Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.2.1.7 (
BAL
)
1,977
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Multicentric
Castleman's disease
(MCD) is a rare and often incurable lymphoproliferative disorder. It is typically a systemic illness, but occasionally manifests primarily as a pulmonary parenchymal disease with massive infiltration of CD138 (syndecan-1)-positive plasma cells. This is the first report to demonstrate a marked elevation of soluble CD138, despite the absence of plasma cells, in
BAL
fluid in an MCD patient with pulmonary involvement. This finding suggests that the quantitative measurement of soluble CD138 in
BAL
fluid may reflect plasma cell infiltration and disease activity in the lungs of patients with MCD.
...
PMID:Increase in soluble CD138 in bronchoalveolar lavage fluid of multicentric Castleman's disease. 1720 40
