Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:5.99.1.3 (topoisomerase)
9,911 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA gyrase 0.102 DNA topoisomerase 0.084 topoisomerase I 0.024 topoisomerase II alpha 0.010 TOP2A 0.008 ICRF 0.006 DNA topoisomerase I 0.006 topoisomerase II beta 0.002 topo II beta 0.002 RMI1 0.002 TOP2B 0.002 TOP1 0.002 type I DNA topoisomerase 0.001 DNA topoisomerase III 0.001 TOP3 0.001 TDP1 0.001 RMI2 0.001 TOP2A protein 0.001 MLL 0.001 Tyrosyl-DNA phosphodiesterase 1 0.001 tyrosyl-DNA phosphodiesterase 1 0.001 TOP1mt 0.001 TOP1MT 0.001 SPO11 0.001 MX2 0.001 P-glycoprotein 0.001 ICB1 0.000 mitochondrial topoisomerase I 0.000 helicase 0.000 ATP 0.000 DNA topoisomerase II beta 0.000 TOP3A 0.000 PICH 0.000 TOP3B 0.000 H2AX 0.000 BLM 0.000 Mariner transposase 0.000 mdr1 0.000 p53 0.000 DNA-dependent protein kinase 0.000 more...

Disease cancer 0.001 leukemia 0.000 BLM 0.000 acute myeloid leukemia 0.000 Therapy-related myelodysplastic syndrome 0.000 CEM 0.000 tumor 0.000 L.donovani 0.000 vaccinia 0.000 ATM 0.000 secondary AML 0.000 MCF 0.000 mouse leukemia L1210 0.000 myelodysplastic syndrome 0.000 recurrent PNET 0.000 small cell lung cancer 0.000 WRN 0.000 breast cancer 0.000 MDS 0.000 acute promyelocytic leukemia 0.000 Teratoma with malignant transformation 0.000 Leukemia 0.000 SCAN1 0.000 colon cancer 0.000 acute lymphoblastic leukemia 0.000 lung cancer 0.000 SMC 0.000 ovarian cancer 0.000 lung carcinoma 0.000 acute leukemia 0.000 myeloid leukemia 0.000 carcinoma 0.000 non-small cell lung cancer 0.000 leukemogenesis 0.000 scleroderma 0.000 TAS 0.000 APL 0.000 PSS 0.000 solid tumor 0.000 lymphoma 0.000 more...

Symptom diarrhea 0.000 starvation 0.000 disturbed balance 0.000 ataxia 0.000 collapse 0.000 autodigestion 0.000 No adverse effect 0.000 HSA 0.000 nausea and vomiting 0.000 asthenia 0.000 Halo 0.000 decreased appetite 0.000 ophthalmoplegia 0.000 menopausal symptoms 0.000 nausea 0.000 dyspnea 0.000 apathy 0.000 eds 0.000 Hudson 0.000 hypoproteinemia 0.000 night sweats 0.000 muscle stiffness 0.000 vomiting 0.000 tonic-clonic seizure 0.000 skin damage 0.000 cerebellar ataxia 0.000 incoordination 0.000 chills 0.000 rhinorrhea 0.000 hyperoxia 0.000 dysuria 0.000 splenomegaly 0.000 fatigue 0.000 hoarseness 0.000 bone pain 0.000 colic 0.000 anorexia 0.000 cough 0.000 pelvic pain 0.000 syncope 0.000 more...

Drug Etoposide 0.004 Dexrazoxane 0.001 CPT-11 0.000 Teniposide 0.000 Adriamycin 0.000 Sobuzoxane 0.000 BLM 0.000 Pixantrone 0.000 TTC 0.000 Irinotecan 0.000 Aclarubicin 0.000 Gemifloxacin 0.000 DNase I 0.000 Gemifloxacin mesylate 0.000 Premafloxacin 0.000 Edotecarin 0.000 ADR 0.000 Sitafloxacin 0.000 MDS 0.000 Podophyllotoxin 0.000 Podophyllum 0.000 Idarubicin 0.000 Moxifloxacin 0.000 Mutagen 0.000 Avelox 0.000 Tetrahydropyran 0.000 Tirapazamine 0.000 Irofulven 0.000 Gluthathione 0.000 Ilmofosine 0.000 PZFX 0.000 Radicicol 0.000 VCR 0.000 Gatifloxacin 0.000 1,2,4-Triazole 0.000 Etoposide phosphate 0.000 Gemzar 0.000 VCR 0.000 Ofloxacin 0.000 Menogaril 0.000 more...

Enzyme topoisomerase 1.000 topoisomerase 0.910 P-glycoprotein 0.001 DNA polymerase 0.000 EC 5.99.1.1 0.000 DNA ligase 0.000 DNA ligase 0.000 PARP 0.000 ATPase 0.000 endonuclease 0.000 MDR 0.000 thymidylate synthase 0.000 RNA polymerase 0.000 ribonucleotide reductase 0.000 hydroxypyruvate isomerase 0.000 ribonucleotide reductase 0.000 caspase-3 0.000 cdc2 0.000 CPT 0.000 protein kinase 0.000 glutathione S-transferase 0.000 CPT 0.000 caspase-2 0.000 phosphodiesterase 0.000 RNase M5 0.000 kallikrein 10 0.000 CPT 0.000 caspase-2 0.000 polynucleotide kinase 0.000 micrococcal nuclease 0.000 ERK 0.000 DNase 0.000 DNase II 0.000 proteasome 0.000 polo-like kinase 1 0.000 dihydrofolate reductase 0.000 protein kinase C 0.000 nucleoside triphosphate phosphohydrolase 0.000 IMP dehydrogenase 0.000 S-formylglutathione hydrolase 0.000 more...

Compound m-AMSA 0.014 VP-16 0.009 DNA 0.005 VM-26 0.004 ICRF-187 0.002 Novobiocin 0.001 Camptothecin 0.001 Camptothecin 0.001 Camptothecin 0.001 Merbarone 0.001 Topotecan 0.001 Ellipticine 0.001 Topotecan 0.001 Adriamycin 0.001 SN-38 0.001 CPT-11 0.000 Fostriecin 0.000 Psorospermin 0.000 ATP 0.000 CI-921 0.000 Mitoxantrone 0.000 Mitoxantrone 0.000 ADR 0.000 acridine 0.000 benzo[a]phenazine 0.000 MIC 0.000 2,6-piperazinedione 0.000 BLM 0.000 Clorobiocin 0.000 Genistein 0.000 Podophyllotoxin acetate 0.000 N-ethylhydrazinecarbothioamide 0.000 Kinamycin C 0.000 C15H12O5 0.000 Fagaronine 0.000 C15H12O5 0.000 C15H12O5 0.000 8-Methoxycaffeine 0.000 C15H12O5 0.000 C15H12O5 0.000 more...

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