Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.2.1.7 (
BAL
)
1,977
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
To evaluate the penetration of theophylline into the airways its concentration (
Theo-Dur
, Astra, Sweden) was determined in
BAL
and in serum in 20 patients with atopic bronchial asthma, 24 patients with chronic bronchitis and 5 smokers as controls. The results were statistically analyzed. Slow-release theophylline in
Theo-Dur
was well tolerated. The mean concentrations of theophylline in
BAL
and serum in all analyzed groups were similar, but theophylline concentration in
BAL
was 1/3 of serum value. Moreover, the low correlation between concentrations of theophylline in
BAL
and serum was detected. The calculation of theophylline values in relation to total protein or albumin is not recommended.
...
PMID:Theophylline in serum and in bronchoalveolar lavage (BAL) in atopic bronchial asthma and chronic bronchitis. 275 Jun 38
