Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.2.1.1 (ACS)
 78,556 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Plant growth and development is controlled by a set of hormones whose responses are tightly regulated in order to direct appropriate responses. In several hormone signaling pathways, protein turnover has emerged as a common regulatory element. Ethylene is a phytohormone that controls a variety of processes, including fruit ripening, senescence, and stress response. This review focuses on the regulation of the ethylene response pathway through protein degradation. Protein turnover has been found to regulate both ethylene biosynthesis and ethylene response. Ethylene production is regulated through the turnover of the biosynthetic enzyme ACS. Recently it was found that ethylene receptors are controlled by protein turnover as well. A third process in the control of ethylene signaling is the targeting of the ethylene response transcription factor ETHYLENE INSENSITIVE3 (EIN3) for degradation by the proteins EIN3-BINDING F-BOX 1 and 2 (EBF1 and EBF2).
 ...
PMID:The role of protein turnover in ethylene biosynthesis and response. 1865 Sep 58