Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:5.99.1.3 (topoisomerase)
9,911 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ubiquitin specific peptidase 42 11.6
DNA topoisomerase 11.6
ELOF1 11.6
TOP1mt 11.6
LIX1L 11.6
shugoshin-like 2 11.6
Mariner transposase 11.6
topo II beta 11.4
ICB1 11.2
TOP2A protein 11.1
TOP1MT 11.1
C9orf82 11.1
DNA topoisomerase III 10.9
topoisomerase II beta 10.9
topoisomerase II alpha 10.8
DNA topoisomerase II beta 10.8
DNA gyrase 10.8
mitochondrial topoisomerase I 10.6
NLRP13 10.6
CKBBP2 10.6
SFRS7 10.6
PRRC1 10.6
human leucocyte antigen A 10.6
dedicator of cytokinesis 10 10.6
RMI2 10.6
exo-alpha-sialidase 10.6
TOP2B 10.6
RBP56/CHN 10.6
RMI1 10.6
type I DNA topoisomerase 10.5
TOP3 10.5
ICRF 10.5
TOP1 protein 10.3
TOP2 beta 10.3
TOP3A 10.3
Tyrosyl-DNA phosphodiesterase 1 10.2
TOP2A 10.2
MGC4175 10.1
irs-2 10.1
KIAA1210 10.1
TRAF interacting protein 10.1
splicing factor 4 10.1
TDRD3 10.1
TDP1 protein 10.1
TDP1 10.1
topoisomerase IIb 10.1
MOZ/CBP 10.1
SEPTIN6 10.1
Mucosal vascular addressin cell adhesion molecule 1 10.1
TOP3B 9.9
PICH 9.8
tyrosyl-DNA phosphodiesterase 1 9.7
topoisomerase I 9.7
Tudor domain-containing protein 3 9.6
TGF-beta activated kinase 9.6
cytochrome P450, family 2, subfamily D, polypeptide 6 9.6
DNA topoisomerase I 9.6
TOP1 9.6
FRYL 9.5
TRAF and TNF receptor-associated protein 9.5
ataxin 10 9.3
KIAA0020 9.3
DNA topoisomerase 2 9.3
Mitotic kinesin-like protein 1 9.3
ZNF214 9.3
SNF2, histone-linker, PHD and RING finger domain-containing helicase 9.3
HZW10 9.3
SFRS4 9.3
ICBP90 9.3
TTRAP 9.3
SPO11 9.3
SLFN11 9.2
HXA3 9.1
SARL 9.1
myeloid leukemia factor 2 9.1
MLL/AF4 fusion 9.1
TAFI110 9.1
PMX1 9.1
TGGCA-binding protein 9.1
Cys-X-Cys) 9.1
E1A-like inhibitor of differentiation 3 9.1
minichromosome maintenance complex component 4 9.1
Ribosomal protein L3 8.8
budding uninhibited by benzimidazoles 1 8.8
CAP-D2 8.8
40S ribosomal protein S12 8.8
SLC46A3 8.8
DNA topoisomerase 1 8.8
MX2 8.7
BTBD12 8.6
PKCI-1 8.6
PAK1IP1 8.6
RANGAP1 8.6
BIN3 8.6
D10S102 8.6
AML1/MDS1 8.6
GADD45 gamma 8.5
Cyclin-dependent kinase 11 8.5
ALL-1 protein 8.5
I-TRAF 8.5
V-1 protein 8.5
cell division cycle associated 8 8.5
MAK16 8.5
Metnase 8.5
uridine phosphorylase 1 8.5
HRX 8.5
rpl11 8.3
OTT-MAL 8.3
ZNF207 8.3
cysteine dioxygenase type 1 8.3
hCAP-C 8.3
BEN domain-containing protein 3 8.3
BLM protein 8.3
UBE3A protein 8.3
NCAPH 8.2
ICH-2 8.2
ribonuclease H2 8.2
APPBP2 8.2
Histone acetyltransferase 1 8.2
protein tyrosine phosphatase receptor type C 8.2
ZNF451 8.2
TNF receptor-associated protein 8.2
USP42 8.2
EME1 8.1
C-MYB 8.1
arginyl-tRNA-protein transferase 8.1
B99 8.1
homeobox B5 8.1
CARD6 8.1
omega protein 8.1
OTUD3 8.1
MUS81 8.0
RAD51-like 7.9
dihydropyrimidinase-like 2 7.9
PLGL 7.9
neural precursor cell expressed, developmentally down-regulated 8 7.9
ALL-1 7.9
HYAL-1 7.9
P1b 7.9
AD 3 7.8
SLD5 7.8
meltrin beta 7.8
RECQ5 7.8
PSF3 7.8
hPMC2 7.8
COX7B 7.8
RNF41 7.8
beta2-chimaerin 7.8
EEN 7.8
multidrug resistance associated protein 7.8
PRRP 7.7
PHRF1 7.7
CBF5 7.7
ZFM1 7.7
SGO2 7.7
pck2 7.7
Np95 7.7
centromere protein F 7.7
PASK 7.7
p180 7.7
Bloom's syndrome protein 7.6
MYM 7.6
ICH-1L 7.6
GGT2 7.6
FBXO5 7.6
RecA-like protein 7.6
ABCB8 7.6
Dbf4 protein 7.6
glutathione S-transferase pi 7.6
TRF4 7.6
NP95 7.6
SMC2 7.6
dual specificity phosphatase 5 7.6
SKI8 7.6
CDCREL1 7.6
BAZ1A 7.6
CGL-2 7.6
kinesin family member 20A 7.6
GADD45G 7.5
TopBP1 7.5
KIF4 7.5
TANC2 7.5
RAD9A 7.5
HPR1 7.4
ubiquitin D 7.4
MLL 7.4
RRN3 7.4
ATR-interacting protein 7.4
IARS 7.4
RDH11 7.4
TIPIN 7.4
RAD51-associated protein 1 7.4
cell division cycle associated 1 7.4
TEF3 7.4
claudin 16 7.4
cdc14 7.4
ABCF2 7.4
PGM5 7.4
Zhangfei 7.4
retinoic acid-induced protein 7.4
MDT1 7.4
TOP 7.4
RPA1 7.4
C10orf2 7.3
vacuolar H(+)-ATPase subunit 7.3
high mobility group 1 protein 7.3
MLL protein 7.3
HMGB4 7.3
POLA1 7.3
PSF2 7.3
CELF4 7.3
ATP6L 7.3
ZYX 7.3
PAPSS1 7.3
MDS1 7.3
single strand DNA-binding protein 7.3
Tissue inhibitor of metalloproteinase 1 7.3
MRX34 7.3
USP16 7.3
PTPRE 7.3
E2-EPF 7.3
CDK4I 7.3
Sur2 7.3
breakpoint cluster region 7.2
HLA-DRB1*08 7.2
ATP-hydrolysing 7.2
BLM 7.2
granzyme H 7.2
aprt 7.2
BRIT1 7.2
CDC14B 7.2
DDX10 7.2
SAE2 7.2
RecQ5 7.1
RAD51AP1 7.1
cell division cycle 20 7.1
SHPRH 7.1
histidyl tRNA synthetase 7.1
CTIP 7.1
MLP1 7.1
KIN17 7.1
RECQL5 7.1
p55CDC 7.1
Micrococcus luteus UV endonuclease 7.1
Desmoglein-2 7.1
CtIP 7.0
mdr1 7.0
actopaxin 7.0
RDH54 7.0
DUSP9 7.0
CBF-B 7.0
AF-4 7.0
Nuclear respiratory factor 1 7.0
Tyrosine protein kinase 7.0
SAF-A 7.0
multidrug resistance-related protein 7.0
ubiquitin protein ligase E3A 6.9
U11/U12 6.9
And-1 6.9
MER3 6.9
HELQ 6.9
maternal embryonic leucine zipper kinase 6.9
ZRANB3 6.9
methionine adenosyltransferase II 6.9
p15 protein 6.9
Tim13 6.9
mitogen-activated protein kinase 6 6.9
P-glycoprotein 1 6.9
MORC 6.9
Bloom syndrome 6.9
EAP30 6.9
RAD52 protein 6.9
Translin 6.9
synaptonemal complex protein 1 6.9
Btf 6.9
RAD6A 6.9
RNASEH2B 6.9
Werner syndrome helicase 6.9
CYP2W1 6.9
AGGF1 6.9
LRRFIP1 6.9
amphiphysin I 6.9
SLC28A3 6.9
NOMO 6.9
MLLT3 6.9
crn 6.8
WRAP53 6.8
ETO2 6.8
SNM1A 6.8
hBUB1 6.8
cyclin B2 6.8
MRP 6.8
RP-A 6.8
inositol polyphosphate-5-phosphatase 6.8
AML2 6.8
wus 6.8
SETMAR 6.8
XYLT2 6.8
70kD 6.8
ABCD4 6.8
ZMYND8 6.8
Claspin 6.8
L41 6.8
tripeptidyl-peptidase II 6.7
AMPD3 6.7
CDYL 6.7
PTPRB 6.7
WRN 6.7
telomerase-associated protein 1 6.7
RAD1 6.7
ML1 6.7
Ku86 6.7
SMARCAD1 6.7
GAS7 6.7
HDAC4 protein 6.7
germinal center-associated nuclear protein 6.7
RBP56 6.7
meiotic recombination 11 6.7
DNA polymerase theta 6.7
EDG-2 6.7
more...
Disease
recurrent PNET 10.6
Therapy-related myelodysplastic syndrome 9.6
L.donovani 9.6
Teratoma with malignant transformation 9.1
SCAN1 8.2
mouse leukemia L1210 8.0
FAB L2 7.8
childhood ependymoma 7.8
PanIN-1A 7.5
PanIN-1B 7.4
secondary AML 7.2
Axonal Neuropathy 7.2
Drug resistant tuberculosis 7.1
mouse leukemia P388 7.1
secondary myelodysplastic syndromes 7.1
urogenital gonorrhea 6.9
de novo myelodysplastic syndromes 6.9
Idiopathic hypoparathyroidism 6.7
Shope fibroma 6.7
amok 6.6
BLM 6.6
FPD/AML 6.5
bacterial conjunctivitis 6.5
AML/MDS 6.5
childhood ANLL 6.4
HER-2 positive breast cancer 6.4
adult soft tissue sarcoma 6.3
recurrent SCLC 6.2
Reovirus infection 6.2
CEM 6.1
PanIN-2 6.1
preneoplastic state 6.0
WRN 6.0
limited-stage small cell lung cancer 6.0
Argininosuccinic aciduria 6.0
SMC 5.9
Anaplastic carcinoma 5.8
PanIN-3 5.8
APL 5.8
MDS 5.7
Theileriosis 5.7
APL 5.7
trichomonal vaginitis 5.7
CREST 5.6
TAS 5.6
Subependymomas 5.6
MCPH1 5.6
stage III colorectal cancer 5.5
microbial disease 5.5
Infection induced 5.5
metastatic Ewing's sarcoma 5.5
MAR 5.4
FAB M2 5.3
ABC-DLBCL 5.3
vaccinia 5.3
small cell lung cancer 5.3
metastatic pheochromocytoma 5.2
Alpers 5.2
RAEB-T 5.1
Cerebral metastases 5.1
ATM 5.1
CNS cancer 5.1
RTS 5.1
squamous cell carcinoma of the anus 5.0
recurrent ovarian cancer 5.0
acute undifferentiated leukemia 5.0
in situ breast cancer 4.9
diffuse scleroderma 4.9
myeloid leukemia 4.9
APL 4.9
Gastrointestinal Tumor 4.9
histiocytic lymphoma 4.9
acute monocytic leukemia 4.9
XPF 4.9
MSF 4.8
adenocarcinoma of unknown primary 4.8
ODA 4.8
Craniopharyngioma 4.8
pediatric solid tumor 4.8
myelodysplastic syndrome 4.8
leukemogenesis 4.7
Brill 4.7
acute promyelocytic leukemia 4.7
acute myeloid leukemia 4.7
Traveler's diarrhea 4.7
mixed gliomas 4.7
PanIN 4.7
Enzyme inhibition 4.7
molluscum contagiosum 4.7
CPX 4.6
Photosensitized 4.6
AIDS-related lymphoma 4.6
TAM 4.6
RAEB 4.6
refractory cancer 4.6
adult AML 4.6
endomyometritis 4.5
African swine fever 4.5
recurrent cervical cancer 4.5
cancer angiogenesis 4.5
leukemia 4.5
FANCJ 4.5
histiocytic lymphoma 4.5
scleroderma 4.5
MCF 4.5
FA2 4.5
CHR 4.4
Malignant peripheral nerve sheath tumor 4.4
uterine sarcoma 4.4
acute leukemia 4.4
lymphoblastic leukemia 4.4
Staphylococcus aureus infection 4.4
stage II breast cancer 4.3
refractory cytopenia with multilineage dysplasia 4.3
lymphoblastoma 4.3
tonsillopharyngitis 4.3
xeroderma pigmentosum 4.3
HP1 4.3
indolent lymphoma 4.3
XPB 4.3
chronic myelomonocytic leukemia 4.2
XPD 4.2
Fanconi 4.2
solid tumor 4.2
lymphangiectasis 4.2
second cancer 4.2
RP4 4.2
Leukemia 4.1
HBT 4.1
adrenocortical cancer 4.1
FANCI 4.1
chronic enteritis 4.1
trisomy 9 4.1
monocytic leukemia 4.1
testicular teratoma 4.1
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
AT3 4.0
Chemoradiation 4.0
Drash syndrome 4.0
nagana 4.0
Sander 4.0
DRM 4.0
myelosuppression 4.0
stage III colon cancer 4.0
Fanconi syndrome 4.0
PSS 3.9
Gull 3.9
erythroleukemia 3.9
Angelman syndrome 3.9
Seckel syndrome 3.9
lymphoid neoplasm 3.9
Ovarian Cancer 3.9
testicular cancer 3.9
Malignant glioma 3.9
acute lymphoblastic leukemia 3.8
AT/RT 3.8
microsporidiosis 3.8
Pseudomonas infection 3.8
XPG 3.8
SAR 3.8
malignant meningioma 3.8
stage IV NSCLC 3.8
metaplastic carcinoma 3.7
Spitz nevus 3.7
lung carcinoma 3.7
testicular seminoma 3.7
Salmonellosis 3.7
HIV encephalopathy 3.7
mastocytoma 3.7
sarcoma 180 3.7
blast crisis 3.7
pediatric brain tumor 3.7
colon cancer 3.6
Larsen 3.6
pediatric AML 3.6
IS3 3.6
Spinocerebellar ataxia 3.6
ovarian cancer 3.6
SME 3.6
primary disorders 3.6
EMC 3.6
metastatic gastric cancer 3.6
MRSA 3.6
RSI 3.6
high-grade lymphomas 3.6
embryonal rhabdomyosarcoma 3.6
MPGN 3.6
premature aging 3.6
epithelial tumor 3.5
non-small cell lung cancer 3.5
childhood ALL 3.5
metastatic neuroblastoma 3.5
acute cystitis 3.5
megakaryocytic leukemia 3.5
PML 3.5
DDP 3.5
evaluable disease 3.5
acute nonlymphocytic leukemia 3.5
orf 3.4
Bradley 3.4
NPHP1 3.4
cervical adenocarcinoma 3.4
BEN 3.4
blood cancer 3.4
aggressive lymphoma 3.4
GCT 3.3
hormone refractory prostate cancer 3.3
fibrosarcoma 3.3
immunocytoma 3.3
Oral lichen planus 3.3
invasive thymoma 3.3
Cholangiocarcinoma 3.3
Liposarcoma 3.3
trisomy 8 3.3
epithelial ovarian cancer 3.3
adenocarcinoma of the pancreas 3.3
metastatic neuroblastoma 3.3
Febrile neutropenia 3.3
smallpox 3.3
pneumonic plague 3.3
CM1 3.2
high-grade squamous intraepithelial lesion 3.2
uterine cancer 3.2
Vogt 3.2
VISA 3.2
metastatic ovarian cancer 3.2
PEComa 3.2
PKS 3.1
sclerodactyly 3.1
adult ALL 3.1
HMR 3.1
African trypanosomiasis 3.1
Neuroblastoma 3.1
Neuroblastoma 3.1
retinoblastoma 3.1
neutropenia 3.1
germ cell tumor 3.1
stage III NSCLC 3.1
DMC 3.1
anal cancer 3.1
MTS 3.1
chronic leukemia 3.1
Robinson 3.0
L. infantum 3.0
glioblastoma 3.0
neck cancer 3.0
DLBCL 3.0
childhood cancer 3.0
hepatoblastoma 3.0
Raynaud 3.0
PNET 3.0
CAN 3.0
peritonsillar abscess 3.0
squamous cell lung cancer 3.0
anal cancer 3.0
anaplastic astrocytoma 3.0
PDC 3.0
Ewing's sarcoma 3.0
osteosarcoma 3.0
AOA 3.0
renal clear cell carcinoma 3.0
Mycoplasma 3.0
lung cancer 3.0
connective tissue disease 2.9
TCC 2.9
pancytopenia 2.9
CIN II 2.9
PDB 2.9
cancer 2.9
breast cancer 2.9
paroxysmal tachycardia 2.9
platelet disorder 2.9
esophageal dysmotility 2.9
MRD 2.9
VPI 2.9
Cholangiocarcinoma 2.9
keratocyst 2.9
gastrointestinal dysfunction 2.9
severe congenital neutropenia 2.8
esthesioneuroblastoma 2.8
B-cell chronic lymphocytic leukemia 2.8
bends 2.8
MPE 2.8
ABL 2.8
leishmaniasis 2.8
MDM 2.8
collagen disease 2.8
HTS 2.8
benign nevi 2.8
mammary tumor 2.8
Burkitt's lymphoma 2.8
LMS 2.8
gonococcal 2.7
papillary tumor 2.7
seminoma 2.7
sicca syndrome 2.7
myeloblastosis 2.7
NHL 2.7
Haemophilus 2.7
neuromyotonia 2.7
renal cancer 2.7
Li-Fraumeni syndrome 2.7
HNPCC 2.7
HML 2.7
adult T-cell leukemia/lymphoma 2.7
panuveitis 2.6
gynecologic cancer 2.6
adenocarcinoma of the lung 2.6
metastatic colon cancer 2.6
HGF 2.6
mantle cell lymphoma 2.6
PCD 2.6
multicentric Castleman's disease 2.6
more...
Symptom
disturbed balance 3.8
autodigestion 3.3
No adverse effect 3.3
Halo 2.8
decreased appetite 2.5
HSA 2.4
asthenia 2.3
menopausal symptoms 2.0
ophthalmoplegia 1.9
ataxia 1.6
eds 1.6
Hudson 1.6
nausea and vomiting 1.6
hypoproteinemia 1.5
starvation 1.5
night sweats 1.4
muscle stiffness 1.4
tonic-clonic seizure 1.3
apathy 1.2
diarrhea 1.2
collapse 1.1
skin damage 1.1
incoordination 0.9
cerebellar ataxia 0.8
chills 0.6
rhinorrhea 0.5
nausea 0.5
dysuria 0.4
hyperoxia 0.3
dyspnea 0.2
hoarseness 0.1
bone pain 0.0
colic 0.0
splenomegaly -0.0
vomiting -0.1
pelvic pain -0.3
hepatosplenomegaly -0.5
anorexia -0.5
syncope -0.5
paresthesia -0.6
hepatomegaly -0.9
hypotonia -0.9
cough -0.9
fatigue -1.0
erythema -1.0
abdominal pain -1.3
headache -1.5
seizures -1.8
weakness -2.0
sleepiness -2.0
functional recovery -2.1
exhaustion -2.1
acidity -2.2
discomfort -2.8
discomfort -2.9
pain -3.5
anesthesia -5.1
Drug
Sobuzoxane 11.1
Edotecarin 10.1
Premafloxacin 10.1
Pixantrone 9.6
Gemifloxacin mesylate 9.5
Dexrazoxane 9.3
Etoposide 9.3
Teniposide 9.3
Aclarubicin 9.0
Gemifloxacin 8.5
Sitafloxacin 8.3
Tetrahydropyran 8.1
Avelox 8.1
Gluthathione 7.9
Ilmofosine 7.9
PZFX 7.8
Podophyllotoxin 7.7
Irofulven 7.7
Etoposide phosphate 7.4
1,2,4-Triazole 7.4
CPT-11 7.3
Irinotecan 7.3
Podophyllum 7.3
Tirapazamine 7.2
Radicicol 7.2
BLM 7.1
Idarubicin 7.0
TTC 6.7
Menogaril 6.7
Adriamycin 6.5
Gatifloxacin 6.4
Moxifloxacin 6.4
Tarivid 6.2
Gemzar 6.1
ADR 5.9
Epidoxorubicin 5.9
MDS 5.9
Polysorbate 20 5.8
VCR 5.8
Gadoteridol 5.7
Gliadel 5.6
Rauwolfia serpentina 5.6
Myricetin 5.4
Xeloda 5.4
Compound 9 5.3
Enrofloxacin 5.2
Dronedarone 5.2
Compound 19 5.2
Vorinostat 5.2
Taxotere 5.2
Ofloxacin 5.2
Navelbine 5.1
Pirarubicin 5.1
DNase I 5.0
Novantrone 5.0
Compound 16 4.9
Vinorelbine 4.9
NOV 4.9
TEL 4.8
Vindesine 4.8
AraC 4.8
Poudre 4.8
Vindesine 4.7
VCR 4.7
Compound 15 4.7
Zevalin 4.6
Mutagen 4.6
Fludarabine 4.4
GEO 4.4
Pentostam 4.3
Atovaquone 4.2
Herceptin 4.2
Docetaxel 4.2
Filgrastim 4.2
CED 4.1
Pefloxacin 4.0
Taxol 4.0
Filgrastim 4.0
Flavopiridol 4.0
Diamminedichloroplatinum 3.9
Atovaquone 3.8
Glucantime 3.8
Emodin 3.8
Pyridoxal 3.6
Dihydro 3.6
KCL 3.6
ID2 3.5
ADM 3.5
Emodin 3.5
NovoSeven 3.4
Cremophor EL 3.4
CFS 3.3
DEL 3.2
Artesunate 3.2
K-252a 3.2
Asn 3.2
Amifostine 3.1
Retinoic Acid 3.1
Gefitinib 3.0
Pemetrexed 3.0
MDM 3.0
EPI 2.9
Fluconazole 2.9
Lovastatin 2.9
Trifluoperazine 2.9
Glutathione 2.8
caffeine 2.8
Photofrin 2.8
Alanine 2.8
Gleevec 2.7
PFT 2.7
Bortezomib 2.7
Zoledronic acid 2.7
MTC 2.7
CTX 2.6
CTX 2.6
Ranitidine 2.6
FLP 2.6
ACT 2.6
Doxycycline 2.6
Paraffin 2.6
Clofibrate 2.5
Meropenem 2.5
AMC 2.4
Dasatinib 2.4
CoCl2 2.4
CoCl2 2.4
R1881 2.3
Meropenem 2.3
ETS 2.3
AZT 2.3
Isotretinoin 2.3
Phosphatidylserine 2.3
Meth 2.2
-deoxyadenosine 2.2
CTX 2.1
ABC 2.1
ROS 2.1
Sorafenib 2.1
AZT 2.1
CDP 2.0
Gel 2.0
AGG 2.0
Zoledronic acid 2.0
TAC 2.0
Ouabain 1.9
MRC 1.9
Bevacizumab 1.9
NaI 1.8
NaI 1.8
NaI 1.8
NaI 1.8
Methylprednisolone 1.8
DEX 1.8
Oxaliplatin 1.8
Cetuximab 1.7
GRF 1.7
Itraconazole 1.7
lysine 1.7
ampicillin 1.6
G-CSF 1.6
CTC 1.6
IL-11 1.5
G418 1.5
Fragment 1.5
L-tyrosine 1.4
RFP 1.4
Azithromycin 1.4
PCP 1.4
Vitamin B 1.4
DPA 1.3
Fraction 1.3
CTC 1.3
ZnCl2 1.3
ZnCl2 1.3
FeCl3 1.2
Vitamin K 1.2
IPM 1.1
Amiloride 1.1
balanced salt solution 1.1
MAP 1.0
DM1 1.0
Triclosan 1.0
Gelatin 0.9
Norplant 0.9
Amiloride 0.8
p75 0.7
Dakar 0.6
Estrogens 0.5
Imatinib 0.4
Forskolin 0.3
Fluorescein 0.2
Rituximab 0.2
CAM 0.1
MOF 0.1
IFN-beta 0.1
CaCl2 0.0
CaCl2 0.0
CaCl2 -0.0
ascorbate -0.0
Retinoic acid -0.1
HCH -0.1
NH3 -0.1
Leaf -0.2
Fluorescein -0.2
niacin -0.2
Spectrum -0.3
Albumin -0.6
Angiotensin II -0.7
ICI -0.7
NADH -0.8
FAD -0.8
CSF -0.9
EPA -1.2
IL-2 -1.2
ROC -1.3
Spectrum -1.3
THF -1.3
lactose -1.4
Monit -1.4
citric acid -1.6
vitamin E -2.4
Nephron -2.5
Cardiovasc -3.1
IFN-gamma -3.2
Dermatol -3.2
Enzyme
topoisomerase 11.6
EC 5.99.1.1 11.6
topoisomerase 11.6
hydroxypyruvate isomerase 9.1
RNase M5 7.8
kallikrein 10 7.8
S-formylglutathione hydrolase 6.8
nucleoside triphosphate phosphohydrolase 6.6
dCMP hydroxymethylase 6.4
DNA ligase 6.1
DNA ligase 6.1
P-glycoprotein 6.0
endonuclease VII 5.9
DNase II 5.9
caspase-2 5.8
enzyme X 5.8
dCMP deaminase 5.8
AP lyase 5.8
polynucleotide kinase 5.7
caspase-2 5.6
thymidylate synthase 5.6
separase 5.6
lambda exonuclease 5.5
ribonucleotide reductase 5.5
MDR 5.5
dUTPase 5.3
bleomycin hydrolase 5.3
DNA polymerase 5.2
exonuclease V 5.2
deoxycytidine deaminase 5.2
ribonucleotide reductase 5.2
deoxycytidine kinase 5.2
IMP dehydrogenase 5.1
STK2 5.1
PIP kinase 5.0
PTR1 5.0
prolyl-tRNA synthetase 5.0
polo-like kinase 1 5.0
CPT 5.0
FabH 4.9
PARP 4.9
CPT 4.8
Escherichia coli exonuclease III 4.8
DSR 4.7
amidophosphoribosyltransferase 4.7
micrococcal nuclease 4.7
penicillopepsin 4.7
glutamate racemase 4.7
endodeoxyribonuclease 4.6
Protein 2 4.5
deoxyguanosine kinase 4.5
endonuclease 4.5
CPT 4.4
inosine triphosphatase 4.4
pseudouridine synthase 4.3
alanine racemase 4.3
cdc2 4.3
ubiquinol-cytochrome c oxidoreductase 4.3
enoyl-ACP reductase 4.2
3'-phosphatase 4.2
enoyl-ACP reductase 4.2
RNase H 4.2
ScpA 4.2
coproporphyrinogen III oxidase 4.2
pyruvate formate-lyase 4.1
phosphatidylserine decarboxylase 4.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.0
3'-exonuclease 4.0
dihydrofolate reductase 4.0
acyl carrier protein synthase 4.0
DNase 4.0
deoxyribonuclease 3.9
aspartase 3.9
GM3 synthase 3.9
poly(A) polymerase 3.9
RNA polymerase 3.8
chitin synthase 3.8
branched-chain aminotransferase 3.8
polyamine oxidase 3.8
iduronate-2-sulfatase 3.7
glucosylceramide synthase 3.7
NCP 3.7
peptide deformylase 3.7
prolidase 3.7
spermidine/spermine N1-acetyltransferase 3.7
DNA methyltransferase 3.7
caspase-6 3.7
proteinase K 3.7
coproporphyrinogen oxidase 3.7
phosphodiesterase 3.6
ATPase 3.6
dihydropteroate synthase 3.6
NADH-cytochrome b5 reductase 3.6
pyruvate oxidase 3.6
dihydropyrimidine dehydrogenase 3.6
pyruvate oxidase 3.6
thymidine kinase 3.6
nucleoside hydrolase 3.6
caspase-9 3.5
glutathione S-transferase 3.5
thymidylate kinase 3.5
caspase-7 3.4
caspase-1 3.4
carboxylesterase 3.4
MTD 3.4
LIS 3.4
S1 nuclease 3.4
deoxyribonuclease 3.4
caspase-7 3.4
cysteine synthase 3.4
penicillin binding protein 3.3
caspase-3 3.3
caspase-8 3.3
cytidine deaminase 3.3
NAT 3.3
orotate phosphoribosyltransferase 3.3
ceramidase 3.3
Fpg protein 3.2
disulfide reductase 3.2
thymidine phosphorylase 3.2
Lys4 3.2
tryptophanase 3.2
GCA 3.2
folylpolyglutamate synthetase 3.2
restriction-modification system 3.2
glycolate oxidase 3.2
hypoxanthine-guanine phosphoribosyltransferase 3.2
azoreductase 3.2
NQO1 3.1
nicotinamide phosphoribosyltransferase 3.1
asparaginase 3.1
ubiquitin-protein ligase 3.0
carboxypeptidase E 3.0
xylose isomerase 3.0
proteasome 3.0
argininosuccinate lyase 3.0
caspase-4 3.0
dihydropyrimidine dehydrogenase 3.0
choline oxidase 3.0
PST 2.9
dipeptidyl peptidase IV 2.9
4-epimerase 2.9
cruzipain 2.9
tryptophan 2,3-dioxygenase 2.9
cyclohydrolase 2.9
RNase 2.8
venom phosphodiesterase 2.8
firefly luciferase 2.8
Rex 2.8
TdT 2.8
histone demethylase 2.8
caspase-6 2.8
RNase 2.7
matriptase 2.7
kinesin 2.7
protein phosphatase 2A 2.7
chloramphenicol acetyltransferase 2.7
farnesyltransferase 2.6
Alternating 2.6
protein kinase 2.6
chaperonin 2.6
histone acetyltransferase 2.6
isopeptidase 2.5
CCS 2.4
protein kinase C 2.4
histidine kinase 2.4
TSA 2.4
thioredoxin reductase 2.4
lysyl oxidase 2.4
fumarate reductase 2.4
cathepsin L 2.3
neutral sphingomyelinase 2.3
PDH 2.2
phosphatidylinositol 4-kinase 2.2
adenine phosphoribosyltransferase 2.2
cathepsin B 2.2
ERK 2.2
transpeptidase 2.1
phosphoinositide 3-kinase 2.1
aldehyde oxidase 2.1
cytosine deaminase 2.1
farnesyltransferase 2.1
triphosphatase 2.1
N-acetyltransferase 2.0
peptidyl-prolyl cis-trans isomerase 2.0
demethylase 2.0
ornithine decarboxylase 2.0
CYP3A4 2.0
MDH 2.0
phosphorylase 2.0
beta-galactosidase 2.0
reverse transcriptase 2.0
IKK 2.0
MAP 2.0
BAT 1.9
MDH 1.9
PHD 1.9
sucrase-isomaltase 1.9
S-adenosylmethionine decarboxylase 1.9
luciferase 1.9
p100 1.8
sialidase 1.8
Pla 1.8
diaphorase 1.8
MEKK1 1.8
adenosine kinase 1.8
PRE 1.7
acyl-CoA oxidase 1.7
formate dehydrogenase 1.7
formate dehydrogenase 1.7
PTPase 1.7
ADP-ribosyltransferase 1.7
C3 convertase 1.6
ADP-ribosyltransferase 1.6
5alpha-reductase 1.6
5alpha-reductase 1.6
formate dehydrogenase 1.6
proprotein convertase 1.6
ribonuclease 1.5
ribonuclease 1.5
beta-lactamase 1.5
matrix metalloproteinase 2 1.5
mitogen-activated protein kinase 1.5
ATP synthase 1.5
CD13 1.4
Thy1 1.4
calcineurin 1.4
carbonic anhydrase 1.4
PCP 1.4
CPS 1.3
cellulose synthase 1.3
tyrosinase 1.3
MEK 1.3
carboxypeptidase Y 1.3
cellobiohydrolase 1.3
BMT 1.3
glutathione reductase 1.2
cathepsin D 1.2
MMP 1.2
gamma-glutamylcysteine synthetase 1.2
aequorin 1.1
TPP 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
histidine decarboxylase 1.1
MAT 1.1
PNGase F 1.1
beta-glucuronidase 1.1
isocitrate dehydrogenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.0
transcriptase 1.0
phosphatidylinositol 3-kinase 1.0
5'-nucleotidase 1.0
focal adhesion kinase 1.0
succinate dehydrogenase 1.0
aldehyde dehydrogenase 0.9
isocitrate dehydrogenase 0.9
MAT 0.9
succinic dehydrogenase 0.9
aconitase 0.9
glycerol-3-phosphate dehydrogenase 0.9
cathepsin G 0.8
glycerol-3-phosphate dehydrogenase 0.8
prolyl hydroxylase 0.8
endoglycosidase H 0.8
glutathione peroxidase 0.8
trypsin 0.8
enolase 0.8
glyceraldehyde-3-phosphate dehydrogenase 0.8
phospholipase D 0.8
thermolysin 0.8
botulinum neurotoxin 0.8
ACS 0.7
CaMKII 0.7
APC 0.7
neuraminidase 0.6
AMPK 0.6
HIV-1 protease 0.6
NADH dehydrogenase 0.6
glyceraldehyde-3-phosphate dehydrogenase 0.6
peroxidase 0.6
chymotrypsin 0.6
CAD 0.6
aldehyde dehydrogenase 0.5
aldehyde dehydrogenase 0.5
matrix metalloproteinase 9 0.5
CAD 0.5
aldehyde dehydrogenase 0.5
PDK1 0.5
GSK 0.5
CAD 0.5
malate dehydrogenase 0.5
hyaluronidase 0.5
catalase 0.5
alcohol dehydrogenase 0.5
transglutaminase 0.4
lactate dehydrogenase 0.4
glucose-6-phosphate dehydrogenase 0.3
MDP 0.3
pyruvate dehydrogenase 0.2
alkaline phosphatase 0.2
beta-glucosidase 0.2
acetyl-CoA carboxylase 0.2
diaphorase 0.1
complex I 0.1
hyaluronidase 0.0
thyroid peroxidase 0.0
furin 0.0
ricin 0.0
aldehyde dehydrogenase -0.0
CD10 -0.0
beta-glucosidase -0.0
papain -0.0
granzyme B -0.0
UDP-glucuronosyltransferase -0.0
pyruvate dehydrogenase -0.1
prostate-specific antigen -0.1
pyruvate dehydrogenase -0.1
nitrogenase -0.2
NOS -0.2
more...
Compound
C15H12O5 11.6
6-bromo-9H-purine 11.6
Kinamycin C 11.6
Podophyllotoxin acetate 11.6
C15H12O5 11.6
C15H12O5 11.6
1,3-bis(4-morpholinylmethyl)-2-imidazolidinethione 11.6
C15H12O5 11.6
8-Methoxycaffeine 11.6
C15H12O5 11.6
C15H12O5 11.6
N-ethylhydrazinecarbothioamide 11.6
Psorospermin 11.2
Merbarone 10.8
m-AMSA 10.7
Licodione 10.6
C37H40N2O6 10.6
Mitindomide 10.6
Lunacridine 10.6
Methoxycamptothecin 10.6
2-butanone thiosemicarbazone 10.6
Lunacridine 10.6
Albamycin 10.6
Usambarensine 10.6
abietan-18-oic acid 10.6
5H-indeno[1,2-b]pyridin-5-one 10.6
Elsamicin 10.3
benzo[a]phenazine 10.2
C2B4 10.1
C19H18O8 10.1
Voacamine 10.1
6-methoxy-5,8-quinolinedione 10.1
Fostriecin 10.0
Fagaronine 9.9
ICRF-187 9.9
2,6-piperazinedione 9.7
CI-921 9.7
Clorobiocin 9.6
C17H20N2O3 9.6
1-(phenylsulfonyl)-1H-indole 9.6
Ellipticine 9.6
Novobiocin 9.4
VM-26 9.4
Moxifloxacin hydrochloride 9.3
11H-indeno[1,2-b]quinoline 9.3
5,11-dimethyl-6H-pyrido[4,3-b]carbazole 9.3
11H-indeno[1,2-b]quinoline 9.3
Mulberrofuran G 9.3
Methanesulfonanilide 9.3
benzo[i]phenanthridine 9.3
Chloroquinoxaline sulfonamide 9.3
VP-16 9.1
Bimolane 9.1
C14H12O3 9.1
9-cis-Retinal 9.1
NMHE 9.1
2-hydroxynaphthoquinone 9.1
Cryptolepine 9.0
2-hydroxynaphthoquinone 8.9
2,3-dihydro-1H-cyclopenta[b]quinoline 8.8
Pinobanksin 8.8
Rubrofusarin 8.8
Topotecan 8.8
Camptothecin 8.8
beta-Lapachone 8.7
Camptothecin 8.7
Camptothecin 8.7
C18H18N2O5 8.6
Illudin S 8.6
[1,2,4]triazolo[1,5-a]pyridine 8.5
benzo[g]isoquinoline-5,10-dione 8.5
1-methyl-4-piperidinol 8.5
Toxoflavin 8.3
Nogalamycin 8.3
Sitafloxacin 8.3
Topotecan 8.3
Cyasorb 8.2
Wedelolactone 8.2
Quinalizarin 8.2
Diospyrin 8.2
6H-indolo[2,3-b]quinoxaline 8.2
Coumermycin 8.1
Rebeccamycin 8.1
Naringenin chalcone 8.1
9-chloroacridine 8.1
Butin 8.1
CI-941 7.9
Petroselinic acid 7.9
Piperlonguminine 7.8
Cubebin 7.8
Podophyllotoxin 7.8
SN-38 7.7
Podophyllotoxin 7.7
A 186 7.7
delta12,14-PGJ2 7.7
Mitoxantrone 7.7
Bulbocapnine 7.6
Lucanthone 7.6
benzo[c]phenanthridine 7.6
Mitoxantrone 7.6
Salicylaldoxime 7.6
Ametantrone 7.6
Chartreusin 7.6
Diaminopyridine 7.5
Deoxydoxorubicin 7.5
Xanthatin 7.4
Isofraxidin 7.4
Nalidixic acid 7.4
5-Formyluracil 7.3
1,3-thiazolidine-2-thione 7.3
CPT-11 7.3
2-phenylnaphthalene 7.3
Amonafide 7.3
Fraxetin 7.2
Mitox 7.2
5-Hydroxymethyluracil 7.2
Trovafloxacin 7.2
3-quinolinecarboxylic acid 7.2
ICRF 159 7.2
2-(4-morpholinyl)ethyl 7.1
ICRF 159 7.1
Isometamidium chloride 7.1
ICRF 159 7.1
Cuminaldehyde 7.1
4(1H)-quinolinone 7.1
1,3-thiazolidine-2-thione 7.1
2-(4-morpholinyl)ethyl 7.0
Xanthatin 7.0
Azidopine 7.0
I acid 6.9
7-oxabicyclo[2.2.1]heptane 6.9
BNS 6.9
3-fluoropyridine 6.9
2-(dimethylamino)ethyl 6.9
2-(dimethylamino)ethyl 6.9
Cucurbitacin I 6.9
Liriodenine 6.9
Solamargine 6.9
2,5-dihydroxyterephthalic acid 6.9
Hoechst dye 33258 6.9
Danthron 6.9
hydrazinecarbothioamide 6.9
1,2,4-benzenetriol 6.8
2-ethoxy-2-oxoethyl 6.8
9-AC 6.8
1H-benzo[de]isoquinoline-1,3(2H)-dione 6.7
2-amino-1-propanol 6.7
Imexon 6.7
1,4-dihydronaphthalene 6.7
Citronellal 6.7
AD 32 6.7
R-11 6.6
1H-indole-3-carbaldehyde 6.6
Tiazofurin 6.6
Aphidicolin 6.6
Aphidicolin 6.6
Gatifloxacin 6.6
Acridone 6.5
Niguldipine 6.4
PRPP 6.4
Moxifloxacin 6.4
Dibromodulcitol 6.4
Distamycin A 6.4
stigmast-4-en-3-one 6.4
Vinca 6.3
Novex 6.3
1-methylpiperazine 6.3
Genistein 6.3
Adriamycin 6.3
Harmine 6.3
C14H12N2 6.3
Digitoxin 6.3
2-pyridinecarboxylic acid 6.3
Fludarabine phosphate 6.3
Genistin 6.3
Nitidine 6.2
Berenil 6.2
BLM 6.2
Enoxacin 6.2
N-phenylbenzamide 6.1
3-chloropyridine 6.0
3-aminobenzamide 6.0
WR-1065 6.0
B17 6.0
ADR 6.0
Methyleugenol 6.0
Myricitrin 6.0
Phorbol-12,13-dibutyrate 5.9
ethyl propiolate 5.9
Samorin 5.9
Ciprofloxacin 5.9
Oxolinic acid 5.9
phenanthridine 5.9
Buthionine sulfoximine 5.9
phenanthridine 5.9
phenanthridine 5.9
Daunorubicin 5.9
9AA 5.8
Epirubicin 5.8
Diamminedichloroplatinum 5.8
9AA 5.8
Echinomycin 5.8
Grepafloxacin 5.8
Ethidium bromide 5.8
acridine 5.8
4H-pyrido[1,2-a]pyrimidin-4-one 5.7
HMBA 5.7
methanesulfonamide 5.7
methanesulfonamide 5.7
ara-AMP 5.7
ara-AMP 5.7
2-Aminopurine 5.6
Usnic acid 5.6
Eriochrome Black T 5.6
Norfloxacin 5.6
Carnosol 5.6
PALA 5.6
6-Thioguanine 5.6
Levofloxacin 5.6
Lycorine 5.6
[1,10]phenanthroline 5.6
Acetophenone 5.6
LNT 5.6
Garcinol 5.5
DVC 5.5
Nedaplatin 5.5
Lomefloxacin 5.5
3-hydroxyaspartic acid 5.5
Flubendazole 5.4
Betulinic acid 5.4
aceturate 5.4
Bufalin 5.4
DEK 5.4
Butein 5.3
MDR 5.3
HMBA 5.3
D-Galactosamine 5.3
XTP 5.3
D-Glyceraldehyde 5.3
2-methylquinoline 5.3
Isoliquiritigenin 5.3
N-ethylurea 5.3
Anthraquinone 5.3
Pentamidine 5.3
selenourea 5.3
Deoxyguanosine 5.2
6-aminonicotinamide 5.2
[1,10]phenanthroline 5.2
dATP 5.2
Ofloxacin 5.2
Daidzein 5.2
cyclopentanol 5.2
Hoechst 33342 5.2
Homoharringtonine 5.1
TCH 5.1
bis(2-chloroethyl) 5.1
SC-1 5.1
2-methylquinoline 5.1
SC-1 5.1
Propoxur 5.1
Sparfloxacin 5.0
Hydrocortisone acetate 5.0
Flavone 5.0
1,2,4-benzotriazine 5.0
Coumestrol 5.0
cinnoline 5.0
bis(2-chloroethyl) 5.0
2,6-dimethylpyridine 5.0
ADP-ribose 5.0
tris(2-chloroethyl) phosphate 5.0
CPT 5.0
Potassium permanganate 4.9
CPT 4.9
STP 4.9
TSC 4.9
2-hydroxy-1-naphthaldehyde 4.9
2-hydroxy-1-naphthaldehyde 4.9
2-hydroxy-1-naphthaldehyde 4.9
Aloe-emodin 4.9
Glyoxylate 4.9
Quinacrine 4.9
2-hydroxy-1-naphthaldehyde 4.9
2-hydroxy-1-naphthaldehyde 4.9
Herbimycin 4.9
Celastrol 4.9
Chloroacetaldehyde 4.9
methyl methanesulfonate 4.9
naphthoquinone 4.9
naphthoquinone 4.9
naphthoquinone 4.9
naphthoquinone 4.9
naphthoquinone 4.9
naphthoquinone 4.9
Suramin 4.8
TEL 4.8
Plumbagin 4.8
MIC 4.8
ETH 4.8
Benzene 4.8
2-hydroxy-1-naphthaldehyde 4.8
Quinone 4.8
5-methyltryptophan 4.8
2-hydroxy-1-naphthaldehyde 4.8
naphthoquinone 4.8
Thiazolidinedione 4.8
3,4-dihydroxybenzaldehyde 4.7
ATC 4.7
1H-pyrrole 4.7
Phosphoserine 4.7
1H-pyrrole 4.7
Z-Gly 4.7
quinoline 4.7
myricetin 4.7
quinoline 4.7
Vinblastine 4.7
Fisetin 4.7
ATC 4.7
Cinnamaldehyde 4.7
9H-xanthen-9-one 4.6
sedoheptulose 7-phosphate 4.6
more...