Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:5.99.1.3 (topoisomerase)
9,911 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein DNA gyrase 0.102 DNA topoisomerase 0.084 topoisomerase I 0.024 topoisomerase II alpha 0.010 TOP2A 0.008 ICRF 0.006 DNA topoisomerase I 0.006 topoisomerase II beta 0.002 topo II beta 0.002 RMI1 0.002 TOP2B 0.002 TOP1 0.002 type I DNA topoisomerase 0.001 DNA topoisomerase III 0.001 TOP3 0.001 TDP1 0.001 RMI2 0.001 TOP2A protein 0.001 MLL 0.001 Tyrosyl-DNA phosphodiesterase 1 0.001 more...

Disease cancer 0.001 leukemia 0.000 BLM 0.000 acute myeloid leukemia 0.000 Therapy-related myelodysplastic syndrome 0.000 CEM 0.000 tumor 0.000 L.donovani 0.000 vaccinia 0.000 ATM 0.000 secondary AML 0.000 MCF 0.000 mouse leukemia L1210 0.000 myelodysplastic syndrome 0.000 recurrent PNET 0.000 small cell lung cancer 0.000 WRN 0.000 breast cancer 0.000 MDS 0.000 acute promyelocytic leukemia 0.000 more...

Symptom diarrhea 0.000 starvation 0.000 disturbed balance 0.000 ataxia 0.000 collapse 0.000 autodigestion 0.000 No adverse effect 0.000 HSA 0.000 nausea and vomiting 0.000 asthenia 0.000 Halo 0.000 decreased appetite 0.000 ophthalmoplegia 0.000 menopausal symptoms 0.000 nausea 0.000 dyspnea 0.000 apathy 0.000 eds 0.000 Hudson 0.000 hypoproteinemia 0.000 more...

Drug Etoposide 0.004 Dexrazoxane 0.001 CPT-11 0.000 Teniposide 0.000 Adriamycin 0.000 Sobuzoxane 0.000 BLM 0.000 Pixantrone 0.000 TTC 0.000 Irinotecan 0.000 Aclarubicin 0.000 Gemifloxacin 0.000 DNase I 0.000 Gemifloxacin mesylate 0.000 Premafloxacin 0.000 Edotecarin 0.000 ADR 0.000 Sitafloxacin 0.000 MDS 0.000 Podophyllotoxin 0.000 more...

Enzyme topoisomerase 1.000 topoisomerase 0.910 P-glycoprotein 0.001 DNA polymerase 0.000 EC 5.99.1.1 0.000 DNA ligase 0.000 DNA ligase 0.000 PARP 0.000 ATPase 0.000 endonuclease 0.000 MDR 0.000 thymidylate synthase 0.000 RNA polymerase 0.000 ribonucleotide reductase 0.000 hydroxypyruvate isomerase 0.000 ribonucleotide reductase 0.000 caspase-3 0.000 cdc2 0.000 CPT 0.000 protein kinase 0.000 more...

Compound m-AMSA 0.014 VP-16 0.009 DNA 0.005 VM-26 0.004 ICRF-187 0.002 Novobiocin 0.001 Camptothecin 0.001 Camptothecin 0.001 Camptothecin 0.001 Merbarone 0.001 Topotecan 0.001 Ellipticine 0.001 Topotecan 0.001 Adriamycin 0.001 SN-38 0.001 CPT-11 0.000 Fostriecin 0.000 Psorospermin 0.000 ATP 0.000 CI-921 0.000 more...

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