Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:6.2.1.1 (ACS)
 78,556 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The primary purpose of this session was to recognize the outstanding achievements in the field of medicinal chemistry. The ACS award for Creative Invention went to researchers at Merck and Co Inc, who successfully developed Crixivan (indinavir, L-735524), an HIV-1 protease inhibitor, which received FDA approval in record time and is now used by over 300,000 patients worldwide. A former Merck scientist, John Baldwin (Pharmacopeia Inc, USA), was honored with the EB Hershberg award for Important Discoveries in Medicinally Active Substances. Dr Hershberg has been at the forefront of drug discovery technologies, such as combinatorial chemistry and rational drug design. During his 30-year career at Merck, he was involved with the Pepcid, Crixivan and Trusopt projects, but eventually left in 1993 when he co-founded Pharmacopeia.
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PMID:Division of Medicinal Chemistry--general oral session/fellowship awards. 1612 4