Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:6.2.1.1 (ACS)
 78,556 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The person who has been treated for cancer may have unique problems resuming employment or starting a new job. Cancer represents a spectrum of diseases, and posttreatment impairments may vary from none, in the majority of cases, to major functional disability. Employers understandably have difficulty recognizing the variability that exists, both in terms of functional capacity and prognosis, and they are often unaware of the improved prognosis for many cancers. Today, many patients receive adjuvant chemotherapy or prolonged intermittent treatment and need to adjust their work schedule to allow for this. Some people need job training or vocational counseling; in many states, vocational rehabilitation agencies now have an increased interest in providing services to cancer patients. Discrimination against the cancer patient has been demonstrated; the major problems are in the area of hiring practices. Efforts need to be continued to educate employers and the public and to ensure that the rights of the cancer patient are recognized. We may, however, do our patients a disservice if we overemphasize potential problems to a degree that increases patient fear and insecurity in regard to employment. Instead, we as physicians may be able to help prevent problems by more effective communication with employers on behalf of our patients, as well as by direct patient counseling. The insurance problems of cancer patients, particularly those relating to health insurance, do require major attention. The potential productivity, as well as the quality of life, of the cancer patient are jeopardized when he or she feels unable to change jobs because of fear of loss of insurance coverage. The relatively high number of reported cancellations and changes in insurance benefits that have been reported by cancer patients also represents an area of concern, since some of these appear medically unjustified. The physician's opinion and input may be of importance in preventing or solving individual insurance problems. The physician can also help the cancer patient who has employment problems by providing information about available resources. The above-mentioned employment booklet (#4585-PS), available from the ACS, may be useful and contains information about legal resources. Referral to a vocational rehabilitation agency may be indicated. The best medicine of all may be a positive and optimistic attitude toward the patient's participation in the work force.
 ...
PMID:The cancer patient at work. 393 69

One hundred twenty-six consecutive ACS Category I motor vehicle trauma patients transported by helicopter from 25 hospitals to a regional trauma center in rural Pennsylvania during a 14-month period were reviewed retrospectively. The overall mortality was 13%. Average round-trip distance was 79 miles. Interventions by the medical flight team (emergency physician/nurse) included endotracheal intubation, tube thoracostomy, and/or central venous access in 42 patients (33%) prior to lift-off. Ground time at the referring facility, from landing to lift-off, when no interventions were required of the flight team, averaged 31.2 minutes (baseline). Ground time when major therapeutic interventions were required (principally airway management), however, averaged 57.4 minutes, an 84% increase over baseline (P less than .01). A major cause of the excessive ground times was the lack of standardized diagnostic workup and stabilization of patients prior to arrival of the flight team. Recommendations for standardized emergency department preparation of trauma victims requiring aeromedical evacuation are made.
 ...
PMID:Rural interhospital helicopter transport of motor vehicle trauma victims: causes for delays and recommendations. 395 81

A patient presented with an acute inferior myocardial infarction. Coronary angiography in the acute stage revealed total occlusion of the right coronary artery. Reperfusion was obtained after intracoronary infusion of 250,000 units of streptokinase. Angioplasty was subsequently performed because of a high grade residual stenosis. An 8-French right Judkins guiding catheter with a single side hole (USCI), a 3.0 mm balloon dilatation catheter (ACS), and a 0.018 high torque floppy guide wire (ACS) were used. After successful angioplasty angiography was repeated with the guide wire in the RCA, but the balloon was withdrawn into the guiding catheter. After injection of contrast, it was impossible to withdrawn the balloon catheter out of the guiding catheter. Fluoroscopy revealed extrusion of the balloon through the side hole in the guiding catheter.
 ...
PMID:Inadvertant balloon extrusion through a side hole in a guiding catheter. 395 42

The requirement for external Ca (Cao) of neurotransmitter release evoked by cardenolides has been investigated in canine saphenous vein. Basal efflux of 3H-compounds from saphenous veins pre-loaded with 3H-noradrenaline was the same in the absence as in the presence of Cao; Cao is not required for basal efflux of neurotransmitter. Efflux of 3H-compounds was increased by cardenolides. Both ACS and ouabain caused a similar maximum net efflux of 3H suggesting that each evokes release from the same pool of 3H compounds. The similarity of the effects obtained with cardenolides to those obtained during exposure of saphenous vein preparations to potassium-free media suggests that 3H-efflux is the result of Na,K-ATPase inhibition. With ACS (ca. EC50) the net efflux of 3H-compounds early (less than 60 min) in the release period was greater in the absence of Cao than in its presence whereas at longer times the reverse was true; net efflux was less in the absence of Cao than in its presence. The difference in the 3H-efflux pattern was paralleled qualitatively throughout by efflux of 3H-noradrenaline. The ACS-evoked efflux of 3H-compounds in the presence and absence of Cao derives from sympathetic, noradrenergic nerves; 3H present in extraneuronal tissues was not released by the cardenolide. With ouabain (less than EC50) the total efflux of 3H over a 75 min period was greater in the absence of Cao than in its presence. The reverse was found with ouabain (greater than EC50): the total efflux of 3H was less in the absence of Cao than in its presence.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:Cardiac glycosides, calcium and the release of neurotransmitter from peripheral noradrenergic nerves. 400 Feb 81

In 1984 the Poison Center installed a Dacon ACS-46 Automatic Call Sequencer. This device is connected to all incoming poison information lines (with the exception of a specially designated 911 line) and acts as an interface between callers and Poison Information Specialists during periods of heavy call loads. While the use of a call sequencer could never be termed ideal, such use offers a number of specific benefits in situations that are frequently encountered in Poison Center work. These benefits include: significant reduction in staff stress, caller assurance that a correct number has been reached, efficient triage of incoming calls, and accumulation of accurate incoming call data. Data input parameters of this system include: total calls offered, dropped calls, calls over alarm time, average time for completed calls, average time for dropped calls, and completed and dropped hold time data bins.
 ...
PMID:Use of a line card sequencer for triage of poison center calls. 408 64

Balloon inflation caused by contrast injection through the guiding catheter has been observed during several angioplasty procedures. The phenomenon is observed when employing an 8F USCI guiding catheter in combination with an ACS dilatation catheter. Two cases demonstrating the phenomenon are described in detail, together with an in vitro experiment that illustrates and quantifies the mechanism.
 ...
PMID:Balloon inflation caused by contrast injection through the guiding catheter: an unusual observation during coronary angioplasty. 623 80

Adrenal demedullation combined with chemical sympathectomy with 6-hydroxydopamine (ACS) lowered plasma glucagon and insulin levels in rats. Acute cold exposure increased plasma glucagon in both ACS and control rats, while it increased plasma insulin only in ACS rats. ACS rats responded to cold with a smaller increase in plasma glycerol and a more pronounced elevation of plasma free fatty acids.
 ...
PMID:Effects of adrenal demedullation combined with chemical sympathectomy on cold-induced responses of endocrine pancreas in rats. 640 76

Amino acids enter rabbit jejunal brush border membrane vesicles via three major transport systems: (1) simple passive diffusion; (2) Na-independent carriers; and (3) Na-dependent carriers. The passive permeability sequence of amino acids is very similar to that observed in other studies involving natural and artificial membranes. Based on uptake kinetics and cross-inhibition profiles, at least two Na-independent and three Na-dependent carrier-mediated pathways exist. One Na-independent pathway, similar to the classical L system, favors neutral amino acids, while the other pathway favors dibasic amino acids such as lysine. One Na-dependent pathway primarily serves neutral L-amino acids including 2-amino-2-norbornanecarboxylic acid hemihydrate (BCH), but not beta-alanine or alpha-methylaminoisobutyric acid (MeAIB). Another Na-dependent route favors phenylalanine and methionine, while the third pathway is selective for imino acids and MeAIB. Li is unable to substitute for Na in these systems. Cross-inhibition profiles indicated that none of the Na-dependent systems conform to classical A or ACS paradigms. Other notable features of jejunal brush border vesicles include (1) no beta-alanine carrier, and (2) no major proline/glycine interactions.
 ...
PMID:Multiple transport pathways for neutral amino acids in rabbit jejunal brush border vesicles. 680 39

The paper discusses the results of a study of the case histories of 90 cancer patients. 48 of these patients received a course of treatment including physical rehabilitative therapy, dietotherapy, mesenchemotherapy (fractionated doses of ACS Bogomoletz, zymosan, splenin), oxygen and iodine-bromine baths, mineralized water and non-specific medication (vitamins, ext. eleutherococci, methonine, cholenzyme) and psychotherapy. It is suggested that non-specific therapy generally provided at health resort establishments is indicated in radically-operated stomach and breast cancer patients who reveal no signs of recurrence or metastases. Such therapy may contribute to social and occupational rehabilitation of cancer patients.
 ...
PMID:[Experience in rehabilitating cancer patients at sanatoria and health resorts]. 710 34

A mathematical model of cardiosignal (CS) based on the standard cardiosignals (SCS) is discussed. Algorithm for computing probability of arriving cardiosignal identity with one of the SCS classified by their clinical patterns is synthesized. Computations are based on the evaluation of similarity measure between ACS and SCS which is built as a likelihood logarithm. Mathematical-and-heuristical program development is executed and algorithm is realized with minimum computations and "size" of memorized ACS counts. By digital simulation algorithm serviceability is determined. The algorithm performs the following functions: scaling ACS with duration, normalizing, phase referencing and computing similarity measure according to the presented SCS sample.
 ...
PMID:[Statistical synthesis of an algorithm for the automatic processing of cardiosignals]. 714 73


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>