Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.2.1.1 (ACS)
 78,556 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Coronary angioplasty (PTCA) through 6 French (F) guiding catheters is feasible, although acute or threatened closure following coronary artery dissections may occur. This report describes our experience with the treatment of suboptimal results in 13 patients from a population of 144 patients who had PTCA through 6F guiding catheters. Patients were treated with a new low profile autoperfusion catheter (ACS, Flowtrack40) or with Palmaz Schatz stents, advanced through 6F guiding catheters. PTCA was performed via the radial artery in 11 pts (85%) or via the femoral artery in two patients (15%). In two patients, (15%) PTCA was complicated by an dissection associated with complete loss of flow (TIMI 0) and a dissection was considered to lead to abrupt closure in the remaining 11 patients (85%), despite the presence of normal flow. A Flow-track40 perfusion catheter was successfully applied in three of four patients. In one patient a persisting dissection after restoration of flow by a perfusion catheter was treated with three Palmaz Schatz stents. Implantation of Palmaz Schatz stents was attempted as primary technique in nine patients. In one patient the stent could not cross a dissection in the proximal LAD via the radial artery. With an 8F system via the femoral artery, two stents could successfully be deployed with the stent delivery system. In another patient the stent could not be advanced across a subtotal residual stenosis in a tortuous left anterior descending coronary artery. Despite normal antegrade flow and emergency bypass surgery, this patient developed a non-Q-myocardial infarction. In the remaining patients, the clinical course was uncomplicated.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:Bailout techniques for failed coronary angioplasty using 6 French guiding catheters. 798 20

The aim of this study was to verify the feasibility of a respiratory motion compensation technique (motion-adapted gating, MAG) for visualization of coronary arteries (CA) by correlation with selective coronary angiography (SCA). Fifteen subjects (11 patients, mean age 61.3 years, age range 41-73 years; and 4 healthy volunteers, mean age 32.3 years, age range 31-35 years) were investigated. A Philips Gyroscan ACS-NT was used, operating at 1.5 T, was combined with the PowerTrak 6000 gradient system. An ECG-triggered, respiratory motion-gated 3D turbo field echo sequence was used. The real-time algorithm utilized the concept of k-space weighting in combination with automatic analysis of respiratory motion. The main CA were investigated. Qualitative analysis was performed by three blinded investigators. Visibility was graded on a five-point scale (0=not visualized, 1=insufficient, 2=sufficient, 3=good, 4=excellent). Segments graded 2-4 were defined as adequately visualized. Sixty-two of 88 assessable CA segments in patient, and 22 of 32 in volunteer group were adequately visualized. Visibility of CA was classified as excellent for proximal RCA (avg. 3.6+/-0.5), good for LM, proximal LAD, proximal LCX, middle RCA and sufficient for middle LAD. Sensitivity, specificity, positive and negative predictive values for coronary MRA in detection of CA stenoses with luminal narrowing >/=50% were 88, 94, 83, and 96%, respectively. Magnetic resonance imaging in combination with MAG has proven to be a promising technique for noninvasive imaging of CA due to good image quality and a patient convenient free-breathing technique.
 ...
PMID:Correlation of 3D MR coronary angiography with selective coronary angiography: feasibility of the motion-adapted gating technique. 1196 Feb 17

A young woman admitted with a diagnosis of NSTE-ACS underwent coronary angiography which showed LAD spontaneous coronary artery dissection treated with magnesium-made bioresorbable scaffold. We report 1-year angiographic and OCT findings.
 ...
PMID:Spontaneous coronary artery dissection treated with magnesium-made bioresorbable scaffold: 1-Year angiographic and optical coherence tomography follow-up. 3041 4