic lateral sclerosis 9
dementia 8
Alzheimer's disease 8
PARK2 8
pruritus 7
lymphoma 7
adenocarcinoma 7
cervical cancer 7
abdominal aortic aneurysm 6
AAA 6
MCF 5
tumor progression 5
non-small cell lung cancer 5
mental retardation 5
autism 5
acute promyelocytic leukemia 5
mental retardation 5
Huntington's disease 5
colorectal cancer 5
muscular atrophy 5
Hippel 4
prostate cancer 4
leukemia 4
hepatocellular carcinoma 4
metastases 4
virus infection 4
neuroblastoma 4
squamous cell carcinoma 4
SDS 4
lung carcinoma 4
pancreatic cancer 3
immunodeficiency 3
melanoma 3
sepsis 3
heart failure 3
retinoblastoma 3
developmental delay 3
respiratory failure 3
ARF 3
IBR 3
Blocking 3
tumor growth 3
papilloma 3
sepsis 3
Heller 2
schizophrenia 2
cystic fibrosis 2
aggressiveness 2
metastatic melanoma 2
Japanese encephalitis 2
depression 2
cirrhosis 2
obsessive-compulsive disorder 2
Epstein 2
dysplasia 2
Kaposi's sarcoma 2
diabetes 2
gastric cancer 2
cognitive impairment 2
PML 2
Still 2
SEM 2
skin cancer 2
chronic lymphocytic leukemia 2
vaccinia 2
oral cancer 2
synovial sarcoma 2
hepatitis A 2
genetic disorder 2
ulcerative colitis 2
erythroleukemia 2
cold 2
chronic lymphocytic leukemia 2
herpes simplex 2
neurological disease 2
GSH 2
plaque 2
obesity 2
mantle cell lymphoma 2
acute myeloid leukemia 2
cardiovascular disease 2
LAP 2
glioma 2
OPA1 1
RP4 1
sleep disturbances 1
liver fibrosis 1
Rett syndrome 1
neoplastic transformation 1
IVF 1
vascular disease 1
Dementia with Lewy bodies 1
NPHP3 1
NLS 1
suicide 1
Autism 1
mammary tumor 1
adenoma 1
Machado-Joseph disease 1
Autism spectrum disorder 1
macular degeneration 1
dermatitis 1
molluscum contagiosum 1
PDB 1
chancroid 1
NS3 1
SMAX2 1
myocardial ischemia 1
proteinuria 1
Pancreas 1
Melanoma 1
ICD 1
stroke 1
cardiomyopathy 1
embryonal carcinoma 1
type 1 diabetes 1
subarachnoid hemorrhage 1
Cushing's syndrome 1
anal atresia 1
xeroderma pigmentosum 1
worms 1
coxsackievirus 1
hyperglycemia 1
severe mental retardation 1
Mycobacterium 1
choriocarcinoma 1
Azul 1
limb-girdle muscular dystrophy 1
pituitary adenoma 1
language disorder 1
chronic disease 1
malaria 1
Staring 1
Schistosoma mansoni 1
Canavan 1
myocardial infarction 1
myocarditis 1
WT1 1
carcinoma in situ 1
Dent's disease 1
arthritis 1
uremia 1
brachycephaly 1
HCG 1
XPB 1
HIV 1
muscular dystrophy 1
hepatic encephalopathy 1
epithelial ovarian cancer 1
primary tumor 1
PARK6 1
hepatitis 1
FBS 1
cutaneous melanoma 1
dehydration 1
hepatitis B 1
ovarian cancer 1
EBM 1
PHP 1
uterine cancer 1
Hodgkin's disease 1
hepatitis C 1
basal cell carcinoma 1
telangiectasia 1
cytomegalovirus 1
colitis 1
MAS 1
tuberculosis 1
PARK1 1
epilepsy 1
HGF 1
Legionella 1
adult brain tumor 1
DSS 1
ATM 1
CEM 1
RDA 1
Infection 1
CYLD 1
plant disease 1
Cockayne syndrome 1
DSS 1
mimicry 1
Anisakis 1
gastrointestinal stromal tumor 1
periodontal disease 1
motor neuron disease 1
RP11 1
Brown 1
scrotum 1
lymphoblastic leukemia 1
colon cancer 1
dyslipidemia 1
periodontitis 1
Spinocerebellar ataxia 1
stromal tumors 1
infectious diseases 1
Cholangiocarcinoma 1
SCID 1
azoospermia 1
Juvenile Parkinsonism 1
riboflavin deficiency 1
male infertility 1
pancreatitis 1
Pancreas 1
confusion 1
CRV 1
dilated cardiomyopathy 1
renal cancer 1
bipolar disorder 1
inflammatory bowel disease 1
achalasia 1
esophageal atresia 1
viral diarrhea 1
Cholangiocarcinoma 1
metastatic breast cancer 1
glaucoma 1
Crohn's disease 1
renal hypertension 1
solid tumor 1
glioblastoma 1
adult T-cell leukemia/lymphoma 1
leukodystrophy 1
scoliosis 1
hematologic malignancies 1
glioblastoma multiforme 1
Symptom
seizures 9
starvation 7
ataxia 5
collapse 2
weakness 2
tremor 2
overweight 1
cerebellar ataxia 1
functional recovery 1
dystonia 1
ataxic gait 1
acidity 1
hypotonia 1
Drug
Parkin 43
Parkin 43
lysine 34
Bortezomib 4
TAK 2
GEO 2
uPA 1
Dermatol 1
Alanine 1
IL-2 1
Glutathione 1
CPT-11 1
CSF 1
Arsenic trioxide 1
caffeine 1
CIA 1
NADH 1
Dasatinib 1
Ginseng 1
Taxol 1
CoCl2 1
CoCl2 1
Jujube 1
Retinoic acid 1
Pirarubicin 1
ICI 1
AMC 1
nitroglycerin 1
Kenyan 1
Heme 1
Enzyme
ubiquitin-protein ligase 799
proteasome 188
protein kinase 26
APC 18
ERK 14
RNA polymerase 13
ATPase 12
mitogen-activated protein kinase 10
lysozyme 8
glutathione S-transferase 7
luciferase 7
caspase-3 7
isopeptidase 6
IKK 5
cdc2 5
protein kinase C 4
3C protease 4
calcineurin 4
RNase 4
complex I 4
transcriptase 3
superoxide dismutase 3
trypsin 3
PARP 3
focal adhesion kinase 3
ubiquityl-calmodulin synthetase 3
diaphorase 2
diacylglycerol kinase 2
enolase 2
beta-galactosidase 2
granzyme B 2
trehalase 2
protein phosphatase 2A 2
phospholipase C 2
DNA ligase 2
ornithine decarboxylase 2
phosphoinositide 3-kinase 2
aminopeptidase I 2
hexokinase 2
leucine aminopeptidase 2
reverse transcriptase 2
topoisomerase 2
ribonuclease 2
NADH dehydrogenase 2
RNase 2
DNA ligase 2
m-calpain 2
arginyl-tRNA synthetase 2
ribonuclease 2
carbonic anhydrase 1
AMP-activated protein kinase 1
transketolase 1
ACS 1
DNase 1
glucose-6-phosphate dehydrogenase 1
IscS 1
cystathionine beta-synthase 1
renin 1
heme oxygenase 1
E-2 1
cytochrome oxidase 1
chaperonin 1
chorismate mutase 1
cathepsin D 1
DNA polymerase 1
isocitrate dehydrogenase 1
beta-glucosidase 1
lipase 1
ECH 1
chymotrypsin 1
NQO1 1
proteinase K 1
ATP synthase 1
furin 1
endonuclease 1
NO synthase 1
prostate-specific antigen 1
isocitrate dehydrogenase 1
phosphodiesterase 1
type 1 protein phosphatase 1
TSP-1 1
CD10 1
acid phosphatase 1
phospholipase A2 1
galactinol synthase 1
MMP 1
3-hydroxy-3-methylglutaryl-CoA reductase 1
cysteine synthase 1
TOR 1
arginase 1
3-hydroxybutyryl-CoA dehydrogenase 1
ricin 1
caspase-8 1
beta-glucuronidase 1
separase 1
caspase-9 1
S-adenosyl-L-homocysteine hydrolase 1
5,10-methenyltetrahydrofolate synthetase 1
alpha-ketoglutarate dehydrogenase 1
topoisomerase 1
lactate dehydrogenase 1
AMPK 1
lipoxygenase 1
3-hydroxyacyl-CoA dehydrogenase 1
aldolase 1
p80 1
cathepsin L 1
farnesyltransferase 1
MDP 1
CaMKII 1
glycerol kinase 1
PNGase F 1
polo-like kinase 1 1
alcohol dehydrogenase 1
glutaminase 1
DNA methyltransferase 1
caspase-1 1
fatty acid desaturase 1
histone acetyltransferase 1
thioredoxin reductase 1
Compound
DNA 71
Dec 54
lysine 53
ATP 52
Ubiquitin 43
cysteine 26
sodium 26
Cbl 18
arginine 18
tyrosine 17
salt 16
zinc 16
serine 14
aldosterone 14
calcium 12
leucine 12
methionine 11
alanine 10
threonine 10
retinoic acid 9
glucose 9
nitrogen 9
water 8
His 8
NH2 8
AMP 8
Gly 8
pyrimidine 7
Clin 7
PYR 7
adenylate 7
AAA 6
Phe 6
sulfate 6
Ile 5
nitric oxide 5
PPi 5
cAMP 5
NAD 4
NAD 4
aldehyde 4
SDS 4
aldehyde 4
proline 4
Asp 4
ammonium 4
DEAE 4
RUB 3
glutamate 3
iron 3
GSH 3
H2O2 3
GTP 3
cyanide 3
urea 3
oxygen 3
Cycloheximide 3
GSH 3
TNM 3
MDA 3
hydrogen 2
cadmium 2
AICAR 2
tryptophan 2
L-DOPA 2
tryptophan 2
Mg2+ 2
bromide 2
isoleucine 2
tryptophan 2
Glycogen synthase 2
molybdenum 2
galactose 2
Cardiol 2
GSSG 2
40S 2
TNF 2
ethanol 2
silver 2
aniline 2
CHIP 2
AICAR 2
COS 2
isoleucine 2
tryptophan 2
IAA 1
boron 1
Vinclozolin 1
butyric acid 1
Arsenite 1
Methamphetamine 1
GDP 1
ubiquinone 1
MAD 1
HCO 1
hydrazine 1
Cortisone 1
phosphorus 1
phosphate 1
alcohol dehydrogenase 1
hexane 1
BMC 1
butyric acid 1
DGE 1
Melatonin 1
NADPH 1
Rapamycin 1
nicotinic acid 1
quinoline 1
methanethiol 1
Methyl caffeate 1
Guanine 1
MPTP 1
Casein 1
ethyl acetate 1
Vasopressin 1
ACS 1
manganese 1
salicylic acid 1
Cholesterol 1
DSS 1
titanium 1
succinic acid 1
Phytol 1
ATF 1
TOF 1
valine 1
Arachidonic acid 1
3-methylhistidine 1
nicotinic acid 1
Brefeldin A 1
DBT 1
CPT-11 1
PDB 1
Perillyl alcohol 1
Phytol 1
uridine 1
FK506 1
Quercetin 1
Collagen 1
Heme 1
DGE 1
NADH 1
DEP 1
Dopamine 1
hydroxylamine 1
5-Azacytidine 1
GABA 1
GABA 1
Perillyl alcohol 1
myricetin 1
Arabinogalactan 1
3-fluoropyridine 1
Isoform 1
E-64 1
MMC 1
Artemisinin 1
NADPH 1
DEP 1
ABA 1
DPP 1
GAL 1
1,4-cyclohexanedione 1
ICI 1
pyrrolidine 1
retinol 1
EMS 1
adenosylmethionine 1
iodine 1
pyrrolidine 1
Cortisol 1
THP 1
glycerol 1
benzoic acid 1
SSH 1
nicotinic acid 1
malononitrile 1
5-HT 1
Brefeldin A 1
ABA 1
nickel 1
APH 1
DGE 1
creatinine 1
C2H2 1
Uracil 1
CCP 1
isopentenyl diphosphate 1
DMPP 1
ACS 1
AF-2 1
methanol 1
THP 1
BCNU 1
DTT 1
glutamine 1
quinoline 1
MTT 1
butyric acid 1
glutamic acid 1
Embelin 1
Pac 1
hydroxylamine 1
DTT 1
SN-38 1
APAP 1
G 1 1
IAA 1
nicotinic acid 1
Alanine 1
caffeine 1
DOC 1
Leucine 1
POP 1