Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:6.2.1.1 (
ACS
)
78,556
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ACS
78058
Sep
5683
hole
1890
NMR
1213
PEG
799
TEM
587
serum albumin
533
Pseudomonas
479
fused
466
PSS
455
collagen
442
ATP
437
acetyl-CoA synthetase
408
NIR
333
osteogenic
317
AFM
313
Poly
291
PVA
276
peroxidase
263
MOF
239
cytokine
231
CO2
230
insulin
228
GSH
220
cage
214
dilute
197
C-C
193
RHE
192
PEO
181
PCL
172
BET
170
histone
164
alkaline phosphatase
160
lipopolysaccharide
157
Raf-1
151
polypeptide
144
lysozyme
143
albumin
141
synuclein
140
MRI
136
endoplasmic reticulum
134
PLA
132
dimeric
131
TNF
128
SARS
122
gut
120
caspase-3
117
TOF
116
epidermal growth factor receptor
114
fibronectin
114
MIC
114
NAD
111
SAR
108
hemoglobin
108
catalase
108
TGA
108
glycoprotein
107
tRNA
107
reductase
107
p53
105
SERS
105
thrombin
105
lamp
102
tap
102
opioid receptor
101
FTO
99
acetylcholinesterase
95
methyltransferase
95
CIE
93
PBS
93
ADP
93
AMP
92
CD44
92
twist
90
amyloid precursor protein
89
membrane protein
89
fibrinogen
89
P25
88
ROS
87
proteasome
87
LDH
86
vascular endothelial growth factor
86
ubiquitin
86
ATPase
85
G protein-coupled receptor
85
GABA
85
cytochrome P450
84
mer
82
IL-6
82
CD8
80
HEK
79
NADH
77
lectin
77
histone deacetylase
76
tumor necrosis factor
75
superoxide dismutase
74
amyloid beta
73
NADPH
73
Mol
72
ferritin
70
ATR
70
threonine
69
DSC
68
Bcl-2
68
phosphatase
67
scratch
67
cytochrome
67
P-glycoprotein
66
membrane-bound
66
lipase
66
STM
64
E. coli)
62
ICP
62
hinge
62
matrix metalloproteinase
61
PCI
61
VEGF
60
alcohol dehydrogenase
60
ERK1
59
axonal
59
CD4
59
asymmetrical
59
mTOR
59
IFN
59
kit
58
MAS
58
PI3K
57
tyrosine kinase
56
esterase
56
transferrin
56
ALD
55
MAPK
55
EGFR
54
ERK
54
osteocalcin
54
EPR
54
cryptic
54
HER2
53
histone H3
53
ash
53
glucosamine
53
Boc
52
prion
52
cytochrome c
52
SOD
52
THP
51
ESI
51
PAH
50
lactate dehydrogenase
50
P450
50
catenin
50
Spin
49
PCC
49
binding peptide
49
interleukin-6
49
MCM
49
estrogen receptor
47
AKT
47
prostate-specific antigen
47
endonuclease
46
more...
Disease
cancer
3759
tumor
2816
Alzheimer's disease
861
TEM
592
TEM
587
breast cancer
581
SEM
522
tumor growth
471
PSS
457
PSS
455
PSS
455
Parkinson's disease
326
tuberculosis
303
MCF
300
myocardial infarction
275
Mycobacterium
265
diabetes
259
HIV
238
cold
220
GSH
220
cardiovascular disease
208
depression
206
RHE
192
PAA
191
infectious diseases
189
prostate cancer
184
melanoma
174
stroke
173
PCL
172
dehydration
161
lung cancer
151
hepatocellular carcinoma
150
carcinoma
141
SARS
139
malaria
135
plaque
133
glioma
121
influenza
120
coronary artery disease
117
ischemia
114
atherosclerosis
113
schizophrenia
109
SAR
108
mole
108
obesity
107
mole
106
bacterial infection
105
conversion reaction
105
glioblastoma
104
neuroblastoma
102
dementia
94
leukemia
93
CIE
93
fits
89
pancreatic cancer
87
type 2 diabetes
87
hypertension
86
metastases
86
tumor progression
85
adenocarcinoma
84
virus infection
82
WS2
80
colorectal cancer
79
photosensitivity
78
epilepsy
78
addiction
77
ovarian cancer
76
heart failure
76
liver cancer
75
unstable angina
70
acute myocardial infarction
67
tumorigenesis
67
brain tumor
66
hepatitis C
66
cervical cancer
66
colon cancer
65
immunodeficiency
65
multiple sclerosis
64
pheochromocytoma
62
ICP
62
hepatitis B
61
liver cancer
60
solid tumor
60
Klebsiella
59
MAS
58
rheumatoid arthritis
57
sepsis
57
cholera
56
ALD
55
amyotrophic lateral sclerosis
54
cognitive impairment
54
ash
53
STEMI
53
sepsis
53
primary tumor
52
PCC
52
Fabry
52
dengue
51
arthritis
51
Adhesion
51
cystic fibrosis
49
Huntington's disease
48
non-small cell lung cancer
46
myocardial ischemia
45
SDS
45
osteosarcoma
45
glioblastoma multiforme
45
ACS1
43
asthma
43
Still
42
mimicry
41
Infection
40
acute myeloid leukemia
40
worms
39
pneumonia
39
leprosy
38
osteoarthritis
38
chronic pain
38
NHS
37
MRSA
37
lung carcinoma
35
CNS diseases
35
EDC
35
leishmaniasis
34
NS3
34
cerebral ischemia
32
suicide
32
PAM
32
Acute coronary syndrome
32
PGA
31
autism
31
glaucoma
30
HTS
30
heart disease
29
lymphoma
29
ACP
28
autoimmune disease
28
osteoporosis
28
anthrax
28
Blocking
28
African trypanosomiasis
28
PDB
27
cirrhosis
27
sickle cell disease
27
squamous cell carcinoma
27
tumor vasculature
27
gastric cancer
27
bladder cancer
27
skin cancer
27
coronary heart disease
27
BDC
27
MIP
26
Chagas
26
inflammatory bowel disease
26
multiple myeloma
25
CNF
25
amyloidosis
25
hyperglycemia
25
Infections
25
metastatic breast cancer
25
more...
Symptom
pain
232
collapse
226
acidity
204
fatigue
149
thinning
143
starvation
59
seizures
55
agitation
51
angina
46
chest pain
41
tremor
37
analgesia
34
weakness
28
diarrhea
27
HSA
23
functional recovery
22
memory loss
19
flushing
19
anesthesia
18
hypothermia
17
discomfort
16
discomfort
16
cough
14
exhaustion
12
dyspnea
11
constipation
11
skin irritation
11
vomiting
10
ataxia
9
insomnia
9
headache
8
nausea
8
anosmia
7
bradykinesia
7
halitosis
7
microbial colonization
6
sleepiness
6
anorexia
5
dizziness
5
respiratory distress
5
cachexia
5
dry eye
4
acute stress
4
Scratch
4
Halo
4
muscle stiffness
4
acute pain
4
overweight
4
Buckling
3
tense
3
arthralgia
3
Neuropathic pain
3
Ill
3
rundown
3
erythema
3
back pain
3
stigma
3
chills
3
dry skin
3
regurgitation
3
skin damage
3
forgetfulness
2
Inflammatory pain
2
GI irritation
2
No adverse effect
2
Acute chest pain
2
Stiffness
2
despair
2
incoordination
2
dysosmia
2
bitter taste
2
vertigo
2
abdominal pain
2
twitching
2
nerve pain
2
exertional dyspnea
2
paresthesia
2
spasticity
2
asynergy
2
shortness of breath
2
loss of taste
2
bone pain
1
Sedation
1
ACHE
1
chronic constipation
1
cerebellar ataxia
1
low back pain
1
paraparesis
1
Catch
1
alexithymia
1
Burning
1
Excitable
1
apathy
1
CSR
1
photophobia
1
nausea and vomiting
1
syncope
1
physical appearance
1
tinnitus
1
motor symptom
1
distraction
1
Spotting
1
dysuria
1
hypersomnia
1
nasal congestion
1
neuralgia
1
sore throat
1
Fluctuation
1
bedwetting
1
blackout
1
blurred vision
1
joint stiffness
1
mental fatigue
1
Spots
1
flank pain
1
sneezing
1
Wind
1
eds
1
spasm
1
hyperoxia
1
musculoskeletal chest pain
1
rigors
1
livedo
1
hemiplegia
1
catatonia
1
hemoptysis
1
lethargy
1
orofacial pain
1
myalgia
1
chronic back pain
1
general problem
1
PUO
1
neck stiffness
1
cancer pain
1
splenomegaly
1
hunger
1
hypercapnia
1
wheezing
1
Drug
ZnO
1354
TiO2
785
lysine
491
SiO2
353
MOF
238
MIL
147
citric acid
102
ROS
87
Silica
80
NADH
77
NH3
71
Cardiovasc
60
ascorbate
59
THF
56
Gel
56
Asn
40
lactose
39
BTC
38
TAT
38
ADR
34
caffeine
30
ABC
29
FAD
29
ampicillin
28
Taxol
27
Leaf
27
Mutagen
26
TFT
26
MAP
26
Ethanol
25
Bayer
24
CSF
21
Monit
21
Fragment
20
ENT
20
Clopidogrel
20
IL-2
20
PCB
19
NVP
19
vitamin E
19
FeCl3
18
Albumin
18
nitroglycerin
17
ROC
17
DPA
17
CAM
17
Itraconazole
16
CTX
16
Gelatin
16
ALA
15
ADM
15
Glutathione
14
NaI
14
NaI
14
NaI
14
EPA
14
pyridoxal phosphate
14
PCP
14
NaI
14
CaCl2
13
CaCl2
13
Fluorescein
13
DM1
13
RFP
13
Herceptin
13
CaCl2
13
ZnCl2
12
Adenosine triphosphate
12
DNase I
12
ZnCl2
12
Alanine
12
Methylene blue
12
Spectrum
11
ETA
11
PPA
11
CTX
10
CTX
10
Fluorescein
10
TMS
10
Meropenem
10
Triclosan
9
Magnevist
9
-deoxyadenosine
9
Adriamycin
9
Heme
9
Sorafenib
8
ACT
8
Meropenem
8
PZC
8
MRC
8
PTC
7
BH4
7
TAK
7
CDP
7
TES
7
Retinoic acid
7
InCl3
7
MgSO4
7
Sodium alginate
7
DMAP
7
Glycerol
7
Tannic acid
7
HCH
6
AMC
6
EPI
6
TTC
6
Docetaxel
6
Aloe
6
Flavin
6
niacin
6
Galactose
6
AZT
6
PMEA
5
Bexarotene
5
Award
5
Biopolymers
5
BoNT/A
5
ICI
5
Bivalirudin
5
Fondaparinux
5
VCR
5
CTA
5
Vorinostat
5
Compound 9
5
Imatinib
5
Glide
5
PFA
5
Glucagon
5
Hyaluronidase
5
PFT
5
MEA
5
AHF
5
SF6
5
Simvastatin
4
p75
4
Fosmidomycin
4
ROX
4
Orphan
4
Helium
4
FLP
4
Parkin
4
Indocyanine green
4
Eptifibatide
4
Crystal Violet
4
Auranofin
4
Android
4
Photofrin
4
Parkin
4
Resovist
4
Vitamin A
4
Acacia
4
Cellulose acetate
4
Vitamin B
4
CPO
4
DHT
4
NBT
4
G418
4
EML
4
AZT
4
Bortezomib
4
more...
Enzyme
ACS
78556
ERK
476
acetyl-CoA synthetase
451
peroxidase
340
glucose oxidase
189
mitogen-activated protein kinase
175
protein kinase
171
alkaline phosphatase
160
lysozyme
144
focal adhesion kinase
138
luciferase
137
catalase
119
thrombin
107
acetylcholinesterase
101
proteasome
96
RNA polymerase
91
ATPase
90
superoxide dismutase
87
caspase-3
81
PCE
80
trypsin
78
lipase
70
P-glycoprotein
66
pyruvate dehydrogenase
65
alcohol dehydrogenase
65
acyl-CoA synthetase
65
lactate dehydrogenase
51
DNA polymerase
50
laccase
50
PAH
50
PTA
49
aldehyde dehydrogenase
48
reverse transcriptase
47
endonuclease
46
RNase
42
PARP
42
prostate-specific antigen
42
carbonic anhydrase
41
dihydrofolate reductase
40
topoisomerase
39
TAT
38
GSK
38
topoisomerase
38
hyaluronidase
37
acetate kinase
37
hyaluronidase
35
acyl-CoA synthetase
34
aldehyde dehydrogenase
34
CAD
34
pyruvate dehydrogenase
33
pyruvate dehydrogenase
33
MEK
33
CAD
32
phosphodiesterase
32
PAM
32
CAD
32
thromboplastin
31
protein kinase C
30
firefly luciferase
30
ACC synthase
30
cholinesterase
30
hydrogenase
29
TPP
29
aldehyde dehydrogenase
29
TPP
29
hydrogenase
28
isocitrate lyase
28
RNase
28
calcineurin
28
aldehyde dehydrogenase
28
aldehyde dehydrogenase
28
cathepsin B
27
urease
26
urease
26
neuraminidase
26
chymotrypsin
26
CPT
26
creatine kinase
26
acetyl-CoA carboxylase
26
citrate synthase
25
kinesin
25
prostate-specific membrane antigen
24
monoamine oxidase
24
ACE
24
CPT
24
glutathione S-transferase
24
DAT
24
CPT
24
collagenase
24
pyruvate decarboxylase
23
aspartate aminotransferase
23
tyrosinase
23
fatty acid elongase
22
alanine aminotransferase
21
tyrosine hydroxylase
21
demethylase
21
CO dehydrogenase
21
aldolase
21
MIP
21
AMP-activated protein kinase
21
papain
20
caspase-1
20
pyruvate kinase
20
malate dehydrogenase
20
cellulase
20
transglutaminase
19
HIV-1 protease
19
glucose dehydrogenase
18
phosphoinositide 3-kinase
18
ACC oxidase
18
MDR
18
DNase
18
complex I
18
caspase-9
17
isocitrate dehydrogenase
17
glucose-6-phosphate dehydrogenase
17
glutathione peroxidase
17
NQO1
17
transcriptase
16
LasR
16
isocitrate dehydrogenase
16
paraoxonase
16
arginase
16
glutamate dehydrogenase
16
prenyltransferase
16
phosphoenolpyruvate carboxykinase
15
deaminase
15
malate synthase
15
polo-like kinase 1
15
phospholipase A2
15
ATP synthase
15
DTA
15
phosphoenolpyruvate carboxykinase
15
prenyltransferase
14
AMPK
14
ricin
14
PCP
14
prenyltransferase
14
angiotensin-converting enzyme 2
14
CYP3A4
14
soluble epoxide hydrolase
14
histidine kinase
14
MAP
14
phosphoenolpyruvate carboxykinase
13
transpeptidase
13
glutamate dehydrogenase
13
elastase
13
APC
13
halogenase
13
urokinase-type plasminogen activator
13
DNA ligase
13
DNA ligase
13
glutamate dehydrogenase
13
MPP
13
ribonuclease
12
lactate oxidase
12
ribonuclease
12
indoleamine 2,3-dioxygenase
12
thioredoxin reductase
12
pyruvate:ferredoxin oxidoreductase
12
more...
Compound
ACS
78058
ACS
78058
water
8778
Dec
5263
oxygen
5226
hydrogen
3962
DNA
3013
silicon
2182
nitrogen
1877
PEG
1811
iron
1678
silver
1658
sodium
1593
copper
1542
PEG
1433
salt
1269
zinc
1189
glucose
1082
phosphate
1029
tin
1011
ethanol
911
nickel
817
aluminum
795
calcium
777
titanium
769
boron
749
cobalt
730
methanol
701
vinyl
685
acetate
669
CO2
647
TEM
628
lysine
590
iodine
590
molybdenum
583
ammonium
551
fluorine
541
hydroxide
515
carbonate
510
bromide
501
cysteine
494
phosphorus
473
ammonia
460
sulfate
453
ATP
438
NH2
436
potassium
421
thiophene
409
arginine
408
KOH
406
benzene
400
manganese
394
pyridine
388
SiO2
377
acrylic acid
375
Carbon
369
butyric acid
358
butyric acid
357
butyric acid
357
urea
347
tungsten
334
methane
318
nitrate
310
nitric oxide
308
toluene
307
selenium
290
tyrosine
288
PVA
287
acetone
280
Lithium
271
aldehyde
261
vanadium
261
glutamate
261
His
253
alanine
253
Phe
252
CuO
242
phenol
237
acetyl-CoA
235
hyaluronic acid
233
CoA
231
N-isopropylacrylamide
231
GSH
225
GSH
225
Asp
224
glycerol
218
serine
217
acetic acid
211
galactose
211
DMF
210
MDA
206
acrylamide
205
aldehyde
204
formaldehyde
203
formaldehyde
199
HCl
196
THF
195
aniline
194
PAA
191
perylene
183
hydrazine
179
H2O2
178
pyrene
176
cadmium
167
tryptophan
162
acetonitrile
161
PEI
159
PEI
159
Cu(II)
159
5-HT
157
pyrimidine
157
Gly
155
tryptophan
152
tryptophan
152
tryptophan
152
pyrimidine
150
DMSO
149
Cardiol
147
naphthalene
146
chlorine
146
sulfuric acid
146
mercury
146
MTT
145
Clin
145
MgO
144
chloroform
141
germanium
136
formic acid
135
hexane
135
formic acid
134
formic acid
134
formic acid
134
formic acid
134
formic acid
134
formic acid
134
formic acid
134
formic acid
134
formic acid
134
pentacene
133
PVP
133
isopropanol
131
PLA
130
chromium
129
TNF
128
PNP
127
H2S
125
NAD
121
threonine
117
TOF
116
Sodium
115
MIC
115
ADP
113
NAD
111
2-ethylhexyl
110
2-ethylhexyl
110
2-ethylhexyl
110
methionine
108
leucine
107
Rhodamine B
105
Lead
105
more...